Presented by Sothyra Tum (FAO) to the Progress Meeting on Ecosystem Approaches to the Better Management of Zoonotic Emerging Infectious Diseases in the South East Asian Region, Bangkok, 10-13 December 2011.
USDA APHIS Veterinary Vervice: One Health call to actionHarm Kiezebrink
Interest in the One Health approach is surfacing in both the public and private sector within the USA. Members of the US Congress have demonstrated their support of One Health principles by introducing legislation to promote, implement, and sustain veterinary services, and veterinary public health; to promote training in food systems security; to develop strategies to address antimicrobial resistance; and to develop other veterinary health initiatives.
The private sector understands that harnessing the combined expertise of medical and veterinary science can transform the ability to control and eradicate a range of pathogens that pose major threats to both human and animal health, and that undermine the viability of livestock agriculture and food production. As part of its vision for 2015, APHIS Veterinary Service is committed to embrace One Health strategy as part of the solution to address the changes and challenges of the APHIS Veterinary Service landscape.
Presented by Hung Nguyen-Viet and Jakob Zinsstag at a technical workshop of the Food and Agriculture Organization of the United Nations (FAO) regional initiative on One Health, Bangkok, Thailand, 11–13 October 2017.
Presented by Sothyra Tum (FAO) to the Progress Meeting on Ecosystem Approaches to the Better Management of Zoonotic Emerging Infectious Diseases in the South East Asian Region, Bangkok, 10-13 December 2011.
USDA APHIS Veterinary Vervice: One Health call to actionHarm Kiezebrink
Interest in the One Health approach is surfacing in both the public and private sector within the USA. Members of the US Congress have demonstrated their support of One Health principles by introducing legislation to promote, implement, and sustain veterinary services, and veterinary public health; to promote training in food systems security; to develop strategies to address antimicrobial resistance; and to develop other veterinary health initiatives.
The private sector understands that harnessing the combined expertise of medical and veterinary science can transform the ability to control and eradicate a range of pathogens that pose major threats to both human and animal health, and that undermine the viability of livestock agriculture and food production. As part of its vision for 2015, APHIS Veterinary Service is committed to embrace One Health strategy as part of the solution to address the changes and challenges of the APHIS Veterinary Service landscape.
Presented by Hung Nguyen-Viet and Jakob Zinsstag at a technical workshop of the Food and Agriculture Organization of the United Nations (FAO) regional initiative on One Health, Bangkok, Thailand, 11–13 October 2017.
The guidelines are intended to help countries identify priorities, objectives and the desired goal of disease control programmes. Disease control programmes are often established with the aim of eventual eradication of agents at a country, zone or compartment level. While this approach is desirable, the needs of stakeholders may require a broader range of outcomes. For some diseases, eradication may not be economically or practically feasible and options for sustained mitigation of disease impacts may be needed. It is important to clearly describe the programme goals and these may range from simple mitigation of disease impacts to progressive control or eradication of the disease. These guidelines highlight the importance of economic assessment of disease intervention options in the design of programmes taking into consideration effectiveness, feasibility of implementation, as well as costs and benefits. The purpose is to provide a conceptual framework that can be adapted to a particular national and epidemiological context.
Keynote presentation by Dr Delia Grace of the International Livestock Research Institute, Nairobi, at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, London 17-18 March 2016
One Health – an interdisciplinary approach in combating emerging diseasesILRI
Presentation by Hung Nguyen-Viet, Delia Grace and Jakob Zinsstag at the International Symposium of Health Sciences (iSIHAT 2013), Kuala Lumpur, Malaysia, 20-21 August 2013.
Presentation by Fred Unger at a training course for the Philippine Council for Agriculture, Aquatic and Natural Resources Research and Development (PCAARRD) project team, Pampanga, the Philippines, 30-31 July 2014.
GRF One Health Summit 2012, Davos: Presentation by Francisco.REVIRIEGO, Policy Officer - Legislative veterinary officer - Head of Sector, Animal health, EU
Measuring and evaluating resilience in drylands of East Africa: Managing impa...ILRI
Presented by Bernard Bett at the IFPRI 2020 Policy Consultation and Conference, Side Event on Measuring and Evaluating Resilience in Drylands of East Africa, Addis Ababa, 15-17 May 2014
Presented by Jeff Gilbert at a meeting on sharing the experiences on the application of One Health approaches in China, Beijing, China, 8-9 August 2013.
Social dimensions of zoonoses in interdisciplinary researchNaomi Marks
Presentation by Dr Hayley MacGregor of the Institute of Development Studies, UK, at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, 17-18 March 2016.
Progetto BEPS: Action Plan 1 – Digital Economy
Sulla base della relazione finale 2015 diramata dall’OCSE, pubblichiamo il primo di una serie di articoli concernenti le 15 azioni del Progetto BEPS. L’azione N. 1 (ADDRESSING THE TAX CHALLENGES OF THE DIGITAL ECONOMY), riguarda le sfide della fiscalità nella Digital Economy.
The guidelines are intended to help countries identify priorities, objectives and the desired goal of disease control programmes. Disease control programmes are often established with the aim of eventual eradication of agents at a country, zone or compartment level. While this approach is desirable, the needs of stakeholders may require a broader range of outcomes. For some diseases, eradication may not be economically or practically feasible and options for sustained mitigation of disease impacts may be needed. It is important to clearly describe the programme goals and these may range from simple mitigation of disease impacts to progressive control or eradication of the disease. These guidelines highlight the importance of economic assessment of disease intervention options in the design of programmes taking into consideration effectiveness, feasibility of implementation, as well as costs and benefits. The purpose is to provide a conceptual framework that can be adapted to a particular national and epidemiological context.
Keynote presentation by Dr Delia Grace of the International Livestock Research Institute, Nairobi, at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, London 17-18 March 2016
One Health – an interdisciplinary approach in combating emerging diseasesILRI
Presentation by Hung Nguyen-Viet, Delia Grace and Jakob Zinsstag at the International Symposium of Health Sciences (iSIHAT 2013), Kuala Lumpur, Malaysia, 20-21 August 2013.
Presentation by Fred Unger at a training course for the Philippine Council for Agriculture, Aquatic and Natural Resources Research and Development (PCAARRD) project team, Pampanga, the Philippines, 30-31 July 2014.
GRF One Health Summit 2012, Davos: Presentation by Francisco.REVIRIEGO, Policy Officer - Legislative veterinary officer - Head of Sector, Animal health, EU
Measuring and evaluating resilience in drylands of East Africa: Managing impa...ILRI
Presented by Bernard Bett at the IFPRI 2020 Policy Consultation and Conference, Side Event on Measuring and Evaluating Resilience in Drylands of East Africa, Addis Ababa, 15-17 May 2014
Presented by Jeff Gilbert at a meeting on sharing the experiences on the application of One Health approaches in China, Beijing, China, 8-9 August 2013.
Social dimensions of zoonoses in interdisciplinary researchNaomi Marks
Presentation by Dr Hayley MacGregor of the Institute of Development Studies, UK, at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, 17-18 March 2016.
Progetto BEPS: Action Plan 1 – Digital Economy
Sulla base della relazione finale 2015 diramata dall’OCSE, pubblichiamo il primo di una serie di articoli concernenti le 15 azioni del Progetto BEPS. L’azione N. 1 (ADDRESSING THE TAX CHALLENGES OF THE DIGITAL ECONOMY), riguarda le sfide della fiscalità nella Digital Economy.
Accountants, are you ready for the US?
In the United States, the fiscal powers of taxation is based on three levels: federal, state and municipal. The federal income tax, in particular, is a pay-as-you-go tax.
From November 7 to 10, the Italian accountants will stay in New York city, on a mission in the US. We went to look around the contents by the IRS (Inland Revenue Service) in the field of “Tax Withholding and Estimated Tax”, for use in 2016.
The federal income tax is a pay-as-you-go tax. You must pay the tax as you earn or receive income during the year. There are two ways to pay-as-you-go: Tax Withholding and Estimated Tax.
Hijab instan model Hoodie yang simple dan dapat langsung dipakai dan sangat mudah diaplikasikan dengan
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Lecture 2 the information system by an accountant's prospective- ais an over...Habib Ullah Qamar
The Information System: an Accountant’s Prospective
Today we will discuss importance of AIS from an accountant in an organization. After this we will be able to place AIS in prospective of an accountant.
M. Com Annual Part 2 University of Punjab at Govt. College of Commerce Gurjanwala
One Health: A Holistic Approach to Achieving Global Well-beinggreendigital
Introduction:
In an interconnected world where the boundaries between humans, and animals. and the environment blurred. One Health has emerged as a comprehensive approach to addressing complex health challenges. One Health recognizes the intricate connections between the Health of humans and animals. and ecosystems, emphasizing the need for collaborative efforts across disciplines to achieve optimal well-being for all. This article delves into the fundamental principles of It, and its historical roots. and its potential to revolutionize the way we approach global Health.
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Understanding One Health:
A- Definition and Scope:
It is an integrative approach that considers the Health of humans, animals. and the environment as interdependent entities. It acknowledges that the Health of one component influences the Health of the others. and disruptions in any of these systems can have far-reaching consequences. This approach goes beyond traditional silos in health management. and embraces a holistic perspective. recognizing the intricate web of connections that shape our Health.
B- Historical Roots:
The roots of the It concept can traced back to ancient civilizations. where the interconnectedness of human and animal health acknowledged. But, the formal recognition of It as a distinct field gained momentum in the late 20th century. The emergence of zoonotic diseases transmitted between animals. and humans highlighted the need for a collaborative approach to disease prevention and control.
Key Principles of One Health:
A- Interdisciplinary Collaboration:
At the heart of It is interdisciplinary collaboration. This principle involves breaking down the traditional barriers between medical, veterinary. and environmental sciences. Professionals from various fields work together to understand the complex dynamics of Health. and to develop effective strategies for prevention, surveillance, and response to emerging threats.
B- Zoonotic Disease Surveillance:
Given the increasing frequency of zoonotic disease outbreaks. It emphasizes surveillance and early detection. Monitoring diseases at the human-animal-environment interface is crucial for identifying potential threats before. they escalate into global pandemics. This proactive approach involves close collaboration between public health agencies. veterinary services, and environmental monitoring bodies.
C- Environmental Stewardship:
It recognizes the impact of environmental degradation on Health. Climate change, deforestation, and pollution can exacerbate the spread of diseases. affect water and food sources, and compromise the well-being of ecosystems. Integrating environmental stewardship into health policies is essential for safeguarding the Health of present and future generations.
Examples of One Health in Action:
A- Pandemic Preparedness:
The ongoing COVID-19 pandemic has underscored the importance of a It approach. The virus, believed to have originated in bats.
The roles of livestock and farmed wildlife in preventing the next pandemic: C...ILRI
Presentation by Hung Nguyen-Viet, Delia Grace, Bernard Bett, Johanna Lindahl and Dieter Schillinger at a virtual workshop on countering zoonotic spillover of high consequence pathogens, 12 July 2022.
One Health approach to address zoonotic and emerging infectious diseases and ...ILRI
Presentation by Hung Nguyen-Viet, Hu Suk Lee, Fred Unger, Arshnee Moodley, Eric Fèvre, Barbara Wieland, Bernard Bett, Michel Dione, Edward Okoth, Johanna Lindahl, Sinh Dang-Xuan and Delia Grace at the virtual 2020 Global ODA Forum for Sustainable Agricultural Development 9–10 November 2020.
Presented by Habibur Rahman and Vijayalakshmy Kennady (ILRI) at the Strategy Workshop on Foodborne Diseases, National Academy of Agricultural Sciences, New Delhi, India, 21 November 2019
Dr. Lonnie King - Future of Animal AgricultureJohn Blue
Future of Animal Agriculture - Dr. Lonnie King, Acting Dean, College of Food, Agriculture and Environmental Sciences, The Ohio State University, from the 2017 NIAA Annual Conference, U.S. Animal Agriculture's Future Role In World Food Production - Obstacles & Opportunities, April 4 - 6, Columbus, OH, USA.
More presentations at http://www.trufflemedia.com/agmedia/conference/2017_niaa_us_animal_ag_future_role_world_food_production
GRF One Health Summit 2012, Davos: Presentation by Dr. Berhe Tekola - Director - Animal Production and Health - Food and Agriculture Organization of the United Nations FAO
One Health and zoonoses projects at the International Livestock Research Inst...ILRI
Presentation by Theo Knight-Jones at the Capacitating One Health in Eastern and Southern Africa (COHESA) partner orientation workshop, 16 December 2021.
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neurochemical systems and has rewarding and addictive properties. It
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mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
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from mild to severe. A diagnosis of AUD requires that at least two of
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AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
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STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Emerging and Zoonotic Diseases – Strengthening Surveillance Systems
1. Emerging and Zoonotic Diseases –
Strengthening Surveillance Systems
Peter Daniels
Deputy Director, Australian Animal Health Laboratory, Geelong, Australia
CSIRO Animal, Food and Health Science
Presentation for Plenary Session V, 2nd GRF One Health
Summit 2013, Davos, Switzerland, 17- 20 November, 2013
2. What should be the Future?
A Glimpse of the purpose of this surveillance?
Is it too aspirational to suggest that
Where animals are farmed to meet the needs of
society, an informed society will require that the
farming of these animals will not result in a
health threat to people
Pandemic Threats and Animal Agriculture Page 2
3. The Role Call of Emerging Infectious
Diseases Problems - and “Near Misses”
•
•
•
•
•
Nipah Virus in Pigs in Malaysia ... 295 (120)
Highly pathogenic avian influenza H5N1 ... 630 (375)
Ebola-Reston in pigs in the Philippines several (0)
Pandemic H1N1 2009 globally .... ongoing
Variant H3N2 in North American pigs ... Several
hundred infections
• Avian influenza A(H7N9) in China ... 134 (43)
(Just examples where intensively farmed animals
have been a significant factor)
4. The Chatham House
Centre on Global Health Security
Project title: Tensions between Human and
Animal Health
Reviewing current policies and collaboration between the human,
animal and trade sectors to identify possible obstacles and
solutions
Often identification of an infectious agent occurs in
humans after human-to-human spread has begun, rather
than in the animal from which it comes, and
opportunities for control in animals and prevention of
human infection are lost
Chatham House (2010) Shifting from Emergency Response to
Prevention of Pandemic Disease Threats at Source
5. Infections are transmitted among animals aided by
human value chain behaviours
Hence a holistic (One health?)
understanding is the basis of
managing the risks of animal disease
But the understanding is needed by each
society as whole: Farmers, traders, advisors,
industry managers, regulators, consumers
And the people at the critical control
points have to CARE enough to want to
manage the risk– to do it!
Pandemic Threats and Animal Agriculture Page 5
6. Early recognition of new threats gives better
prospects for their eradication
“The concept of emerging threats must be integrated into
National Animal Health regulations and should be included
in the remit of the Veterinary Services”
But is it just the veterinary services? Can they be everywhere?
Farmers and farming enterprises are the front line
of society at the human animal interface!
The animal farming operation is the critical control
point in the value chain for surveillance
Pandemic Threats and Animal Agriculture Page 6
7. Delivery on our over-arching proposition, responding to
Chatham House type concerns,
requires a priori detection!
THE SOLUTION? THE VISION?
Managers of intensively farmed animals will know the
infection status of their enterprise, just as they know
the data of any production-related aspect of the
business, and communicate findings
Pandemic Threats and Animal Agriculture Page 7
8. Possible surveillance issues for producers
1. Who carries the cost?
• In a world where the public are represented by the
supermarkets, how can surveillance costs be
recovered?
1. What will be the response to findings?
• Regulatory issues affecting business continuity – the
first rule of surveillance:
Don’t do it unless you know what you are going to do
with the findings
• Public perception issues relating to profitability –
spontaneous market boycotts
9. A Glimpse of the Future?
Consequently there is a need for public-private
cooperation to deliver effective surveillance of animal
populations for emerging health threats:
Managing the Human Animal Interface
Monitoring the infection status of farmed animals
is a basic approach to disease risk management
“Understanding the complex dynamics that define the food animal
ecosystem of the 21st century is central to mitigating risks of
emerging zoonoses” (Leibler et al, 2009, Ecohealth)
Pandemic Threats and Animal Agriculture Page 9
10. Prerequisites for a new way of doing business
based on real time surveillance 1.
The human factor: farm owners and managers have to
be committed, the public has to understand the process
Foreseeable impediments:
• Costs – who pays, and how?
• Negative repercussions following detections – threats to
business continuity – need informed and predictable regulations
Immediate needs:
• Advocacy for partnership between public and producers
• Social science/behavioural science research along the value
chain
• Communications strategies - but with what messages?
Pandemic Threats and Animal Agriculture Page 10
11. Prerequisites for a new way of doing business
incorporating real time surveillance 2.
The technological challenges and opportunities
New detection technologies are becoming available
• The challenge is to choose among them
• Investigate how best to use them
• Validate them
Which approach will be most cost effective?
Pandemic Threats and Animal Agriculture Page 11
12. Alignment of the need for surveillance with Global
Megatrends - (Megachallenges)
1. Demographics – more people, more elderly (disease susceptible?)
2. Enabling technologies – novel opportunities
3. International interconnectedness – multinational food companies
4. Public debt – The challenge to reduce public debt while finding
new ways to deliver public services and outcomes
5. Resources stress (climate change, water, competing land uses) –
efficient agricultural resource management to guarantee food
6. Urbanization – 60% of people will live in cities – 37 megacities:
(intensification of human production with similar implications for
disease transmission),
a disconnect between biological understanding and the
immediate environment?
Future State 2030: The global megatrends shaping
governments, Mowat Centre, KPMG, 2013
13. Response strategies required to address
megachallenges
What needs to change?
• Behaviour among citizens – better informed to be part of the
solution to the management of impacts
• Value chain behaviours – supported by policies and regulations
• Systems for managing the international dimensions
How to change?
• Re-thinking of current paradigms
• Strategy development based on behavioural insights
• Adoption of new technologies
Future State 2030: The global megatrends shaping
governments, Mowat Centre, KPMG, 2013
14. Over to our panel.................
Thank you
CSIRO Australian Animal Health Laboratory
Peter Daniels, Deputy Director
t +61 3 5227 5014
e peter.daniels@csiro.au
w www.csiro.au
CSIRO Animal, Food and Health Science
Editor's Notes
How else can the risk of emergence of zoonotic disease threats in intensively farmed animals be managed? What are the lessons from Nipah, SARS, H5N1, pandemic H1N12009,variant H3N2 in pigs, Ebola Reston in pigs in the Philippines etc?