The document discusses various strategies for animal disease control including prevention, vaccination, biosecurity measures, surveillance, zoning/compartmentalization, and stamping out. It emphasizes applying the appropriate strategy based on factors like the disease, its impacts, stakeholders involved, and available resources. The overall goal is to reduce disease prevalence and impacts in a cost-effective manner.
Peste des Petits Ruminants (PPR) in India Epidemiology and ControlBhoj Raj Singh
PPR is endemic in India in sheep & goats. Mainly young stocks are more affected. Disease occurs throughout the year but more common in October & March. Though vaccination is the only method for control & eradication, even the institutes those developed the effective vaccine in India to control the disease fear to use it because many a time outbreaks ensue on vaccination. The other important reason for persistence of disease is undeclared Policy of suppressed reporting of PPR outbreaks.
Control and Eradication of Animal diseases.pptxBhoj Raj Singh
The presentation details different methods and terminologies used in disease management. It briefs about different types of disease control programs run at global, regional, and national levels. It also tells about the success and failure of different disease control programs. The presentation also briefed about methods of disease control.
Foot and mouth disease preventive and epidemiological aspectsBhoj Raj Singh
FMD: Menace in India
Discusses problems of FMD Control in India like:
Lack of faith in farmers and veterinarians that FMD can be controlled with vaccination (due to repeated failure of vaccines in quality and vaccination failures resulting in FMD outbreaks).
Lack of infrastructure facilities for maintaining the cold chain and efficient transport to the vaccination site.
Lack of human resources for handling/ vaccinating livestock.
Needs for further researches on diagnosis (Pen-side), disinfection, vaccines and vaccination (affording at least a year immunity, quality vaccine etc.) and control strategies.
No-timely investigation or excessively delayed investigation of FMD outbreaks especially those occurring after vaccination.
Transparency in vaccine quality monitoring and vaccine purchases.
Fear in veterinarians for reporting FMD in their area of operation.
False statistics of the disease and vaccination.
No legal punitive action against suppliers of substandard FMD vaccines even after the supply of multiple substandard batches of vaccine.
Peste des Petits Ruminants (PPR) in India Epidemiology and ControlBhoj Raj Singh
PPR is endemic in India in sheep & goats. Mainly young stocks are more affected. Disease occurs throughout the year but more common in October & March. Though vaccination is the only method for control & eradication, even the institutes those developed the effective vaccine in India to control the disease fear to use it because many a time outbreaks ensue on vaccination. The other important reason for persistence of disease is undeclared Policy of suppressed reporting of PPR outbreaks.
Control and Eradication of Animal diseases.pptxBhoj Raj Singh
The presentation details different methods and terminologies used in disease management. It briefs about different types of disease control programs run at global, regional, and national levels. It also tells about the success and failure of different disease control programs. The presentation also briefed about methods of disease control.
Foot and mouth disease preventive and epidemiological aspectsBhoj Raj Singh
FMD: Menace in India
Discusses problems of FMD Control in India like:
Lack of faith in farmers and veterinarians that FMD can be controlled with vaccination (due to repeated failure of vaccines in quality and vaccination failures resulting in FMD outbreaks).
Lack of infrastructure facilities for maintaining the cold chain and efficient transport to the vaccination site.
Lack of human resources for handling/ vaccinating livestock.
Needs for further researches on diagnosis (Pen-side), disinfection, vaccines and vaccination (affording at least a year immunity, quality vaccine etc.) and control strategies.
No-timely investigation or excessively delayed investigation of FMD outbreaks especially those occurring after vaccination.
Transparency in vaccine quality monitoring and vaccine purchases.
Fear in veterinarians for reporting FMD in their area of operation.
False statistics of the disease and vaccination.
No legal punitive action against suppliers of substandard FMD vaccines even after the supply of multiple substandard batches of vaccine.
Animal Disease Control Programs in India.pptBhoj Raj Singh
India is a hyperendemic country for many animal diseases and zoonotic diseases. Every year billions of rupees are spent on disease control, surveillance, monitoring, and vaccination against vaccine-preventable diseases. However, due to the failure of most animal disease control programs for one or other reasons India directly losses about 20 and 25 thousand crores annually due to endemicity of FMD & brucellosis, respectively. The presentation describes the pros and cons of different ongoing disease control programs going on in India.
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
Ongoing disease control programmes in indiaBhoj Raj Singh
Animal Husbandry, Dairying and Fisheries sectors play an important role in the national economy and in the socio-economic development of the country. Livestock sector alone contributes 4.11% towards overall National GDP and 25.6% of total Agriculture GDP. The biggest impediment to growth of this sector, however, is the large-scale prevalence of diseases such as Foot and Mouth Disease (FMD), Hemorrhagic Septicemia (HS), Brucellosis, Black Quarter (BQ) in cattle, Enterotoxaemia, Peste des Petits Ruminants (PPR) & Sheep-Goat Pox in sheep and goats and Swine Fever in pigs, which drastically affect the productivity of animals. The presence of this disease not only deters the domestic economy but also foreign investment in the livestock sector. Although India have been free from disease like Rinderpest, Contagious Bovine Pleuropneumonia (CBPP), Bovine Spongiform Encephalopathy (BSE), presence of other economically important disease still threaten the very roots of livestock sector. This presentation describes various control programs that have been introduced by the Government of India, nationwide for controlling the infectious diseases of animals that have been or should be targeted for eradication or elimination, direct and indirect benefits from control programs, drawback issues and opportunities for the future.
There are hundreds of diseases of livestock and pet animals that can be printed through properly used quality vaccines. This presentation summarises different types of vaccines used by veterinarians to control/ prevent diseases. The presentation enlists the vaccine-preventable diseases of pets and livestock, and also the different vaccines used.
Whether your dog is a working companion, champion show animal, hunting partner, or just a best friend, the kindest and most responsible thing you can do for him is to provide proper health care.
Knowing about common dog diseases and being aware of appropriate prevention and treatment can better help you provide that care.
Many Diseases Can Be Prevented .Some of the most common and serious dog diseases have been made less common through vaccines: however, these diseases continue to threaten a dog that lacks proper immunization. Puppies many be vaccinated as early as 4-6 weeks depending on each situation and the veterinarian’s advice. Through mother’s milk, puppies receive disease fighting antibodies, which last 6-16 weeks. Vaccinations then take over.
Yearly boosters should be given throughout your dog’s life, including old age when your dog may become more susceptible to some diseases.
Bovine tuberculosis epidemiology & control in indiaBhoj Raj Singh
Tuberculosis in India is in hyperendemic state both in human and animals. No DOTS can help in control of human tuberculosis unless tuberculosis is controlled in animals. Control of tuberculosis in animals is a far reacheachable dream in India and thus the Tuberculosis will persist in India till the dooms day.
Animal Disease Control Programs in India.pptBhoj Raj Singh
India is a hyperendemic country for many animal diseases and zoonotic diseases. Every year billions of rupees are spent on disease control, surveillance, monitoring, and vaccination against vaccine-preventable diseases. However, due to the failure of most animal disease control programs for one or other reasons India directly losses about 20 and 25 thousand crores annually due to endemicity of FMD & brucellosis, respectively. The presentation describes the pros and cons of different ongoing disease control programs going on in India.
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
Ongoing disease control programmes in indiaBhoj Raj Singh
Animal Husbandry, Dairying and Fisheries sectors play an important role in the national economy and in the socio-economic development of the country. Livestock sector alone contributes 4.11% towards overall National GDP and 25.6% of total Agriculture GDP. The biggest impediment to growth of this sector, however, is the large-scale prevalence of diseases such as Foot and Mouth Disease (FMD), Hemorrhagic Septicemia (HS), Brucellosis, Black Quarter (BQ) in cattle, Enterotoxaemia, Peste des Petits Ruminants (PPR) & Sheep-Goat Pox in sheep and goats and Swine Fever in pigs, which drastically affect the productivity of animals. The presence of this disease not only deters the domestic economy but also foreign investment in the livestock sector. Although India have been free from disease like Rinderpest, Contagious Bovine Pleuropneumonia (CBPP), Bovine Spongiform Encephalopathy (BSE), presence of other economically important disease still threaten the very roots of livestock sector. This presentation describes various control programs that have been introduced by the Government of India, nationwide for controlling the infectious diseases of animals that have been or should be targeted for eradication or elimination, direct and indirect benefits from control programs, drawback issues and opportunities for the future.
There are hundreds of diseases of livestock and pet animals that can be printed through properly used quality vaccines. This presentation summarises different types of vaccines used by veterinarians to control/ prevent diseases. The presentation enlists the vaccine-preventable diseases of pets and livestock, and also the different vaccines used.
Whether your dog is a working companion, champion show animal, hunting partner, or just a best friend, the kindest and most responsible thing you can do for him is to provide proper health care.
Knowing about common dog diseases and being aware of appropriate prevention and treatment can better help you provide that care.
Many Diseases Can Be Prevented .Some of the most common and serious dog diseases have been made less common through vaccines: however, these diseases continue to threaten a dog that lacks proper immunization. Puppies many be vaccinated as early as 4-6 weeks depending on each situation and the veterinarian’s advice. Through mother’s milk, puppies receive disease fighting antibodies, which last 6-16 weeks. Vaccinations then take over.
Yearly boosters should be given throughout your dog’s life, including old age when your dog may become more susceptible to some diseases.
Bovine tuberculosis epidemiology & control in indiaBhoj Raj Singh
Tuberculosis in India is in hyperendemic state both in human and animals. No DOTS can help in control of human tuberculosis unless tuberculosis is controlled in animals. Control of tuberculosis in animals is a far reacheachable dream in India and thus the Tuberculosis will persist in India till the dooms day.
Dr. Jim Logan - Emergency Response Preparedness: Considerations for the Small...John Blue
Emergency Response Preparedness: Considerations for the Small Ruminant Industry - Dr. Jim Logan, State Veterinarian, Wyoming Livestock Board, from the 2016 NIAA Annual Conference: From Farm to Table - Food System Biosecurity for Animal Agriculture, April 4-7, 2016, Kansas City, MO, USA.
More presentations at http://www.trufflemedia.com/agmedia/conference/2016_niaa_farm_table_food_system_biosecurity
Public health is dependent on animal health in rural areas because poor animal health directly affects the human food supply. Veterinary public health entails the diagnosis, surveillance, epidemiology, control, prevention and elimination of Zoonoses. Unsatisfactory implementation of stringent disease control, meat inspectorate and drug dispensation legislations prevents the efficient production of food of animal origin; creating obstacles to international trade in animals and animal products and hence an impediment to overall socioeconomic development
The guidelines are intended to help countries identify priorities, objectives and the desired goal of disease control programmes. Disease control programmes are often established with the aim of eventual eradication of agents at a country, zone or compartment level. While this approach is desirable, the needs of stakeholders may require a broader range of outcomes. For some diseases, eradication may not be economically or practically feasible and options for sustained mitigation of disease impacts may be needed. It is important to clearly describe the programme goals and these may range from simple mitigation of disease impacts to progressive control or eradication of the disease. These guidelines highlight the importance of economic assessment of disease intervention options in the design of programmes taking into consideration effectiveness, feasibility of implementation, as well as costs and benefits. The purpose is to provide a conceptual framework that can be adapted to a particular national and epidemiological context.
Dr. Lonnie King - One Health Antibiotic Stewardship - What MUST Be Done Next:...John Blue
One Health Antibiotic Stewardship - What MUST Be Done Next: Prioritizing Immediate Actions - Dr. Lonnie King, Professor and Dean Emeritus, College of Veterinary Medicine, The Ohio State University, from the 2017 NIAA Antibiotic Symposium - Antibiotic Stewardship: Collaborative Strategy for Animal Agriculture and Human Health, October 31 - November 2, 2017, Herndon, Virginia, USA.
More presentations at http://www.swinecast.com/2017-niaa-antibiotic-symposium-antibiotic-stewardship
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
4. An Overview of Sugarcane White Leaf Disease in Vietnam.pdf
Animal Disease Control
1. Animal
Disease
Control
Training on AppliedVeterinary Epidemiology and Animal Disease Diagnosis for Animal
Health Research Personnel,
Central Luzon State University Science City of Munoz , Nueva Ecija, 23-27 May 2016
Noemi Diloy- Encarnacion, DVM, MVetEpi
Assistant Professor 1
Cavite State University
Don Severino Delas Alas Campus, Indang,
Cavite
2. Session objectives
At the end of this topic, the
participants should be able to:
• Assess the importance of local
diseases based on selected criteria;
• Distinguish prevention, control and
eradication; and
• Describe the various strategies for
animal disease control.
6. ANIMAL DISEASE MANAGEMENT
Reduction, elimination or eradication of
livestock and poultry diseases and the
prevention of the introduction or outbreak of
foreign or domestic diseases.
7. Prevention - prevent disease occurrence
Disease control - reduction of the prevalence of
a disease to a level where it is no longer
considered a major health and/or economic
problem
8. Disease elimination – near eradication stage
– WHO (1991) defines it as “reduction of prevalence
to a level below one case per million population
Eradication - total elimination of a disease
– no further cases of a disease occurring anywhere,
and continued control measures are unnecessary
9. OIE GUIDELINES FOR OBTAINING RECOGNITION AS
BEING FREE FROM AN EPIZOOTIC DISEASE
• Stage 1: Provisional Freedom from Disease
– Absence of disease from the country
– No vaccination
• Stage 2: Freedom from Disease
– Ceased vaccination for a prescribed period
– No outbreaks of the disease
– Surveillance
• Stage 3: Freedom from Infection
– Absence of causative agent
– Preventive measures
10. How do you know a good disease
control officer?
1. He/she knows how to make a “priority” list
2. He/she responds quickly
3. He/she can mobilize the right persons for the
task: diagnose, control, and monitor disease
problems.
4. He/she can control the disease with the least
cost.
11. Choose the disease to control
PublicHealthSignificance Impactonthelivestockindustry
1. What zoonotic diseases occur more
frequently?
2. What zoonotic diseases cause severe
sicknessinhumans?
3. Presentmortalityandmorbidityrates
1. How easily is the disease transmitted
fromfarmtofarm?
2. Whatarethelossesduetomorbidity?
3. Whatarethelossesduetomortality?
4. What are the effects on trade and
commerce?
12. Prioritization
• Ranking of items based on their “perceived or
measured importance or significance”
• LIMITED RESOURCES
15. Estimate the MonetaryValue
Cost of disease Cost of disease
control
Benefits of disease control
Costs due to mortality
costs due to morbidity
Costs associated with
treatment
Extra labor to nurse the sick
animals
Prohibition of sales of animal
products (ex. milk)
Increase in food conversion
index
Impact on trade
Diagnostic tests
Vaccines
Drugs
Travel costs
Staff costs
Vehicles
Equipment
Genetic loss due to
the slaughter policy
etc.
Benefit =
Losses due to the disease without control project
− Losses due to the disease with control project =
16. RATIONALE FOR ESTABLISHING A
DISEASE CONTROL PROGRAM
1. the disease situation
2. disease impacts (animal and public health,
food safety, food security, biodiversity and
socioeconomic impact) and how these are
distributed among stakeholders
3. identity, level of interest and involvement of
stakeholders
17. Stakeholder Interest Influence/Importance Issueswith thestakeholder Strategy
CVMBS,CVSU Prestige. To be recognized as a veterinary
institution that is not only capable of
providing quality instruction but also
promoting and providing relevant
research and extension activities.
Indirectly a form of promotion that will
attract more enrollees and thus will
increaseits incomeandbudget allocation.
High Getting support fromtheuniversity
Contributions in implementing a
control program will be recognized by
local executives andpublic
Present a paper to the
university on the program to
include benefits, etc and the
support university willget
All activities will have the logo
of the university, will be
bannered as in cooperation with
theuniversity,etc.
PVO,MAO A good opportunity to promote and
achieve one of their goals on safeguarding
animal health from highly contagious
diseases suchas rabies
High Obtaining linkages
Their offices will be highly recognized in
theprogram implementation
The fact that it is them who are
primarily responsible in the control of
animal diseases in the province or
municipality and thus shall be the one
initiating theproject
A memorandum of
understanding that shall lay out
the ground rules of a positive
cooperativeeffort.
The names of their offices will
be mentioned/ posted in all
activities
This issue will be
considered/addressed in the
memorandum ofagreement
Collaborating Agencies (Provincial Health Officer,
Animal BiteCenter)
Rabies elimination in the human
population
High There is alack of
mutual understanding of and
accounting for differences in individual
agency missions, of objectives and in
the case of the health sector,
differences in the approach of disease
prevention, detection and control, and
of the full range of impacts of disease
control efforts in animal and human
health.
Formulate efficient
communication system by
bringing the heads of these
agencies together to develop a
sharedgoal for an integrated,
coordinated disease control
program and to define the roles
ofeach collaborating agency
18. CONTROL PROGRAM GOALS
• desired results or impacts that a control
program envisions, plans and commits to
achieve
“As is”
situation
“To be” situation
Control
Program
19.
20. a. Improve control of swine respiratory diseases
in Bulacan
b. Control and management of surra in the
Philippines
21. CONTROL PROGRAM OUTCOME,
OUTPUTS, ACTIVITIES
Outcome ___________
Output 1. ___________
Activity 1.1. __________
Activity 1.2. __________
Output 2. ___________
Activity 2.1. __________
Activity 2.2. __________
Output 3. ___________
Activity 3.1 __________
Etc.
NOUN/ADJECTIVES
Brief statement describing the change that the
program is expected to generate in a target group
at a specified time
Something
accomplished
Something to be done
VERBSORADVERBS
22. Examples:
Outcome: The strategy programenvisions thePhilippines to control and manage surra by 2025 such that
incidencewouldbenearly0bythatdate.
ExpectedOutput:1. Greaterunderstandingontheepidemiologyofsurra
CorrespondingActivities:
1.Trainingonsurrasurveillance
2.Conductsurveillance toestablishtrueprevalenceofsurra.
23. • Vaccination coverage of 80% of dog population
– Establish vaccination SOPs/guidelines
– Form teams and brief on SOPs and guidelines
– Inform public about dog rabies vaccination
– Etc…
• Increased level of awareness on rabies based
on established parameters
– conduct a knowledge, attitudes, practices survey of
the community folks on rabies
– analyze the results
– develop IEC campaign based on the KAP survey
– Implement IEC campaign
24. RISKS and ASSUMPTIONS
• plan for them and to mitigate their impact on
the project
Figure1: RiskMatrix
Risk Impact Probability Mitigation
1.
2.
Assumptions are the conditions needed to achieve results
after the risks have been managed
27. Determinants
• factors or events that are capable of bringing
about a change in health
• Influencing factor or characteristic
– introduction, development, and spread of disease
and other health-related conditions within and
between animals
28.
29. • On-Farm Biosecurity - measures adopted to
keep diseases out of herds where they do not
currently exist
– Isolation of new animals brought to the farm
– Restriction on movement of people, animals, and
equipment
– Use of safe feeds- Swill feeding can be dangerous
– Hygiene. Effective combination of cleaning and
disinfection
33. Vaccination
Purposes:
• To prevent disease establishment
– employed if there is an imminent or sustained threat
of the disease arriving
– what proportion of the susceptible population is
vaccinated (ex: herd immunity)
• To slow the spread of disease
– undertaken in an attempt to prevent more animals
becoming infected, thereby slowing or stopping the
geographic spread of the disease
34. Herd Immunity
>> form of indirect protection from infectious
disease that occurs when a large percentage of
a population (70-80%) has become immune to
an infection
>> providing a measure of protection for
individuals who are not immune
35.
36. • Ring vaccination – animals surrounding an
infected farm are vaccinated
• Blanket vaccination - vaccination of all
susceptible species/animals over a larger area
37. VaccinationTips
• Choose the safe and correct antigenic type.
• Maintain vaccine quality- no contamination, potency, etc.
• Follow the recommended vaccination coverage (preferably
70 %)
• Mark vaccinated animals
• Monitor proper storage temperatures for vaccines
• Organize trained personnel into “clean” and “dirty” teams
• Remember that gathering different herds together in one
vaccination station maybe convenient but dangerous.
• Count your needles and bottles before and after
vaccination.
38. Strategies to reduce the magnitude
of existing disease
• case finding & isolation
• contact tracing & quarantine
• “Resting” of farm or premises- length is not less than
the survival time of the pathogen.
• Slaughter of susceptible animals
• Closure of livestock markets and other congregations
of susceptible species (e.g. livestock auction markets,
race meetings and livestock exhibit/shows)
• Removal of animals from areas with high insect
population
• Treatment, medication
39. Zoning and Compartmentalization
• Procedures defining subpopulations of
distinct health status within an area.
• Disease control, international trade
Zoning subpopulation defined primarily on a
geographical basis (using natural, artificial or legal
boundaries)
Compartmentalization subpopulation defined
primarily by management and husbandry practices
related to biosecurity
40. STAMPING OUT
• Destruction (quick and humane) of large number
of animals
• Serious risk of further spread of disease
– animals in the infected zone are not well controlled
– spillover to feral animals
– inadequate resources are available for surveillance
and imposition of quarantine and controls
– public health risk
41. Factors to consider before implementing the
“slaughter” strategy
1. LIVESTOCK OWNER
2. METHOD
3. COMPENSATION
>>Way to ensure cooperation
4. COMMUNITY ACCEPTANCE
Editor's Notes
Diseases are one of the major reasons of our existence as veterinarians and animal health practitioner as they are the primary constraint to a sustainable livestock and poultry production and trade. Disease is not a threat to farmers alone but also to the whole agricultural sector and the national economy.
Diseases or disease agents are causing varying degrees of mortalities and morbidities which are affecting the overall animal productivity, farmers have their targets which they fail to achieve due to the losses related to diseases. Few days ago, according to the news…
Sadly, The main drag to the economic growth is the agricultural sector. In the hog industry and poultry industry and notable decrease in stocks were due to diseases.
Disease is considered a sturdy barrier to trade. Now that we are in the direction of globalization, with the implementation of the ASEAN FREE TRADE, there will be an expanded market for our agricultural products, however, this market may be limited by the presence of disease. Asean Free Trade will also allow an increase flow of goods to the country, including livestock and poultry and their by products, IMPLICATION: increase risk of disease
We as an epidemiologist must learn to manage risks.
Prevention is directed to diseases/disease agents that are not yet present in an area. The goal is to prevent disease occurrence. This may also imply early detection and rapid response in cases of emerging and reemerging disease..
Disease control on the other hand is applicable to diseases that are already present in an area, persistent, prevalent disease. The goal is the reduction of prevalence. Disease control also means disease containment and transmission control. In disease control the prevalence of a disease is decreased to a level that it is no longer considered a major health and or economic problem.
Disease elimination and eradication have been used interchageably, but these are two different concepts.
Disease elimination is near eradication stage, it is somewhere between disease control and disease eradication. The goal of elimination is the reduction of disease prevalence to zero or low cases. Meaning, the disease may still occur sporadically and control measures must still be in place.
Eradication on the other hand is the total elimination of disease. Freedom of disease. There are no further cases of disease occurring and therefore control measures are unneccessary. Freedom from disease is a very important status, especially when it comes to trade.
Qualities that each one of us should possess.
Prioritization is done to correctly or appropriately allocate limited resources, financial, time and effort to diseases that really requires control. Prioritizing diseases for control is not an easy process. It is a complex value judgement but has to be based on a scientific evidence.
Simplex, is a simple method where group perception is obtained with the use of a questionnaire. It is quick to do however the reliability of the result depends upon the quality of the formulated questions and the target repospondents.
The nominal group planning on the other hand, makes use of a panel of experts, whose individual judgements are sought.
The rationale is the platform to present the problem. It is the justification of the disease control program and must explain the epidemiological situation of the disease.
Goals are also referred to as IMPACTS and this is the desired result or outcome of a disease control program. Traditionally eradication has been the goals of many disease control program, however it is not always achievable in a given time frame at a given cost. Goals may be any of the following: PREVENTION, CONTROL, ELIMINATION OR ERADICATION or a combination of these.
Goal or impact is also a statement of the perceived contribution of the program to broader society.
The goal of a control program must be carefully crafted taking into consideration: the epidemiology of the disease, availability of technical tools, control measures and socio economic situation.
Outcome has previously been described as objectives SPECIFIC, MEASURABLE, ATTAINABLE, REALISTIC, TIME-BOUND.
Current approach is to state the objective as outcome in one brief statement which describes the change that the project is expected to generate in the target group at a specified time Outcome is the result of the outputs and the outputs are the result of the activities
THE OUTLINED OUTPUTS Product Breakdown Structure
The outlined activities Work Breakdown Structure
Not necessarily to AVOID RISKS but to plan for them and to mitigate their impact.
There are various methods of disease management and in crafting a disease control program, the decision on which control strategies to be used, depends on the understanding of the disease epidemiology. .. As we all know disease has a multifactorial in nature, meaning it results from the interaction of several factors that may be presented in an epidemiologic triad,
Disease is multifactorial and results from the interaction of several factors which may be grouped into 3, presented as an epidemiologic triangle, host factors, agent factors and the environmental factors…
As I have said earlier,
Designing of biosecurity measures depends on the correct identification of risk factor and managing these risks. Biosecurity practice may vary from farm to farm and vary depending on the disease that will be addressed. But the idea of biosecurity set of preventive measures designed to reduce the risk of transmission of infectious diseases in crops and livestock, quarantined pests, invasive alien species, and living modified organisms (Koblentz, 2010).
Swill feeding “identified risk” in the transmission of disease for instance FMD.. Several outbreaks of FMD occurring around the world were linked to swill feeding.
Another important measure to stop or slow the spread of disease is border control. Use of highly sensitive tests or detection methods that will allow inclusion of all who or anything are possibly disease positive or carrying disease at the border, either on entry to or exit from a country, so that they can be placed in isolation or prevented from traveling and spreading the disease elsewhere; however, this strategy is useful only if the intended goal is successfully achieved. Other potential benefits of border screening relate to increasing public awareness about and confidence in protection from the disease in question
Strict enough to prevent entry of exotic diseases but liberal enough to encourage legal importations. Quarantine protocols must be negotiated with the exporting country for the safe importation of animals, germplasm and animal products. Strict Observance of export and import protocols
Depending on the disease, a waste management protocol should be develop.
If it is a huge disease control project, it is a requirement to seek for an ECC or an Environmental Compliance Certificate from DENR-Environmental Management Board
>>> proposed project or undertaking will not cause a significantly negative impact on the Philippine environment.
ND – Newcastle disease, a disease affecting birds, where preventive vaccination is permitted on a routine basis. Because the presence of the disease in wild birds present a continuing threat to domesticated birds and poultry.
Depending upon the epidemiological advice, susceptible animals most at risk of the disease could be vaccinated first, which may or may not mean vaccinating animals geographically close to known infected premises. Advice is sought from experts on what the priority areas are in light of the risk situation and how quickly a specified vaccination area should be widened, if and when necessary. Depending on the disease situation, experts may advise targeting vaccination in one of several ways:
Depending upon the epidemiology, identification of the at risk population, the disease situation, availability of vaccines
Vaccination may be done in several ways:
Ring vaccination vaccination of all susceptible animals in a prescribed area around an outbreak . Creation of an immune belt around an infected zone. may be done to contain a very rapidly spreading disease outbreak or in situations where the effectiveness of other methods to prevent the spread of the disease in and around infected zones, e.g. quarantine and livestock movement controls, cannot be guaranteed, or where these areas may be relatively inaccessible.depends for its success on the rapidity by which diagnosis, typing the virus and vaccination are carried out. The size and shape of the Vaccination area is declared based on the circumstances of an outbreak. Vaccination would begin at both the centre and the periphery of the area
Evidence from previous epidemics that ring vaccination with stamping out is effective. Vaccination may be carried out in conjunction with the slaughter of the infected animals and those that have been in contact with them
Blanket vaccination - vaccination of all susceptible species animals over a larger area may be the preferred option when the disease outbreak has become well established and there are multiple foci of infection, or when other disease control methods are impractical for one reason or another. The vaccination area should cover known and suspected infected areas together with those areas considered to be at high risk for spread of the disease. The latter may include known livestock movement routes. It may be necessary to carry out several rounds of vaccination over a few years in the target area, until the clinical disease apparently disappears, or the incidence is at least reduced to a level where other disease control measures can be followed
Zoning – encourage the more efficient use of resources --> infected zone, containment zone buffer zone, free zone
Basis for trade
Stamping out is often the most cost-effective strategy. The disease eradication campaign is shorter and achieved for a lower overall cost and there is a shorter waiting period before the country can be recognized as free of the disease and resume export of livestock and animal products.
Several social, economic and other factors need to be evaluated before stamping out is selected as the strategy for a disease contingency plan. These include:
whether or not slaughter of infected animals is likely to gain community acceptance on religious, ethnic, animal welfare and other social and economic grounds;
advantages, disadvantages and likely success of implementation of other strategies;
(In this context it should be noted that vaccination is not available for some epidemic livestock diseases and stamping out is the only viable option. African swine fever is such a disease. At the other end of the spectrum, for some diseases stamping out is unlikely to have much effect. This particularly applies to insect-borne diseases such as Rift Valley fever and bluetongue.)
whether or not the manpower, equipment, and other physical resources are available to carry out all activities needed for the implementation of a stamping-out campaign;
(Whilst stamping out is likely to be less costly and more efficient overall, it may be quite resource-intensive in the short term.)
whether adequate provisions are available for fair and quick compensation of owners for livestock or property destroyed in the campaign.
Well organized veterinary services that have the full political support of the government are crucial to the success of the disease-eradication campaign. The full support of other services such as the police, army and public works is essential. The final important element is prior preparation of a comprehensive contingency plan for the disease in question.
This manual does not discuss strategic issues. For these, reference should be made to the FAO Manual on the preparation of national animal disease emergency plans and manuals on preparation of contingency plans for specific diseases such as rinderpest and African swine fever.
This is a procedures manual: how to carry out important activities in a disease stamping-out campaign. It is divided into three parts:
Destruction of animals
Disposal procedures
Decontamination
Several social, economic and other factors need to be evaluated before stamping out is selected as the strategy for a disease contingency plan. These include:
whether or not slaughter of infected animals is likely to gain community acceptance on religious, ethnic, animal welfare and other social and economic grounds;
advantages, disadvantages and likely success of implementation of other strategies;
(In this context it should be noted that vaccination is not available for some epidemic livestock diseases and stamping out is the only viable option. African swine fever is such a disease. At the other end of the spectrum, for some diseases stamping out is unlikely to have much effect. This particularly applies to insect-borne diseases such as Rift Valley fever and bluetongue.)
whether or not the manpower, equipment, and other physical resources are available to carry out all activities needed for the implementation of a stamping-out campaign;
(Whilst stamping out is likely to be less costly and more efficient overall, it may be quite resource-intensive in the short term.)
whether adequate provisions are available for fair and quick compensation of owners for livestock or property destroyed in the campaign.
Well organized veterinary services that have the full political support of the government are crucial to the success of the disease-eradication campaign. The full support of other services such as the police, army and public works is essential. The final important element is prior preparation of a comprehensive contingency plan for the disease in question.
This manual does not discuss strategic issues. For these, reference should be made to the FAO Manual on the preparation of national animal disease emergency plans and manuals on preparation of contingency plans for specific diseases such as rinderpest and African swine fever.
This is a procedures manual: how to carry out important activities in a disease stamping-out campaign. It is divided into three parts: