The document discusses One Health approaches and their implementation. It provides the following key points: 1. One Health aims to achieve optimal health outcomes for humans, animals and the environment through cross-sectoral collaboration. It addresses challenges like zoonotic diseases which affect both human and animal health. 2. Implementing One Health in practice involves mapping disease burdens, ensuring food safety, and understanding barriers and enablers. The "unlucky 13" zoonoses cause billions of cases and millions of deaths annually. 3. There are significant economic benefits to controlling zoonotic diseases through a One Health approach compared to working in isolation. An estimated $137 billion in annual benefits could be gained from a