This document discusses the One Health approach, which recognizes the interconnectedness of human, animal, and environmental health. It notes that zoonotic diseases pose a large disease burden, especially in developing countries, and factors like human encroachment on wildlife habitats, intensive farming, and increased travel and trade have contributed to the emergence and spread of diseases. The One Health approach aims to promote cross-sectoral collaboration between medical, veterinary, and environmental professionals to achieve optimal health outcomes. Key organizations promoting One Health include WHO, FAO, OIE, and CDC. While India has started some One Health initiatives, more coordination is still needed between its medical and veterinary colleges to address zoonotic threats.
Presented by Hung Nguyen-Viet and Jakob Zinsstag at a technical workshop of the Food and Agriculture Organization of the United Nations (FAO) regional initiative on One Health, Bangkok, Thailand, 11–13 October 2017.
Antimicrobial Resistance: A One Health Challenge for Joint ActionSIANI
Presented by Juan Lubroth at the seminar "Antimicrobial resistance; linkages between humans, livestock and water in peri-urban areas" at the World Water Week, 29th August 2016.
Presented by Hung Nguyen-Viet and Jakob Zinsstag at a technical workshop of the Food and Agriculture Organization of the United Nations (FAO) regional initiative on One Health, Bangkok, Thailand, 11–13 October 2017.
Antimicrobial Resistance: A One Health Challenge for Joint ActionSIANI
Presented by Juan Lubroth at the seminar "Antimicrobial resistance; linkages between humans, livestock and water in peri-urban areas" at the World Water Week, 29th August 2016.
Brief introduction to the One Health concept, and beyondILRI
Presentation by Alexandre Caron, Hélène de Nys, Alexandre Hobeika and Vladimir Grosbois at the Capacitating One Health in Eastern and Southern Africa (COHESA) partner orientation workshop, 16 December 2021.
One Health approach to address zoonotic and emerging infectious diseases and ...ILRI
Presentation by Hung Nguyen-Viet, Hu Suk Lee, Fred Unger, Arshnee Moodley, Eric Fèvre, Barbara Wieland, Bernard Bett, Michel Dione, Edward Okoth, Johanna Lindahl, Sinh Dang-Xuan and Delia Grace at the virtual 2020 Global ODA Forum for Sustainable Agricultural Development 9–10 November 2020.
One Health – an interdisciplinary approach in combating emerging diseasesILRI
Presentation by Hung Nguyen-Viet, Delia Grace and Jakob Zinsstag at the International Symposium of Health Sciences (iSIHAT 2013), Kuala Lumpur, Malaysia, 20-21 August 2013.
emerging and re-emerging vector borne diseasesAnil kumar
this presentation in about emerging and re-emerging vector borne diseases and their spatial spread with reference to time, surveillance, monitoring and management program and other difficulties and suggestions for program
Presentation made by Zsuzsanna Jakab, WHO Regional Director for Europe, at the meeting "Health in Action reforming the Greek National Health System to Improve Citizens’ Health", on 5 March 2014, Athens, Greece.
Zoonoses (Greek “zoon” = animal) are the diseases or infections that are naturally transmissible from vertebrate animals to humans. This group of infections constitutes significant burdens on global public health. The World Health Organisation (WHO) estimates that 25% of the total 57 million annual deaths that occur globally are caused by microbes with a major proportion occurring in the developing world (Chugh, 2008). Of total identified 1,415 species of infectious organisms known to be pathogenic to humans (including 217 viruses and prions, 538 bacteria and rickettsia, 307 fungi, 66 protozoa and 287 helminths), zoonotic agents constitute 868 (61%), with humans serving as the primary reservoir for only 3% of them. Of the 175 diseases considered to be emerging, 132 (75%) are zoonotic in origin (Taylor et al., 2001). In low income countries, established and emerging zoonoses make up 26 % of the DALYs (Disability-adjusted life year) lost to infectious disease and 10 % of the total DALYs lost. In contrast, in high income countries it represent < 1 % of DALYs lost to infectious disease and only 0.02 % of the total disease burden (Grace et al., 2012).
Vectors are living organisms that can transmit infectious diseases between humans or from animals to humans. Vector-borne diseases are infections transmitted by the bite of infected arthropod species, such as mosquitoes, ticks, triatomine bugs, flies, fleas, sandflies, and blackflies (Confalonieri et al., 2007). Among these mosquitoes are the best known disease transmission vectors for many of the fatal and diseases of economic burden. Vector-borne diseases account for 17% of the estimated global burden of all infectious diseases (CDC, 2014). Every year > 1 billion people are infected and > 1 million people die from vector-borne diseases including malaria, dengue, schistosomiasis, leishmaniasis, yellow fever, lymphatic filariasis, Japanese encephalitis and onchocerciasis. One sixth of the illness and disability suffered worldwide is due to vector-borne diseases with more than half the world’s population currently estimated to be at risk of these diseases. Global trade, rapid international travel, unsustainable urbanization, environmental changes such as climate change and emerging insecticidal and drug resistances, are causing vectors and vector-borne diseases to spread beyond borders (WHO, 2014).
Presentation by Delia Grace at the first United Nations Environment Programme (UNEP) Science-Policy Forum ahead of the Second Session of the United Nations Environment Assembly (UNEA-2), Nairobi, Kenya, 20 May 2016.
Brief introduction to the One Health concept, and beyondILRI
Presentation by Alexandre Caron, Hélène de Nys, Alexandre Hobeika and Vladimir Grosbois at the Capacitating One Health in Eastern and Southern Africa (COHESA) partner orientation workshop, 16 December 2021.
One Health approach to address zoonotic and emerging infectious diseases and ...ILRI
Presentation by Hung Nguyen-Viet, Hu Suk Lee, Fred Unger, Arshnee Moodley, Eric Fèvre, Barbara Wieland, Bernard Bett, Michel Dione, Edward Okoth, Johanna Lindahl, Sinh Dang-Xuan and Delia Grace at the virtual 2020 Global ODA Forum for Sustainable Agricultural Development 9–10 November 2020.
One Health – an interdisciplinary approach in combating emerging diseasesILRI
Presentation by Hung Nguyen-Viet, Delia Grace and Jakob Zinsstag at the International Symposium of Health Sciences (iSIHAT 2013), Kuala Lumpur, Malaysia, 20-21 August 2013.
emerging and re-emerging vector borne diseasesAnil kumar
this presentation in about emerging and re-emerging vector borne diseases and their spatial spread with reference to time, surveillance, monitoring and management program and other difficulties and suggestions for program
Presentation made by Zsuzsanna Jakab, WHO Regional Director for Europe, at the meeting "Health in Action reforming the Greek National Health System to Improve Citizens’ Health", on 5 March 2014, Athens, Greece.
Zoonoses (Greek “zoon” = animal) are the diseases or infections that are naturally transmissible from vertebrate animals to humans. This group of infections constitutes significant burdens on global public health. The World Health Organisation (WHO) estimates that 25% of the total 57 million annual deaths that occur globally are caused by microbes with a major proportion occurring in the developing world (Chugh, 2008). Of total identified 1,415 species of infectious organisms known to be pathogenic to humans (including 217 viruses and prions, 538 bacteria and rickettsia, 307 fungi, 66 protozoa and 287 helminths), zoonotic agents constitute 868 (61%), with humans serving as the primary reservoir for only 3% of them. Of the 175 diseases considered to be emerging, 132 (75%) are zoonotic in origin (Taylor et al., 2001). In low income countries, established and emerging zoonoses make up 26 % of the DALYs (Disability-adjusted life year) lost to infectious disease and 10 % of the total DALYs lost. In contrast, in high income countries it represent < 1 % of DALYs lost to infectious disease and only 0.02 % of the total disease burden (Grace et al., 2012).
Vectors are living organisms that can transmit infectious diseases between humans or from animals to humans. Vector-borne diseases are infections transmitted by the bite of infected arthropod species, such as mosquitoes, ticks, triatomine bugs, flies, fleas, sandflies, and blackflies (Confalonieri et al., 2007). Among these mosquitoes are the best known disease transmission vectors for many of the fatal and diseases of economic burden. Vector-borne diseases account for 17% of the estimated global burden of all infectious diseases (CDC, 2014). Every year > 1 billion people are infected and > 1 million people die from vector-borne diseases including malaria, dengue, schistosomiasis, leishmaniasis, yellow fever, lymphatic filariasis, Japanese encephalitis and onchocerciasis. One sixth of the illness and disability suffered worldwide is due to vector-borne diseases with more than half the world’s population currently estimated to be at risk of these diseases. Global trade, rapid international travel, unsustainable urbanization, environmental changes such as climate change and emerging insecticidal and drug resistances, are causing vectors and vector-borne diseases to spread beyond borders (WHO, 2014).
Presentation by Delia Grace at the first United Nations Environment Programme (UNEP) Science-Policy Forum ahead of the Second Session of the United Nations Environment Assembly (UNEA-2), Nairobi, Kenya, 20 May 2016.
The roles of livestock and farmed wildlife in preventing the next pandemic: C...ILRI
Presentation by Hung Nguyen-Viet, Delia Grace, Bernard Bett, Johanna Lindahl and Dieter Schillinger at a virtual workshop on countering zoonotic spillover of high consequence pathogens, 12 July 2022.
Sanskruti Sawarkar, PPT of Wildlife Trafficking rafficking and Human Health.ppsxSanskruti Sawarkar
It's all about Wildlife trafficking impact on the human health. It shows the case study by wildlife officers and providing awareness about trafficked animals products as well as the importance of legal actions. It also gives the information about various NGO's work done in conversation of wildlife. Some cutting of various pouching activities are involve in it to enhance the objectives.
Mobius Foundation Newsletter July 2020. The Latest newsletter published by Mobius Foundation which is an NGO for Environment and Sustainability & one of the TOP NGO in Delhi
Small ruminant keepers’ knowledge, attitudes and practices towards peste des ...ILRI
Presentation by Guy Ilboudo, Abel Sènabgè Biguezoton, Cheick Abou Kounta Sidibé, Modou Moustapha Lo, Zoë Campbell and Michel Dione at the 6th Peste des Petits Ruminants Global Research and Expertise Networks (PPR-GREN) annual meeting, Bengaluru, India, 28–30 November 2023.
Small ruminant keepers’ knowledge, attitudes and practices towards peste des ...ILRI
Poster by Guy Ilboudo, Abel Sènabgè Biguezoton, Cheick Abou Kounta Sidibé, Modou Moustapha Lo, Zoë Campbell and Michel Dione presented at the 6th Peste des Petits Ruminants Global Research and Expertise Networks (PPR-GREN) annual meeting, Bengaluru, India, 29 November 2023.
A training, certification and marketing scheme for informal dairy vendors in ...ILRI
Presentation by Silvia Alonso, Jef L. Leroy, Emmanuel Muunda, Moira Donahue Angel, Emily Kilonzi, Giordano Palloni, Gideon Kiarie, Paula Dominguez-Salas and Delia Grace at the Micronutrient Forum 6th Global Conference, The Hague, Netherlands, 16 October 2023.
Milk safety and child nutrition impacts of the MoreMilk training, certificati...ILRI
Poster by Silvia Alonso, Emmanuel Muunda, Moira Donahue Angel, Emily Kilonzi, Giordano Palloni, Gideon Kiarie, Paula Dominguez-Salas, Delia Grace and Jef L. Leroy presented at the Micronutrient Forum 6th Global Conference, The Hague, Netherlands, 16 October 2023.
Food safety research in low- and middle-income countriesILRI
Presentation by Hung Nguyen-Viet at the first technical meeting to launch the Food Safety Working Group under the One Health Partnership framework, Hanoi, Vietnam, 28 September 2023
Presentation by Hung Nguyen-Viet at the first technical meeting to launch the Food Safety Working Group under the One Health Partnership framework, Hanoi, Vietnam, 28 September 2023
Reservoirs of pathogenic Leptospira species in UgandaILRI
Presentation by Lordrick Alinaitwe, Martin Wainaina, Salome Dürr, Clovice Kankya, Velma Kivali, James Bugeza, Martin Richter, Kristina Roesel, Annie Cook and Anne Mayer-Scholl at the University of Bern Graduate School for Cellular and Biomedical Sciences Symposium, Bern, Switzerland, 29 June 2023.
Assessing meat microbiological safety and associated handling practices in bu...ILRI
Presentation by Patricia Koech, Winnie Ogutu, Linnet Ochieng, Delia Grace, George Gitao, Lily Bebora, Max Korir, Florence Mutua and Arshnee Moodley at the 8th All Africa Conference on Animal Agriculture, Gaborone, Botswana, 26–29 September 2023.
Ecological factors associated with abundance and distribution of mosquito vec...ILRI
Poster by Max Korir, Joel Lutomiah and Bernard Bett presented the 8th All Africa Conference on Animal Agriculture, Gaborone, Botswana, 26–29 September 2023.
Practices and drivers of antibiotic use in Kenyan smallholder dairy farmsILRI
Poster by Lydiah Kisoo, Dishon M. Muloi, Walter Oguta, Daisy Ronoh, Lynn Kirwa, James Akoko, Eric Fèvre, Arshnee Moodley and Lillian Wambua presented at Tropentag 2023, Berlin, Germany, 20–22 September 2023.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Unveiling the Energy Potential of Marshmallow Deposits.pdf
One World One Health Approach
1. One World One Health Approach
Habibur Rahman and Vijayalakshmy Kennady (ILRI)
Strategy Workshop on Foodborne Diseases, National Academy of Agricultural
Sciences, New Delhi, India, 21 November 2019
Better lives through livestock…………
2. INTRODUCTION
o Human beings, Animals and Plants are
co-existing in the same environment,
o They cannot exist in isolation and
o All are part of a larger communities
Human Health
Animal Health
Environmental Health
Plant Health
3. Impact of animal diseases on human health
Global of Food Animals production is reduced by more than 20% due to
diseases
Even animal diseases not transmissible to human may lead to serious public
health problems due to shortage and deficiencies of Animal Source Food
4. Greatest Burden of Zoonoses falls on One Billion Poor Livestock Keepers (ILRI)
o 2.3 billion cases of human illness with 1.7 million human deaths per year
o More than one in seventh of all livestock per year are infected in poor
countries
Burden of Zoonoses
5. Disease Country Financial Loss
BSE UK
US
Japan
$ 10-13bn
$ 3.5bn
$ 1.5bn
Plaque India $ 2.0bn
Avian Flu Asia
New Zealand
Italy
India
India (Kerala)
$ 5–10bn
$ 500m
$ 400m
Rs. 1,50,000m
Rs. 20 m (Duck outbreak)
SARS China, Hong Kong, Singapore,
Canada
$ 30-50bn
Nipah Malaysia $ 350-400m
Ebola West Africa $ 53.0 bn
Economic Impact of zoonoses
7. Why now... (Factors) As a result…(Impact)
Human populations are growing and
expanding into new geographic
areas
As a result, more people live in close
contact with wild and domestic animals.
Close contact provides more
opportunities for diseases to pass
between animals and people
The earth has experienced changes
in climate and land use, such as
deforestation and intensive farming
practices
Disruptions in environmental conditions
and habitats provide new opportunities
for diseases to pass to animals
International travel and trade have
increased
As a result, diseases can spread quickly
across the globe
Factors that affect Human and Animal Health
Why one health?
8. Definition
One Health is defined as a collaborative, multisectoral, and
transdisciplinary approach — working at the local, regional,
national, and global levels — with the goal of achieving optimal
health outcomes recognizing the interconnection between people,
animals, plants, and their shared environment.
OneHealthisthe collaborative effort of multiple health science
professions,togetherwith their relateddisciplinesandinstitutions –
workinglocally,nationally,andglobally–to attain optimal health for
people,domesticanimals,wildlife, plants,andourenvironment.’
(OneHealthCommission,2011)
One Health concept was officially adopted in 1984
It is a concept to bring together human, animal, and
environmental health.
9. History
Edward Jenner
Rudolf Virchow
Louis Pasteur Robert Koch Theobald Smith
Calvin Schwabe James Harlan Steele
Hippocrates
Demonstrated the
links between
animal and human
health
10. 2004
• Wildlife Conservation Society – One World One Health
• 12 Recommendations – Manhattan Principles
2007
• One Health Approach was recommended by AMA for Pandemic Preparedness
• The AMA collaborated with AVMA & passed the One Health Resolution promoting partnership
between human and veterinary medicine
2008
• FAO, OIE, WHO collaborate with UNICEF, UNSIC and the World Bank to develop joint
strategic framework
2009
• USAID launched the Emerging Pandemic Threats Program
• The One Health Office was established at CDC
2010
• The Tripartite concept published
• UN and World Bank recommended adoption to One Health Approach
2011
• One Health Commission
• The 1st One Health Conference in Africa
• ICOPHAI - Ethiopia
2012 • First One Health Summit
2013-
17
• ICOPHAI - Brazil
• ICOPHAI - Thailand
• ICOPHAI - Qatar
2019 • ICOPHAI - Canada
One World One Health - Events
11. OneWorld, OneHealth-ManhattanPrinciples1. Recognizethe essentiallink between human, domesticanimal andwildlife health and
the threat disease poses
2. Recognizethat decisionsregardingland andwater usehavereal implications forhealth
3. Includewildlife health scienceasanessentialcomponent of global disease
prevention, surveillance, monitoring, control andmitigation
4. Recognizethat public health programs cangreatly contribute to conservationefforts
5. Deviseadaptive,holistic andforward-looking approachesto the prevention,
surveillance,monitoring, control andmitigation of emergingandresurgingdiseasesthat
takethe complexinterconnections amongspeciesinto full account
6. Integrate biodiversity conservationperspectivesandhuman needswhen developing
solutions to infectious diseasethreats
7. Reducedemand for andbetter regulate the international wildlife andbushmeattrade
8. Restrict the massculling of wildlife speciesfor diseasecontrol
9. Increaseinvestment in the global human andanimal healthinfrastructure
10. Formcollaborative relationships amonggovernments,localpeople, andthe private and
publicsectors
11. Provideadequate resourcesandsupport for global wildlife healthsurveillance
12. Invest in educating andraisingawarenessamongthe world'speople
33
OneWorld,OneHealth-ManhattanPrinciples
12. Bush Meat Trade
Wet Markets
Agricultural Encroachment,
and Wildlife Habitat Loss
Increased Human-Animal -Wildlife Interface
13. Land use change
Human encroachment, extractive industries, deforestation,
habitat fragmentation, biodiversity loss, urbanisation
&urban planning
Emergence&Re-emergence
Food and Agricultural systems
Intensifying /expanding farming systems, greater livestock
density, trade networks and globalisation
,unregulated/irregular use of drugs & vaccines, biosecurity
Human Behaviour
Hunting & consumption practices, cultural patterns&
processes, travel capabilities, breakdown of governance,
antimicrobial usage pattern
Environmental systems
Climate change, natural disasters, periodic climate systems
Disease Emergence pathway at Human-Animal Interface
15. Main factors influencing the emergence of animal diseases
according to the period of time
FACTOR 2007 2017 2027
16.
17. Foodborne diseases cost India about $28 billion (Rs1,78,100 crore) or around
0.5% of the country's gross domestic product (GDP) every year
(‘Food for All' partnership of the World Bank Group and The Netherlands)
Foodborne diseases
19. Bioterrorism
o Intentional or deliberate releaseof viruses,
bacteria, or other agentsusedto causeillness or
death in people, animals,orplants
o Ex:
• Anthrax
• Smallpox
• Nipah
• Botulinumtoxin
o Bioterrorism Act of 2002-Accordingto this law,there isan
essential element of national preparednessagainst
bioterrorism andthe focusis on safety of drugs,food, and
water from biologicalagentsandtoxins
o India isyet to havealaw onbioterrorism
Bio-Terrorism
20. Goal - Six Strategies
1. More preventiveactionat the animal–human–ecosystems interface
2. Building more robust public andanimal health systems with ashift
from short term to long-term intervention
3. Strengtheningthe national andinternational emergencyresponse
capabilitiesto prevent andcontroldiseaseoutbreaks
4. Better addressingthe concernsofthepoorbyshifting focusfrom
developedto developing economies
5. Promotinginstitutionalcollaborationacrosssectorsanddisciplines
6. Conductingstrategicresearchto enabletargeted diseasecontrol
programs
22. o Physicians to vaccinate & treat victims
o Veterinarians to vaccinate & sterilize dogs & cats
o Wildlife experts to advise on wild animal reseviours
o Ecologists to tell responsible authorities
o Sanitarians to eliminate garbage that feeds strays
o Educators to teach people to vaccinate their pets
o Media to inform about risks & prevention, e.g. bats
Rabies: A Perfect example of One Health
23. 1. MoU between ICAR – ICMR (AMR, Brucellosis, Biofortified foods)
2. Establishment of National Institute of Zoonoses
3. INFAR – Indian Network of Fish and Animal AMR
4. One Health India Conference 2019
5. IDSP
One Health program in India
24. Missedopportunity• 460medicalcollegesand56veterinary collegesin India, but do have
little or no coordination
• Indian subcontinent isa‘hotspot’ for zoonotic,drug-resistantand vector-
bornepathogens.Butweknowlittle aboutthe keythreats
• Governancestructure andinter-sectorial coordination isalso problematic,
with human,animal andenvironmental healthcontrolled bydifferent
ministries, with little cross-talk
• National Health Policyapprovedrecently buttherenomention of
“zoonoses” and“emerging infectious diseases”
Missedopportunity
25. World Health Organization (WHO)
Food and Agriculture Organization (FAO)
World Organization for Animal Health (OIE)
One Health Initiative
US Centers for Disease Control
EcoHealth Alliance
Organizations working on One Health
26. o Adequate infrastructure and expertise at national and local levels, and at entry
points
o Timely and responsive disease surveillance systems for animal and human
populations
o Up-to-date emergency preparedness and response plans
o Capacity to apply international agreements and standards
o Continuous evaluation and improvement of biosecurity
o Governance and legislation in line with international standards
o Adequate and sustainable laboratory capacity supported by external quality
assurance systems
o Established monitoring and evaluation systems for Veterinary and Public Health
Services
o A communication protocol between animal and public health surveillance
systems
CONCLUSION
27. This presentation is licensed for use under the Creative Commons Attribution 4.0 International Licence.
better lives through livestock
ilri.org