Doppler ultrasound uses the Doppler effect to measure the velocity of moving objects like blood cells. It works by transmitting ultrasound pulses and detecting slight differences in the echoes from moving scatterers compared to stationary tissue. These differences are measured as a Doppler frequency shift, which can be used to calculate velocity if the angle between the ultrasound beam and flow direction is known. Doppler ultrasound provides both spectral Doppler displays of velocity over time at a single point, as well as color flow imaging, which produces color-coded maps of flow direction and velocity superimposed on B-mode images. Factors like velocity, ultrasound frequency, beam-flow angle, and imaging mode affect the quality of Doppler ultrasound images.
An overview of Doppler Effect in Ultrasonography - the medical imaging of the body using Ultrasound.
Includes Colour Doppler, Power Doppler, Spectral Doppler, Continuous Wave Doppler, Pulsed Wave Doppler, and comparisons with other Radiographic imaging modalities.
This concepts of Doppler physics contents are introduction, history, on which principle it works, applications of this physics Doppler angle types of flow types of Doppler advantages disadvantages and summary
An overview of Doppler Effect in Ultrasonography - the medical imaging of the body using Ultrasound.
Includes Colour Doppler, Power Doppler, Spectral Doppler, Continuous Wave Doppler, Pulsed Wave Doppler, and comparisons with other Radiographic imaging modalities.
This concepts of Doppler physics contents are introduction, history, on which principle it works, applications of this physics Doppler angle types of flow types of Doppler advantages disadvantages and summary
This slide contain application of ultrasound and biological effects of ultrasound , ppt contains many GIF files and notes , which may not be accessible here ,,
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
1. DOPPLER US (2)
Dr. Kamal Sayed MSc US UAA
dopp principles/ guidelines/Velocity measurement/
dopp TXR types/aliasing/flow modes
2. •
DOPPPLER US PRINCIPLES & PRACTICE GUIDLINE
•
What is the principle of ultrasound?
•
An electric current passes through a cable to the transducer
and is applied to the crystals, causing them to deform and
vibrate. This vibration produces the ultrasound beam. The
frequency of the ultrasound waves produced is
predetermined by the crystals in the transducer.
3. •
Competent use of Doppler ultrasound techniques requires an
understanding of three key components:
•
(1) The capabilities and limitations of Doppler ultrasound;
(2) The different parameters which contribute to the flow
display;
(3) Blood flow in arteries and veins.
•
This chapter describes how these components contribute to
the quality of Doppler ultrasound images.
•
Guidelines are given on how to obtain good images in all flow
imaging modes.
4. •
Ultrasound images of flow, whether color flow or spectral
Doppler, are essentially obtained from measurements of
movement.
•
In ultrasound scanners, a series of pulses is transmitted to
detect movement of blood.
•
Echoes from stationary tissue are the same from pulse to
pulse.
•
5. •
Echoes from moving scatterers exhibit slight differences in the
time for the signal to be returned to the receiver
•
These differences can be measured as a direct time difference
or, more usually, in terms of a phase shift from which the
‘Doppler frequency’ is obtained
•
They are then processed to produce either a color flow
display or a Doppler sonogram
•
slide (6/7)
•
.
6. Figure 1 Ultrasound velocity measurement. The diagram shows a scatterer S moving at velocity V
with a beam/flow angle q.
The velocity can be calculated by the difference in transmit-to-receive time from the first pulse to
the second (t2), as the scatterer moves through the beam.
7. Figure 2: Doppler ultrasound. Doppler ultrasound measures the movement of the
scatterers through the beam as a phase change in the received signal. The resulting
Doppler frequency can be used to measure velocity if the beam/flow angle is known.
8. •
if the flow is perpendicular to the beam, there is NO relative
motion from pulse to pulse.
•
The size of the Doppler signal is dependent on:
•
(1) Blood velocity: as velocity increases, so does the Doppler
frequency;
(2) Ultrasound frequency: higher ultrasound frequencies give
increased Doppler frequency. (As in B-mode, lower ultrasound
frequencies have better penetration).
(3) The choice of frequency: is a compromise between better
sensitivity to flow or better penetration;
9. •
(4 The angle of insonation: the Doppler frequency increases
as the Doppler ultrasound beam becomes more aligned to the
flow direction (the angle q between the beam and the
direction of flow becomes smaller). This is of the utmost
importance in the use of Doppler ultrasound
•
. The implications are illustrated schematically
in slide (10)
•
10. Effect of the Doppler angle in the sonogram (A) higher-frequency Doppler signal is obtained if the beam is
aligned more to the direction of flow. In the diagram, beam (A) is more ali)gned than (B) and produces higher-
frequency Doppler signals. The beam/flow angle at (C) is almost 90° and there is a very poor Doppler signal.
The flow at (D) is away from the beam and there is a negative signal.
.
11. •
All types of Doppler ultrasound equipment employ filters to
cut out the high amplitude, low-frequency Doppler signals
resulting from tissue movement, for instance due to vessel
wall motion.
•
Filter frequency can usually be altered by the user, for
example, to exclude frequencies below 50, 100 or 200 Hz.
•
This filter frequency limits the minimum flow velocities that
can be measured
12. •
Continuous-wave doppler transducer
•
Continuous wave systems use continuous transmission and
reception of ultrasound.
•
Doppler signals are obtained from all vessels in the path of
the ultrasound beam (until the ultrasound beam becomes
sufficiently attenuated due to depth).
•
Continuous wave Doppler ultrasound is unable to determine
the specific location of velocities within the beam and cannot
be used to produce color flow images.
•
13. •
Relatively inexpensive Doppler ultrasound systems are
available which employ continuous wave probes to give
Doppler output without the addition of B-mode images.
•
Continuous wave Doppler is also used in adult cardiac
scanners to investigate the high velocities in the aorta.
•
Slide (14)
15. •
Pulsed-wave doppler transducer
•
Doppler ultrasound in general and obstetric ultrasound
scanners uses pulsed wave ultrasound.
•
This allows measurement of the depth (or range) of the flow
site.
•
Additionally, the size of the sample volume (or range gate) can
be changed.
•
Pulsed wave ultrasound is used to provide data for Doppler
sonograms and color flow images
•
Slide (16).
•
17. •
ULTRASOUND FLOW MODES
•
Since color flow imaging provides a limited amount of
information over a large region, and spectral Doppler provides
more detailed information about a small region, the two
modes are complementary and, in practice, are used as such.
•
CFD can be used to : 1/ identify blood vessels requiring
examination, 1/ identify the presence and direction of flow,
•
3/ to highlight gross circulation anomalies, throughout the
entire color flow image, 4/ and to provide beam/vessel angle
correction for velocity measurements. .
•
18. •
Pulsed wave Doppler is used to provide analysis of the flow at
specific sites in the vessel under investigation.
•
When using color flow imaging with pulsed wave Doppler, the
color flow/B-mode image is frozen while the pulsed wave
Doppler is activated.
•
Recently, some manufacturers have produced concurrent
color flow imaging and pulsed wave Doppler, sometimes
referred to as triplex scanning
19. •
when these modes are used simultaneously, the performance
of each is decreased.
•
Because transducer elements are employed in three modes
(B-mode, color flow and pulsed wave Doppler):,
•
@ The frame rate is decreased,
•
@ The color flow box is reduced in size
•
@ and the available pulse repetition frequency is reduced,
leading to increased susceptibility to aliasing.
20. •
•
The magnitude of the color flow output is displayed rather
than the Doppler frequency signal.
•
Power Doppler does not display flow direction or different
velocities.
•
It is often used in conjunction with frame averaging to
increase sensitivity to low flows and velocities. It
complements the other two modes. Hybrid color flow modes
incorporating power and velocity data are also available from
some manufacturers. .
•
21. •
Power Doppler is also referred to as energy Doppler,
amplitude Doppler and Doppler angiography.
•
These can also have improved sensitivity to low flow.
•
A brief summary of factors influencing the displays in each
mode is given in the following sections.
•
Most of these factors are set up approximately for a particular
mode when the application (e.g. fetal scan) is chosen,
although the operator will usually alter many of the controls
during the scan to optimize the image
22. •
Spectral Doppler
•
1- Examines flow at one site
•
2- Detailed analysis of distribution of flow
•
3- Good temporal resolution – can examine flow waveform
•
4- Allows calculations of velocity and indices
23. •
Color flow
•
1- Overall view of flow in a region
•
2- Limited flow information
•
3- Poor temporal resolution/flow dynamics (frame rate can be
low when scanning deep)
•
4- color flow map (diferent color maps)
•
5- direction information
•
6- velocity information (high velocity & low velocity)
•
7- turbulent flows
26. "Color Power Angio" of a submucosus fibroid, note the small vessels inside
the tumor.
27. •
Color flow imaging (Color flow Doppler) ultrasound produces
a color-coded map of Doppler shifts superimposed onto a B-
mode ultrasound image (Color Flow Maps).
•
Although color flow imaging uses pulsed wave ultrasound, its
processing differs from that used to provide the Doppler
sonogram.
•
28. •
Color flow imaging may have to produce several thousand
color points of flow information for each frame superimposed
on the B-mode image. Color flow imaging uses fewer, shorter
pulses along each color scan line of the image to give a mean
frequency shift and a variance at each small area of
measurement. This frequency shift is displayed as a color
pixel.
29. •
The scanner then repeats this for several lines to build up the
color image, which is superimposed onto the B-mode image.
The transducer elements are switched rapidly between B-
mode and color flow imaging to give an impression of a
combined simultaneous image.
•
The pulses used for color flow imaging are typically three to
four times longer than those for the B-mode image, with a
corresponding loss of axial resolution.
30. •
Assignment of color to frequency shifts is usually based on
@direction (for example, red for Doppler shifts towards the
ultrasound beam and blue for shifts away from it) and
@magnitude : a) different color hues b) or lighter saturation
for higher frequency shifts).
•
The color Doppler image is dependent on general Doppler
factors, particularly the need for a good beam/flow angle.
31. •
. Curvilinear and phased array transducers have a radiating
pattern of ultrasound beams that can produce complex color
flow images, depending on the orientation of the arteries and
veins. In practice, the experienced operator alters the
scanning approach to obtain good insonation angles so as to
achieve unambiguous flow images.