Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease carried by Hyalomma ticks and transmitted to humans via tick bites or contact with infected animal blood. The virus is endemic in Africa, the Middle East, Asia, and the Balkans. It causes severe hemorrhagic fever in humans with flu-like symptoms initially, which can develop into vomiting blood, black stools, liver swelling, and shock. The disease has a high fatality rate of around 30% and is diagnosed through blood tests and tissue sampling. There is no vaccine available though supportive care and ribavirin treatment may help recovery. Prevention involves avoiding tick bites and reducing contact with potentially infected
The lecture gives concise review about the main four groups of viruses causing hemorrhagic fever i.e. Flavivirues, Filoviruses, Arenaviruses and Bunyaviruses.
this is a very serious hemorrhagic virus even if, it is very rare in our settings , we should be aware of it and sometime include it in our differential of renal failure with hemorrhagic fever or cardiopulmonary stuffs.
This presentation provides all up-to-date information regarding the Crimean-Congo Hemorrhagic Fever (CCHF), which is the hot topic of medical field in Pakistan nowadays.
The lecture gives concise review about the main four groups of viruses causing hemorrhagic fever i.e. Flavivirues, Filoviruses, Arenaviruses and Bunyaviruses.
this is a very serious hemorrhagic virus even if, it is very rare in our settings , we should be aware of it and sometime include it in our differential of renal failure with hemorrhagic fever or cardiopulmonary stuffs.
This presentation provides all up-to-date information regarding the Crimean-Congo Hemorrhagic Fever (CCHF), which is the hot topic of medical field in Pakistan nowadays.
Kyasanur forest disease, KFD is a febrile disease associated with haemorrhage caused by kyasanur forest disease virus, a member of virus family of arbovirus & flavivirus and transmitted to man by bite of infected ticks.
This ppt is About Rabies epidemiology and treatment .
This is done by using Park book 24th edition of PSM .
This presentation is presented in academics of Master of public health in Christian medical college .
One more Important thing is that that zareb regime (intramuscular ) is not practiced . We try to make this ppt lucid. and the statistics is used in the presentation is upto 27 june 2018
Measles is a highly contagious viral infection.
It is exanthematous disease with fewer, cough, coryza (rhinitis) and conjunctivitis.
Before the widespread use of measles vaccines, it was estimated that measles caused between 5 million and 8 million deaths worldwide each year.
Kyasanur forest disease, KFD is a febrile disease associated with haemorrhage caused by kyasanur forest disease virus, a member of virus family of arbovirus & flavivirus and transmitted to man by bite of infected ticks.
This ppt is About Rabies epidemiology and treatment .
This is done by using Park book 24th edition of PSM .
This presentation is presented in academics of Master of public health in Christian medical college .
One more Important thing is that that zareb regime (intramuscular ) is not practiced . We try to make this ppt lucid. and the statistics is used in the presentation is upto 27 june 2018
Measles is a highly contagious viral infection.
It is exanthematous disease with fewer, cough, coryza (rhinitis) and conjunctivitis.
Before the widespread use of measles vaccines, it was estimated that measles caused between 5 million and 8 million deaths worldwide each year.
Between 1885 and 1908, King Leopold II’s imperialistic endeavors led to the rape, torture, mutilation, enslavement, and murder of over ten million Congolese people. The discovery of these atrocities by humanitarian activists and their determination to stop crimes committed by Leopold’s African explorers and Congo Free State officials led to the creation of the first universal human rights movement that was based upon the concept of “crimes against humanity.”
Decreto Presidencial 154/16, publicado em 05 de Agosto de 2016. Complementar à Lei Geral do Trabalho 7/15 e estabelece o regime de multas às contravenções à Legislação trabalhista vigente.
Para receber esta e outras Legislações em Vigor, ou antigas, entre em contacto: admin@grupomieres.com. Também dispomos das Legislações em Inglês.
www.grupomieres.com
In this presentation you will find about the zoonotic potential of rabies virus, its impact in terms of DALYs.
Epidemiology and geographical distribution of rabies.
You will learn about the reservoir and source of rabies, transmission of rabies virus.
You will also learn about the virology of rabies virus inculding its family, genus, its structure, its different protein and the replication cycle of rabies virus.
It will also put light on the pathogenesis of rabies virus and different stages of rabies virus infection.
Then it will discuss about the laboratory diagnosis of rabies virus infection in humans as well as in animals including specimen collection, culturing, microscopy, animal inoculation and molecular diagnosis.
After that, you will get information about the prevention and control of rabies and different successful control strategies adopted by several countries of the world.
In the end it will discuss the status of rabies in Pakistan and specially WHO responses to rabies control in pakistan.
Invasion of the skin or mucous membranes by a pathogenic organism or parasite.
Infection in which entrance of the pathogenic organism (or the parasite) occurs through the skin or mucus membranes.
Some infectious agents can invade the intact (undamaged) skin or mucous membranes, but the majority needs injured surfaces in the form of abrasions, scratches, wounds or ulcers.
SARS stands for severe acute respiratory syndrome . caused by a corona virus . major outbreak in south china in 2002 with fatality of about 10% and 800 deaths in a single outbreak.
Just a short update to bring awareness to health care professionals of the monkeypox virus dilemma in 2022,and to inform professionals in Nigeria to be alert as to make diagnosis and inform appropriate authorities. Also, to alert of some of the impediments we face in the undeveloped world in measures against viral infections.
Arthropods form a major group of disease vectors with mosquitoes, flies, sand flies, lice, fleas, ticks and mites transmitting a huge number of diseases.
Course of NEET SS preparation is limitless. I always advise all my juniors to decide their one year preparation schedule on the first day of the study.
My name is Dr. Mayur Patel. I am providing you the list of books and what topics I have read from those books while preparing for NEET SS 2020. You should have your own plan of study and this may help you a little.
Intercostal drainage tube insertion is an emergency as well as planned procedure. In emergency it is a one of the life saving procedures. That's why it is important to learn the anatomy and physiology behind insertion of ICD and what should be the ideal procedure and post procedure care.
Cerebellum is the organ that controls tone of muscle and maintains balance of body. It is also responsible for co-ordination of the movements. There are some signs which suggest the abnormalities in Cerebellar functioning.
Different type of Energy Sources used in Surgery are described In this presentation...
like Radio frequency Electro-surgery
Ultrasound Energy
Laser
Argon beam Coagulation
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
2. Introduction
• Crimean–Congo hemorrhagic fever (CCHF) is a
widespread tick-borne viral disease that is endemic in Africa,
the Balkans, the Middle East and Asia.
• The virus is a member of the Bunyaviridae family of RNA
viruses.
• It is a zoonotic disease carried by several domestic and wild
animals.
3. Epidemiology
Primary Host : It is a zoonotic disease carried by several
domestic and wild animals.
Transmission : By Hyalomma tick
Human : Infected by Tick bite
4. Epidemiology
• Crimean–Congo hemorrhagic fever occurs most frequently
among agricultural workers following the bite of an infected
tick
• Crimean hemorrhagic fever, first isolated in Crimea in 1945.
• Identical Congo fever was first isolated in Congo in 1956.
That’s why name given as Crimean-Congo fever.
5. Epidemiology
• First Case in Gujarat : In
January 2011, the disease
was reported in Sanand,
Gujarat, India, with 4
reported deaths, which
consisted of the patient
along with the doctor and
the nurse who treated the
patient.
6. We have to discuss about…..
• Agent
• Vector
• Host
8. Congo-Fever
Group :Group V (negative ssRNA)
Order :Unassigned
Family :Bunyaviridae
Genus :Nairovirus
Species :Crimean-Congo hemorrhagic fever virus
10. Bunya virus
• Bunyaviridae is a family of negative-stranded, enveloped RNA
viruses. Though generally found in arthropods or rodents
• Bunyaviridae are vector-borne viruses. transmission occurs
via an arthropod vector (mosquitos, tick, or sandfly).
exception : Hantaviruses
Hantaviruses are transmitted through contact with
deer mice feces.
11.
12. Hard Tick
• Ixodid (hard) ticks, especially those of the genus – Hyalomma,
are both a reservoir and a vector for the CCHF virus.
• Numerous wild and domestic animals, such as cattle, goats,
sheep and hares, serve as amplifying hosts for the virus.
13. Transmission
• Transmission to humans occurs through contact with infected
ticks or animal blood.
• CCHF can be transmitted from one infected human to another
by contact with infectious blood or body fluids.
• Documented spread of CCHF has also occurred in hospitals
due to improper sterilization of medical equipment, reuse of
injection needles, and contamination of medical supplies.
16. Clinical Features
Incubation period - 1–3 day.
Following a tick bite (5–6 days after exposure to infected blood
or tissues), flu-like symptoms appear, which may resolve after
one week.
In up to 75% of cases, however, signs of hemorrhage appear
within 3–5 days of the onset of illness.
Throat petechiae, then soon nosebleeds, and vomiting, and
black stools.
17. Clinical Features
Liver : swollen and painful.
DIC
acute kidney failure and shock,
sometimes acute respiratory
distress syndrome.
Patients usually begin to show
signs of recovery after 9–10
days from when the symptoms
appear, however 30% of the
cases result in death on the
second week of the illness.
18.
19. Diagnosis
• Antigen-capture enzyme-linked immunosorbent assay (ELISA),
• real time polymerase chain reaction (RT-PCR),
• virus isolation attempts, and
• detection of antibody by ELISA (IgG and IgM).
20. Diagnosis
• Laboratory diagnosis of a patient with a clinical history
compatible with CCHF can be made during the acute phase of
the disease by using the combination of detection of the viral
antigen (ELISA antigen capture), viral RNA sequence (RT-
PCR) in the blood or in tissues collected from a fatal case and
virus isolation.
• Immunohistochemical staining can also show evidence of viral
antigen in formalin-fixed tissues.
21. Treatment
• Treatment is primarily symptomatic and supportive, as there
is no established specific treatment.
• Supportive Therapy :
1. fluid balance and correction of electrolyte
abnormalities,
2. oxygenation and hemodynamic support, and
3. appropriate treatment of secondary infections.
• Ribavirin is effective in vitro and has been used during
outbreaks, but there is no trial evidence to support its use.
22. Prevention
• Mouse-brain derived vaccine : The only available and
probably somewhat efficacious CCHF vaccine is an inactivated
antigen preparation currently used in Bulgaria.
• In 2011, a Turkish research team led by Erciyes University has
successfully developed the first non-toxic preventive vaccine,
which passed clinical trials. The vaccine is pending approval
by the FDA.