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• It is a packaged and organized
structure containing most of the DNA
of a living organism
• They can be visible during the cell
division
• It is a region of the chromosome that
joins sister chromatids
• Usually located in the Center part of
the chromosome
• The primary function of the
centromere is to serve as a place of
attachment for spindle fibers during
cell division.
• It is a basic unit of DNA packaging in
Eukaryotes
• Forms the fundamental repeating
units of Eukaryotic Chromatin
• Folded through a series of
successively high order structures to
eventually form a chromosome
• Its core particle consists of
approximately 147 base pairs of DNA
• These are highly alkaline proteins
found in eukaryotic cell that package
and order the DNA structural units
called nucleosomes
• Chief protein components of
Chromatin
• Discovered by Albrecht Kossel in
1884
• Acts as spools around which DNA
• H1 Histone
• It sits in the top of the structure
• Binds the linker DNA region between
nucleosomes
• A complex of macromolecules found in
cells
• Consists of DNA, RNA and Protein
• Only present in Eukaryotic Cells
• It packages DNA into a smaller volume to
fit in the cell
• It protects the DNA from damages
• It controls DNA replication and gene
expression
• It is a one copy of a newly copied
chromosome which is still joined to
the other copy by a single centromere
• Genetically identical
• Humans have 46 chromosomes
Autosomal Chromosomes – 22
pairs of Chromosomes. Usually
labelled with leters
Allosome Chrosomes – Sex
Chromosomes; made up of the last
pair of chromosomes that makes up
the 46 chromosomes in Human
• Largest human chromosomes
• Humans have two copies of
Chromosome #1
• Predicted that it has 4,300 genes
• Represents the 9% of the total DNA in
human cells
Some of the diseases related to this
chromosome:
• Alzheimer Disease
• Breast Cancer
• Microcephaly
• Parkinson Disease
Chromosomes

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Chromosomes

  • 1.
  • 2. • It is a packaged and organized structure containing most of the DNA of a living organism • They can be visible during the cell division
  • 3.
  • 4. • It is a region of the chromosome that joins sister chromatids • Usually located in the Center part of the chromosome • The primary function of the centromere is to serve as a place of attachment for spindle fibers during cell division.
  • 5.
  • 6. • It is a basic unit of DNA packaging in Eukaryotes • Forms the fundamental repeating units of Eukaryotic Chromatin • Folded through a series of successively high order structures to eventually form a chromosome
  • 7. • Its core particle consists of approximately 147 base pairs of DNA
  • 8.
  • 9. • These are highly alkaline proteins found in eukaryotic cell that package and order the DNA structural units called nucleosomes • Chief protein components of Chromatin • Discovered by Albrecht Kossel in 1884 • Acts as spools around which DNA
  • 10.
  • 11.
  • 12. • H1 Histone • It sits in the top of the structure • Binds the linker DNA region between nucleosomes
  • 13.
  • 14. • A complex of macromolecules found in cells • Consists of DNA, RNA and Protein • Only present in Eukaryotic Cells • It packages DNA into a smaller volume to fit in the cell • It protects the DNA from damages • It controls DNA replication and gene expression
  • 15.
  • 16.
  • 17.
  • 18.
  • 19. • It is a one copy of a newly copied chromosome which is still joined to the other copy by a single centromere • Genetically identical
  • 20.
  • 21. • Humans have 46 chromosomes Autosomal Chromosomes – 22 pairs of Chromosomes. Usually labelled with leters Allosome Chrosomes – Sex Chromosomes; made up of the last pair of chromosomes that makes up the 46 chromosomes in Human
  • 22.
  • 23. • Largest human chromosomes • Humans have two copies of Chromosome #1 • Predicted that it has 4,300 genes • Represents the 9% of the total DNA in human cells
  • 24. Some of the diseases related to this chromosome: • Alzheimer Disease • Breast Cancer • Microcephaly • Parkinson Disease