Cholesterol is a fatty substance in the blood that is needed for the body's functions but can accumulate and cause health issues. There are two main types - LDL (bad) cholesterol which raises the risk for heart disease when levels are too high, and HDL (good) cholesterol which helps remove LDL from arteries. Cholesterol levels are affected by diet, physical activity, smoking, and genetics. Maintaining optimal total cholesterol under 200 mg/dL, LDL under 100 mg/dL, and HDL over 60 mg/dL can help lower heart disease risk.