Human Patient Simulation involves using lifelike mannequins controlled by computer software to simulate real-world clinical scenarios. It allows nursing students to develop skills like critical thinking and clinical judgment in a safe environment before interacting with real patients. Various conceptual frameworks guide its use, emphasizing that learning is enhanced when content is just beyond students' current knowledge. While simulations require resources, they can effectively complement clinical placements by replicating experiences not otherwise available and allowing students to reflect on their performance. Potential issues involve ensuring simulations transfer to real-world skills and preventing overgeneralization.