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PREPARED BY
Prof. ASHISH N. UMALE
M. PHARM IN PHARMACOLOGY
ASSISTANT PROFESSOR
SHRADDHA INSTITUTE OF PHARMACY, WASHIM-444505
HUMAN ANATOMY AND
PHYSIOLOGY - I
The Human Eye (Vision
Structure (The Three Tunics)
Fibrous Layer (Outer): Consists of the Sclera (white of the eye,
provides shape) and the Cornea (transparent window that refracts
light).
Vascular Layer (Middle/Uvea):
Choroid: Highly vascularized, prevents light reflection.
Ciliary Body: Secretes aqueous humor and controls lens shape.
Iris: Colored part; regulates pupil size.
Neural Layer (Inner): The Retina contains photoreceptors:
Rods: Responsible for twilight (scotopic) vision.
Cones: Responsible for daylight (photopic) and color vision.
Functions
Refraction: Bending light to focus on the retina.
Accommodation: Adjusting lens curvature for near/far objects.
Transduction: Converting light energy into electrical nerve impulses.
Disorders of the Eye
Myopia (Nearsightedness): Eyeball is too long; light focuses in front of the
retina.
Hypermetropia (Farsightedness): Eyeball is too short; light focuses behind
the retina.
Cataract: Clouding of the crystalline lens, often due to protein denaturation
(aging).
Glaucoma: Increased Intraocular Pressure (IOP) due to blockage of
Aqueous Humor drainage (Canal of Schlemm), leading to optic nerve damage.
Conjunctivitis: "Pink eye"; inflammation (viral, bacterial, or allergic).
The Human Ear
Structure
External Ear: Pinna (Auricle) and External Auditory Canal;
ends at the Tympanic Membrane (eardrum).
Middle Ear: Air-filled cavity containing three ossicles:
Malleus (Hammer), Incus (Anvil), and Stapes (Stirrup).
Connected to the pharynx via the Eustachian tube.
Internal Ear (Labyrinth):
Cochlea: Contains the Organ of Corti (receptors for
hearing).
Semicircular Canals & Vestibule: Receptors for balance
and equilibrium.
Functions
Hearing: Transmission of sound vibrations to electrical signals.
Balance: Maintenance of static and dynamic equilibrium.
Disorders of the Ear
Otitis Media: Inflammation of the middle ear, common in children.
Tinnitus: Constant ringing or buzzing sensation in the ears.
Meniere’s Disease: Inner ear disorder affecting both hearing and
balance (vertigo).
Deafness:
Conductive: Blockage in outer/middle ear (e.g., wax, ossicle
damage).
Sensorineural: Damage to the cochlea or auditory nerve (CN
VIII).
The Nose
Structure
Olfactory Epithelium: Located in the roof of the nasal cavity.
Olfactory Receptors: Bipolar neurons with "olfactory hairs" (cilia) that
detect dissolved chemicals (odorants).
Olfactory Bulb: Where signals are processed before traveling via the
Olfactory Nerve (CN I) to the brain.
Functions
Olfaction: Detection of smell.
Respiratory Support: Filtering, warming, and moistening inhaled air.
Disorders
Anosmia: Total loss of sense of smell (can be due to head injury or
infection).
Rhinitis: Inflammation of the nasal mucosa (allergies/colds).
Nasal Polyps: Non-cancerous growths blocking the airway.
The Tongue
Structure
Papillae: Projections on the tongue (Vallate, Fungiform, Foliate).
Taste Buds: Contain gustatory cells with "taste hairs" protruding through a
taste pore.
Five Primary Tastes: Sweet, Sour, Salty, Bitter, and Umami (savory).
Functions
Gustation: Sensing taste.
Mastication: Assisting in chewing and bolus formation.
Deglutition: Swallowing.
Disorders
Ageusia: Loss of taste function.
Glossitis: Inflammation/swelling of the tongue.
Oral Candidiasis (Thrush): Fungal infection (Candida albicans) creating
white patches.
special senses-eye, ear, nose, tongue.pptx