The document discusses Campylobacter and Helicobacter bacteria, including how Campylobacter can cause food poisoning and Guillain-Barré syndrome, and how Helicobacter pylori was discovered to be a cause of peptic ulcers and gastritis. It provides details on the characteristics, diagnosis, treatment, and prevalence of H. pylori infections, and notes that Robin Warren and Barry Marshall received the Nobel Prize for their research showing H. pylori's role in peptic ulcer disease.
Cholera is a serious bacterial disease that usually
causes severe diarrhea and dehydration. The disease is typically spread through contaminated water.
Modern sewage and water treatment have effectively eliminated cholera in most countries. It’s still a problem in countries like Asia, America and Africa. Mostly in India.
Countries affected by war, poverty, and natural disasters have the greatest risk for a cholera outbreak.
Taxonomy:
class : Gamma Proteobacteria
Order: Vibrionales
Family: Vibrionaceae
Genus: Vibrio
Species: v.cholerae, v.parahaemolyticus,
v. vulnificus, v. alginolyticus
MORPHOLOGY:
Gram negative, actively motile, short, rigid curved bacilli
Resembling letter “V”
about 34 genus
most common in water
1.5µ X 0.2 -0.4 µ in size
polar flagellum , strongly aerobic
Smear – fish in stream appearance
PATHOGENESIS:
Source: Ingestion of contaminated water, food,
fruits and vegetables etc.,
Incubation periods: 1-5 days
Symptoms: Watery diarrhoea, vomiting, thirst, dehydration, muscle cramps
Complications: muscular pain, renal failure, pulmonary edema, cardiac arrhythrnias
DIAGNOSIS:
Specimen: stool sample, water sample(envt)
Microscopy: a) Hanging drop : +ve
b) Gram stain :-ve
Culture: Mac conkey Agar :colourless to light pink
TCBS : yellow colonies
Serology: serological tests are no diagnostic value
TREATMENT:
Adequate replacement of fluids and electrolytes.
Oral tetracycline reduces the period of vibrio excreation.
PREVENTION:
Drink and use bottled water
Frequent washing
Sanitary environment
Defecate in water
Cook food thoroughly
Haemophilus is the name of a group of bacteria. There are several types of Haemophilus. They can cause different types of illnesses involving breathing, bones and joints, and the nervous system. One common type, Hib (Haemophilus influenzae type b), causes serious disease. It usually strikes children under 5 years old
Cholera is a serious bacterial disease that usually
causes severe diarrhea and dehydration. The disease is typically spread through contaminated water.
Modern sewage and water treatment have effectively eliminated cholera in most countries. It’s still a problem in countries like Asia, America and Africa. Mostly in India.
Countries affected by war, poverty, and natural disasters have the greatest risk for a cholera outbreak.
Taxonomy:
class : Gamma Proteobacteria
Order: Vibrionales
Family: Vibrionaceae
Genus: Vibrio
Species: v.cholerae, v.parahaemolyticus,
v. vulnificus, v. alginolyticus
MORPHOLOGY:
Gram negative, actively motile, short, rigid curved bacilli
Resembling letter “V”
about 34 genus
most common in water
1.5µ X 0.2 -0.4 µ in size
polar flagellum , strongly aerobic
Smear – fish in stream appearance
PATHOGENESIS:
Source: Ingestion of contaminated water, food,
fruits and vegetables etc.,
Incubation periods: 1-5 days
Symptoms: Watery diarrhoea, vomiting, thirst, dehydration, muscle cramps
Complications: muscular pain, renal failure, pulmonary edema, cardiac arrhythrnias
DIAGNOSIS:
Specimen: stool sample, water sample(envt)
Microscopy: a) Hanging drop : +ve
b) Gram stain :-ve
Culture: Mac conkey Agar :colourless to light pink
TCBS : yellow colonies
Serology: serological tests are no diagnostic value
TREATMENT:
Adequate replacement of fluids and electrolytes.
Oral tetracycline reduces the period of vibrio excreation.
PREVENTION:
Drink and use bottled water
Frequent washing
Sanitary environment
Defecate in water
Cook food thoroughly
Haemophilus is the name of a group of bacteria. There are several types of Haemophilus. They can cause different types of illnesses involving breathing, bones and joints, and the nervous system. One common type, Hib (Haemophilus influenzae type b), causes serious disease. It usually strikes children under 5 years old
Vibrio cholera with other vibrio species are described in thispresentation along with their biochemical properties and laboratory diagnosis, A short slide on halophilic vibrios is also added
Gram positive aerobic spore forming organisms, primarily a zoonotic disease responsible to cause deadliest infections in humans due to inhalation, ingestion of spores of these organisms present in dust, animal wool, or in dead animals. Causes Cutaneous, Pulmonary and Intestinal Anthrax.
Grow well on ordinary media. Detected by M'Fadyean's Reaction.
Vibrio cholera with other vibrio species are described in thispresentation along with their biochemical properties and laboratory diagnosis, A short slide on halophilic vibrios is also added
Gram positive aerobic spore forming organisms, primarily a zoonotic disease responsible to cause deadliest infections in humans due to inhalation, ingestion of spores of these organisms present in dust, animal wool, or in dead animals. Causes Cutaneous, Pulmonary and Intestinal Anthrax.
Grow well on ordinary media. Detected by M'Fadyean's Reaction.
Morphology and structure of H. pylori
Diagnosis of H. pylori infection
Transmission of H. pylori
Symptoms of H. pylori infection
Treatment and prevention
Pathogenesis of H. pylori
Helicobacter Pylori infect more than 50% of worlds population.HP causes gastritis,PUD,gastric cancer and MALT lymphoma.Variable invasive and noninvasive diagnostic modilities are available.Eradication of H.Pylori is possible with proper therapy.
Helicobactor pylori,gram negative ,fastidious bacteria,important cause for Gastritis as well as gastric carcinoma.Early diagnosis and treatment are necessary to prevent carcinoma.
I am Tariq Bin Aziz, From Southeast University, Bangladesh. I made this presentation on E.coli. I think you will be benefited by my presentation. Thanks All.
Helicobacter & campylobacter lec.11 dr.ihsan alsaimarydr.Ihsan alsaimary
prof . dr. ihsan edan alsaimary
department of microbiology - college of medicine - university of basrah - basrah -IRAQ
ihsanalsaimary@gmail.com
00964 7801410838
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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8. •Food poisoning caused by Campylobacter species can be
debilitating, rarely life-threatening.
Linked with subsequent development of
Guillain- Barré syndrome (GBS), usually developing two to
three weeks after the initial illness.
•Contaminated drinking water and unpasteurized
milk provide an efficient means for distribution.
Contaminated food is a major source of isolated
infections, with incorrectly prepared meat and
poultry are normally the source of the bacteria.
Culture : Skirrow's medium is blood agar infused
with a cocktail of antibiotics: vancomycin, and
trimethoprim under microaerophilic conditions at
42 degrees.
9. Helicobacter pylori
• Bacterial characteristics:
• Morphology: Gram-negative, aerobic or
microaerophilic, spiral-shaped bacilli.
Motile with Flagella .
• Closely related to Helicobacter are species of the
genera Aquaspirillum, Azospirillum, Spirillum, and
Camplyobacter.
10. • In 1875, German scientists found helical shaped
bacteria in lining of the human stomach. The
bacteria could not be grown in culture and results
forgotten.
• The bacterium was rediscovered in 1979 by
Australian pathologist Robin Warren, who did
further research on it with Barry Marshall beginning
in 1981; they isolated the organisms from mucosal
specimens from human stomachs and the first to
successfully culture them. In their original paper,
Warren and Marshall contended that most stomach
ulcers and gastritis were caused by infection by this
bacterium and not by stress or spicy food as had
been assumed before.
11. • Medical community slow to recognize role of this bacterium in
stomach ulcers and gastritis, believing that no microorganism could
survive for long in the acidic environment of the stomach.
• Realization after further studies ,
Marshall drank a Petri dish of H. pylori, developed gastritis, bacteria
were recovered from his stomach lining, thereby satisfying three
out of the four Koch's postulates. The fourth satisfied after second
endoscopy ten days after revealed signs of gastritis and the
presence of "H. pylori".
• Marshall able to treat himself using a fourteen day dual therapy
with bismuth salts and metronidazole. Marshall and Warren went
on to show that antibiotics are effective in the treatment of many
cases of gastritis
• In 2005, Warren and Marshall were awarded the Nobel Prize in
Medicine for their work on H. pylori.
12. Saturday, August 2, 1997
Smug as a bug
• He was so sure he was right and conventional
medical wisdom wrong about the cause of
stomach ulcers that he swallowed bacteria to
prove his point. Now once-skeptical peers are
talking about a possible Nobel prize. MELISSA
SWEET reports.
18. • Genetics :
Helicobacter pylori many strains of H . pylori
which are distinguished by the human
disease with which they are associated.
• Habitat:
Helicobacter pylori lives in interface between
the surface of gastric epithelial cells and the
overlying mucus gel.
Also in the gastric epithelium in the
duodenum and esophagus.
19.
20.
21. • 1983 that H. pylori was recognized
as having any medical importance.
• Now, it has been proven that H.
pylori infection is the main cause of
chronic superficial gastritis
associated with both gastric and
duodenal ulcers.
22. Human Disease.
• Peptic ulcer disease: An ulcer is now known to
be the result of an imbalance between
aggressive and defensive mechanisms in the
stomach and duodenum. Part of that imbalance
can be attributed to infection by H. pylori.
Humans only known host of
Helicobacter pylori.
23. Prevalence :
• In healthy people increases with age to over 50% in
people over the age of 60 in the west.
• In Asia 90-100%
• Blacks more susceptible to infection than Whites,
24.
25. Incidence:
• Increases with decreasing socioeconomic
status.
• Evidence of H. pylori infection in families,
prisons, and nursing homes suggest that H.
pylori is spread by close personal contact.
• Drinking water main source in
underdeveloped countries.
26.
27. • Helicobacter pylori infection usually persist
for life
• H. pylori produces urease …formation of
ammonia… pH increases.
• Cytotoxins, Toxic proteins, Platelet AF and
Lipopolysaccharides.
28. Immune Response
• Activation of neutrophils, monocytes and
macrophages, and the production of serum
antibody IgG and secretory antibody IgA.
• T cells proliferate as in a cell mediated
response.
29.
30. DISEASES
• 1. Chronic superficial gastritis, which is an
inflammation of the stomach lining due to the
infiltration of lymphocytes, plasma cells,
eosinophils, and monocytes into the mucosal
lining of the stomach, which causes injury to the
gastric glands.
• 2.The immune response can also cause
inflammation of the duodenum, leading to
duodenal ulcers.
• 3. Atrophic gastritis, which is a nonspecific
inflammation of the entire lining of the stomach,
may be the result of the infiltration of
lymphocytes into the stomach.
• 4. MALT-type and other lymphomas
31. Diagnosis of H. pylori Infection
Invasive techniques:
• Culture. Because of fastidious nature of H. pylori,
Culturing tedious and is no more sensitive or specific than
simple Histologic analyses. Culturing H. pylori also
involves the cost of endoscopy, making the method even
less practical.
• Histologic analysis of biopsy. Routine Histologic
analysis of biopsy samples is common and practical.
Helpful also to visualize the mucosa, permitting detection
of Histologic gastritis and lesions such as MALT-type
lymphomas.
Requires endoscopy, diagnosis days after the procedure.
32.
33. Campylobacter-like organism (CLO) test.
• This test is based on the fact that mucosal biopsy
specimens inoculated into a medium containing
urea and phenol red, a dye that turns pink in a pH
of 6.0 or greater. Inexpensive, Only one-half hour
is required for diagnosis of infection, and the test
has shown 98% sensitivity and 100% specificity.
• Invasive technique of choice for diagnosing H.
pylori infection.
34. Noninvasive Techniques:
• Helicobacter pylori Urea Breath Test
Urease activity detected by a breath test.
Urea radioactively labeled with carbon 13
and carbon 14 is ingested. Bacterial urease
splits off labeled carbon dioxide, which can
be detected in the breath. 100% sensitivity
and specificity.
• Detection of IgG
and secretory IgA.
• Enzyme-linked immunosorbent assay (ELISA).
Elevated antibody titer indicates current infection.
Accuracy and low cost makes this test an
attractive choice for detecting H. pylori
35. Treatment of Peptic Ulcer Disease
• Many excellent treatments for peptic
ulcer disease exist.
• In duodenal ulcers and gastric ulcers,
histamine H2-receptors can be blocked
to cause healing in about 90% of cases
within 8 weeks.
• Antibiotics a must.
36. Triple Therapy
• Eradication of Helicobacter pylori is defined as the
absence of the organism four or more weeks after
eradication therapy.
• Eradication rate for single-drug therapy is only 19%
for double-drug therapy is still only 48% . 82%,
achieved by combining
Bismuth + Metronidazole + Tetracycline.
Now when you have to differentiate between bloody diahorreha and and watery diahorrea, PMNs mucosal invasion., PMN`s and blood …. Invasios along with that is accompanying fWatery diahorreea , ETEC, parasite ever , with shigella and Campylobacter campylobacter, and exception to the rule is EHEC.
persistant diahorrea, P parasites, P persistant
Buzz word is seagulls , microaerophilic and grows at 42 o centigrade. ,
42 o c entigrade, u have a patient , isolate every hing is to grow , campylobecter is to grow at 42.
Poultry most common , it can also be feco oral, most likely poultry
To isolate them from stool , most common cause of gastrenteritis in the US no not staph as it is a intoxication .
The good thing is that it is self limiting 3-4 days, about 30 % of GB is attributed to Campmpylobacter , lit bit of cross reactivity and immunological mimimiclry leadind to ascendind paralysis. . U can also have reactive arthiritis. Rehydration however if someone is lingering on
Does not grow at 42 o C , there is only one organism H, Pylori
The most important factor is Urease, ther arent many organism which are urease positive
Cyto toxin s are also virulent factors
Reservoir is humans oral oral feco oral , very easily spreads amongst house holds
H pylori is causing duodenal ulcers.
You will like to know
B cell lymphoma will resolve during treatment About Gastric adeno carcinoma … WHO classified it as type 1 carcinogen , two types of carcinomas
Gold standard is biopsy with culture
Treatment is complex because it is multiple and prolonged, the example I am given you one example , omenaperozol, amoxacillin plus Clathromycin, keeping in mind there are many other combinations. For 2-3 weeks.