Glutamate is the main excitatory neurotransmitter involved in learning and long-term potentiation. It activates NMDA receptors on dendrites which are vital for learning, as shown by experiments where blocking NMDA receptors prevented spatial learning in rats. The hippocampus, amygdala, thalamus, and cerebellum are also involved in learning. The hippocampus is responsible for spatial learning and declarative memory formation. The amygdala is important for emotional learning and fear conditioning. The thalamus initiates and processes fear responses. The cerebellum is involved in motor learning.