The prostate gland is located below the bladder in males and produces fluid for semen. Benign prostatic hyperplasia is a common condition where the prostate enlarges with age, compressing the urethra and impairing urinary flow. Symptoms include frequent urination and weak urine stream. Treatment options include medications to shrink the prostate, heat therapies, and surgeries like transurethral resection of the prostate, which uses an electric knife to remove excess prostate tissue through the urethra.
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. Symptoms may include frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss of bladder control.
Benign prostatic hyperplasia is an enlargement of the prostate gland resulting from an increase in the number of epithelial cells and stromal tissue and developing upward into the bladder and obstructing the outflow of urine.
Gallstones are hardened deposits of bile that can form in your gallbladder. Bile is a digestive fluid produced in your liver and stored in your gallbladder. When you eat, your gallbladder contracts and empties bile into your small intestine (duodenum)
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. Symptoms may include frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss of bladder control.
Benign prostatic hyperplasia is an enlargement of the prostate gland resulting from an increase in the number of epithelial cells and stromal tissue and developing upward into the bladder and obstructing the outflow of urine.
Gallstones are hardened deposits of bile that can form in your gallbladder. Bile is a digestive fluid produced in your liver and stored in your gallbladder. When you eat, your gallbladder contracts and empties bile into your small intestine (duodenum)
Kidney stone disease, also known as urolithiasis, is when a solid piece of material (kidney stone) occurs in the urinary tract. Kidney stones typically form in the kidney and leave the body in the urine stream. A small stone may pass without causing symptoms.
URINARY SYSTEM DISORDERS ARE ONE OF THE MOST PREVALENT GROUP OF DISORDERS THAT NEEDS A THOROUGH UNDERSTANDING. THE MOST BASIC OF THEM ARE URINARY RETENTION AND INCONTINENCE. THIS PRESENTATION DEALS WITH A BRIEF OVERVIEW OF THE DESCRIPTION, CAUSES, DIAGNOSIS AND MANAGEMENT OF THESE DISORDERS IN AN ILLUSTRATED MANNER.
Kidney stone disease, also known as urolithiasis, is when a solid piece of material (kidney stone) occurs in the urinary tract. Kidney stones typically form in the kidney and leave the body in the urine stream. A small stone may pass without causing symptoms.
URINARY SYSTEM DISORDERS ARE ONE OF THE MOST PREVALENT GROUP OF DISORDERS THAT NEEDS A THOROUGH UNDERSTANDING. THE MOST BASIC OF THEM ARE URINARY RETENTION AND INCONTINENCE. THIS PRESENTATION DEALS WITH A BRIEF OVERVIEW OF THE DESCRIPTION, CAUSES, DIAGNOSIS AND MANAGEMENT OF THESE DISORDERS IN AN ILLUSTRATED MANNER.
A benign (not cancer) condition in which an overgrowth of prostate tissue pushes against the urethra and the bladder, blocking the flow of urine. Also called benign prostatic hyperplasia and BPH.
Successful Urology surgery in India by team of expert and international surgeons with advance micro surgical instruments for complex surgery in your budget.
USMLE REPRODUCTIVE 02 The Surgical Anatomy of Prostate .pdfAHMED ASHOUR
The prostate is a walnut-sized gland located below the bladder and in front of the rectum in males. It surrounds the urethra, the tube that carries urine from the bladder out through the penis. The surgical anatomy of the prostate is crucial for procedures such as transurethral resection of the prostate (TURP), prostatectomy, and other interventions related to prostate health.
Understanding the surgical anatomy of the prostate is essential for urologists and surgeons involved in procedures related to prostate health, especially in the context of conditions such as BPH or prostate cancer.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. The Prostate Gland
Clip
Male sex gland
Pear-shape,wt7-
16gm
Size of a walnut
Helps control urine
flow
Produces fluid
component of
semen
Produces Prostate
Specific Antigen
(PSA)
3. Cont….
Benign prostatic hyperplasia (BPH) is the
condition that occurs when
the prostate gland is increasing in size
without there being any malignant cause.
As the prostate enlarges it leads to
compression and then obstruction of
the urethra, which in turn affects urinary
flow.
This condition becomes increasingly
common with age and has an impact on the
quality of life for a considerable number of
men aged over fifty years.
4. Four Areas of the Prostate
Transition Zone
Peripheral Zone
Anterior Zone
Central Zone
5. Definition:
It is an enlargement of portion of
Prostate, enlarges, Extending upward
into the bladder obstructing the
outflow of urine.
6. Causes:
Unknown
Heriditary
Race
Hormonal alteration with endocrine
changes (Testicular Antrogen)
Stimulation of Oestrogen
Aging
Mal function of testis
Diet
Life style issues
Excessive accumulation of dihydro
testosterone.
7. Pathophysiology:
Due to etiological factor
Enlarged nodules tissues of the Prostate
Gland
Compress the urethra
Obstruction of the Urethra
Hypertrophy and bands of the bladder
muscles
8. Cont….
Increased Trabaculation of the bladder wall
Bladder capacity decreases and muscle tone
decreases
Bladder can’t expel the urine on voiding
Urinary Retention
Urine become Alkaline for Bacterial growth
Urinary Obstruction and Irritation
9. Clinical Manifestation:
Fatigue
Anorexia
Nausea & Vomiting
Epigastric Discomfort
Acute urinary retension
Recurrent UTI
Anemia
Prostatism (obstructive and
Irritative
symptoms)
• Hesistancy in starting urination
Haematuria
Hydronephrosis
Pylonephrosis
Renal failure
Azotemianitrogen-
(nitrogen containing compounds in the blood)
Sensation of incomplete
emptying of bladder.
Terminal Dribbling
Nocturia
Abdominal Staining
10. Cont….
Increased frequency of Urination
Dysuria
Urgency
Loss of muscle tone in the bladder
Change in the angle of the bladder
neck.
11. Common symptoms
Decrease in the
urinary stream
Dribbling or leaking
after urination
Intermittency
Hesitancy
Pain or burning
during urination
Feeling that the
bladder never
completely
empties
n
n
n
n
nn
12. Diagnostic Evaluation:
i) History collection
ii) Physical Examination
iii) Rectal Examination (Digital) – It shows the smooth,
firm, symmetric enlargement of the prostate
iv) Urine Analysis
v) Serum creatnine and blood urea nitrogen
vi) Serum prostate and specific Antigen – It is a blood
test to estimate the volume of prostate.
vii) Urodynamic Flow Studies (Cystourethrography)
- Measures peak urine flow rate, voiding time and volume,
status of the bladder’s ability to effectively contract.
13. Cont….
viii) Trans Rectal Ultrasound/catheterization
– It is done to measure of post void residual time.
ix) Cystourethroscopy
- To determine the urethra, bladder and evaluate prostatic
size.
x) Cystoscopy
- It is done to know the size and force of urinary string.
xi) Electro Mylography (EMG)
- It is done to detect any defect in sphincter of muscle
xii) Prostatic Fluid Examination
- The fluid is examinated to determine the infection
xiii) CBC
14. When should BPH be treated?
BPH needs to be treated ONLY IF:
The symptoms are severe enough
to bother patient and affect the
quality of life
Renal insufficiency
Frequent urinary tract infections
n
n
n
16. Medication
First line of defense against bother
some urinary symptoms
Manage the condition - don’t fix it
Two major types:
(Alpha-1-blocker) - relax the
prostate and provide a larger
urethral opening (prazosin, terazosin)
Shrink the prostate gland (5-alpha
reductase inhibitor) (finasteride)
n
n
n
n
n
17. Cont….
Antibiotic Therapy
Alpha-Adrenergic Blockers – To relax
smooth muscle of bladder base and prostate to
facilitate voiding.
Catheterization
Prostatic massage – It is done to reduce the
symptoms and size of prostate.
Phyto therapy – Herbal medicine extracted from
plant.
18. Possible side effects of
Impotence
Dizziness
Headache
Fatigue
Loss of sexual
drive
Medication
n
n
n
n
n
19. Destroy prostate tissue with heat
Tissue is left in the body and is
expelled over time (called sloughing)
Transurethral Microwave Therapy (TUMT)
Transurethral Needle Ablation (TUNA®
)
Interstitial Laser Coagulation (ILC)
Water Induced Thermotherapy (WIT)
Heat therapies
n
n
n
n
n
n
20. Possible side effects of
Urinary Tract Infection
Impotence
Incontinence
heat therapies
n
n
n
22. SURGICAL PROCEDURES
TURP (Trans urethral Prostectomy):
=> It is performed by inserting resectoscope
through the urethra and visualize the inside of the
bladder.
Supra Pubic Prostectomy:
=> It involve a lower abdominal incision
=> Incision is made into the bladder and then
enlarged
tissue is enucleated by blunt dissection.
23. Cont...
.
“Gold Standard” of care for BPH
Uses an electrical “knife” to surgically cut and
remove excess prostate tissue
Effective in relieving symptoms and restoring
urine flow
• Transurethral resection of the prostate:
n
n
n
24. Cont….
Retro-Pubic Prostectomy:
=> It approaches the prostate through a low abdominal
incision without entry into the bladder.
Prostatectomy:
=> To remove hypertrophied portion of the prostate
gland.
Perineal Prostectomy:
=>An incision is made into the perinium between the
anus and the scrotum.
=> Patient must be in the Lithotomy position and
contraindicated for patient with Arthritis and Cardio
pulmonary disease.
25. Cont….
Trans Urethral Incision of the
Prostate(TUIP):
=> It is option for men with a small prostate the is causing
outlet obstruction.
=> Incision are made into the prostatic tissue to enlarge the
lumen of the prostatic urethra.
Trans Urethral Balloon Dilation of the
Prostate:
=> It is done to relax smooth muscle of bladder neck
and
prostate.
=> Small catheter is inserted into the urethra and
balloon is
positioned with in the prostatic urethra and is
26. Cont….
Trans Urethral Ultrasound-Guided
Incision of Prostate:
=>A Laser is used to make the incision into the
prostate
and it usually done in an Ambulatory or Outpatient
setting.
Visual Laser Ablation of the Prostate:
=> Neodynium- Yttrium Aluminum Garnet(YAG) is the
medium that produces to destroy tissue through a
special endoscope.
=> Sloughing of tissue may be delayed and blood loss
is
27. Cont….
Microwave Thermotherapy:
=> It done to relieve necrosis and slough.
Trans Urethral Needle Ablation:
=> It uses Radiofrequency energy to destroy Prostatic
tissue and it is done without anesthesia.
Prostatic Stent:
=> It is done to patient with extremely poor operative
risk
and mesh like tube can be inserted through and
endoscope into the prostatic urethra to open
Mechanically.
29. Nursing Diagnosis:
Impaired urinary elimination r/t obstruction
of urethra.
Pain r/t surgical incision.
Risk for infection r/t Incision, Presence of
catheter.
Risk for fluid volume deficit r/t fluid
replacement needs.
Potential for sexual dysfunction r/t
prostatectomy and UTI.
30. Nursing Mgt.
Pre - operative care:
Inform about the procedure and the expected post
operative care including catheter drainage, Irrigation.
Complication of surgery should be discussed with the
patient.
Prophylactic Antibiotic are ordered.
Bowel preparation is given or the patient is instructed
in home administration and fasting after midnight.
Optimal cardiac, respiratory and circulatory status
should be achieved to decreased risk of complication.
Restoring urine drainage and encouraging high fluid
intake are also helpful in managing the infection.
31. Cont….
Post - operative care:
Maintain patency of catheter system.
Monitor patient for signs of water after TURP.
Instruct patient not to try to void around catheter,
explain feeling of needing to void from pressure of
catheter.
Avoid use of enemas and rectal thermometers.
Give prescribed medication.
Change dressing frequently around suprapubic
wounds.
Give patient opportunities to discuss feelings about
sexuality and possible incontinence.
32. Cont….
Encourage increased fluid and voiding.
Avoid vigorous exercise, heavy lifting and sexual
intercourse at least 3 weeks.
Avoid straining with defecation using stool
softeners or mild laxatives if needed.
Advise to take high diet fiber facilitates the passage
of stool.
Avoid driving for 2 weeks.