Cryptorchidism is the failure of one or both testes to descend into the scrotum. It occurs in approximately 3% of full term and 30% of premature baby boys. There are several types including retractile, palpable, nonpalpable, and ectopic. Risk factors include low birth weight, prematurity, family history, and maternal health conditions. Diagnosis involves physical examination and may include ultrasound, CT scan, or laparoscopy. Treatment is usually hormone therapy or surgery to bring the testes into the scrotum, helping them develop properly and reducing cancer risks.
Hypospadias is a relatively rare congenital condition where the opening of the penis is on the underside of the organ. This condition is more common in infants with a family history of hypospadias.
The penis may curve down in an infant and the baby may spray while urinating.
Hypospadias is a relatively rare congenital condition where the opening of the penis is on the underside of the organ. This condition is more common in infants with a family history of hypospadias.
The penis may curve down in an infant and the baby may spray while urinating.
Bladder exstrophy is a congenital (present at birth) abnormality of the bladder. It happens when the skin over the lower abdominal wall (bottom part of the tummy) does not form properly, so the bladder is open and exposed on the outside of the abdomen. In epispadias, the urethra does not form properly.
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. Symptoms may include frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss of bladder control.
Benign prostatic hyperplasia is an enlargement of the prostate gland resulting from an increase in the number of epithelial cells and stromal tissue and developing upward into the bladder and obstructing the outflow of urine.
Definition
Type of Hernia
risk factor
pathophysiology
diagnostic procedure
physical assessment
management for hernia
Nursing Diagnosis
Health Education
Bladder exstrophy is a congenital (present at birth) abnormality of the bladder. It happens when the skin over the lower abdominal wall (bottom part of the tummy) does not form properly, so the bladder is open and exposed on the outside of the abdomen. In epispadias, the urethra does not form properly.
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. Symptoms may include frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss of bladder control.
Benign prostatic hyperplasia is an enlargement of the prostate gland resulting from an increase in the number of epithelial cells and stromal tissue and developing upward into the bladder and obstructing the outflow of urine.
Definition
Type of Hernia
risk factor
pathophysiology
diagnostic procedure
physical assessment
management for hernia
Nursing Diagnosis
Health Education
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
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the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
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Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...
Cryptorchidism
1. Cryptorchidism
Introduction
Cryptorchidism is derived from the Greek word meaning that-
Crypto – hidden and
orchid - testicle.
It is most common birth defect of the male genitalia.
About 3% of full term and 30% of premature infants boys are born
with at least one undescended testis.
However , about 80% of cryptorchid testes descend by the first year
of life ( the majority within three months ).
2. Definition
Cryptorchidism is the failure of one or both
testes to reach the normal position in the
scrotal sac through the inguinal canal.
Cryptorchidism is the absence of one or both
testes from the scrotum.
3.
4. Types
Retractile or pseudo cryptorchidism:
> A retractile testicle descend into the scrotum but pull back into the
inguinal canal because of a hyperactive cremasteric reflex.
In this type the testicles can be placed in the scrotum manually and stay
there for a short period of time.
Palpable (80%):
>In this type, (also called prepubic or inguinal) the testicle is located
anywhere from just above the scrotum to high in the groin.
5. Cont….
Nonpalpable (15%):
>This means the testicle is in the boy’s abdomen or is absent and not felt
in the scrotum or inguinal canal.
Ectopic (5%):
>In this case, the testicle has taken the wrong path and ended in an
unusual location in the groin area.
6.
7. Etiological factors
The exact cause of an undescended testicle is not known.
A combination of genetics,
Maternal health
Environmental factors might disrupt the hormones,
Physical changes
Nerve activity that influence the development of the
testicles.
8. Cont….
Impairment of the hypothalamic pituitary gonadal axis:
block in the hormonal axis to stimulate the testes to
descend or the testes may fail to respond the stimulus
due to some inherent defects.
Anatomical obstruction: there may be an obstruction in
the pathway of descend or failure of intra abdominal
pressure to rise.
Heredity or chromosomal anomalies: absence of one or
both testes.
Short spermatic cord and artery mechanically prevent
the descend.
Ectopic attachment of the testes.
9. Risk Factors
Factors that might increase the risk of undescended testicle in a newborn
include:
Low birth weight
Premature birth
Family history of undescended testicle or other problems of genital
development
Conditions of the fetus that can restrict growth, such as Down syndrome or an
abdominal wall defect
Alcohol use by the mother during pregnancy.
Cigarette smoking by the mother or exposure to secondhand smoke
Obesity in the mother
Diabetes in the mother — type 1 diabetes, type 2 diabetes or gestational
diabetes
Parents' exposure to some pesticides
10. Pathogenesis
The process of testicular descent is regulated by an interaction
between hormonal and mechanical factors.
The testis develops at 7–8 wk of gestation. At 10–11 wk, the Leyding
cells produce testosterone, which stimulates differentiation of the
wolffian (mesonephric) duct into the epididymis, vas deferens,
seminal vesicle, and ejaculatory duct.
At 32–36 wk, the testis, which is anchored at the internal inguinal
ring by the gubernaculum, begins its process of descent.
The gubernaculum distends the inguinal canal and guides the testis
into the scrotum.
11.
12. Clinical features
A non palpable testis (unable to feel on examination) is the most
common symptom of cryptorchidism.
However, each child may experience symptoms differently.
Symptoms of cryptorchidism may resemble other conditions or
medical problems.
13. Diagnostic measures
Soon after the baby is born or during a routine check-up when they
are six to eight weeks old.
Physical examination
The first stage in diagnosing undescended testicles is to carry out a
physical examination to see whether the testicles can be felt near
the scrotum (palpable) or if they cannot be felt at all (unpalpable).
15. Medical management
In most cases, the testicle will descend without treatment during the
child’s first year. If this does not occur, treatment may include:
Hormone injections (B-HCG or testosterone) to try to bring the
testicle into the scrotum. It also helps in the enlargement of the
testis.
Surgery (orchiopexy) to bring the testicle into the scrotum. This is
the main treatment. If there is an associated hernia, the herniotomy
along with orchidoplexy is indicated.
16. Complications
In order for testicles to develop and function normally, they
need to be slightly cooler than normal body temperature.
The scrotum provides this cooler environment.
Until a boy is 3 or 4 years old, the testicles continue to
undergo changes that affect how well they function later.
17. Complications of a testicle not being located where it is supposed to
be include:
Testicular cancer
Fertility problems
Other complications related to the abnormal location of the
undescended testicle include:
Testicular torsion.
Trauma
Inguinal hernia.
18. Nursing Diagnosis
Fever r/t infection.
Deficient Knowledge related to surgery.
Impaired Urinary Elimination related to the condition and surgical
intervention.
Disturbed Body Image related to appearance of genitalia Risk.
Infection related to surgical incision and drainage tubes.
Risk for Deficient Fluid Volume related to surgical losses.
Acute Pain related to surgical incision and drainage tubes .