The bio-efficacy
of
Andrographis
paniculata
Presented by
Dr. Sudhakar Kokate
Director PPRC, India
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Description
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 Annual plant ht. 1 mtr.
 Family: Acanthaceae
 Geographical distribution: India, South
East Asia, China
 Stem: 3 – 6 mm thick, smooth, dark green
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 Leaves: opposite, decussate, lanceolate in
shape
 Root: woody, simple, fusiform, plant
requires moist habitat
 Herb better in taste and odour is weak
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Chemical constituents
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 diterpene lactones & flavones
 lactones - andrographolide,
8 methylandrograpanin
3 hydrodeoxyandrographolide, etc.
 flavones – wogonin, 7-o-methylwogonin
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 flavones – 7-o-methyldehydrowogonin
5 hydroxy-7,8,2’,5-tetramethylflavone
skullcapflavone-2’-methylether
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Pharmacology
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 possesses anti-inflammatory activity –
neo andrographolide
andrograpanin
 immunomodulatory
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 hepatoprotective
 anti-oxidant
 hypoglycemic activity
 cardiovascular activity
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 anti-tumour
anti-HIV
 anti-fertility
 anti-malarial activity
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Healing power
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 Common cold
 Respiratory
 HIV
 Cough
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Thank you!!

Andrographis paniculata