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Potent Anti-cancer plant
Semecarpus anacardium L.
Presented by
Dr. Sudhakar Kokate
Director PPRC, India
PPRC/INDIA 01
PPRC/INDIA 02
PPRC/INDIA 03
Normal cell Cancer cells
Semecarpus anacardium L.
PPRC/INDIA 05
Description
 Well-known in Ayurveda & Siddha
medicine
 Popularly known as “Marking Nut tree”
 Family: Anacardiaceae
 Medium sized to large tree
 Ht: 15-25 m, grey bark
PPRC/INDIA 08
 Leaves: simple, alternate, obovate
oblong, rounded at the apex
 Flowers: greenish white
 Fruits: ovoid / oblong drupes, 2.5 cm
long
 Nut: 1” x 0.75” x 0.33” Avg. wt: 3.5 gm
PPRC/INDIA 09
Chemicalconstituents
PPRC/INDIA 11
PPRC/INDIA 12
PPRC/INDIA 13
PPRC/INDIA 14
Bio-activity
1. Anti-inflammatory
2. Anti-arthritic
3. Contraceptive agent
4. Hypoglycaemic
5. Lipoxygenase inhibitory
6. Hypo-lipidemic
PPRC/INDIA 16
7. Hypo-cholesterolemic
8. Anti-microbial
9. Anti-stress
10.Spasmogenic effect
11.Immunomodulatory
PPRC/INDIA 17
Anti-tumour-activity
 A variety of “Marking Nut”
preparations used in clinical practice
 Encouraging results reported for
oesophagus, liver, urinary bladder,
cancer and leukaemia
 The flavonoids present in nut have the
ability to prevent various cancers
PPRC/INDIA 19
 It showed differential action in ascites
tumour in the rats
 Extract revealed anti-carcinogenic
activity against AFB1 mediated
hepatocellular carcinoma
 Nut milk extract also showed anti-
tumour activity
PPRC/INDIA 20
 Anti-peroxidative capacity of the nut
extract
 Act as an anti-neoplastic agent
 Regulating the key enzymes
 Significant role in mitochondrial energy
production
PPRC/INDIA 21
Diseasecure
1. Dyspepsia
2. Nervous debility
3. Acute rheumatism
4. Asthma
5. Cough
6. Swelling
PPRC/INDIA 23
7. Piles
8. Helmintic infections
9. Gout
10.Vision improvement
11.Leucoderma
12.Syphilis
PPRC/INDIA 24
13.Gonorrhoea
14.Wound healing
15.Diabetes
16.Urinary diseases
17.Leprosy
PPRC/INDIA 25
Thank you!!

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Semecarpus