This document provides an illustrated guide to proprioceptive neuromuscular facilitation (PNF) in practice. It is the fourth edition of the guide, which has been fully revised with updated content and full-color illustrations. The guide aims to describe the position of PNF within the current holistic treatment spectrum and provide a practical resource for understanding and applying PNF principles and techniques. It covers PNF procedures, techniques, and patterns as well as their application to patient treatment, with a focus on developing readers' understanding and skills. The authors hope this guide will encourage others to continue advancing the PNF approach to physical therapy.