1) King Charles I of Spain (Emperor Charles V) struggled to control his vast empire, which included Spain, the Netherlands, and colonies in the Americas. He faced resistance from Protestant movements and financial problems from constant warfare. 2) During the 1500s, Spain experienced a golden age of art and literature under King Philip II. Notable Spanish artists included El Greco and Velázquez, and writers included Cervantes. 3) Spain declined as a major power under Philip II due to a Dutch revolt, defeat by the English navy against the Spanish Armada, and internal economic problems as the empire spent wealth on warfare.