Radio waves can propagate between two points through four main ways: directly, following the curvature of the Earth, becoming trapped in the atmosphere, or refracting off the ionosphere. Propagation modes include ground-wave, sky-wave, and space-wave propagation. Mobile radio propagation is influenced by factors like reflections, scattering, diffraction, and the electromagnetic properties of materials. Proper propagation modeling is important for wireless system design and performance.