Tooth loss was historically inevitable, but is now preventable. For centuries, dentists extracted teeth due to rampant caries and lack of preventive techniques. After WWII, water fluoridation and dental equipment innovations reduced tooth loss significantly. Studies show caries is the primary cause of tooth loss under age 35, and periodontal disease is primary over age 35. Edentulism remains related to socioeconomic factors and impacts quality of life, demonstrating the need for continued prevention efforts.