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Chapter 1 : 
statistical vs. real models 
Statistical models 
Quantities of interest 
Exponential families
Statistical models 
For most of the course, we assume that the data is a random 
sample x1, . . . , xn and that 
x1, . . . , xn  F(x) 
as i.i.d. variables or as transforms of i.i.d. variables 
Motivation: 
Repetition of observations increases information about F, by virtue 
of probabilistic limit theorems (LLN, CLT)
Statistical models 
For most of the course, we assume that the data is a random 
sample x1, . . . , xn and that 
x1, . . . , xn  F(x) 
as i.i.d. variables or as transforms of i.i.d. variables 
Motivation: 
Repetition of observations increases information about F, by virtue 
of probabilistic limit theorems (LLN, CLT) 
Warning 1: Some aspects of F may ultimately remain unavailable
Statistical models 
For most of the course, we assume that the data is a random 
sample x1, . . . , xn and that 
x1, . . . , xn  F(x) 
as i.i.d. variables or as transforms of i.i.d. variables 
Motivation: 
Repetition of observations increases information about F, by virtue 
of probabilistic limit theorems (LLN, CLT) 
Warning 2: The model is always wrong, even though we behave as 
if...
Limit of averages 
Case of an iid sequence x1, . . . , xn  N(0, 1) 
Evolution of the range of X 
n across 1000 repetitions, along with one random 
sequence and the theoretical 95% range
Limit theorems 
Law of Large Numbers (LLN) 
If X1, . . . ,Xn are i.i.d. random variables, with a well-de
ned 
expectation E[X] 
X1 + . . . + Xn 
n 
prob 
! E[X] 
[proof: see Terry Tao's What's new, 18 June 2008]
Limit theorems 
Law of Large Numbers (LLN) 
If X1, . . . ,Xn are i.i.d. random variables, with a well-de
ned 
expectation E[X] 
X1 + . . . + Xn 
n 
a.s. 
! E[X] 
[proof: see Terry Tao's What's new, 18 June 2008]
Limit theorems 
Law of Large Numbers (LLN) 
If X1, . . . ,Xn are i.i.d. random variables, with a well-de
ned 
expectation E[X] 
X1 + . . . + Xn 
n 
a.s. 
! E[X] 
Central Limit Theorem (CLT) 
If X1, . . . ,Xn are i.i.d. random variables, with a well-de
ned 
expectation E[X] and a
nite variance 2 = var(X), 
p 
n
X1 + . . . + Xn 
n 
- E[X] 

 
dist. 
! N(0, 2) 
[proof: see Terry Tao's What's new, 5 January 2010]
Limit theorems 
Central Limit Theorem (CLT) 
If X1, . . . ,Xn are i.i.d. random variables, with a well-de
ned 
expectation E[X] and a
nite variance 2 = var(X), 
p 
n
X1 + . . . + Xn 
n 
- E[X] 

 
dist. 
! N(0, 2) 
[proof: see Terry Tao's What's new, 5 January 2010] 
Continuity Theorem 
If 
Xn 
dist. 
! a 
and g is continuous at a, then 
g(Xn) 
dist. 
! g(a)
Limit theorems 
Central Limit Theorem (CLT) 
If X1, . . . ,Xn are i.i.d. random variables, with a well-de
ned 
expectation E[X] and a
nite variance 2 = var(X), 
p 
n
X1 + . . . + Xn 
n 
- E[X] 

 
dist. 
! N(0, 2) 
[proof: see Terry Tao's What's new, 5 January 2010] 
Slutsky's Theorem 
If Xn, Yn, Zn converge in distribution to X, a, and b, respectively, 
then 
XnYn + Zn 
dist. 
! aX + b
Limit theorems 
Central Limit Theorem (CLT) 
If X1, . . . ,Xn are i.i.d. random variables, with a well-de
ned 
expectation E[X] and a
nite variance 2 = var(X), 
p 
n
X1 + . . . + Xn 
n 
- E[X] 

 
dist. 
! N(0, 2) 
[proof: see Terry Tao's What's new, 5 January 2010] 
Delta method's Theorem 
If p 
nfXn - g 
dist. 
! Np(0,
) 
and g : Rp ! Rq is a continuously dierentiable function on a 
neighbourhood of  2 Rp, with a non-zero gradient rg(), then 
p 
n fg(Xn) - g()g 
dist. 
! Nq(0,rg()T
rg())
Exemple 1: Binomial sample 
Case # 1: Observation of i.i.d. Bernoulli variables 
xi  B(p) 
with unknown parameter p (e.g., opinion poll) 
Case # 2: Observation of independent Bernoulli variables 
xi  B(pi) 
with unknown and dierent parameters pi (e.g., opinion poll, 
u 
epidemics) 
Transform of i.i.d. u1, . . . , un: 
xi = I(ui 6 pi)
Exemple 1: Binomial sample 
Case # 1: Observation of i.i.d. Bernoulli variables 
xi  B(p) 
with unknown parameter p (e.g., opinion poll) 
Case # 2: Observation of conditionally independent Bernoulli 
variables 
xijzi  B(p(zi)) 
with covariate-driven parameters p(zi) (e.g., opinion poll, 
u 
epidemics) 
Transform of i.i.d. u1, . . . , un: 
xi = I(ui 6 pi)
Parametric versus non-parametric 
Two classes of statistical models: 
Parametric when F varies within a family of distributions 
indexed by a parameter  that belongs to a
nite dimension 
space : 
F 2 fF,  2 g 
and to know F is to know which  it corresponds to 
(identi
ability); 
Non-parametric all other cases, i.e. when F is not constrained 
in a parametric way or when only some aspects of F are of 
interest for inference 
Trivia: Machine-learning does not draw such a strict distinction 
between classes
Parametric versus non-parametric 
Two classes of statistical models: 
Parametric when F varies within a family of distributions 
indexed by a parameter  that belongs to a
nite dimension 
space : 
F 2 fF,  2 g 
and to know F is to know which  it corresponds to 
(identi
ability); 
Non-parametric all other cases, i.e. when F is not constrained 
in a parametric way or when only some aspects of F are of 
interest for inference 
Trivia: Machine-learning does not draw such a strict distinction 
between classes
Non-parametric models 
In non-parametric models, there may still be constraints on the 
range of F`s as for instance 
EF[YjX = x] = 	(
Tx), varF(YjX = x) = 2 
in which case the statistical inference only deals with estimating or 
testing the constrained aspects or providing prediction. 
Note: Estimating a density or a regression function like 	(
Tx) is 
only of interest in a restricted number of cases
Parametric models 
When F = F, inference usually covers the whole of the parameter 
 and provides 
point estimates of , i.e. values substituting for the unknown 
true  
con
dence intervals (or regions) on  as regions likely to 
contain the true  
testing speci
c features of  (true or not?) or of the whole 
family (goodness-of-
t) 
predicting some other variable whose distribution depends on 
 
z1, . . . , zm  G(z) 
Inference: all those procedures depend on the sample (x1, . . . , xn)
Parametric models 
When F = F, inference usually covers the whole of the parameter 
 and provides 
point estimates of , i.e. values substituting for the unknown 
true  
con
dence intervals (or regions) on  as regions likely to 
contain the true  
testing speci
c features of  (true or not?) or of the whole 
family (goodness-of-

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Statistics (1): estimation, Chapter 1: Models

  • 1. Chapter 1 : statistical vs. real models Statistical models Quantities of interest Exponential families
  • 2. Statistical models For most of the course, we assume that the data is a random sample x1, . . . , xn and that x1, . . . , xn F(x) as i.i.d. variables or as transforms of i.i.d. variables Motivation: Repetition of observations increases information about F, by virtue of probabilistic limit theorems (LLN, CLT)
  • 3. Statistical models For most of the course, we assume that the data is a random sample x1, . . . , xn and that x1, . . . , xn F(x) as i.i.d. variables or as transforms of i.i.d. variables Motivation: Repetition of observations increases information about F, by virtue of probabilistic limit theorems (LLN, CLT) Warning 1: Some aspects of F may ultimately remain unavailable
  • 4. Statistical models For most of the course, we assume that the data is a random sample x1, . . . , xn and that x1, . . . , xn F(x) as i.i.d. variables or as transforms of i.i.d. variables Motivation: Repetition of observations increases information about F, by virtue of probabilistic limit theorems (LLN, CLT) Warning 2: The model is always wrong, even though we behave as if...
  • 5. Limit of averages Case of an iid sequence x1, . . . , xn N(0, 1) Evolution of the range of X n across 1000 repetitions, along with one random sequence and the theoretical 95% range
  • 6. Limit theorems Law of Large Numbers (LLN) If X1, . . . ,Xn are i.i.d. random variables, with a well-de
  • 7. ned expectation E[X] X1 + . . . + Xn n prob ! E[X] [proof: see Terry Tao's What's new, 18 June 2008]
  • 8. Limit theorems Law of Large Numbers (LLN) If X1, . . . ,Xn are i.i.d. random variables, with a well-de
  • 9. ned expectation E[X] X1 + . . . + Xn n a.s. ! E[X] [proof: see Terry Tao's What's new, 18 June 2008]
  • 10. Limit theorems Law of Large Numbers (LLN) If X1, . . . ,Xn are i.i.d. random variables, with a well-de
  • 11. ned expectation E[X] X1 + . . . + Xn n a.s. ! E[X] Central Limit Theorem (CLT) If X1, . . . ,Xn are i.i.d. random variables, with a well-de
  • 13. nite variance 2 = var(X), p n
  • 14. X1 + . . . + Xn n - E[X] dist. ! N(0, 2) [proof: see Terry Tao's What's new, 5 January 2010]
  • 15. Limit theorems Central Limit Theorem (CLT) If X1, . . . ,Xn are i.i.d. random variables, with a well-de
  • 17. nite variance 2 = var(X), p n
  • 18. X1 + . . . + Xn n - E[X] dist. ! N(0, 2) [proof: see Terry Tao's What's new, 5 January 2010] Continuity Theorem If Xn dist. ! a and g is continuous at a, then g(Xn) dist. ! g(a)
  • 19. Limit theorems Central Limit Theorem (CLT) If X1, . . . ,Xn are i.i.d. random variables, with a well-de
  • 21. nite variance 2 = var(X), p n
  • 22. X1 + . . . + Xn n - E[X] dist. ! N(0, 2) [proof: see Terry Tao's What's new, 5 January 2010] Slutsky's Theorem If Xn, Yn, Zn converge in distribution to X, a, and b, respectively, then XnYn + Zn dist. ! aX + b
  • 23. Limit theorems Central Limit Theorem (CLT) If X1, . . . ,Xn are i.i.d. random variables, with a well-de
  • 25. nite variance 2 = var(X), p n
  • 26. X1 + . . . + Xn n - E[X] dist. ! N(0, 2) [proof: see Terry Tao's What's new, 5 January 2010] Delta method's Theorem If p nfXn - g dist. ! Np(0, ) and g : Rp ! Rq is a continuously dierentiable function on a neighbourhood of 2 Rp, with a non-zero gradient rg(), then p n fg(Xn) - g()g dist. ! Nq(0,rg()T rg())
  • 27. Exemple 1: Binomial sample Case # 1: Observation of i.i.d. Bernoulli variables xi B(p) with unknown parameter p (e.g., opinion poll) Case # 2: Observation of independent Bernoulli variables xi B(pi) with unknown and dierent parameters pi (e.g., opinion poll, u epidemics) Transform of i.i.d. u1, . . . , un: xi = I(ui 6 pi)
  • 28. Exemple 1: Binomial sample Case # 1: Observation of i.i.d. Bernoulli variables xi B(p) with unknown parameter p (e.g., opinion poll) Case # 2: Observation of conditionally independent Bernoulli variables xijzi B(p(zi)) with covariate-driven parameters p(zi) (e.g., opinion poll, u epidemics) Transform of i.i.d. u1, . . . , un: xi = I(ui 6 pi)
  • 29. Parametric versus non-parametric Two classes of statistical models: Parametric when F varies within a family of distributions indexed by a parameter that belongs to a
  • 30. nite dimension space : F 2 fF, 2 g and to know F is to know which it corresponds to (identi
  • 31. ability); Non-parametric all other cases, i.e. when F is not constrained in a parametric way or when only some aspects of F are of interest for inference Trivia: Machine-learning does not draw such a strict distinction between classes
  • 32. Parametric versus non-parametric Two classes of statistical models: Parametric when F varies within a family of distributions indexed by a parameter that belongs to a
  • 33. nite dimension space : F 2 fF, 2 g and to know F is to know which it corresponds to (identi
  • 34. ability); Non-parametric all other cases, i.e. when F is not constrained in a parametric way or when only some aspects of F are of interest for inference Trivia: Machine-learning does not draw such a strict distinction between classes
  • 35. Non-parametric models In non-parametric models, there may still be constraints on the range of F`s as for instance EF[YjX = x] = (
  • 36. Tx), varF(YjX = x) = 2 in which case the statistical inference only deals with estimating or testing the constrained aspects or providing prediction. Note: Estimating a density or a regression function like (
  • 37. Tx) is only of interest in a restricted number of cases
  • 38. Parametric models When F = F, inference usually covers the whole of the parameter and provides point estimates of , i.e. values substituting for the unknown true con
  • 39. dence intervals (or regions) on as regions likely to contain the true testing speci
  • 40. c features of (true or not?) or of the whole family (goodness-of-
  • 41. t) predicting some other variable whose distribution depends on z1, . . . , zm G(z) Inference: all those procedures depend on the sample (x1, . . . , xn)
  • 42. Parametric models When F = F, inference usually covers the whole of the parameter and provides point estimates of , i.e. values substituting for the unknown true con
  • 43. dence intervals (or regions) on as regions likely to contain the true testing speci
  • 44. c features of (true or not?) or of the whole family (goodness-of-
  • 45. t) predicting some other variable whose distribution depends on z1, . . . , zm G(z) Inference: all those procedures depend on the sample (x1, . . . , xn)
  • 46. Example 1: Binomial experiment again Model: Observation of i.i.d. Bernoulli variables xi B(p) with unknown parameter p (e.g., opinion poll) Questions of interest: 1 likely value of p or range thereof 2 whether or not p exceeds a level p0 3 how many more observations are needed to get an estimation of p precise within two decimals 4 what is the average length of a lucky streak (1's in a row)
  • 47. Exemple 2: Normal sample Model: Observation of i.i.d. Normal variates xi N(, 2) with unknown parameters and 0 (e.g., blood pressure) Questions of interest: 1 likely value of or range thereof 2 whether or not is above the mean of another sample y1, . . . , ym 3 percentage of extreme values in the next batch of m xi's 4 how many more observations to exclude zero from likely values 5 which of the xi's are outliers
  • 48. Quantities of interest Statistical distributions (incompletely) characterised by (1-D) moments: central moments 1 = E[X] = Z xdF(x) k = E h (X - 1)k i k 1 non-central moments k = E Xk k 1 quantile P(X ) = and (2-D) moments cov(Xi, Xj) = Z (xi - E[Xi])(xj - E[Xj])dF(xi, xj) Note: For parametric models, those quantities are transforms of the parameter
  • 49. Example 1: Binomial experiment again Model: Observation of i.i.d. Bernoulli variables Xi B(p) Single parameter p with E[X] = p var(X) = p(1 - p) [somewhat boring...] Median and mode
  • 50. Example 1: Binomial experiment again Model: Observation of i.i.d. Binomial variables Xi B(n, p) P(X = k) = n k pk(1 - p)n-k Single parameter p with E[X] = np var(X) = np(1 - p) [somewhat less boring!] Median and mode
  • 51. Example 2: Normal experiment again Model: Observation of i.i.d. Normal variates xi N(, 2) i = 1, . . . , n , with unknown parameters and 0 (e.g., blood pressure) 1 = E[X] = var(X) = 2 3 = 0 4 = 34 Median and mode equal to
  • 52. Exponential families Class of parametric densities with nice analytic properties Start from the normal density: '(x; ) = 1 p 2 exp x - x2=2 - 2=2 = expf-2=2g p 2 exp fxg exp -x2=2 where and x only interact through single exponential product
  • 53. Exponential families Class of parametric densities with nice analytic properties De
  • 54. nition A parametric family of distributions on X is an exponential family if its density with respect to a measure satis
  • 55. es f(xj) = c()h(x) expfT(x)T()g , 2 , where T() and () are k-dimensional functions and c() and h() are positive unidimensional functions. Function c() is redundant, being de
  • 56. ned by normalising constraint: c()-1 = Z X h(x) expfT(x)T()gd(x) .
  • 57. Exponential families (examples) Example 1: Binomial experiment again Binomial variable X B(n, p) P(X = k) = n k pk(1 - p)n-k can be expressed as P(X = k) = (1 - p)n n k expfk log(p=(1 - p))g hence c(p) = (1 - p)n , h(x) = n x , T(x) = x , (p) = log(p=(1 - p))
  • 58. Exponential families (examples) Example 2: Normal experiment again Normal variate X N(, 2) with parameter = (, 2) and density f(xj) = 1 p 22 expf-(x - )2=22g = 1 p 22 expf-x2=22 + x=2 - 2=22g = expf-2=22g p 22 expf-x2=22 + x=2g hence c() = expf-2=22g p 22 , T(x) = x2 x , () = -1=22 =2
  • 59. natural exponential families reparameterisation induced by the shape of the density: De
  • 60. nition In an exponential family, the natural parameter is () and the natural parameter space is =
  • 61. 2 Rk; Z X h(x) expfT(x)Tgd(x) 1 Example For the B(m, p) distribution, the natural parameter is = logfp=(1 - p)g and the natural parameter space is R
  • 62. natural exponential families reparameterisation induced by the shape of the density: De
  • 63. nition In an exponential family, the natural parameter is () and the natural parameter space is =
  • 64. 2 Rk; Z X h(x) expfT(x)Tgd(x) 1 Example For the B(m, p) distribution, the natural parameter is = logfp=(1 - p)g and the natural parameter space is R
  • 65. regular and minimal exponential families Possible to add/delete useless components of T: De
  • 66. nition A regular exponential family corresponds to the case where is an open set. A minimal exponential family corresponds to the case when the Ti(X)'s are linearly independent, i.e. P(TT(X) = const.) = 0 for 6= 0 Also called non-degenerate exponential family Usual assumption when working with exponential families
  • 67. regular and minimal exponential families Possible to add/delete useless components of T: De
  • 68. nition A regular exponential family corresponds to the case where is an open set. A minimal exponential family corresponds to the case when the Ti(X)'s are linearly independent, i.e. P(TT(X) = const.) = 0 for 6= 0 Also called non-degenerate exponential family Usual assumption when working with exponential families
  • 69. Illustrations For a Normal N(, 2) distribution, f(xj, ) = 1 p 2 1 expf-x2=22 + =2 x - 2=22g means this is a two-dimensional minimal exponential family For a fourth-power distribution f(xj) = C expf-(x - )4gg / e-x4 e43x-62x2+4x3-4 implies this is a three-power distribution [Exercise:
  • 70. nd C]
  • 71. convexity properties Highly regular densities Theorem The natural parameter space of an exponential family is convex and the inverse normalising constant c-1() is a convex function. Example For B(n, p), the natural parameter space is R and the inverse normalising constant (1 + exp())n is convex
  • 72. convexity properties Highly regular densities Theorem The natural parameter space of an exponential family is convex and the inverse normalising constant c-1() is a convex function. Example For B(n, p), the natural parameter space is R and the inverse normalising constant (1 + exp())n is convex
  • 73. analytic properties Lemma If the density of X has the minimal representation f(xj) = c()h(x) expfT(x)Tg then the natural statistic T(X) is also from an exponential family and there exists a measure T such that the density of T(X) against T is c() expftTg
  • 74. analytic properties Theorem If the density of T(X) against T is c() expftTg, if the real value function ' is measurable with Z j'(t)j expftTg dT (t) 1 on the interior of , then f : ! Z '(t) expftTg dT (t) is an analytic function on the interior of and rf() = Z t'(t) expftTg dT (t)
  • 75. analytic properties Theorem If the density of T(X) against T is c() expftTg, if the real value function ' is measurable with Z j'(t)j expftTg dT (t) 1 on the interior of , then f : ! Z '(t) expftTg dT (t) is an analytic function on the interior of and rf() = Z t'(t) expftTg dT (t) Example For B(n, p), the natural parameter space is R and the inverse normalising constant (1 + exp())n is convex
  • 76. moments of exponential families Normalising constant c() inducing all moments Proposition If T(x) 2 Rd and the density of T(X) is expfT(x)T - ()g, then E expfT(x)Tug = expf ( + u) - ()g and () is the cumulant generating function.
  • 77. moments of exponential families Normalising constant c() inducing all moments Proposition If T(x) 2 Rd and the density of T(X) is expfT(x)T - ()g, then E[Ti(x)] = @ () @i i = 1, . . . , d, and E cov(Ti(X), Tj(X)) = @2 () @i@j i, j = 1, . . . , d Sort of integration by part in parameter space: Z
  • 78. Ti() + @ @i c()h(x) expfT(x)Tgd(x) = log c() @ @i 1 = 0
  • 79. further examples of exponential families Example Chi-square 2 k distribution corresponing to distribution of X21 + . . . + X2 k when Xi N(0, 1), with density fk(z) = zk=2-1 expf-z=2g 2k=2 (k=2) z 2 R+
  • 80. further examples of exponential families Counter-Example Non-central chi-square 2 k() distribution corresponing to distribution of X21 + . . . + X2 k when Xi N(, 1), with density fk,(z) = 1=2 (z=)k=4-1=2 expf-(z + )=2gIk=2-1( p z) z 2 R+ where = k2 and I Bessel function of second order
  • 81. further examples of exponential families Counter-Example Fisher Fn,m distribution corresponding to the ratio Z = Yn=n Ym=m n, Ym 2 m , Yn 2 with density fm,n(z) = (n=m)n=2 B(n=2,m=2) zn=2-1 (1 + n=mz)-n+m=2
  • 82. further examples of exponential families Example Ising Be(n=2,m=2) distribution corresponding to the distribution of Z = nY nY +m when Y Fn,m has density fm,n(z) = 1 B(n=2,m=2) zn=2-1 (1 - z)m=2-1 z 2 (0, 1)