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Repairing Coronary Arteries Neal Kleiman Director Cardiac Catheterization Laboratory Methodist DeBakey Heart Center Professor of Medicine Weill Medical College of Cornell University
Courtesy of Dr. Paul Tierstein
Courtesy of Dr. Paul Tierstein
Angioplasty:  The Thirtieth Anniversary Gruntzig Patient
 
Balloon Angioplasty:  The Initial Concept “ Footprints in the snow”
Mechanism of Angioplasty Landau C et al. N Engl J Med 1994;330:981-993
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Angioplasty – The major issue for the last thirty years ,[object Object],[object Object],[object Object]
Chung, I.-M. o et al. J Am Coll Cardiol 2002;40:2072-2081 Restenosis Or “Scar Formation” After Angioplasty – The Role Of Tissue Ingrowth
Why not Scoop out the plaque? DCA picture
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Cumulative Incidence of DES Thrombosis in the Rotterdam-Bern Registry Daemen: Lancet: 2007:369: 667 ,[object Object],[object Object],[object Object],0.6%/year late thrombosis
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New Approaches to Stenting Coronary Arteries ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Evolution of PCI:  The Dominant Coronary Revascularization Therapy  Dr. Don Baim, FDA Panel Meeting December 2006 Progressive improvements in success, safety, and durability, as serial new technologies have been launched.  Innovations over time 0 10 20 30 40 POBA early  POBA late Stent early Stent late DES Event Rate % 1977 1985 1997 1994  2003-present Failure Em CABG Restenosis Stent thrombosis VLST
 

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