One Health – an interdisciplinary approach in combating emerging diseasesILRI
Presentation by Hung Nguyen-Viet, Delia Grace and Jakob Zinsstag at the International Symposium of Health Sciences (iSIHAT 2013), Kuala Lumpur, Malaysia, 20-21 August 2013.
The document discusses the One Health concept and approach. One Health recognizes the interconnectedness of human, animal, and environmental health. It has origins in ancient times but is now defined by the One Health Initiative Task Force as collaborative efforts across disciplines to achieve optimal health for all. A One Health approach is relevant for issues like food safety, zoonotic disease control, and combating antibiotic resistance and requires communication across sectors to better address public health challenges.
Presentation by Delia Grace at the first United Nations Environment Programme (UNEP) Science-Policy Forum ahead of the Second Session of the United Nations Environment Assembly (UNEA-2), Nairobi, Kenya, 20 May 2016.
The One Health approach recognizes that human health, animal health, and environmental health are interconnected. It aims to attain optimal health for people, animals, and the environment through collaboration across multiple disciplines. Key agencies like FAO, OIE, and WHO have developed strategic frameworks to foster cooperation between sectors. Case studies demonstrate how delayed or lack of coordination between human and animal health sectors increased costs and impacted control of diseases like Nipah virus. Antimicrobial resistance is another issue that requires a One Health approach.
The document provides an overview of the One Health approach, which recognizes the interconnectedness of human, animal, and environmental health. It discusses the evolution and key concepts of One Health, including how it addresses important issues like zoonotic diseases, antimicrobial resistance, and food safety in an integrated way. Specific zoonotic diseases that have been targets of the One Health approach in India are also highlighted, such as rabies, henipaviruses, and Japanese encephalitis. The document emphasizes the importance of cross-sectoral collaboration across human, animal, and environmental health to tackle these challenges.
One Health – an interdisciplinary approach in combating emerging diseasesILRI
Presentation by Hung Nguyen-Viet, Delia Grace and Jakob Zinsstag at the International Symposium of Health Sciences (iSIHAT 2013), Kuala Lumpur, Malaysia, 20-21 August 2013.
The document discusses the One Health concept and approach. One Health recognizes the interconnectedness of human, animal, and environmental health. It has origins in ancient times but is now defined by the One Health Initiative Task Force as collaborative efforts across disciplines to achieve optimal health for all. A One Health approach is relevant for issues like food safety, zoonotic disease control, and combating antibiotic resistance and requires communication across sectors to better address public health challenges.
Presentation by Delia Grace at the first United Nations Environment Programme (UNEP) Science-Policy Forum ahead of the Second Session of the United Nations Environment Assembly (UNEA-2), Nairobi, Kenya, 20 May 2016.
The One Health approach recognizes that human health, animal health, and environmental health are interconnected. It aims to attain optimal health for people, animals, and the environment through collaboration across multiple disciplines. Key agencies like FAO, OIE, and WHO have developed strategic frameworks to foster cooperation between sectors. Case studies demonstrate how delayed or lack of coordination between human and animal health sectors increased costs and impacted control of diseases like Nipah virus. Antimicrobial resistance is another issue that requires a One Health approach.
The document provides an overview of the One Health approach, which recognizes the interconnectedness of human, animal, and environmental health. It discusses the evolution and key concepts of One Health, including how it addresses important issues like zoonotic diseases, antimicrobial resistance, and food safety in an integrated way. Specific zoonotic diseases that have been targets of the One Health approach in India are also highlighted, such as rabies, henipaviruses, and Japanese encephalitis. The document emphasizes the importance of cross-sectoral collaboration across human, animal, and environmental health to tackle these challenges.
Tropical diseases are the diseases that are most prevalent in tropical regions of the world. There are around 14 tropical diseases that causes great morbidity but still ranks low in the international health agendas and being "neglected" since it is confined to certain regions and does not spread across the globe. These diseases are eliminated in developed countries but are prevalent in developing countries because of improper sanitation.Here,I hope I have covered almost all the neglected tropical diseases.
emerging and re-emerging vector borne diseasesAnil kumar
this presentation in about emerging and re-emerging vector borne diseases and their spatial spread with reference to time, surveillance, monitoring and management program and other difficulties and suggestions for program
This document discusses emerging and re-emerging infectious diseases. It begins with trends in infectious diseases, then defines emerging and re-emerging diseases. Factors that contribute to emergence include changes in the agent, host, and environment. Examples are provided of diseases that have emerged or re-emerged recently, including SARS, avian influenza, hepatitis C, and antibiotic resistance. The response from public health is also mentioned.
Presented by Hung Nguyen-Viet and Jakob Zinsstag at a technical workshop of the Food and Agriculture Organization of the United Nations (FAO) regional initiative on One Health, Bangkok, Thailand, 11–13 October 2017.
Monkeypox is a zoonotic disease endemic in the Democratic Republic of Congo (DRC) but prevalent also in other countries of Central and Western Africa. The clinical presentation of monkeypox closely resembles the one of smallpox. The mortality rate is officially about 11% however rates as high as 17% have been observed. The disease has been considered rare and not much attention is paid to it. Nonetheless, the incidence of monkeypox increased 20-fold from 1981-1986 to 2005-2007 (two active surveillance programs). More research, surveillance and effective interventions are needed to ensure it would not gain the potential to become the next global pandemic.
This document discusses zoonoses, which are diseases that can be transmitted between animals and humans. It defines zoonoses according to the WHO and notes that over 60% of known human pathogens are zoonotic. The document then provides a brief history of zoonoses and examples throughout time. It also compares the impact of major zoonotic diseases like rabies to other leading causes of death globally. Different classifications of zoonoses are outlined. Factors that can lead to disease emergence are listed, and the roles of wildlife and bush meat in disease transmission are described. Important zoonotic diseases like brucellosis, anthrax, tuberculosis, leptospirosis, and plague are then summarized in terms of
This document discusses several emerging and re-emerging infectious diseases including SARS, MERS, Nipah virus, Chikungunya, West Nile virus, Lyme disease, Kyasanur forest disease. It provides details on the causative agents, modes of transmission, symptoms, treatment and prevention measures for each disease. It also discusses definitions of emerging and re-emerging diseases and factors responsible for their emergence or re-emergence such as rapid population growth, international travel, antibiotic resistance.
Antibiotic resistance is a complex public health issue that requires a One Health approach. The overuse and misuse of antibiotics in human medicine, agriculture, and the environment has contributed to the emergence and spread of antibiotic-resistant bacteria. A holistic, multisectoral response is needed that promotes prudent antibiotic use and prevents infection across human, animal, agricultural, and environmental domains.
1) The document discusses several zoonotic diseases including West Nile virus, rabies, and brucellosis. It describes the pathogens, transmission cycles between animals and humans, clinical manifestations in humans, and national surveillance efforts.
2) For diseases like rabies and brucellosis, the national surveillance involves mandatory reporting of human cases, monitoring of infected animals, and collaboration between human and veterinary agencies.
3) One health approaches discussed include integrating epidemiological data between human and veterinary fields to more rapidly detect and respond to zoonotic outbreaks.
This document provides an overview of emerging and re-emerging infectious diseases. It defines emerging diseases as those whose incidence in humans has increased in recent decades and re-emerging diseases as those that were previously controlled but are increasing again. Factors contributing to disease emergence include evolution of pathogens, changes in human susceptibility and behavior, and environmental changes. The epidemiological triad of host-agent-environment interactions that drive disease transmission is discussed. Several major emerging diseases are outlined such as SARS, Ebola, Nipah virus, and drug-resistant bacteria and their characteristics and origins. Prevention relies on surveillance, research, infrastructure, and public health responses.
One Health approach to address zoonotic and emerging infectious diseases and ...ILRI
Presentation by Hung Nguyen-Viet, Hu Suk Lee, Fred Unger, Arshnee Moodley, Eric Fèvre, Barbara Wieland, Bernard Bett, Michel Dione, Edward Okoth, Johanna Lindahl, Sinh Dang-Xuan and Delia Grace at the virtual 2020 Global ODA Forum for Sustainable Agricultural Development 9–10 November 2020.
One Health is an approach that recognizes the close connections between human, animal, and environmental health. It aims to bring together sectors like human and veterinary medicine to achieve better public health outcomes. The One Health approach is relevant for issues like food safety, controlling zoonotic diseases that can transmit between animals and humans, and combating antibiotic resistance. Zoonotic diseases pose major risks, as over 75% of emerging infectious diseases are zoonotic. The One Health approach requires cross-sectoral collaboration and data sharing to effectively monitor diseases, provide guidance to reduce risks, and prevent pandemics.
The One Health approach aims to achieve optimal health outcomes for people, animals, and the environment through collaboration across multiple disciplines. It recognizes that human, animal, and environmental health are interconnected. The concept originated in the 19th century from physicians who studied links between human and animal diseases. Today, a One Health approach is particularly relevant for issues like food safety, zoonotic disease control, and antibiotic resistance, which require cross-sector solutions. No single group can prevent problems that arise at the human-animal-environment interface. Implementing One Health requires cooperation among professionals in public health, animal health, and related fields across local to global levels.
This document discusses the One Health approach, which recognizes the interconnectedness of human, animal, and environmental health. It notes that zoonotic diseases pose a large disease burden, especially in developing countries, and factors like human encroachment on wildlife habitats, intensive farming, and increased travel and trade have contributed to the emergence and spread of diseases. The One Health approach aims to promote cross-sectoral collaboration between medical, veterinary, and environmental professionals to achieve optimal health outcomes. Key organizations promoting One Health include WHO, FAO, OIE, and CDC. While India has started some One Health initiatives, more coordination is still needed between its medical and veterinary colleges to address zoonotic threats.
This document discusses neglected tropical diseases. It notes that over 1 billion people are affected by one or more neglected tropical diseases, which persist under conditions of poverty. These diseases overlap geographically and individuals are often afflicted by more than one. They remain neglected at the community, national, and international levels. Control efforts have achieved some successes, such as reducing cases of lymphatic filariasis, guinea-worm disease, and trachoma. However, more work is needed to address the impact of these diseases on public health and socioeconomic development.
Just a short update to bring awareness to health care professionals of the monkeypox virus dilemma in 2022,and to inform professionals in Nigeria to be alert as to make diagnosis and inform appropriate authorities. Also, to alert of some of the impediments we face in the undeveloped world in measures against viral infections.
This document discusses viral zoonotic diseases, with a focus on rabies. It defines zoonoses as diseases that can be transmitted between animals and humans. Rabies virus causes progressive infection of the central nervous system. Rabies occurs worldwide except Australia and Antarctica. Transmission is typically through bites from rabid animals, most commonly dogs. Symptoms in humans include pain at the bite site, hydrophobia, and paralysis. Laboratory diagnosis involves detecting the rabies virus or antibodies. Post-exposure prophylaxis includes wound cleansing, rabies immunoglobulin, and rabies vaccines. Prevention relies on surveillance, mass dog vaccination, population control, and public education.
This document discusses disease surveillance and the concept of a public health ecosystem. It describes key aspects of public health including promoting healthy lifestyles, researching disease prevention, and controlling infectious diseases. Disease surveillance is highlighted as a core public health function. An ideal public health information ecosystem is proposed, with different components like surveillance, immunization, and environmental health. The document explores what disease surveillance entails and presents the idea of a disease surveillance ecosystem that brings together different stakeholders like epidemiologists, nurses, and laboratory staff. It addresses current gaps and ways to prioritize and fill them. Finally, it considers exercises around building an ideal disease surveillance team and responding to syndromic surveillance alerts.
The context surrounding the emergence of infectious diseases and the need to ...ILRI
Presentation by Hung Nguyen-Viet at a Preventing Zoonotic Disease Emergence (PREZODE) side event at the Food and Agriculture Organization of the United Nations (FAO) Forum on Science and Innovation, 13 October 2022.
Current research on developing collaborations across sectors for zoonoses pre...ILRI
Presentation by Delia Grace at a national expert consultation on intersectoral coordination for prevention and control of zoonoses in India, New Delhi, India, 27 November 2013.
Tropical diseases are the diseases that are most prevalent in tropical regions of the world. There are around 14 tropical diseases that causes great morbidity but still ranks low in the international health agendas and being "neglected" since it is confined to certain regions and does not spread across the globe. These diseases are eliminated in developed countries but are prevalent in developing countries because of improper sanitation.Here,I hope I have covered almost all the neglected tropical diseases.
emerging and re-emerging vector borne diseasesAnil kumar
this presentation in about emerging and re-emerging vector borne diseases and their spatial spread with reference to time, surveillance, monitoring and management program and other difficulties and suggestions for program
This document discusses emerging and re-emerging infectious diseases. It begins with trends in infectious diseases, then defines emerging and re-emerging diseases. Factors that contribute to emergence include changes in the agent, host, and environment. Examples are provided of diseases that have emerged or re-emerged recently, including SARS, avian influenza, hepatitis C, and antibiotic resistance. The response from public health is also mentioned.
Presented by Hung Nguyen-Viet and Jakob Zinsstag at a technical workshop of the Food and Agriculture Organization of the United Nations (FAO) regional initiative on One Health, Bangkok, Thailand, 11–13 October 2017.
Monkeypox is a zoonotic disease endemic in the Democratic Republic of Congo (DRC) but prevalent also in other countries of Central and Western Africa. The clinical presentation of monkeypox closely resembles the one of smallpox. The mortality rate is officially about 11% however rates as high as 17% have been observed. The disease has been considered rare and not much attention is paid to it. Nonetheless, the incidence of monkeypox increased 20-fold from 1981-1986 to 2005-2007 (two active surveillance programs). More research, surveillance and effective interventions are needed to ensure it would not gain the potential to become the next global pandemic.
This document discusses zoonoses, which are diseases that can be transmitted between animals and humans. It defines zoonoses according to the WHO and notes that over 60% of known human pathogens are zoonotic. The document then provides a brief history of zoonoses and examples throughout time. It also compares the impact of major zoonotic diseases like rabies to other leading causes of death globally. Different classifications of zoonoses are outlined. Factors that can lead to disease emergence are listed, and the roles of wildlife and bush meat in disease transmission are described. Important zoonotic diseases like brucellosis, anthrax, tuberculosis, leptospirosis, and plague are then summarized in terms of
This document discusses several emerging and re-emerging infectious diseases including SARS, MERS, Nipah virus, Chikungunya, West Nile virus, Lyme disease, Kyasanur forest disease. It provides details on the causative agents, modes of transmission, symptoms, treatment and prevention measures for each disease. It also discusses definitions of emerging and re-emerging diseases and factors responsible for their emergence or re-emergence such as rapid population growth, international travel, antibiotic resistance.
Antibiotic resistance is a complex public health issue that requires a One Health approach. The overuse and misuse of antibiotics in human medicine, agriculture, and the environment has contributed to the emergence and spread of antibiotic-resistant bacteria. A holistic, multisectoral response is needed that promotes prudent antibiotic use and prevents infection across human, animal, agricultural, and environmental domains.
1) The document discusses several zoonotic diseases including West Nile virus, rabies, and brucellosis. It describes the pathogens, transmission cycles between animals and humans, clinical manifestations in humans, and national surveillance efforts.
2) For diseases like rabies and brucellosis, the national surveillance involves mandatory reporting of human cases, monitoring of infected animals, and collaboration between human and veterinary agencies.
3) One health approaches discussed include integrating epidemiological data between human and veterinary fields to more rapidly detect and respond to zoonotic outbreaks.
This document provides an overview of emerging and re-emerging infectious diseases. It defines emerging diseases as those whose incidence in humans has increased in recent decades and re-emerging diseases as those that were previously controlled but are increasing again. Factors contributing to disease emergence include evolution of pathogens, changes in human susceptibility and behavior, and environmental changes. The epidemiological triad of host-agent-environment interactions that drive disease transmission is discussed. Several major emerging diseases are outlined such as SARS, Ebola, Nipah virus, and drug-resistant bacteria and their characteristics and origins. Prevention relies on surveillance, research, infrastructure, and public health responses.
One Health approach to address zoonotic and emerging infectious diseases and ...ILRI
Presentation by Hung Nguyen-Viet, Hu Suk Lee, Fred Unger, Arshnee Moodley, Eric Fèvre, Barbara Wieland, Bernard Bett, Michel Dione, Edward Okoth, Johanna Lindahl, Sinh Dang-Xuan and Delia Grace at the virtual 2020 Global ODA Forum for Sustainable Agricultural Development 9–10 November 2020.
One Health is an approach that recognizes the close connections between human, animal, and environmental health. It aims to bring together sectors like human and veterinary medicine to achieve better public health outcomes. The One Health approach is relevant for issues like food safety, controlling zoonotic diseases that can transmit between animals and humans, and combating antibiotic resistance. Zoonotic diseases pose major risks, as over 75% of emerging infectious diseases are zoonotic. The One Health approach requires cross-sectoral collaboration and data sharing to effectively monitor diseases, provide guidance to reduce risks, and prevent pandemics.
The One Health approach aims to achieve optimal health outcomes for people, animals, and the environment through collaboration across multiple disciplines. It recognizes that human, animal, and environmental health are interconnected. The concept originated in the 19th century from physicians who studied links between human and animal diseases. Today, a One Health approach is particularly relevant for issues like food safety, zoonotic disease control, and antibiotic resistance, which require cross-sector solutions. No single group can prevent problems that arise at the human-animal-environment interface. Implementing One Health requires cooperation among professionals in public health, animal health, and related fields across local to global levels.
This document discusses the One Health approach, which recognizes the interconnectedness of human, animal, and environmental health. It notes that zoonotic diseases pose a large disease burden, especially in developing countries, and factors like human encroachment on wildlife habitats, intensive farming, and increased travel and trade have contributed to the emergence and spread of diseases. The One Health approach aims to promote cross-sectoral collaboration between medical, veterinary, and environmental professionals to achieve optimal health outcomes. Key organizations promoting One Health include WHO, FAO, OIE, and CDC. While India has started some One Health initiatives, more coordination is still needed between its medical and veterinary colleges to address zoonotic threats.
This document discusses neglected tropical diseases. It notes that over 1 billion people are affected by one or more neglected tropical diseases, which persist under conditions of poverty. These diseases overlap geographically and individuals are often afflicted by more than one. They remain neglected at the community, national, and international levels. Control efforts have achieved some successes, such as reducing cases of lymphatic filariasis, guinea-worm disease, and trachoma. However, more work is needed to address the impact of these diseases on public health and socioeconomic development.
Just a short update to bring awareness to health care professionals of the monkeypox virus dilemma in 2022,and to inform professionals in Nigeria to be alert as to make diagnosis and inform appropriate authorities. Also, to alert of some of the impediments we face in the undeveloped world in measures against viral infections.
This document discusses viral zoonotic diseases, with a focus on rabies. It defines zoonoses as diseases that can be transmitted between animals and humans. Rabies virus causes progressive infection of the central nervous system. Rabies occurs worldwide except Australia and Antarctica. Transmission is typically through bites from rabid animals, most commonly dogs. Symptoms in humans include pain at the bite site, hydrophobia, and paralysis. Laboratory diagnosis involves detecting the rabies virus or antibodies. Post-exposure prophylaxis includes wound cleansing, rabies immunoglobulin, and rabies vaccines. Prevention relies on surveillance, mass dog vaccination, population control, and public education.
This document discusses disease surveillance and the concept of a public health ecosystem. It describes key aspects of public health including promoting healthy lifestyles, researching disease prevention, and controlling infectious diseases. Disease surveillance is highlighted as a core public health function. An ideal public health information ecosystem is proposed, with different components like surveillance, immunization, and environmental health. The document explores what disease surveillance entails and presents the idea of a disease surveillance ecosystem that brings together different stakeholders like epidemiologists, nurses, and laboratory staff. It addresses current gaps and ways to prioritize and fill them. Finally, it considers exercises around building an ideal disease surveillance team and responding to syndromic surveillance alerts.
The context surrounding the emergence of infectious diseases and the need to ...ILRI
Presentation by Hung Nguyen-Viet at a Preventing Zoonotic Disease Emergence (PREZODE) side event at the Food and Agriculture Organization of the United Nations (FAO) Forum on Science and Innovation, 13 October 2022.
Current research on developing collaborations across sectors for zoonoses pre...ILRI
Presentation by Delia Grace at a national expert consultation on intersectoral coordination for prevention and control of zoonoses in India, New Delhi, India, 27 November 2013.
Dr Paula Fujiwara, Chair of Stop TB Partnership's Global Plan to End TB Task ...CNS www.citizen-news.org
Dr Paula Fujiwara, Chair of Stop TB Partnership's Global Plan to End TB Task Force 2023-2030 presents at AIDS 2022 in a third-party press conference hosted by Asia Pacific Cities Alliance for Health and Development (APCAT) and APCAT Media (Asia Pacific Media Alliance for Health and Development) and CNS.
Thanks
CNS team | www.citizen-news.org
The document discusses the World Society for the Protection of Animals' (WSPA) One Health approach across three areas:
1) Rabies control through mass dog vaccination programs rather than culling, working with governments in countries like Bangladesh and Zanzibar.
2) Disaster preparedness by protecting livestock and integrating animals into response plans, helping communities in India, Haiti, and Kenya become more resilient.
3) Addressing the role of wildlife trade and welfare standards in disease transmission and advocating for more sustainable practices to reduce zoonotic risk.
revised_Rabies report design layout_1-9-15 (high res)Hiral Anil Shah
This document summarizes discussions from a meeting on recent developments in rabies epidemiology and information sources in India. It provides background on rabies as a zoonotic disease in India, noting that India accounts for approximately 20,000 human deaths from rabies annually, or about 50% of the global burden. The meeting brought together experts from human health, veterinary health, wildlife, and other sectors to discuss transmission dynamics of rabies between sectors, management of rabies in India, and costs and benefits of rabies control interventions. Key recommendations included the need for more research on rabies transmission and epidemiology across sectors in India, as well as strengthening inter-sectoral coordination and taking a holistic "one health" approach
Presentation by Professor Robyn Alders, Hub Roadmap Series Lead, at the Special Technical Session on 'Building a resilient biomedical disaster response: learning from the Covid-19 pandemic' organised by The Indian Council of Medical Research (ICMR).
This session was part of the 5th World Congress on Disaster Management (WCDM), which took place in New Delhi, India, in November 2021.
This document summarizes the AIDS epidemic in Eastern and Southern Africa and progress towards meeting international targets on HIV/AIDS. Some key points:
1) There are 34 million people living with HIV globally in 2011, with 1.2 million new infections in Eastern and Southern Africa. Several countries have reduced new infections by over 50% since 2001.
2) Coverage of prevention of mother-to-child transmission services was 72% in 2011 in the region. 5.2 million people were receiving antiretroviral treatment out of 8.1 million estimated to be eligible.
3) Reducing sexual transmission by 50% and reaching 15 million people on HIV treatment by 2015 are among key global targets, but
New faces of tuberculosis: new chellenges requiring new solutionsJean Jacques Bernatas
TB reflects poverty, and while it accompanies Humankind for 70,000 years, this disease presents new faces for which new solutions must be implemented to move towards TB elimination by 2030. Finally a better coordination between all stakeholders is instrumental for winning this fight.
Neglecgted tropical disease: in context to Nepaldipesh125
This document discusses neglected tropical diseases (NTDs) in Nepal. It provides definitions of NTDs from various organizations and lists the common NTD infections. In Nepal, the major NTDs are trachoma, lymphatic filariasis, and soil-transmitted helminthiases. The document outlines national control programs for these diseases and others such as leprosy and dengue. It highlights the high burden of NTDs in Nepal and their impact on vulnerable groups. Integrated control strategies and partnerships are in place to work toward eliminating priority NTDs by targeted years.
Addressing Neglected Parasitic Diseases: Moving towards the development agend...COUNTDOWN on NTDs
This presentation was given by Prof David Molyneux at the British Society of Parasitology Autumn Symposium, held at the Linnean Society in London on 28th September 2017.
http://bsp.uk.net/2016/10/04/bsp-autumn-symposium-2017/
Title - What is going on HIV and AIDS in 2013 and beyond
Presented at the HIV Capacity Summit. view program here - http://www.hivcapacityforum.org/index.php?sid=12
Vaccines and diagnostics—The case for regional One Health centres of excellence ILRI
Vaccines and diagnostics are important tools for One Health approaches to address livestock diseases. Case studies on the East Coast fever vaccine and Newcastle disease vaccine show that while vaccines can be effective, widespread adoption by smallholder farmers faces challenges. Diagnostic tests developed by ILRI for tick-borne diseases have had high impact, though it is difficult to directly attribute impacts. The presentation concludes that while vaccines intuitively could have large scale impacts, enabling adoption among smallholders and pastoralists is difficult, and that disease insights require infrastructure investments for diagnostics.
Presentation given at the launch of COUNTDOWN in CameroonCOUNTDOWN on NTDs
Providing an overview of progress and Neglected Tropical Diseases in Cameroon and highlighting future COUNTDOWN activities, this presentation was given at the launch in Cameroon.
Poster prepared by H. Kiara, Paul Lumu, Harry Oyas, Martin Barasa, Emily Ouma, Karl Rich for the Virtual Annual Planning Meeting ILRI/BMZ Program, Boosting Uganda’s Investment for Livestock Development (BUILD), 10–12 June 2020
One health and its importance; notes - Dr. ROBIN.pptxROBIN VAVACHAN
The document discusses One Health and the interconnectedness of human, animal, and environmental health. It notes that human destruction of biodiversity and disruption of ecosystems can create conditions for diseases like COVID-19 to emerge. When humans disturb natural habitats and kill or cage wild animals, it can release viruses from their natural hosts, with humans becoming the new host. The document advocates for a multisectoral One Health approach involving coordination across human health, animal health, and environmental sectors to address health threats at the human-animal interface.
- TB is the 9th leading cause of death worldwide, with India leading the count of cases and deaths.
- WHO's END TB Strategy and UN SDGs aim to end the global TB epidemic by 2035, reducing incidence by 90% and deaths by 95% from 2015 levels.
- India's NSP 2017-2025, aligned with global strategies, aims to eliminate TB in India by 2025 through a framework with 4 pillars - Detect, Treat, Prevent, Build.
- The strategy calls for multi-sectoral participation from all stakeholders to reach the last person with TB and make India TB-free through improved diagnosis, treatment, social support and an enabling policy environment.
A Review on International Donor Agencies and the Control of Malaria in Nigeri...AJHSSR Journal
The study has examined the role of International Donor Agencies in the control of malaria in
Nigeria. The study becomes necessary because of the increase in cases of malaria and high rate of infant
mortality in the country. The role of donor agencies, national and state ministries of health is very important in
reducing these challenges in Nigeria. The study reviewed available secondary information sources. The study
revealed that the role of International donor agencies includes supporting the State Governments with funds,
provision of free mosquito treated nets, provision of subsidized drugs, provision of vaccines for childhood killer
diseases etc. Some of the challenge affecting donor agencies includes diversion of funds of by relevant bodies
for personal use, lack of political will to implement programme, cultural and religious beliefs about sickness and
illness etc. Based on these, some recommendations were made on the fights against malaria which includes
improved funding by government, zero tolerance to corruption, recruitment of more health personnel,
establishments of more primary health centres especially in the rural areas.
Similar to Rabies the One Health Model - Opportunities and Challenges of a Neglected Tropical Disease (20)
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Disaster risk reduction and nursing - human science research the view of surv...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Global alliance of disaster research institutes (GADRI) discussion session, A...Global Risk Forum GRFDavos
Global Alliance of Disaster Research Institutes (GADRI) aims to reduce disaster risk and increase resilience through interdisciplinary research. GADRI brings together institutions to support research efforts through cooperation instead of competition. It also guides new researchers and maintains institutional memory to build upon past work. Some challenges GADRI may face include coordinating a global alliance. Solutions include facilitating cooperative work between members and guiding the expanding field of disaster reduction research.
Towards a safe, secure and sustainable energy supply the role of resilience i...Global Risk Forum GRFDavos
The document discusses concepts related to ensuring a safe, secure, and sustainable energy supply. It introduces the concepts of risk assessment, resilience management, security of supply, sustainability, and multi-criteria decision analysis. It then presents a case study from the EU SECURE project that used these concepts to evaluate policy scenarios according to various environmental, economic, social, and security indicators. The study found that global climate policy scenarios generally performed best, though they were vulnerable to certain shocks like nuclear accidents or carbon capture failures. Overall policies that reduced fossil fuel use and led to greater diversification of energy sources and imports improved sustainability and security.
Making Hard Choices An Analysis of Settlement Choices and Willingness to Retu...Global Risk Forum GRFDavos
1) The document analyzes data from surveys of Syrian refugees in Turkey to understand their choices regarding returning to Syria, staying in Turkey, or migrating elsewhere.
2) It finds that as the duration of living as a refugee increases, the probability of returning to Syria decreases significantly, while the likelihood of migrating to another country increases.
3) Refugees who experienced greater damage, losses, or deaths due to the war in Syria are less likely to return and more likely to migrate internationally in search of asylum.
The Relocation Challenges in Coastal Urban Centers Options and Limitations, A...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Involving the Mining Sector in Achieving Land Degradation Neutrality, Simone ...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Disaster Risk Reduction and Nursing - Human Science research the view of surv...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Training and awareness raising in Critical Infrastructure Protection & Resili...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
IDRC Davos 2016 - Workshop Awareness Raising, Education and Training - Capaci...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
The document summarizes the Global Alliance of Disaster Research Institutes (GADRI). GADRI is a global network of over 100 disaster research institutes that aims to enhance disaster risk reduction through knowledge sharing. It holds symposia, workshops, and other events on topics like flash floods, earthquakes, and geohazards. Notable upcoming events include the Third Global Summit of Research Institutes for Disaster Risk Reduction in 2017. GADRI's goals are to establish collaborative research initiatives, form international working groups, and disseminate findings to influence disaster policy.
The document discusses capacity development for disaster risk reduction at the national and local levels. It explores strengths and weaknesses of current DRR capacity development efforts, and presents UNITAR's contribution through a new K4Resilience hub initiative. The initiative aims to strengthen DRR capacity development at national and sub-national levels by transferring knowledge and technology, advocating for positive change, achieving economies of scale in training, and facilitating peer-to-peer learning and mainstreaming of knowledge through strategies at the national and sub-national levels.
Dynamic factors influencing the post-disaster resettlement success Lessons fr...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Consequences of the Armed Conflict as a Stressor of Climate Change in Colombi...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Disaster Risk Perception in Cameroon and its Implications for the Rehabilitat...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Systematic Knowledge Sharing of Natural Hazard Damages in Public-private Part...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Exploring the Effectiveness of Humanitarian NGO-Private Sector Collaborations...Global Risk Forum GRFDavos
6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Can UK Water Service Providers Manage Risk and Resilience as Part of a Multi-...Global Risk Forum GRFDavos
The document discusses a study examining how well UK water service providers incorporate risk management and resilience as part of a multi-agency approach. The researchers analyzed 38 Community Risk Registers and found inconsistencies in style, structure, and level of detail when assessing risks like water infrastructure failures or drought. They conclude that improved consistency is needed in how water providers engage in and contribute their risk assessments to the community planning process.
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6th International Disaster and Risk Conference IDRC 2016 Integrative Risk Management - Towards Resilient Cities. 28 August - 01 September 2016 in Davos, Switzerland
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
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Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
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Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Rabies the One Health Model - Opportunities and Challenges of a Neglected Tropical Disease
1. GRF Davos One Health Summit 2013
One Health - One Planet - One Future
Risks and Opportunities
17 - 20 November 2013 in Davos, Switzerland
Rabies the One Health Model Opportunities and Challenges of a NTD
L. Knopf, M.E. Miranda & D.J. Briggs
Global Alliance for Rabies Control (GARC)
2. Rabies: The disease
• Fatal viral disease mainly transmitted through dog bites
- 100% preventable by vaccination
• Every dog bite in canine rabies endemic countries must
be considered a risk of exposure
• 22 million people exposed annually
• Estimated global economic costs $124 billion each year
• Elimination of rabies in dogs would reduce the current
number of human rabies deaths by > 95%
Knobel et al. Bull World Health Organ. 2005;83:360-8.
Hampson et al. OIE Conference on Rabies Control. 2011.
Shwiff et al. Antiviral Research 98(2013)352–356.
2
3. Rabies – a Neglected Tropical Disease
Challenges:
-
Affects marginalized populations
-
Affordability and accessibility of vaccines
-
Responsibilities in cross-sectoral collaboration
-
Animal source (dog), countries‟ other disease
priorities and donors‟ priorities
Opportunities:
-
Model for a „One Health approach‟
-
Vaccine preventable (life saving)
-
Rabies elimination as a global public good
-
Education and community engagement
-
Communication (WRD) and new technologies
4. Some lessons learned
from a GARC perspective
• Rabies prevention is possible
– Essential to support and encourage cross-sector
and cross-community partnerships
– Public/private partnerships are critical – pooling
of resources
• Many tools are already in place
– Vaccines, reduced regimens, dRIT, websites, etc.
– Dog rabies vaccination, en masse
• Communities & governments
– Both are necessary! Build on existing structures
– Education and awareness about rabies are
crucial to communities and sustainability of
programmes.
• Communication networks are powerful
5.
6. Some observations
“Only 0.6% of overseas development
assistance for health is allocated to
NTDs, despite such diseases affecting at
least 1 billion people”
Time frame Nov 2002 – Nov 2012
The Lancet
Malaria
Tuberculosis
HPAI (H5N1)
SARS
Rabies
Leishmaniasis
Leptospirosis
Chagas Disease
7. DALYs Global (in Mio.)
90
80
70
60
50
40
30
20
10
*
0
Malaria
TB
Influenza
Rabies
Leish
Chagas
* Estimates based on 2010 data K.Hampson et al.
8. Partners for Rabies Prevention (PRP)
Informal group of stakeholders – established 2008
• Public and private: Bring time, talent, treasure to table, GARC secretariat
• FAO, OIE, WHO, PAHO, CDC, Animal welfare, Universities, Donors etc.
• Discuss common strategies and synergies
Five pillars: 1. Advocacy; 2. Communications; 3. Research; 4. Capacity building; 5. Pilot projects
Activities:
• Road map for rabies prevention & control: 2008
→ One Health – human and animal rabies prevention
• Blueprint for Canine Rabies Control: 2009–2010
→ First One Health SOP on rabies prevention
• Global health economics group 2011
→ Re-evaluating the global burden of rabies (country basis)
→ Health economic evaluation of on-going rabies prevention projects
• Stepwise Approach to Rabies Elimination for canine rabies endemic countries 2012
→ Develop a stepwise approach to assist countries in rabies control with the ultimate goal of canine
mediated human rabies elimination
• Global rabies policy action group 2013
→ Investigating on models how to translate evidence into policy changes
9. For more information
Global Alliance for Rabies Control
www.rabiesalliance.org
World Rabies Day
http://rabiesalliance.org/world-rabies-day/
Rabies blueprint
www.rabiesblueprint.com
Editor's Notes
Why is that? We know that rabies is a fatal viral disease; that close to 99% of all human deaths are caused by the bite of an infected dog and almost all cases of human rabies occur in Africa and Asia.We also know that rabies is virtually 100% preventable by administering rabies vaccine, even after a person has been bitten by a rabid animal, they can be saved by receiving post-exposure prophylaxis. This is because rabies is a ‘slow’ virus and it takes a while for the virus to travel from the bite wound to the brain and if a person is vaccinated even after exposure to the virus, their own immune system quickly kicks into gear and will provide the necessary antibodies to save them. Comparing the cost of interventions, on average the cost for one person to be vaccinated in Asia and Africa is between 30 to 100 US dollars compared to vaccinating a dog against rabies (and focusing on eliminating rabies at the source of infection) which is about $2 - 5.
This brief presentation has only shown you a small part of what we are doing, but it gives you an idea of the impact that we have had by being able to provide encouragement, tools, education, and some funding to people living in rabies endemic countries that actually want to prevent rabies in their own neighborhoods. It continues to be a remarkably successful story.The lessons we have learned about controlling and preventing rabies are encouraging and yes, we are facing many challenges. For example, we know that:Rabies can be prevented and no one need die of this horrific disease.By working together and pooling our resources, we can have a bigger impact.Communication tools are powerful and by utilizing them, we can save lives and empower communities to improve their own situation.We have many tools in place that can make a difference, including vaccines, reduced cost regimens, new diagnostic tools like the dRIT etc.