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• Perimetry normally tests the light-difference
sensitivity across the visual field.
• This sensitivity reflects the capability of the
eye to perceive a brightness difference
between a test target and its background.
• Light-difference sensitivity depends upon the
tested location on the retina and upon the
parameters of the measurement technique,
such as intensity of background luminance
and target size.
Perimetry
4/14/2020 Ehab Nafie, perimetric printout 2
Octopus Automated
perimetry
Test Pattern
 General/Glaucoma 30° (G1-Program, 32, 30-2, 24-2)
 General/Glaucoma Periphery (G2-Program: 60°; 07-Program: 75°)
 Macula (M-Program (10°/30°); 10-2)
 Screening (ST)
 Driving (Estermann monocular/binocular; FG: German Driving
Licence)
 Disability (BT – Blepharoptosis; BG: German Blindness)
 Other Pathology (N1: Neurological; D1: Diabetes)
 Custom tests.
4/14/2020 Ehab Nafie, perimetric printout 3
4/14/2020 Ehab Nafie, perimetric printout 4
Octopus Automated
perimetry
Octopus Automated
perimetry
Test Methods
• Standard white-on-white perimetry SAP
• Blue/yellow perimetry SWAP
• Flicker perimetry for early diagnosis
• Red/white perimetry (custom tests only)
• Goldmann Kinetic Perimetry
4/14/2020 Ehab Nafie, perimetric printout 5
4/14/2020 Ehab Nafie, perimetric printout 6
Octopus Automated perimetry printout
Humphrey Field Analyzer
4/14/2020 Ehab Nafie, perimetric printout 7
Examination Strategies
 SITA, (Swedish Interactive Threshold
Algorithm) (SITA) Standard and SITA Fast
 Full Threshold
 Fast Pac
Humphrey Field Analyzer
4/14/2020 Ehab Nafie, perimetric printout 8
Perimetry print out
4/14/2020 Ehab Nafie, perimetric printout 9
Reliability
parameters
Gray scale
Pattern
deviation
Global
indices
Probability
symbols
GHT
Patient name
Test
Total deviation
Numeric
sensitivity
4/14/2020 Ehab Nafie, perimetric printout 10
4/14/2020 Ehab Nafie, perimetric printout 11
4/14/2020 Ehab Nafie, perimetric printout 12
An HFA 30-2 dB printout for RT eye
 The tested points
are spaced in an
equidistant grid
pattern, with each
point 6 degrees
apart horizontally
or vertically from
any adjacent
point.
 dB printouts
illustrate the grid
patterns.4/14/2020 Ehab Nafie, perimetric printout 13
30-2 full threshold grid
4/14/2020 Ehab Nafie, perimetric printout 14
Glaucoma hemifield test
 The GHT, devised for the Humphrey Field Analyzer,
compares 24-2 visual fields into 10 regions, with 5
inferior regions representing mirror images of 5
corresponding superior regions.
 Differences between corresponding superior and
inferior zones are compared with the differences
present in the population of normal controls.
4/14/2020 Ehab Nafie, perimetric printout 15
Glaucoma hemifield test
4/14/2020 Ehab Nafie, perimetric printout 16
Glaucoma hemifield test
 Outside normal limits. The GHT is described as
“outside normal limits” when differences between a
matched pair of corresponding zones exceeds the
difference found in 99% of the normal population, or
when both members of a pair of zones are more
abnormal than 99.5% of the individuals with the
normative population.
 Borderline. The GHT is described as borderline when
matched pairs of zones are abnormal at the 97th %
within the normative database,
4/14/2020 Ehab Nafie, perimetric printout 17
Glaucoma hemifield test
General reduction of sensitivity. VFs are described to have
generalized reduction of sensitivity when both conditions for
“outside normal limits” are not met, and the best region of
the VF is depressed to a level at the 99.5th percentile within
individuals of the normative database.
Abnormally high sensitivity. The GHT is described as
having abnormally high sensitivity when the overall
sensitivity in the affected region of the VF is better than
99.5% of individuals within the normative population.
Within normal limits. VFs are described as being within
normal limits when none of the above conditions are met.
4/14/2020 Ehab Nafie, perimetric printout 18
Message
 A GHT message of "outside normal
limits" on two occasions with
corresponding optic nerve or retinal
nerve fiber layer loss is very strong
evidence that glaucomatous visual
field loss is present.
4/14/2020 Ehab Nafie, perimetric printout 19
Patterns of Glaucomatous Visual
Field loss
 Generalized depression
 Paracentral scotoma
 Arcuate or Bjerrum scotoma
 Nasal Step
 Altitudinal Defect
 Temporal Wedge
 Central island
 VF defect must correlate with Optic nerve
damage
4/14/2020 Ehab Nafie, perimetric printout 20
An HFA 24-2 dB printout
RT
LT
4/14/2020 Ehab Nafie, perimetric printout 21
Reliability tests
 Information
about these
factors is at
the top of the
chart.
4/14/2020 Ehab Nafie, perimetric printout 22
Assess reliability
 Diagnostic and management
decisions should not be made on
the basis of unreliable data.
 The three measures of reliability
are
1. fixation losses,
2. false negatives, and
3. false positives.
4/14/2020 Ehab Nafie, perimetric printout 23
Reliability tests
 An examination with a false positive
rate of 15% or higher should be
considered unreliable.
 It is important to recognize that it
may take two or three visual field
examinations for the patient to
produce a reliable and valid visual
field test.
4/14/2020 Ehab Nafie, perimetric printout 24
Reliability tests
 False negatives occur when a
patient does not respond to a
stimulus that should be visible for
that patient.
 Because false negatives increase
with worsening visual field loss, a
high number of false negatives in a
glaucomatous field do not necessarily
represent unreliable data.
4/14/2020 Ehab Nafie, perimetric printout 25
Reliability tests
 False positives, on the other hand, are
always an indicator of an unreliable test.
 They occur when the patient responds when
a response was not expected.
 False positives make the visual field look
better (more sensitive) than it actually is
and may mask shallow depressions.
 Patients with high false positives also may
have a "white" grayscale and/or abnormally
high threshold values, especially in the
peripheral parts of the field.
4/14/2020 Ehab Nafie, perimetric printout 26
Test Duration
 A typical 24-2 threshold test
takes about 7-10 minutes.
 A patient with a very disturbed
field will take longer.
4/14/2020 Ehab Nafie, perimetric printout 27
LT Eye RT Eye
Grey scale
4/14/2020 Ehab Nafie, perimetric printout 28
4/14/2020 Ehab Nafie, perimetric printout 29
Grey scale
4/14/2020 Ehab Nafie, perimetric printout 30
Glaucomatous defects
 Deviation plots and their corresponding
statistical probability plots demand the
most attention.
 These plots identify areas of the field that
are abnormal compared with an age-
matched normal population for each point
tested.
 The information is given both in decibels
and in statistical probability values.
4/14/2020 Ehab Nafie, perimetric printout 31
Glaucomatous defects
 In the probability plots,
increasingly dark squares represent
increasingly significant deviations
from normal.
 The pattern deviation plot gives the
same type of information as the total
deviation plot, after the visual field
has been adjusted for any overall
depression or elevation.
4/14/2020 Ehab Nafie, perimetric printout 32
Pattern deviation plot
 This plot is helpful
in patients who may
have a combined
overall depression
(from media
opacity, for
example) as well as
localized loss from
glaucoma.
4/14/2020 Ehab Nafie, perimetric printout 33
Global indices
 The two global indices used in SITA
testing are mean deviation (MD) and
pattern standard deviation (PSD).
 The MD is a measure of the average
deviation between the patient's
sensitivity and that of age-matched
normal.
4/14/2020 Ehab Nafie, perimetric printout 34
Global indices
 MD is affected by:
 Media opacities,
 Uncorrected refractive error, and
 Small pupils, and it may not reach
statistical significance from a small
or shallow localized glaucomatous
defect.
4/14/2020 Ehab Nafie, perimetric printout 35
Global indices
 PSD is a measure that reflects the shape
or "smoothness" of the hill of vision and is
much more reflective of localized loss,
such as that found in glaucoma.
 It is important to realize, that other
disease processes can cause localized loss
and may result in an elevated pattern
standard deviation.
4/14/2020 Ehab Nafie, perimetric printout 36
Message
 A PSD that reaches the 5% statistical
significance level on multiple
examinations, in the presence of
other suspicious clinical findings, is
very strong evidence that a
glaucomatous visual field defect is
present.
4/14/2020 Ehab Nafie, perimetric printout 37
 When evaluating test reliability, we have
to look at the numbers printed on the
Numeric Results (decibel [dB]) graph.
 A value of 40 dB or higher on this graph
indicates that the patient may be "trigger
happy."
 That is, the patient is anticipating the
presentation of the stimulus and is
responding before the stimulus is seen.
4/14/2020 Ehab Nafie, perimetric printout 38
 Readings of 40 dB or higher indicate
an unreliable field that will need to
be repeated.
 It is best to catch these readings
while the test is in progress and
restart the test.
 A typical "normal" dB reading is
around 30.
4/14/2020 Ehab Nafie, perimetric printout 39
Refraction
 The appropriate refraction
should be listed to allow
proper vision for the
testing distance of the
perimetry bowl.
 Astigmatism more than
1.25 D should be corrected
in addition to the sphere
adjustments.
 Special attention should be
given to aphakic and
pseudophakic patients,
regardless of age, as well
as those who wear contact
lenses.
4/14/2020 Ehab Nafie, perimetric printout 40
Test duration
 A prolonged testing time may
indicate patient fatigue and must be
considered if there is a large
amount of global depression.
 A higher rate of false positives and
negatives may occur at the edges
of scotomas due to glaucoma,
which must be accounted for when
evaluating reliability.
4/14/2020 Ehab Nafie, perimetric printout 41
GHT
within normal limits
MD +2.69 dB
PSD 1.35 dB
4/14/2020 Ehab Nafie, perimetric printout 42
Single Field Analysis – SITA SWAP
4/14/2020 Ehab Nafie, perimetric printout 43
4/14/2020 Ehab Nafie, perimetric printout 44
Visual field interpretation
 Look for signs of unreliable fields: Are there
many false positives (> 15% using SITA), or losses
of fixation (> 33%)?
 Is there a lens rim artifact or uncorrected ptosis?
If the fields appear reliable, continue to step 2.
 Look at the sensitivity map to determine whether
the field is within normal limits.
 If the fields are within normal limits, there is no
further analysis.
 If one or both of the eyes exhibit abnormal fields,
continue to step 3.
4/14/2020 Ehab Nafie, perimetric printout 45
STEP 2: Look for glaucomatous
defects
 Once the field has been deemed
reliable, it should be evaluated for
glaucomatous defects.
 The grayscale should not be used for
decision-making in glaucoma, but it is
helpful to draw attention to areas that
need further evaluation using number
and probability plots.
STEP 3: Look at the GHT and
global indices.
 The GHT is based on the fact that
glaucoma damages the superior and
inferior fields asymmetrically.
 The GHT compares mirror-image
clusters of points in the superior and
inferior fields, and it alerts the clinician
when significant differences are
found between the two hemifields.
Visual field interpretation
 Is the visual field damage present in one or both
eyes?
 If only one eye is affected, the damage is located
in front of the optic chiasm (i.e. the cornea,
vitreous, retina, or optic nerve of only one eye).
 Damage in the visual fields of both eyes could be
due to damage at the level of the optic chiasm
and beyond, or due to separate damage in the
visual pathways of each eye anterior to the
chiasm.
4/14/2020 Ehab Nafie, perimetric printout 48
Visual field interpretation
 Locate the region of the visual field deficit.
 Refer to the patterns of visual field defects chart
to determine the likely region of damage to the
visual pathway.
 Identify the shape of the visual field defect.
 Refer to the chart to determine the likely region
of damage to the visual pathway.
4/14/2020 Ehab Nafie, perimetric printout 49
Visual field interpretation
 Compare these visual fields with each of the
patient's previous visual field tests to identify
progression of visual field loss.
 Do not take a shortcut by comparing these fields
to only the most recent visual field, as this may
be misleading.
 Generally three or more visual field tests are
necessary to evaluate disease progression.
 Consider the findings in the context of the
physical exam findings and the results of other
tests and imaging.
4/14/2020 Ehab Nafie, perimetric printout 50
Not every VF defect is
glaucoma
4/14/2020 Ehab Nafie, perimetric printout 51
4/14/2020 Ehab Nafie, perimetric printout 52

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Prnitout of Humphery field analyezer

  • 1.
  • 2. • Perimetry normally tests the light-difference sensitivity across the visual field. • This sensitivity reflects the capability of the eye to perceive a brightness difference between a test target and its background. • Light-difference sensitivity depends upon the tested location on the retina and upon the parameters of the measurement technique, such as intensity of background luminance and target size. Perimetry 4/14/2020 Ehab Nafie, perimetric printout 2
  • 3. Octopus Automated perimetry Test Pattern  General/Glaucoma 30° (G1-Program, 32, 30-2, 24-2)  General/Glaucoma Periphery (G2-Program: 60°; 07-Program: 75°)  Macula (M-Program (10°/30°); 10-2)  Screening (ST)  Driving (Estermann monocular/binocular; FG: German Driving Licence)  Disability (BT – Blepharoptosis; BG: German Blindness)  Other Pathology (N1: Neurological; D1: Diabetes)  Custom tests. 4/14/2020 Ehab Nafie, perimetric printout 3
  • 4. 4/14/2020 Ehab Nafie, perimetric printout 4 Octopus Automated perimetry
  • 5. Octopus Automated perimetry Test Methods • Standard white-on-white perimetry SAP • Blue/yellow perimetry SWAP • Flicker perimetry for early diagnosis • Red/white perimetry (custom tests only) • Goldmann Kinetic Perimetry 4/14/2020 Ehab Nafie, perimetric printout 5
  • 6. 4/14/2020 Ehab Nafie, perimetric printout 6 Octopus Automated perimetry printout
  • 7. Humphrey Field Analyzer 4/14/2020 Ehab Nafie, perimetric printout 7
  • 8. Examination Strategies  SITA, (Swedish Interactive Threshold Algorithm) (SITA) Standard and SITA Fast  Full Threshold  Fast Pac Humphrey Field Analyzer 4/14/2020 Ehab Nafie, perimetric printout 8
  • 9. Perimetry print out 4/14/2020 Ehab Nafie, perimetric printout 9
  • 10. Reliability parameters Gray scale Pattern deviation Global indices Probability symbols GHT Patient name Test Total deviation Numeric sensitivity 4/14/2020 Ehab Nafie, perimetric printout 10
  • 11. 4/14/2020 Ehab Nafie, perimetric printout 11
  • 12. 4/14/2020 Ehab Nafie, perimetric printout 12
  • 13. An HFA 30-2 dB printout for RT eye  The tested points are spaced in an equidistant grid pattern, with each point 6 degrees apart horizontally or vertically from any adjacent point.  dB printouts illustrate the grid patterns.4/14/2020 Ehab Nafie, perimetric printout 13
  • 14. 30-2 full threshold grid 4/14/2020 Ehab Nafie, perimetric printout 14
  • 15. Glaucoma hemifield test  The GHT, devised for the Humphrey Field Analyzer, compares 24-2 visual fields into 10 regions, with 5 inferior regions representing mirror images of 5 corresponding superior regions.  Differences between corresponding superior and inferior zones are compared with the differences present in the population of normal controls. 4/14/2020 Ehab Nafie, perimetric printout 15
  • 16. Glaucoma hemifield test 4/14/2020 Ehab Nafie, perimetric printout 16
  • 17. Glaucoma hemifield test  Outside normal limits. The GHT is described as “outside normal limits” when differences between a matched pair of corresponding zones exceeds the difference found in 99% of the normal population, or when both members of a pair of zones are more abnormal than 99.5% of the individuals with the normative population.  Borderline. The GHT is described as borderline when matched pairs of zones are abnormal at the 97th % within the normative database, 4/14/2020 Ehab Nafie, perimetric printout 17
  • 18. Glaucoma hemifield test General reduction of sensitivity. VFs are described to have generalized reduction of sensitivity when both conditions for “outside normal limits” are not met, and the best region of the VF is depressed to a level at the 99.5th percentile within individuals of the normative database. Abnormally high sensitivity. The GHT is described as having abnormally high sensitivity when the overall sensitivity in the affected region of the VF is better than 99.5% of individuals within the normative population. Within normal limits. VFs are described as being within normal limits when none of the above conditions are met. 4/14/2020 Ehab Nafie, perimetric printout 18
  • 19. Message  A GHT message of "outside normal limits" on two occasions with corresponding optic nerve or retinal nerve fiber layer loss is very strong evidence that glaucomatous visual field loss is present. 4/14/2020 Ehab Nafie, perimetric printout 19
  • 20. Patterns of Glaucomatous Visual Field loss  Generalized depression  Paracentral scotoma  Arcuate or Bjerrum scotoma  Nasal Step  Altitudinal Defect  Temporal Wedge  Central island  VF defect must correlate with Optic nerve damage 4/14/2020 Ehab Nafie, perimetric printout 20
  • 21. An HFA 24-2 dB printout RT LT 4/14/2020 Ehab Nafie, perimetric printout 21
  • 22. Reliability tests  Information about these factors is at the top of the chart. 4/14/2020 Ehab Nafie, perimetric printout 22
  • 23. Assess reliability  Diagnostic and management decisions should not be made on the basis of unreliable data.  The three measures of reliability are 1. fixation losses, 2. false negatives, and 3. false positives. 4/14/2020 Ehab Nafie, perimetric printout 23
  • 24. Reliability tests  An examination with a false positive rate of 15% or higher should be considered unreliable.  It is important to recognize that it may take two or three visual field examinations for the patient to produce a reliable and valid visual field test. 4/14/2020 Ehab Nafie, perimetric printout 24
  • 25. Reliability tests  False negatives occur when a patient does not respond to a stimulus that should be visible for that patient.  Because false negatives increase with worsening visual field loss, a high number of false negatives in a glaucomatous field do not necessarily represent unreliable data. 4/14/2020 Ehab Nafie, perimetric printout 25
  • 26. Reliability tests  False positives, on the other hand, are always an indicator of an unreliable test.  They occur when the patient responds when a response was not expected.  False positives make the visual field look better (more sensitive) than it actually is and may mask shallow depressions.  Patients with high false positives also may have a "white" grayscale and/or abnormally high threshold values, especially in the peripheral parts of the field. 4/14/2020 Ehab Nafie, perimetric printout 26
  • 27. Test Duration  A typical 24-2 threshold test takes about 7-10 minutes.  A patient with a very disturbed field will take longer. 4/14/2020 Ehab Nafie, perimetric printout 27
  • 28. LT Eye RT Eye Grey scale 4/14/2020 Ehab Nafie, perimetric printout 28
  • 29. 4/14/2020 Ehab Nafie, perimetric printout 29
  • 30. Grey scale 4/14/2020 Ehab Nafie, perimetric printout 30
  • 31. Glaucomatous defects  Deviation plots and their corresponding statistical probability plots demand the most attention.  These plots identify areas of the field that are abnormal compared with an age- matched normal population for each point tested.  The information is given both in decibels and in statistical probability values. 4/14/2020 Ehab Nafie, perimetric printout 31
  • 32. Glaucomatous defects  In the probability plots, increasingly dark squares represent increasingly significant deviations from normal.  The pattern deviation plot gives the same type of information as the total deviation plot, after the visual field has been adjusted for any overall depression or elevation. 4/14/2020 Ehab Nafie, perimetric printout 32
  • 33. Pattern deviation plot  This plot is helpful in patients who may have a combined overall depression (from media opacity, for example) as well as localized loss from glaucoma. 4/14/2020 Ehab Nafie, perimetric printout 33
  • 34. Global indices  The two global indices used in SITA testing are mean deviation (MD) and pattern standard deviation (PSD).  The MD is a measure of the average deviation between the patient's sensitivity and that of age-matched normal. 4/14/2020 Ehab Nafie, perimetric printout 34
  • 35. Global indices  MD is affected by:  Media opacities,  Uncorrected refractive error, and  Small pupils, and it may not reach statistical significance from a small or shallow localized glaucomatous defect. 4/14/2020 Ehab Nafie, perimetric printout 35
  • 36. Global indices  PSD is a measure that reflects the shape or "smoothness" of the hill of vision and is much more reflective of localized loss, such as that found in glaucoma.  It is important to realize, that other disease processes can cause localized loss and may result in an elevated pattern standard deviation. 4/14/2020 Ehab Nafie, perimetric printout 36
  • 37. Message  A PSD that reaches the 5% statistical significance level on multiple examinations, in the presence of other suspicious clinical findings, is very strong evidence that a glaucomatous visual field defect is present. 4/14/2020 Ehab Nafie, perimetric printout 37
  • 38.  When evaluating test reliability, we have to look at the numbers printed on the Numeric Results (decibel [dB]) graph.  A value of 40 dB or higher on this graph indicates that the patient may be "trigger happy."  That is, the patient is anticipating the presentation of the stimulus and is responding before the stimulus is seen. 4/14/2020 Ehab Nafie, perimetric printout 38
  • 39.  Readings of 40 dB or higher indicate an unreliable field that will need to be repeated.  It is best to catch these readings while the test is in progress and restart the test.  A typical "normal" dB reading is around 30. 4/14/2020 Ehab Nafie, perimetric printout 39
  • 40. Refraction  The appropriate refraction should be listed to allow proper vision for the testing distance of the perimetry bowl.  Astigmatism more than 1.25 D should be corrected in addition to the sphere adjustments.  Special attention should be given to aphakic and pseudophakic patients, regardless of age, as well as those who wear contact lenses. 4/14/2020 Ehab Nafie, perimetric printout 40
  • 41. Test duration  A prolonged testing time may indicate patient fatigue and must be considered if there is a large amount of global depression.  A higher rate of false positives and negatives may occur at the edges of scotomas due to glaucoma, which must be accounted for when evaluating reliability. 4/14/2020 Ehab Nafie, perimetric printout 41
  • 42. GHT within normal limits MD +2.69 dB PSD 1.35 dB 4/14/2020 Ehab Nafie, perimetric printout 42
  • 43. Single Field Analysis – SITA SWAP 4/14/2020 Ehab Nafie, perimetric printout 43
  • 44. 4/14/2020 Ehab Nafie, perimetric printout 44
  • 45. Visual field interpretation  Look for signs of unreliable fields: Are there many false positives (> 15% using SITA), or losses of fixation (> 33%)?  Is there a lens rim artifact or uncorrected ptosis? If the fields appear reliable, continue to step 2.  Look at the sensitivity map to determine whether the field is within normal limits.  If the fields are within normal limits, there is no further analysis.  If one or both of the eyes exhibit abnormal fields, continue to step 3. 4/14/2020 Ehab Nafie, perimetric printout 45
  • 46. STEP 2: Look for glaucomatous defects  Once the field has been deemed reliable, it should be evaluated for glaucomatous defects.  The grayscale should not be used for decision-making in glaucoma, but it is helpful to draw attention to areas that need further evaluation using number and probability plots.
  • 47. STEP 3: Look at the GHT and global indices.  The GHT is based on the fact that glaucoma damages the superior and inferior fields asymmetrically.  The GHT compares mirror-image clusters of points in the superior and inferior fields, and it alerts the clinician when significant differences are found between the two hemifields.
  • 48. Visual field interpretation  Is the visual field damage present in one or both eyes?  If only one eye is affected, the damage is located in front of the optic chiasm (i.e. the cornea, vitreous, retina, or optic nerve of only one eye).  Damage in the visual fields of both eyes could be due to damage at the level of the optic chiasm and beyond, or due to separate damage in the visual pathways of each eye anterior to the chiasm. 4/14/2020 Ehab Nafie, perimetric printout 48
  • 49. Visual field interpretation  Locate the region of the visual field deficit.  Refer to the patterns of visual field defects chart to determine the likely region of damage to the visual pathway.  Identify the shape of the visual field defect.  Refer to the chart to determine the likely region of damage to the visual pathway. 4/14/2020 Ehab Nafie, perimetric printout 49
  • 50. Visual field interpretation  Compare these visual fields with each of the patient's previous visual field tests to identify progression of visual field loss.  Do not take a shortcut by comparing these fields to only the most recent visual field, as this may be misleading.  Generally three or more visual field tests are necessary to evaluate disease progression.  Consider the findings in the context of the physical exam findings and the results of other tests and imaging. 4/14/2020 Ehab Nafie, perimetric printout 50
  • 51. Not every VF defect is glaucoma 4/14/2020 Ehab Nafie, perimetric printout 51
  • 52. 4/14/2020 Ehab Nafie, perimetric printout 52