This document discusses pre-anesthetic medication, which refers to drugs administered before general anesthesia to make anesthesia safer. The objectives are sedation to relieve anxiety, pain relief before and after surgery, inhibition of the parasympathetic nervous system to decrease secretions and prevent laryngospasm, acting as an anti-emetic, decreasing gastric acid secretion, and having synergistic effects with general anesthetics. Common pre-anesthetic medications mentioned include benzodiazepines, opioids, anticholinergic drugs, anti-emetics, and drugs to decrease gastric acid production and prevent reflux.

1. Pre-Anaesthetic Medication

2. PRE-ANAESTHETIC MEDICATION
It is the term applied to the
administration of certain drugs prior
to general anaesthetic agent so as to
make anaesthesia safer for the
patient.

3. Objectives of Pre – Anaesthetic Medication
a. Sedation/Relief of anxiety.
b. Relief of Pre-operative& Post-operative pain.
c. Inhibition of Parasympathetic NS:
(1) To decrease salivary & bronchial secretions
(a
and hence prevent reflex laryngospasm.
)
(2) To prevent cardiac arrest due to vagal sti.

4. d. Anti emetic
e. To decrease gastric acid secretion.
f. For Synergic effect with General
Anaesthetics & hence to decrease
their adverse effects .
g) drugs for patients having some
specific illness e.g
pheochromocytoma,
thyrotoxicosis,arrythmias etc

5. SEDATIVES/ANXIOLYTICS
 Benzodiazepine
 diazepam
 lorazepam
 midazolam
 Butyrophenones
 droperidol
 Phenothiazines
 promethazine

6. Barbiturates
OPIOID ANALGESIC
morphine
pethidine
ANTICHOLINERGIC DRUGS
Aropine
hyoscine
glycopyrrolate
ANTIEMETIC
Metoclopramide
promethazine

7. Anticholinergic Drugs
 They decrease secretions of air passages
S0 prevent chocking
Prevent laryngospasm
Prevent cardiac arrest due to excessive
vagal stimu as seen with Halothane
i)Atropine Sulphate
2) Scopolamine (also causes amnesea)
3)Glycopyrrolate(

8. Drugs for prophylaxis of gastric
acid aspiration
 TO DECREASE ACID PRODUCTION
 Antacid.
 H2 Receptor Antagonist: Ranitidine.
 Proton pump inhibitors Omeprazole.
 TO PREVENT REFLUXOF STOMACCONTENS
 Metoclopramide(prokinetic agent).