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Pedigrees lesson
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- 2. Pedigree charts Why dowe use them? Because experimental crosses with humans are not possible. Then what information do we use to determine inheritance of traits? -Medical history -Historical data -Family records
- 3. Pedigree charts Some symbolsto remember: Normal female Female with phenotype of interest Normal male Male with phenotype of interest Normal (sex is unknown) Person with phenotype of interest (unknown sex) Female heterozygous for recessive allele Male heterozygous for recessive allele
- 4. Pedigree charts Some symbolsto remember: Roman numerals I represent generation II First born Last born siblings
- 5. Pedigree charts Some symbolsto remember: I II One-egg Two-egg Monozygotic dizygotic Identical twins fraternal twins
- 6. Pedigree charts How dowe use a pedigree chart? When people have children… Mother’s family Father’s family I II III If this child had a genetic disease, we can trace who it came from by completing the pedigree from family and medical records
- 7. Pedigree charts Hemophilia inthe royal family I II III IV 0
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- 9. Pedigree charts Hemophilia inthe royal family
- 10. Pedigree charts Royal FamilyHistorical Record
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- 12. Pedigree charts Pedigree showingalbinism
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- 14. Pedigree charts Pedigree showingTay Sachs
- 15. Pedigree charts Autosomal recessive: Involves a recessive allele on a non-sex chromosome Autosomal dominant: Involves a dominant allele on a non-sex chromosome X-linked recessive: Involves a recessive allele on the X-chromosome X-linked dominant: Involves a dominant allele on the X-chromosome Y-linked: Involves an allele on the Y-chromosome