Oxygen therapy has been in use for centuries. Oxygen)(O2) is gas used as a drug/medication and a such should be prescribed and administered in the right manner with regards to presenting indications for it's use[1]; which is always in the case of hypoxaemia[2]. It has side effects and specific risks, but, with objective monitoring and administration, it is a potent therapy for the patient with respiratory condition Other indications include: Increased work of breathing Increased myocardial work and/or Myocardial infarction Pulmonary hypertension[5] Pre-oxygenation in induction and difficult intubation. Pre and post suctioning[6] Postoperative oxygenation especially in abdominal and chest surgeries[7] Hyperbaric oxygen therapy indicated in decompression sickness, gas embolism, gas gangrene and carbon monoxide poisoning. Anaemic Hypoxia : it’s benefits is limited due circulatory deficit[8]. In aerosol drug delivery.