Advanced Cardiovascular Life Support (ACLS) is the pre-eminent resuscitation course for the recognition and intervention of cardiopulmonary arrest or other cardiovascular emergencies.
A "bundle" is a
group of evidence-based care components
for a given disease that, when executed together, may result in better outcomes than if implemented individually.
Palliative Care Across the Continuum as presented to the The Palliative Care Summit for PeopleFirst Homecare and Hospice that was held in Snowbird Utah on September 15, 2012, following the Rocky Mountain Geriatric Conference.
The CVP catheter is an important tool used to assess right ventricular function and systemic fluid status. Normal CVP is 2-6 mm Hg. CVP is elevated by : overhydration which increases venous return.
The retarded development of nursing and nursing profession seems to be mainly due to the fact that no serious thought has been given to this discipline.
Dr. Elizabeth Paulk gives an excellent review of palliative care topics including end of life discussions, hospice, pain management, and family counseling.
Advanced Cardiovascular Life Support (ACLS) is the pre-eminent resuscitation course for the recognition and intervention of cardiopulmonary arrest or other cardiovascular emergencies.
A "bundle" is a
group of evidence-based care components
for a given disease that, when executed together, may result in better outcomes than if implemented individually.
Palliative Care Across the Continuum as presented to the The Palliative Care Summit for PeopleFirst Homecare and Hospice that was held in Snowbird Utah on September 15, 2012, following the Rocky Mountain Geriatric Conference.
The CVP catheter is an important tool used to assess right ventricular function and systemic fluid status. Normal CVP is 2-6 mm Hg. CVP is elevated by : overhydration which increases venous return.
The retarded development of nursing and nursing profession seems to be mainly due to the fact that no serious thought has been given to this discipline.
Dr. Elizabeth Paulk gives an excellent review of palliative care topics including end of life discussions, hospice, pain management, and family counseling.
Deciding When Hospice Care is Needed | VITAS HealthcareVITAS Healthcare
The goal of this webinar is to help healthcare professionals address the specific challenges of end-of-life care when determining a terminal prognosis, so they can provide the optimum care for the patient and family during the final stages of life.
Three hour slide deck for basics of palliative care including what is palliative care, symptom management (pain, dyspnea, nausea, constipation), goals-of-care, family meetings, comfort care, and issues around artificial nutrition.
45 minutes of suffering (or Anesthesia Grand Rounds on Palliative Care)Mike Aref
Presentation on what palliative care is, comparison with hospice, primary palliative care screening, goals-of-care, definitions of DNR, basics of acute pain management and WHO analgesic ladder.
Basics of palliative care including symptom management: pain, dyspnea, nausea and constipation; family meetings, goals-of-care, end-of-life care, and artificial nutrition.
The lecture I gave for the Indiana University Health Joint Transplant Education and Research Lecture Series on palliative care. That's right, palliative care in transplant patients NOT at the end-of-life.
Presentation on palliative care given at the Caregiver's Conference for the Cystic Fibrosis Affiliate and Satellite Sites at Riley Children's Hospital.
Oxygen therapy has been in use for centuries. Oxygen)(O2) is gas used as a drug/medication and a such should be prescribed and administered in the right manner with regards to presenting indications for it's use[1]; which is always in the case of hypoxaemia[2]. It has side effects and specific risks, but, with objective monitoring and administration, it is a potent therapy for the patient with respiratory condition
Other indications include:
Increased work of breathing
Increased myocardial work and/or Myocardial infarction
Pulmonary hypertension[5]
Pre-oxygenation in induction and difficult intubation.
Pre and post suctioning[6]
Postoperative oxygenation especially in abdominal and chest surgeries[7]
Hyperbaric oxygen therapy indicated in decompression sickness, gas embolism, gas gangrene and carbon monoxide poisoning.
Anaemic Hypoxia : it’s benefits is limited due circulatory deficit[8].
In aerosol drug delivery.
GENERAL EXAMINATION
CLINICAL SYMPTOMS
On observation kindly check for symptoms like:
1. Decreased level of consciousness: seen in end-stage renal disease (ESRD).
2. Obvious scars: check previous abdominal surgery.
3. Pallor: Suggestive of underlying anaemia (e.g. erythropoietin deficiency).
4. Shortness of breath: may be due to pulmonary oedema secondary to advanced renal disease.
5. Oedema: typically presents as swelling of the limbs (e.g. pedal oedema) and abdomen (i.e. ascites). In the context of a renal system examination, possible causes could include nephrotic syndrome and end-stage renal disease (due to anuria).
6. Cachexia: muscle loss that is not entirely reversed with nutritional supplementation associated with end-stage renal failure due to protein-energy wasting (PEW).
7. Uraemic complexion: a yellow colour of the skin caused by uraemia in advanced chronic kidney disease.
8. Cushingoid appearance: facial puffiness and weight gain may be due to the use of high dose corticosteroids for renal transplant immunosuppression or glomerulonephritis.
he water to be used for the preparation of haemodialysis fluids needs treatment to achieve the appropriate quality. The water treatment is provided by a water pre-treatment system which may include various components such as sediment filters, water softeners, carbon tanks, micro-filters, ultraviolet disinfection units, reverse osmosis units, ultrafilters and storage tanks. The components of the system will be determined by the quality of feed water and the ability of the overall system to produce and maintain appropriate water quality.
ntubation is a process where a healthcare provider inserts a tube through a person's mouth or nose, then down into their trachea (airway/windpipe). The tube keeps the trachea open so that air can get through. The tube can connect to a machine that delivers air or oxygen.
RAPID SEQUENCE INTUBATION:
Rapid sequence induction (RSI) is a set of actions during induction of anaesthesia in unfasted patients or patients at risk of aspiration/regurgitation of gastric contents.
INDUCTIION AGENT:
Induction agents (sedatives) are integral to the performance of rapid sequence intubation (RSI). They provide amnesia, blunt sympathetic responses, and can improve intubating conditions.
CRICHOID PRESSURE:
Cricoid pressure is applied by an assistant using the thumb and second finger; the first finger stabilizes the thumb and finger on the cricoid ring. press directly backwards at a force of 20-30 newtons against the cervical vertebrae.
endotracheal tube selection
Endotracheal tube selection for male is 8.0 and for female is 7.5
Formula for endotracheal tube children in paediatrics is
[(Age/4) + 4] for uncuffed tubes
[(Age/4) +3.5] for cuffed tubes
Immunization is defined as the procedure in which vaccine is injected into body to produce immunity against specifics diseases or it’s a process of protecting person from diseases by vaccination.
• Vaccine term was coined by Louis pasteur.
• Vaccine is a substance that is introduced into the body to prevent the disease produced by certain pathogens.
• Vaccine consists of dead pathogens or live attenuated (artificially weakened) organisms.
• The vaccine induces immunity against the pathogen, either by production of antibodies or by activation of T lymphocytes.
• Edward Jenner produced first live vaccine. He produced the vaccine for smallpox from cowpox virus.
Ventilator associated pneumonia (VAP) was defined as per the Center of Disease Control (CDC) as a pneumonia that occurs in a patient who was intubated and ventilated at the time of or within 48 h before the onset of the event. Pneumonia was identified using a combination of radiological, clinical, and laboratory criteria
Scrub typhus, also known as bush typhus, is a disease caused by a bacteria called ORIENTIA TSUTSUGAMUSHI.
Scrub typhus is spread to people through bites of infected chiggers (larval mites).
Most cases of scrub typhus occur in rural areas of Southeast Asia, Indonesia, China, Japan, India, and northern Australia. Anyone living in or travelling to areas where scrub typhus is found could get infected
Scrub typhus is not transmitted directly from person to person; it is only transmitted by the bites of vectors
Chiggers are abundant in locales with high relative humidity (60%–85%), low temperature (20°C–30°C), low incidence of sunlight, and a dense substrate-vegetative canopy.
Occupational risk is higher in farmers (aged 50–69 years), females.
Deep vein thrombosis (DVT), is the formation of a blood clot in a deep vein, most commonly the legs.[2][a] Symptoms may include pain, swelling, redness, or warmth of the affected area. About half of cases have no symptoms. Complications may include pulmonary embolism, as a result of detachment of a clot which travels to the lungs, and post-thrombotic syndrome.[2][3]
Risk factors include recent surgery, cancer, trauma, lack of movement, obesity, smoking, hormonal birth control, pregnancy and the period following birth, antiphospholipid syndrome, and certain genetic conditions. Genetic factors include deficiencies of antithrombin, protein C, and protein S, and factor V Leiden mutation. The underlying mechanism typically involves some combination of decreased blood flow rate, increased tendency to clot, and injury to the blood vessel wall.
The term inotropic state is most commonly used in reference to various drugs that affect the strength of contraction of heart muscle (myocardial contractility). However, it can also refer to pathological conditions. For example, enlarged heart muscle (ventricular hypertrophy) can increase inotropic state, whereas dead heart muscle (myocardial infarction) can decrease it.
Blood product transfusion and massive transfusionpankaj rana
Blood transfusion
Plastic bag 0.5–0.7 liters containing packed red blood cells in citrate, phosphate, dextrose, and adenine (CPDA) solution
Plastic bag with 0.5–0.7 liters containing packed red blood cells in citrate, phosphate, dextrose, and adenine (CPDA) solution
ICD-9-CM 99.0
MeSH D001803
OPS-301 code 8-80
MedlinePlus 000431
[edit on Wikidata]
Blood transfusion is generally the process of receiving blood or blood products into one's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, white blood cells, plasma, clotting factors, and platelets.
Dengue virus rarely causes death. However, the infection can progress into a more serious condition known as severe dengue or dengue hemorrhagic fever. Symptoms of dengue hemorrhagic fever include: bleeding under the skin. frequent vomiting.
Nosebleeds are very common in young children, affecting most at some time or another. From the outset, it is important to be aware that nosebleeds will often settle down on their own, sometimes requiring medical treatment, but that major underlying causes (blood clotting problems or abnormalities in the nose) are very rare.
Gastrointestinal bleeding (GI bleed), also known as gastrointestinal hemorrhage, is all forms of bleeding in the gastrointestinal tract, from the mouth to the rectum. When there is significant blood loss over a short time, symptoms may include vomiting red blood, vomiting black blood, bloody stool, or black stool.
Malignant hyperthermia (MH) is a disease that causes a fast rise in body temperature and severe muscle contractions when someone with the MH gets general anesthesia. MH is passed down through families. Hyperthermia means high body temperature.
History taking (History of Physical Examination)pankaj rana
A History of Physical Examination Texts and the Conception of Bedside Diagnosis. ... Throughout this paper we construct a difference between a “bedside diagnosis,” made when the physician and patient are in each other's presence, and a “remote diagnosis,” made when the patient and physician are separated.
In hospitals, nursing homes, and other healthcare settings, possible sources of
violence include patients, visitors, intruders, and even coworkers. Examples include
verbal threats or physical attacks by patients, a distraught family member who may
be abusive or even become an active shooter, gang violence in the emergency department,
a domestic dispute that spills over into the workplace, or coworker bullying.
The Glasgow Coma Scale (GCS) is a neurological scale which aims to give a reliable and objective way of recording the conscious state of a person for initial as well as subsequent assessment. A patient is assessed against the criteria of the scale, and the resulting points give a patient score between 3 (indicating deep unconsciousness) and either 14 (original scale) or 15 (more widely used modified or revised scale).
Cardiac tamponade
Synonyms Pericardial tamponade
Hemorragic effusion.jpg
A very large pericardial effusion resulting in tamponade as a result of bleeding from cancer as seen on ultrasound. Closed arrow - the heart; open arrow - the effusion
Specialty Cardiac surgery
Symptoms Shortness of breath, weakness, lightheadedness, cough[1]
Usual onset Rapid or more gradual[2]
Causes Cancer, kidney failure, chest trauma, pericarditis, tuberculosis[2][1]
Diagnostic method Symptoms and ultrasound of the heart[2]
Treatment Drainage (pericardiocentesis, pericardial window, pericardiectomy)[2]
Frequency 2 per 10,000 per year (US)[3]
Cardiac tamponade, also known as pericardial tamponade, is when fluid in the pericardium (the sac around the heart) builds up, resulting in compression of the heart.
Child abuse or child maltreatment is physical, sexual, or psychological maltreatment or neglect of a child or children, especially by a parent or other caregiver. Child abuse may include any act or failure to act by a parent or other caregiver that results in actual or potential harm to a child, and can occur in a child's home, or in the organizations, schools or communities the child interacts with.
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
QA Paediatric dentistry department, Hospital Melaka 2020Azreen Aj
QA study - To improve the 6th monthly recall rate post-comprehensive dental treatment under general anaesthesia in paediatric dentistry department, Hospital Melaka
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
R3 Stem Cells and Kidney Repair: A New Horizon in Nephrology" explores groundbreaking advancements in the use of R3 stem cells for kidney disease treatment. This insightful piece delves into the potential of these cells to regenerate damaged kidney tissue, offering new hope for patients and reshaping the future of nephrology.
How many patients does case series should have In comparison to case reports.pdfpubrica101
Pubrica’s team of researchers and writers create scientific and medical research articles, which may be important resources for authors and practitioners. Pubrica medical writers assist you in creating and revising the introduction by alerting the reader to gaps in the chosen study subject. Our professionals understand the order in which the hypothesis topic is followed by the broad subject, the issue, and the backdrop.
https://pubrica.com/academy/case-study-or-series/how-many-patients-does-case-series-should-have-in-comparison-to-case-reports/
Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
Artificial Intelligence to Optimize Cardiovascular Therapy
End of life care
1. End of life care
Presented by
Pankaj
Nurse Practitioner 2nd
yr
Moderator
Dr. sushant Khanduri
Associate professor
2. END OF LIFE CARE
Palliative Care
Making life as easy as possible for patients
and families living with serious illness
Hospice care
hospice care is given when there is life
expectancy of 6 month or less
3. End of Life in the ICU
10-20% of all ICU patients die
Often illnesses are unanticipated – little
previous discussion of illness with family
Prognostication variable
Culture of aggressive treatment
Patients not generally able to
participate
4. Five Most Common Symptoms
Pain
Nausea/vomiting
Breathlessness
Weight loss
Weakness / fatigue
5. Basics of Pain Management
Use a pain scale
WHO pain ladder
Use standing doses, not PRN
Always have a breakthrough pain plan
10% of daily opioid dose q 1-2 h
Reassess dosage needs daily
6. Assessment of Pain
PQRST
P = Provoking/Palliating factors
Q = Quality in patient’s own words
R = Radiates
S = Severity
T = Time
Recommended instruments:
• McGill Pain Questionnaire (MPQ) and its short form
(SF-MPQ)
9. Neuropathic Pain
Tricyclic Antidepressants (1 in 3 pts
respond)
◦ Desipramine, other TCA’s, venlafaxine
◦ Use limited by CV adverse effects
Gabapentin/Pregabalin (1 in 4 patients
respond)
◦ usual effective dose 900–1800 mg / d; max may be > 3600 mg / d
◦ minimal adverse effects
◦ drowsiness, tolerance develops within days
• Systemic administration of local anesthetics
• Lidocaine or mexiletine effective in 30 RCT’s
• Combination may be the most effective
Brunnhuber, K., Nash, S., Meier, D.E., et al (2008
10. Bone pain
Metastasis to bone
◦ 70% of pt with prostate, breast CA
◦ 30% of pt with thyroid, lung, bladder CA
Multidisciplinary approach, including:
Analgesics: opioids, NSAIDs
Disease modifying therapy (chemotherapy, hormone
therapy)
Corticosteroids
Bisphosphonates
Radiopharmaceuticals (strontium, samarium)
External beam radiation
Orthopedic intervention
External bracing
11. Depression
Loss of social position,
job, prestige, income
Loss of role in family
Insomnia, chronic
fatigue Sense of
helplessness
Disfigurement
Anger
Bureaucratic bungling
Delays in diagnosis
unavailable physicians
uncommunicative
physicians Failure of therapy
Friends who do not visit
Total
Pain
Anxiety
Fear of hospital or nursing home
Fear of pain
Worry about family and
finances Fear of death
Spiritual unrest, uncertainty about future
Physical pain
Other symptoms
Adverse effects of treatment
O'Neill, B., Fallon, M. BMJ 1997, 315p. 801-80
12. Nausea/Vomiting
• Patients with cancer
• 13-17% of terminally ill cancer patients in the last
1-2 weeks of life
• 6-68% of all patients with cancer
Patients with other illnesses:
◦ AIDS: 43% to 49% of patients
◦ Heart disease: 17% to 48% of patients
◦ Renal disease: 30% to 43% of patients
Assessment: simple visual analogue
scales or numerical rating scales
13. Cause Drug Examples
V – Vestibular Cholinergic
Histaminic
Anticholinergic
Antihistaminic
Scopolamine
Promethazine
Diphen-
hydramine
O – Obstructive Cholinergic
Histaminic
5HT3
Drugs stimulating the
myenteric plexus
Senna products
M- Motile
(dysmotility of
upper gut)
Cholinergic
Histaminic
5HT3
Prokinetics
(stimulating 5HT4
receptors)
Prokinetics, metoclo-
pramide
I –
infectious/inflam-
matory
Cholinergic
Histaminic
5HT3
Neurokinin 1
Anticholinergic
Antihistaminic
5HT3 antagonists
Neurokinin 1 ant.
Anti-inflammatory
Scopolamine
Promethazine
Diphenhydramine
Odansetron
Apprepitant
Corticosteroids
Brunnhuber, K., Nash, S., Meier, D.E., et al (2008)See handout for doses, cost
Treat anxiety if present
Management of nausea and vomiting
14. DYSPNEA
Prevalence
◦ 17-30% of patients living with cancer
◦ 90-95% of end-stage COPD patients
◦ 60-88% of end-stage heart disease
patients
Increasingly common as the end of life
approaches
Best assessment is patient report
15. Recent ACP guidelines show evidence
supports treatment with:
◦ Oxygen for hypoxemia
Strong evidence for COPD & exercise
◦ Opioids
Theoretical effect of respiratory
depression not supported by the
literature
◦ Beta-agonists for dyspnea from COPD
Qaseem, A, Snow, V., Shekelle, P, et al. Ann Intern Med.
2008;148:141-146
16. Fatigue
• Approximately 40% of cancer patients
experience fatigue at the time of diagnosis
• Worse during or after chemotherapy
• Higher than 75% in patients with
advanced cancer
• Common with COPD, heart failure
• Multifactorial
• Best evaluated by self-assessment
measures
• No gold standard measurement available
17. Management of Fatigue
Evidence supports use of:
◦ Psychological, psychoeducational interventions
(small)
◦ Methylphenidate – small, significant improvement
• Exercise - small improvement
Energy conservation, activity management -
small but significant effect
No effect: progestational steroids,
paroxetine, or multivitamins.
Insufficient data to recommend any specific
complementary therapies
Brunnhuber, K., Nash, S., Meier,
D.E., et al (2008)
18. Promote energy conservation
Evaluate medications
Optimize fluid, electrolyte intake
Permission to rest
Clarify role of underlying illness
Educate, support patient, family
Include other disciplines
19. Dexamethasone
◦ 4mg PO once daily
◦ feeling of well-being, increased energy
◦ effect may wane after 4-6 weeks
◦ continue until death
Methylphenidate
◦ 5mg PO q 8AM and q noon
◦ May increase up to 20mg daily
Do not give after 2pm to avoid interfering with sleep
20. Anorexia/Cachexia
• Prevalence: 70% of patients with
advanced cancer
• Best assessment is patient report
• Treatments:
• Corticosteroids
• Orally consumed supplements
• Parenteral nutrition
Brunnhuber, K., Nash, S., Meier, D.E., et al (2008)
21. NUTRITION
• High calorie diet
• High protein diet
If patient cannot take orally.
• Try enteral feeding( BEST FEEDING )
• And lastly parenteral nutrition
22. Management
Family education is key
Tailor diet to patient preferences
◦ Fresh fruit
Melon, grapes
◦ Things that are cold and sweet
Ice cream
◦ Lemon drops, zinc lozenges for bad taste in mouth
◦ Most patients do not want dairy, fried foods
Manage grief, disappointment about change in diet
Encourage socializing at meal times even if patient
does not want to eat
23. Depression
Recent ACP Guidelines:
◦ Physicians should screen for and treat
depression in patients facing end-of-life
◦ Evidence supports use of TCA’s and
SSRI’s
◦ Psychosocial interventions also effective
Some providers will use methylphenidate in
patients with very short life expectancy
Qaseem, A, Snow, V., Shekelle, P, et al. AnnIntern Med. 2008;148:141-146
24. Delirium
• Prevalence:
• 20% to 30% of people with cancer, COPD and
end-stage liver disease in SUPPORT
• 26% to 44% in terminal cancer
• 83% in people during their final days.
• Assessment:
• Confusion Assessment Method (CAM)
• Memorial Delirium Assessment Scale
(MDAS)
• Treatment in the terminally ill is difficult
• Prevention is key
25. • Drugs are the most common cause of
delirium
• reduction and possibly withdrawal of
anticholinergic and psychoactive drugs
• opioid dose reduction and/or rotation (usually
at an equi analgesic dose with a reduction of
20% to 30%)
• Newer antipsychotics no better than
haloperidol
26. Pain Ratings For 16 Common Hospital Procedures For 165 Subjects
Urethral catheter
Mechanical restraints
Movement from bed to chair
IM/SC injection
None
IV catheter
Chest x-ray
Vitals signs
Transfer to a procedure
Waiting for a test or procedure
PO medications
severe
Arterial blood gas
Moderate
Central line placement
Nasogastric tube
Peripheral IV insertion
Phlebotomy
Mild
Morrison et al, JPSM 1998
27. EUTHANASIA
• Euthanasia is described as the deliberate and
intentional killing of a person for the benefit
of that person in order to relieve him from
pain and suffering
• The term ‘Euthanasia’ is derived from the
Greek words which literally means “good
death” (Eu=Good; Thanatos=Death).
28. Types
• Euthanasia can be categorized into two types-
active and passive
(a)Active Euthanasia- When a person directly
and deliberately does something which results
in the death of patient.
• It is considered crime in many country and in
India but Netherlands, Belgium, Switzerland is
sanctioned by the passage of “Termination of
Life on Request and Assisted Suicide (Review
Procedures) Act”
29. • Euthanasia can be further classified as
‘voluntary’ where euthanasia is carried out at
the request of the patient and ‘non-voluntary’
where the person is unable to ask for
euthanasia (perhaps because he is
unconscious or otherwise unable to
communicate), or to make a meaningful
choice between living and dying and a
surrogate person takes the decision on his
behalf.
30. Cases
• Now we shall discuss two important
judgments: Airedale case from the House of
Lords, UK and Aruna Shanbaug case from
Supreme Court of India giving us a fair idea
regarding the evolution of the laws pertaining
to Passive Euthanasia in India and the world.
• irreversible coma or Permanent Vegetative
State are indication of ethunasia
33. DNR (Do Not Resuscitate)
DNR (Do Not Resuscitate) is a clear concept in
most developed countries. It involves not
initiating resuscitation in the event of a
cardiac or respiratory arrest.
34. CANDIDATES FOR DNR
• Where life sustaining treatment is likely to be
ineffective or futile.
• -Where patient has prolonged
unconsciousness which is unlikely to recover.
• -Where patient has a terminal condition for
which there is no definitive therapy.
• -Where patient has a chronic debilitating
disorder where burden of resuscitation far
outweighs the benefits.
35. NOT THE CANDIDATES FOR DNR
• Patient is unable to pay for advanced care.
• Where the outcome is doubtful (may or may
not improve situation).
• Where there is conflicting opinion among the
family members.
• Where responsible next of kin is not available
for discussion.
• Where written consent is not available.
36. DNR procedure
• Clear airway
• Inotropic support
• Provide Oxygen
• Position for comfort
• Splint
• Control bleeding
• Provide pain medication
• Provide emotional support
• nutrition
37. Not done in DNR
• Perform chest compressions
• Insert advanced airway
• Administer Cardiac resuscitation drugs
• Provide ventilator assistance including non
invasive ventilation
• Defibrillate
38. CARE OF DEAD BODY
DEAD BODY CARE
After death the body undergoes many physical
changes. So care must be provided as early to
prevent tissue damage /disfigurement of body
parts.
39. Purpose of dead body care
1. To prepare the body for the morgue.
2. To prevent discoloration or deformity of the
body.
3. To protect the body from post mortem
discharge.
40. 1. Check orders for any specimens
2. Ask for special requests to family (eg: shaving , a
special gown , Bible in hand )
3. Remove all equipments , tubes , supplies and
dirty linens.
4. Cleanse the body thoroughly , apply clean
sheets
5. Brush and comb the hairs
6. The eyelids are closed and held in place for a
few seconds , so they remain closed.
7. Dentures should be in the mouth to maintain
facial alignment.
41. 8. Mouth should be closed.
9. Remove all the ornaments.
10. Absorbent pads are placed under the buttocks to take
up any feaces and urine released because of muscle
sphincter relaxation
11. All the orifices should be closed.
12. Cover with a clean sheet up to the chin.
13. Spray a deodorizer to remove unpleasant odor.
14. Apply name tag ( wrist , right big toe)
15. Allow the family members to view the dead body
16. The body is wrapped in a large piece or plastic or
cotton material used to enclose a body after death.
Identification is then applied outside of the wrapper.
42. 17. Hand over all the belongings to the relatives.
18. Do complete documentation in the nursing notes.
Time of death and actions taken to prevent the
death. Who pronounced the death. Any organ
donation Personal articles left on the body Personal
items given to family Time of discharge and
destination of the body Location of name tags on the
body Special request by family
19. Hand over the dead body to the relatives / sent to
the mortuary.