2. Optic atrophy
• Denotes the condition of the optic disc
following degeneration of the optic nerve.
• Classified as;
• Primary optic atrophy
• Secondary optic atrophy
• Conscequtive optic atrophy
• Glaucomatous optic atrophy
3. Primary optic atrophy
• When the atrophy is due to disease proximal to the
disc so there is NO evidence of previous
inflammation.
• CAUSES: Multiple sclerosis
• Space occupying lesions
• Syphilis
4. Clinical features
• Disc is white
• Margins well defined
• Lamina cribrosa seen
• Retina looks normal
• Cupping is shallow
5. Secondary optic atrophy
• Also called post neuritic optic atrophy
• Clinical features:
• Dirty gray colour of the disc
• Margins may be ill defined
• Cup may be obliterated
• Retina may show some evidence of disease
6. Consecutive optic atrophy
• Is a consequence of retinal or choroidal
disease.( Retinitis pigmentosa, Choroidiris,)
• Disc shows a waxy pallor
• Edges are less well defined
• Retinal vessels are contracted
7. Toxic optic Neuropathy
• Is a consequence of Chronic alcohlol
intake,Smoking and with poor nutrition.
• There may be a sudden painless loss of vision
• Usually bilateral
• Disturbed colour perception
• Centro caecal- scotoma
11. Differences
Feature primary secondary conscequtive
colour Chalk white Gray(Dirty) white Waxy pallor
cup shallow Filled up Normal
vessels normal Normal/ attenuated Grossly thinned out
Margins Well defined Blurred Well defined