Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ocular injury ppt Upendra pal optometrist upums saifai etawah
Blunt trauma of the eye
1. Blunt trauma
of the eye
Presented By:
Salwa Ahmed Elkelany
5th year – Ophthalmology department
Faculty of medicine –Suez Canal university
3/27/2017By / Salwa Dohim
2. Types of Ocular injuries :
1. Blunt
2. Perforating
3. Foreign Body
4. Radiation
5. Chemical
6. Thermal
3/27/2017By / Salwa Dohim
4. Injuries occur during blunt
trauma
Coup or direct
Eg: corneal
abrasions
Antero-posterior
compression &
Horizontal
expansion
Eg: rupture globe
Countercoup due to
transmitted pressure
waves to the post.
Pole
Eg : commotio retina
3/27/2017By / Salwa Dohim
5. Modes of injury
- Blunt trauma may occur by :
Direct blow to the eye ball by fist, ball or blunt instruments like sticks, and
big stones.
- Accidental blunt trauma to eye ball
may also occur in accidents, injuries by instruments , fall upon the projecting
blunt objects.
3/27/2017By / Salwa Dohim
8. 1- Closed globe injury
Contusion injuries may vary from a simple corneal abrasion to an extensive
intraocular damage.
CORNEA
o Simple abrasions: Corneal epithelium Damage
(Ulcer)
These are very painful and diagnosed by
fluorescein staining.
These heal within 24hrs with pad and
bandage applied after instilling antibiotic ointment.
3/27/2017By / Salwa Dohim
9. ○ Recurrent corneal erosions
(recurrent keractalgia)
Caused by fingernail trauma. Patient presents with recurrent
attacks of acute pain and lacrimation on opening eye in the
morning and is due to abnormally loose attachment of epithelium
to Bowman’s membrane.
○ Partial corneal tears ( lamellar corneal lacerations )
3/27/2017By / Salwa Dohim
10. BLOOD STAINING OF CORNEA:
hyphaema + Raised IOP
cornea is reddish brown or greenish in color and in later
stages lead to dislocation of lens into anterior chamber.
It clears very slowly from periphery towards the center and
may take up to 2 yrs.
DEEP CORNEAL OPACITY:
* Oedema of corneal stroma
* folds in the Descemet's membrane. 3/27/2017By / Salwa Dohim
11. Sclera
Partial thickness scleral wounds occur alone or
with other lesions of closed globe type.
3/27/2017By / Salwa Dohim
12. Anterior chamber
TRAUMATIC HYPHAEMA or blood in anterior chamber which
occurs due to injury to iris or anterior ciliary vessels.
EXUDATES: these collect here following traumatic uveitis
3/27/2017By / Salwa Dohim
13. Iris , pupil and ciliary body
TRAUMATIC MIOSIS:
occurs initially due to irritation of ciliary nerves or with spasm of
accommodation.
TRAUMATIC MYDRIASIS(iridoplegia):
It is permanent and is associated with traumatic cycloplegia.
RUPTURE OF PUPILARY MARGIN
RADIATING TEARS IN THE IRIS STROMA
IRIDODIALYSIS:
detachment of iris from its root at ciliary body
which results in ‘D’ shaped pupil
* Anti-flexion * Retro-flexion
3/27/2017By / Salwa Dohim
14. TRAUMATIC ANIRIDIA:
the completely torn iris from ciliary body
sinks to the bottom of anterior chamber
in the form of a small ball.
ANGLE RECESSION:
refers to tear between the longitudinal and circular muscle fibres of
ciliary body, characterized by deepening of ant chamber and widening of
ciliary body on gonioscopy and leads to glaucoma.
INFLAMMATORY CHANGES:
these include traumatic iridocyclitis , post traumatic iris atrophy etc.
TTT: consist of atropine , antibiotics and steroids.
3/27/2017By / Salwa Dohim
15. lens
VOSSIUS RING :
It is a circular ring of brown pigment seen on the anterior capsule .
It occurs due to striking of contracted
pupillary margin against the lens.
CONCUSSION CATARACT:
due to imbibition of aqueous and due to direct mechanical effects
of the injury on lens fibers
rosette cataract
3/27/2017By / Salwa Dohim
16. Subluxation of lens : due to partial tear of zonules and there
is displacement of lens but is present in the pupillary area-it
can be lateral or vertical.
Dislocation of lens: when rupture of zonules is complete and
can be intraocular or extraocular.
INTRAOCULAR into anterior chamber or posterior vitreous
EXTRAOCULAR subconjunctival space or may fall outside the eye
3/27/2017By / Salwa Dohim
18. VITREOUS
Liquefaction and appearance of clouds of fine
pigmentary opacities.
Detachment of the vitreous either anterior or
posterior.
Vitreous hemorrhage .
Vitreous herniation in anterior chamber may occur
with subluxation or dislocation of lens.
3/27/2017By / Salwa Dohim
19. Choroid
Rupture of choroid: is concentric to optic disc and situated
temporal to it and can be single or multiple.
On fundus examination :
whitish crescent with fine
pigmentation at its margins .
Retinal vessels pass over it.
3/27/2017By / Salwa Dohim
20. - Choroidal hemorrhage may occur under retina
or may even enter the vitreous if retina is torn.
- Choroidal detachment
- Traumatic choroiditis :
seen on fundus examination as patches
of pigmentation and discoloration after eye becomes silent.
3/27/2017By / Salwa Dohim
21. Retina
COMMOTIO RETINAE(Berlin’s oedema):
It manifests as milky white cloudiness involving of posterior pole
with a cherry- red spot in the foveal region .
disappear after some days pigmentary changes.
RETINAL HAEMORRHAGES:
eg: flame shaped and preretinal D shaped haemorrhage may be
associated with traumatic retinopathy.
RETINAL TEARS:
these follow a contusion in eyes suffering from myopia or senile
degenerations.
3/27/2017By / Salwa Dohim
22. TRAUMATIC PROLIFERATIVE RETINOPATHY :
occur secondary to vitreous haemorrhage.
RETINAL DETACHMENT:
follows retinal tears or vitreo-retinal tractional bands.
CONCUSSION CHANGES AT MACULA: traumatic macular oedema
followed by pigmentary degeneration.
Sometimes, a macular cyst is formed , which on rupture is
converted to a lamellar or full thickness macular hole.
3/27/2017By / Salwa Dohim
23. IOP changes in closed globe injury
TRAUMATIC GLAUCOMA
TRAUMATIC HYPOTONY
it may follow damage to the ciliary body.
3/27/2017By / Salwa Dohim
24. Traumatic changes in refraction
Myopia may follow ciliary spasm or rupture of zonules or
anterior shift of lens
Hypermetropia and loss of accommodation may result
from damage to the ciliary body(cycloplegia).
3/27/2017By / Salwa Dohim
25. 2- GLOBE RUPTURE
It is a full-thickness wound of eye-wall caused by blunt object and
can occur in 2 ways:
DIRECT RUPTURE: at the site of injury.
INDIRECT RUPTURE : occurs because of compression force .The
impact results in momentary increase in IOP and inside out injury at the
weakest part of the eye wall
TREATMENT:
A badly damaged globe should be enucleated .
In less severe cases it can be repaired under general anesthesia.
3/27/2017By / Salwa Dohim
26. Eye lids lesion Conjunctival Injury Orbital injury Optic n. Injury
- Laceration and avulsion of
lids may occur .
subconjunctival
hemorrhage
-fracture of orbital walls.
-Orbital hemorrhage
sudden proptosis
-Orbital emphysema may
occur following ethmoidal
sinus rupture
associated with
fracture of base
of skull
3- Extraocular lesions
3/27/2017By / Salwa Dohim
30. You can refer to :
http://eyewiki.aao.org/Ocular_Trauma%3A_Acute_Evaluation,_Cataract,_G
laucoma
http://www.medscape.com/viewarticle/813605
3/27/2017By / Salwa Dohim