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 Define common urological emergencies
that may face non urologists.
 How to diagnose these emergencies
 Initial management of these problems
for non urologists
1 Loin pain
2 Retention of urine
3 Testicular pain
4 Hematuria
5 Problems with the penis
6 Problems with catheters
 Acute renal colic is the most
excruciatingly painful event a person can
endure .
Non traumatic
emergency
 Does not always present with classic history
 Classically presents with loin pain radiating
around abdomen, as stone moves down
ureter
 May get testicular/labial pain +/- strangury if
stone impacts at VUJ
- Reflects the somatic
sensory distribution
of the spinal level of
renal innervations
- (T1o-T12).
- Most probable
hypothesis:
Afferents from the
skin & viscera
converge on the
same neuron in the
spinal cord and
share the same
ascending neuron .
 Urinalysis
 CBC
 BUN & s. Creatinine
 KUB
 KUB
 Limitations
 Significant
obstruction may be
associated with little
dilatation of
collecting system.
 Relatively poor in
visualizing the ureter.
 Difficult to detect
stones < 5mm in size
 Operator and
equipment
dependent
 95% sensitivity
 98% specificity
 Performed in 5 min.
 Identifies radiolucent
stones .
 Identifies other causes
of flank pain.
stone
 Treat the symptoms –analgesia
 Blood cultures if pyrexial
Consider antibiotics
quinolone if not vomiting
gentamicin if vomiting
 Persistent pain .
 Ureteral obstruction from a stone in a
solitary or transplanted kidney .
 Ureteral obstruction from a stone in
presence of UTI, fever, sepsis or
pyonephrosis.
 Relative indication:
Co morbid conditions (e.g. diabetes ,
dehydration, renal failure, or any immuno
compromised state)
Size of Stone
< 4mm
4-6 mm
> 6mm
Management
Conservative: 90% pass
spontaneously
50% pass
spontaneously – trial
of passage
Intervention likely, only
10% pass
spontaneously
 Stone on KUB - No stone on KUB
 Pyrexia - No pyrexia
 Hematuria - No hematuria
 Raised creatinine - Normal creatinine
 NSAIDs .
 Antispasmodics ?
 Alpha blockers
 Nefedipine ?
• Causes :
– Men:
• Benign prostatic enlargement (BPE) due to BPH
• Carcinoma of the prostate
• Urethral stricture
• Prostatic abscess
– Women
• Pelvic prolapse (cystocoele, rectocoele, uterine)
• Urethral stricture;
• Urethral diverticulum;
• Post surgery for ‘stress’ incontinence
• pelvic masses (e.g., ovarian masses)
Non traumatic
emergency
• Both Sex
– clot retention
– Drugs
– Pain
– Sacral nerve compression or damage(cauda equina
compression )
– Radical pelvic surgery
– Pelvic fracture rupturing the urethra
– Neurotropic viruses involving the sensory dorsal root
ganglia of S2–S4 (herpes simplex or zoster);
– Multiple sclerosis
– Transverse myelitis
– Diabetic cystopathy
– Damage to dorsal columns of spinal cord causing loss of
bladder sensation (tabes dorsalis, pernicious anaemia).
 Empty bladder – Distended bladder
Painful retention – Painless retention
 Raised creatinine – Normal creatinine
Pain + residual >400ml
needs drainage
 Do it immediately
 Urethral catheter 12/14F
 Record the residual
 Two attempts then call for help
 16F SPC if urethra impassable
 Obstruction develops slowly, the bladder
is distended (stretched) very gradually
over weeks/months, so pain is not a
feature .
 Presentation:
› Urinary dribbling
› Overflow incontinence
› Palpable lower suprapubic mass
Non traumatic
emergency
 Usually associated with
› Reduced renal function.
› Upper tract dilatation
 R/x is directed to renal support.
 Bladder drainage under slow rate to
avoid sudden decompression>
hematuria.
 Late R/x of cause.
 High Pressure CR
 Painless Incontinent
 Raised Cr
 Bilateral
hydronephrosis
 Catheterise
 Monitor output
 Check U&E
 Low Pressure CR
 Painless
 Dry
 Normal Cr
 Distended bladder
normal kidneys
 Do nothing
urgently!
Epididymitis
Torsion
Hydrocele
VaricoceleBlue
dot
sign
Torsio
n of
append
ix
epididy
mis
(A) extravaginal (B) intravaginal
 Can occur at any age
 Most common in adolescents
 Occasionally seen in neonates
 In infants & neonates the symptoms and
signs are imprecise
 Prompt action required to avoid
irreversible testicular ischemia
 Diagnosis
usually made
solely on basis
of clinical
examination
 It is high
 It is swollen
but
 Not necessarily
painful
 Color Doppler ultrasound:
› Assessment of anatomy and determining the
presence or absence of blood flow.
› Sensitivity: 88.9% specificity of 98.8%
› Operator dependent.
 If you have time Scrotal ultrasound scan
 If you don’t have time explore the
scrotum
You only have 6 hours
1
2
3
4
Minor twist-viable
Major twist- ? viable
Major twist-viable!
Major twist-necrotic
 Presentation:
 Indolent process.
 Scrotal swelling, erythema, and pain.
 Dysuria and fever is more common
 P/E :
› localized epididymal tenderness, a swollen and tender
epididymis, or a massively swollen hemiscrotum with
absence of landmarks.
› Cremasteric reflex should be present
 Urine:
› pyuria, bacteriuria, or a positive urine culture(Gram-
negative bacteria) .
Non traumatic
emergency
 Management:
› Bed rest for 1 to 3 days then relative
restriction .
› Scrotal elevation
› Parenteral antibiotic therapy
› Urethral instrumentation should be avoided
 Definition :
presence of blood in the urine.
 The passage of blood in the urine is
always alarming and investigation is
warranted.
Non traumatic
emergency
 Hematuria.
 Hemoglobinuria, myoglobinuia.
 Anthrocyanin in beets and blackberries.
 Chronic lead and mercury poisoning.
 Phenolphthalein (in bowel evacuants).
 Phenothiazines (compazine).
 Rifampicin.
MACROSCOPIC
MICROSCOPIC
SYMPTOMATIC
ASYMPTOMATIC
INITIAL
TERMINAL
TOTAL
 Microscopic examination :
 Urine dipsticks test :
-Urine dipsticks test for hem
(i.e. they test for presence of
hemoglobin & myoglobin in
urine ).
- Hem catalyses the oxidation
of orthotolidine by organic
peroxidase producing a blue
coloured compound.
-Dipsticks are capable of
detecting the presence of
hemoglobin from 1 or 2 RBCs.
 False positive results :
Myoglobinuria,
Bacterial peroxidases,
Povidine & hypochlorite.
• False negative results (rare):
Reducing agents ( e.g. ascorbic acid which
prevents oxidation of orthotolidine).
 Age and sex.
 Smoking.
 History of schistomiasis in endemic areas.
 Occupational exposure to carcinogens.
 Drugs e.g. NSAID, Cyclophosphamides.
 Pain, fever, dysuria, frequency.
 History of recent throat pain suggests post
infectious g.n.
 Information about exercise, menstruation, recent
catheterization or passage of calculi.
 Diagnoses
 Urothelial cancer
 UTI/STI
 Stone disease
 Decision
 Pain on voiding?
 Are there clots?
 Are they voiding?
Clinical/DRE
Temperature
Urinalysis
MSU/cytology
Bloods/PSA
IVU/UTUSS
Cystoscopy
Physiologic phimosis Pathologic phimosis Pathological
phimosis showing a
thickened indurated
phimotic band.
Non traumatic
emergency
Paraphimosis. Venous
return from the glans is impaired
and the prepuce is
edematous and engorged distal to
the phimotic ring
Sustained gentle
pressure is required
in order to reduce
the edematous
foreskin over the
glans
 The term “Priapism” is derived from
Priapus, the Greek god of fertility.
 An erection lasting longer than 4 h that is
not associated with sexual stimulation
Non traumatic
emergency
 Venous, low flow.
 Cessation of arterial
inflow serves to create
an acidotic and
hypoxic condition in
the penis.
 Increased
intracorporeal
pressure similar to the
compartment
syndrome.
 Arterial , high flow
 Unregulated arterial
inflow
 Ischemic  Non ischemic
 Idiopathic 50%.
 Intracavernosal inj.
 Antidepressant
Antipsychotics,
chlorpromazine,
phenothiazine.
 Antihypertensives ;
hydralazine, prazozine
 High fat content of TPN
 Cocaine and alcohol
 Direct trauma to penis,
perineum or pelvis
arterial rupture and
increased arterial
inflow.
 Ischemic  Non ischemic
 Sickle cell anemia.
 Leukemia.
 Neurologic :
lumber spinal stenosis,
cerebrovascular disease,
seizure disorders.
 Neoplasm: Ca bladder, Ca
prostate, metastatic renal
cell carcinoma
infiltrate and obstruct
venous drainage. (This type
of priapism is usually
treated with chemotherapy
or radiotherapy).
 Trauma to penis, perineum
or pelvis
arterial rupture and
increased intracorporeal
arterial inflow.
 Ischemic  Non ischemic
T
Aspiration of corporeal blood
For ABG
 Dark venous blood
 PH <7.25
 PO2 <30 mmHg
 PCO2 > 60 mm Hg
 CBC for leukemia
 Sickle C test
 Doppler U/S
 No cavernous arterial flow
 Bright arterial blood
 PH >7.3
 PO2 >50 mm Hg
 PCO2 < 40 mm Hg
 Ruptured cavernosal artery
with unregulated blood flow
pooling.
 Laboratory testing
 Ischemic
 Non ischemic
 History:
Duration and quality of erection .
Pain or no pain.
Medication and recreational drugs
Sickle cell anemia or hypercoagulable state.
 Physical examination :
- Rigid painful erection with a softer glans with
ischemic priapism
- Semirigid painless penis often with non ischemic
priapism
- Signs of genital or perineal trauma
- Signs of lymphadenopathy
 Penile nerve block : Inject lidocaine 1% at the
base of the penis at the 3 o’clock and 9 o’clock
positions.
 Insert an 18-gauge or 20-gauge butterfly needle into
one of the corpora cavernosa (2 o’clock or 10 o’clock
positions). Attach to a large syringe.
 Aspiration : Aspirate 50 mL (it may be necessary
to milk the penis). Dark blood is aspirated initially.
 If this does not lead to detumescence, then another 50
mL is aspirated from the contralateral corpus. Then
apply manual pressure to the penis for few minutes.
 Irrigation: If failure, then another 50 mL should
be aspirated from the corpora and irrigate
with 30–40 mL warm, sterile heparinised
saline solution (5000 U/L) and then aspirate
another 30–40 mL.
 Infusion: If failure, apply a tourniquet to the base of
the penis. Inject 200 μg of Phenylephrine (a1 agonist,
vasoconstrictor),50-100 μg Ephedrine, 20-80 μg Nor
adrenaline or 10-20 μg Adrenaline into the corpora.
Need to measure blood pressure, pulse rate every 5
minutes and to have electrocardiogram monitoring.
 Wait for 5–10 minutes; if this
fails, then repeat the
injection with another 200 μg
of phenylephrine. If this fails,
then consider another 500 μg
of phenylephrine.
If phenylephrine is not
available, then adrenaline 10–
20 μg every 5 minutes could
be used
 If failure, Surgery : Distal
shunt, if fails : Proximal
shunt
 1 Aspiration for diagnosis. Do not use
sympathomimetics
 2 Observation
 3 Embolization
 4 Surgery, aided by intraoperative Doppler
ultrasound
Blocked catheter
 Change the catheter don’t wash it out
 Send a CSU
 ? Start antibiotics
 Admit if pyrexial
Non traumatic
emergency
Urine bypassing the catheter
 Wash the bladder out
 Start anticholinergic drugs
Non traumatic
emergency
Non traumatic emergencies

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Non traumatic emergencies

  • 1.
  • 2.  Define common urological emergencies that may face non urologists.  How to diagnose these emergencies  Initial management of these problems for non urologists
  • 3. 1 Loin pain 2 Retention of urine 3 Testicular pain 4 Hematuria 5 Problems with the penis 6 Problems with catheters
  • 4.  Acute renal colic is the most excruciatingly painful event a person can endure . Non traumatic emergency
  • 5.  Does not always present with classic history  Classically presents with loin pain radiating around abdomen, as stone moves down ureter  May get testicular/labial pain +/- strangury if stone impacts at VUJ
  • 6. - Reflects the somatic sensory distribution of the spinal level of renal innervations - (T1o-T12). - Most probable hypothesis: Afferents from the skin & viscera converge on the same neuron in the spinal cord and share the same ascending neuron .
  • 7.  Urinalysis  CBC  BUN & s. Creatinine  KUB
  • 9.  Limitations  Significant obstruction may be associated with little dilatation of collecting system.  Relatively poor in visualizing the ureter.  Difficult to detect stones < 5mm in size  Operator and equipment dependent
  • 10.  95% sensitivity  98% specificity  Performed in 5 min.  Identifies radiolucent stones .  Identifies other causes of flank pain. stone
  • 11.  Treat the symptoms –analgesia  Blood cultures if pyrexial Consider antibiotics quinolone if not vomiting gentamicin if vomiting
  • 12.  Persistent pain .  Ureteral obstruction from a stone in a solitary or transplanted kidney .  Ureteral obstruction from a stone in presence of UTI, fever, sepsis or pyonephrosis.  Relative indication: Co morbid conditions (e.g. diabetes , dehydration, renal failure, or any immuno compromised state)
  • 13. Size of Stone < 4mm 4-6 mm > 6mm Management Conservative: 90% pass spontaneously 50% pass spontaneously – trial of passage Intervention likely, only 10% pass spontaneously
  • 14.  Stone on KUB - No stone on KUB  Pyrexia - No pyrexia  Hematuria - No hematuria  Raised creatinine - Normal creatinine
  • 15.  NSAIDs .  Antispasmodics ?  Alpha blockers  Nefedipine ?
  • 16.
  • 17. • Causes : – Men: • Benign prostatic enlargement (BPE) due to BPH • Carcinoma of the prostate • Urethral stricture • Prostatic abscess – Women • Pelvic prolapse (cystocoele, rectocoele, uterine) • Urethral stricture; • Urethral diverticulum; • Post surgery for ‘stress’ incontinence • pelvic masses (e.g., ovarian masses) Non traumatic emergency
  • 18. • Both Sex – clot retention – Drugs – Pain – Sacral nerve compression or damage(cauda equina compression ) – Radical pelvic surgery – Pelvic fracture rupturing the urethra – Neurotropic viruses involving the sensory dorsal root ganglia of S2–S4 (herpes simplex or zoster); – Multiple sclerosis – Transverse myelitis – Diabetic cystopathy – Damage to dorsal columns of spinal cord causing loss of bladder sensation (tabes dorsalis, pernicious anaemia).
  • 19.  Empty bladder – Distended bladder Painful retention – Painless retention  Raised creatinine – Normal creatinine
  • 20. Pain + residual >400ml needs drainage
  • 21.  Do it immediately  Urethral catheter 12/14F  Record the residual  Two attempts then call for help  16F SPC if urethra impassable
  • 22.  Obstruction develops slowly, the bladder is distended (stretched) very gradually over weeks/months, so pain is not a feature .  Presentation: › Urinary dribbling › Overflow incontinence › Palpable lower suprapubic mass Non traumatic emergency
  • 23.  Usually associated with › Reduced renal function. › Upper tract dilatation  R/x is directed to renal support.  Bladder drainage under slow rate to avoid sudden decompression> hematuria.  Late R/x of cause.
  • 24.  High Pressure CR  Painless Incontinent  Raised Cr  Bilateral hydronephrosis  Catheterise  Monitor output  Check U&E  Low Pressure CR  Painless  Dry  Normal Cr  Distended bladder normal kidneys  Do nothing urgently!
  • 25.
  • 27. (A) extravaginal (B) intravaginal
  • 28.  Can occur at any age  Most common in adolescents  Occasionally seen in neonates  In infants & neonates the symptoms and signs are imprecise  Prompt action required to avoid irreversible testicular ischemia
  • 29.  Diagnosis usually made solely on basis of clinical examination  It is high  It is swollen but  Not necessarily painful
  • 30.
  • 31.  Color Doppler ultrasound: › Assessment of anatomy and determining the presence or absence of blood flow. › Sensitivity: 88.9% specificity of 98.8% › Operator dependent.
  • 32.  If you have time Scrotal ultrasound scan  If you don’t have time explore the scrotum You only have 6 hours
  • 33.
  • 34. 1 2 3 4 Minor twist-viable Major twist- ? viable Major twist-viable! Major twist-necrotic
  • 35.
  • 36.  Presentation:  Indolent process.  Scrotal swelling, erythema, and pain.  Dysuria and fever is more common  P/E : › localized epididymal tenderness, a swollen and tender epididymis, or a massively swollen hemiscrotum with absence of landmarks. › Cremasteric reflex should be present  Urine: › pyuria, bacteriuria, or a positive urine culture(Gram- negative bacteria) . Non traumatic emergency
  • 37.  Management: › Bed rest for 1 to 3 days then relative restriction . › Scrotal elevation › Parenteral antibiotic therapy › Urethral instrumentation should be avoided
  • 38.
  • 39.  Definition : presence of blood in the urine.  The passage of blood in the urine is always alarming and investigation is warranted. Non traumatic emergency
  • 40.  Hematuria.  Hemoglobinuria, myoglobinuia.  Anthrocyanin in beets and blackberries.  Chronic lead and mercury poisoning.  Phenolphthalein (in bowel evacuants).  Phenothiazines (compazine).  Rifampicin.
  • 42.  Microscopic examination :  Urine dipsticks test : -Urine dipsticks test for hem (i.e. they test for presence of hemoglobin & myoglobin in urine ). - Hem catalyses the oxidation of orthotolidine by organic peroxidase producing a blue coloured compound. -Dipsticks are capable of detecting the presence of hemoglobin from 1 or 2 RBCs.
  • 43.  False positive results : Myoglobinuria, Bacterial peroxidases, Povidine & hypochlorite. • False negative results (rare): Reducing agents ( e.g. ascorbic acid which prevents oxidation of orthotolidine).
  • 44.  Age and sex.  Smoking.  History of schistomiasis in endemic areas.  Occupational exposure to carcinogens.  Drugs e.g. NSAID, Cyclophosphamides.  Pain, fever, dysuria, frequency.  History of recent throat pain suggests post infectious g.n.  Information about exercise, menstruation, recent catheterization or passage of calculi.
  • 45.  Diagnoses  Urothelial cancer  UTI/STI  Stone disease  Decision  Pain on voiding?  Are there clots?  Are they voiding? Clinical/DRE Temperature Urinalysis MSU/cytology Bloods/PSA IVU/UTUSS Cystoscopy
  • 46. Physiologic phimosis Pathologic phimosis Pathological phimosis showing a thickened indurated phimotic band. Non traumatic emergency
  • 47. Paraphimosis. Venous return from the glans is impaired and the prepuce is edematous and engorged distal to the phimotic ring Sustained gentle pressure is required in order to reduce the edematous foreskin over the glans
  • 48.  The term “Priapism” is derived from Priapus, the Greek god of fertility.  An erection lasting longer than 4 h that is not associated with sexual stimulation Non traumatic emergency
  • 49.  Venous, low flow.  Cessation of arterial inflow serves to create an acidotic and hypoxic condition in the penis.  Increased intracorporeal pressure similar to the compartment syndrome.  Arterial , high flow  Unregulated arterial inflow  Ischemic  Non ischemic
  • 50.  Idiopathic 50%.  Intracavernosal inj.  Antidepressant Antipsychotics, chlorpromazine, phenothiazine.  Antihypertensives ; hydralazine, prazozine  High fat content of TPN  Cocaine and alcohol  Direct trauma to penis, perineum or pelvis arterial rupture and increased arterial inflow.  Ischemic  Non ischemic
  • 51.  Sickle cell anemia.  Leukemia.  Neurologic : lumber spinal stenosis, cerebrovascular disease, seizure disorders.  Neoplasm: Ca bladder, Ca prostate, metastatic renal cell carcinoma infiltrate and obstruct venous drainage. (This type of priapism is usually treated with chemotherapy or radiotherapy).  Trauma to penis, perineum or pelvis arterial rupture and increased intracorporeal arterial inflow.  Ischemic  Non ischemic T
  • 52. Aspiration of corporeal blood For ABG  Dark venous blood  PH <7.25  PO2 <30 mmHg  PCO2 > 60 mm Hg  CBC for leukemia  Sickle C test  Doppler U/S  No cavernous arterial flow  Bright arterial blood  PH >7.3  PO2 >50 mm Hg  PCO2 < 40 mm Hg  Ruptured cavernosal artery with unregulated blood flow pooling.  Laboratory testing  Ischemic  Non ischemic
  • 53.  History: Duration and quality of erection . Pain or no pain. Medication and recreational drugs Sickle cell anemia or hypercoagulable state.  Physical examination : - Rigid painful erection with a softer glans with ischemic priapism - Semirigid painless penis often with non ischemic priapism - Signs of genital or perineal trauma - Signs of lymphadenopathy
  • 54.  Penile nerve block : Inject lidocaine 1% at the base of the penis at the 3 o’clock and 9 o’clock positions.  Insert an 18-gauge or 20-gauge butterfly needle into one of the corpora cavernosa (2 o’clock or 10 o’clock positions). Attach to a large syringe.  Aspiration : Aspirate 50 mL (it may be necessary to milk the penis). Dark blood is aspirated initially.  If this does not lead to detumescence, then another 50 mL is aspirated from the contralateral corpus. Then apply manual pressure to the penis for few minutes.
  • 55.  Irrigation: If failure, then another 50 mL should be aspirated from the corpora and irrigate with 30–40 mL warm, sterile heparinised saline solution (5000 U/L) and then aspirate another 30–40 mL.  Infusion: If failure, apply a tourniquet to the base of the penis. Inject 200 μg of Phenylephrine (a1 agonist, vasoconstrictor),50-100 μg Ephedrine, 20-80 μg Nor adrenaline or 10-20 μg Adrenaline into the corpora. Need to measure blood pressure, pulse rate every 5 minutes and to have electrocardiogram monitoring.
  • 56.  Wait for 5–10 minutes; if this fails, then repeat the injection with another 200 μg of phenylephrine. If this fails, then consider another 500 μg of phenylephrine. If phenylephrine is not available, then adrenaline 10– 20 μg every 5 minutes could be used  If failure, Surgery : Distal shunt, if fails : Proximal shunt
  • 57.  1 Aspiration for diagnosis. Do not use sympathomimetics  2 Observation  3 Embolization  4 Surgery, aided by intraoperative Doppler ultrasound
  • 58.
  • 59. Blocked catheter  Change the catheter don’t wash it out  Send a CSU  ? Start antibiotics  Admit if pyrexial Non traumatic emergency
  • 60. Urine bypassing the catheter  Wash the bladder out  Start anticholinergic drugs Non traumatic emergency

Editor's Notes

  1. Fowler’s syndrome (impaired relaxation of external sphincter occurring in premenopausal women, often in association with polycystic ovaries
  2. Haematuria leading to clot retention Drugs: anticholinergics, sympathomimetic agents such as ephedrine in nasal decongestants Pain (adrenergic stimulation of the bladder neck) postoperative retention; sacral (S2–S4) nerve compression or damage—so-called cauda equina compression (due to prolapsed L2–L3 disc or L3–L4 intervertebral disc, trauma to the vertebrae, benign or metastatic tumours) radical pelvic surgery damaging the parasympathetic plexus (radical hysterectomy, abdominoperineal resection); pelvic fracture rupturing the urethra (more likely in men than women); neurotropic viruses involving the sensory dorsal root ganglia of S2–S4 (herpes simplex or zoster); multiple sclerosis transverse myelitis diabetic cystopathy Damage to dorsal columns of spinal cord causing loss of bladder sensation (tabes dorsalis, pernicious anaemia).