Acute scrotal pain can be caused by many conditions, but the most common are testicular torsion and epididymitis. A thorough clinical examination is important to distinguish between these and other causes like trauma. Testicular torsion is a urological emergency requiring urgent surgical intervention, as delayed treatment can result in loss of the testis. Epididymitis is usually treated with antibiotics as an outpatient. Ultrasound is useful to confirm diagnoses and determine if surgical intervention is needed.