Nano-bio Dr Nedra Karunaratne
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This document discusses various applications of nanotechnology in biology and medicine, including fluorescent biological labels, MRI contrast enhancement, biodetection of pathogens, detection of proteins, separation and purification of biomolecules and cells, probing of DNA structure, tumour destruction via heating, tissue engineering, biosensors, biomineralization, and drug and gene delivery. Quantum dots are discussed as an example of fluorescent biological labels. Carbon nanotubes have potential uses as nanoelectrodes, in lab-on-a-chip applications, DNA sequencing, artificial muscles, and vision chips. Commercial exploration of nanotechnology includes uses in toothpaste, cell separation, luminescent biomarkers, MRI shielding, implants, and drug/gene delivery.
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The document discusses the concept of an "Internet of Bio-Nano Things" (IOBNT), which envisions integrating nanotechnology with biological systems to create networks of devices that sense and interact with their environments. An IOBNT would consist of bio-nanosensors and biocompatible nanomachines that could operate within living organisms. These nanodevices would have processors, memory, chemical receptors, and other components similar to cells and organelles. They could potentially be used to precisely monitor physiological processes and health metrics in real-time. The document outlines some of the technical challenges and opportunities of developing an IOBNT to revolutionize healthcare, environmental monitoring, and other fields.
CZECH NANO SHOW - David Lukas - TUL
The document discusses the Technical University of Liberec in the Czech Republic. It notes that the university has several faculties including Mechanical Engineering, Textile Engineering, Economics, Education, and Mechatronics. It also has an Institute of Nanomaterials, Advanced Technologies and Innovations. The document references a 2005 patent by Jirsák et al. on a method of producing nanofibers from a polymer solution using electrostatic spinning. It also briefly mentions AC electrospinning and thanks the audience for their attention before listing additional contact names and providing a website link.
Nanotechnology in biological applications
Width = 0.1 mm. The document discusses various applications of nanotechnology in fields such as lifestyle, health, technology, environment, textiles, shelter, agriculture and food, transportation, and medicine. By 2020, $1 trillion worth of devices will be nano-engineered. Nanotechnology is beginning to revolutionize industries such as electronics, computing, medicine, cosmetics, food, energy generation, and the military.
Nano-electronics
This presentation is about the emerging and future possible trends of the exciting field of nanotechnology. Scientists and engineers are working on a smaller scale day-by-day to increase portability and smaller devices, and to change the way we see the world and live in!
Graphite,Fullerene And Carbon Nanotubules
A short presentation on Graphite,Fullerene And Carbon Nanotubules. Its consists of structures, preparation and properties. Hope you'll like it.
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The document discusses carbon nanotube (CNT)/epoxy matrix nanocomposites. It notes that dispersing CNTs homogeneously in the epoxy matrix is important to exploit their potential but is difficult due to aggregation. Methods to improve dispersion include using surfactants or functionalizing CNTs. Functionalization can degrade CNT properties so alternative methods are sought. The properties of CNT/epoxy nanocomposites depend on the degree of CNT dispersion, with higher conductivity achieved above the percolation threshold.
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Carbon nanotubes (cnt) as interconnects for future
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The document discusses the application of nanotechnology in biosensors. It begins by defining nanotechnology and biosensors. Nanoparticles are gaining interest in biosensing applications due to their size-dependent properties. Standard procedures for detection are time-consuming, non-specific, costly, and require trained personnel. Nanoparticles can be used to develop micro/nanobiosensors that are fast, inexpensive, simple to use, efficient, and portable. Various types of nanoparticles and detection techniques using nanoparticles like fluorescence, inductively coupled plasma mass spectrometry, and potentiometric analysis are then described.
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This document discusses various nanotechnology approaches for cancer diagnosis, including the use of gold nanoparticles, quantum dots, carbon nanotubes, and nanoflares. Gold nanoparticles can be used for detection through techniques like dynamic light scattering and surface plasmon coupling. Quantum dots and carbon nanotubes can also be functionalized for ultrasensitive detection of cancer biomarkers. Emerging tools like nanoflares allow for detection of genetic targets associated with cancer within living cells. Overall, nanotechnology enables low detection limits and early cancer diagnosis.
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Principles of Nanobiotechnology. ppt.ppt
Nanobiotechnology uses nanotechnology to analyze and engineer biological systems at the nanoscale level. The document provides an overview of key concepts in nanobiotechnology including:
- Nanoparticles which are between 1-100 nm and have unique physical and chemical properties compared to larger particles.
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Week 9 - lecture 8.pptx
This document discusses topics that will be covered in a course on nanobiosensors, including the history and applications of biosensors, principles of molecular recognition and signal transduction, sources and design of biological recognition elements, modeling of reactions for various biosensor applications, modification of sensor surfaces and immobilization techniques, detection methods and physical sensors, fabrication of biosensors, and data acquisition and analysis. Examples of commercial biosensors and recent developments in new-generation nano-engineered biosensors are also mentioned.
Luminescent materials for biomedical applications: the example of nanothermom...
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Plenary lecture of the XIII SBPMat (Brazilian MRS) meeting, given on September 29th 2014 by Prof. Luís Carlos Dias (Universidade de Aveiro, Portugal).Priya application of quantum dots in biological sciences
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nano imaging its potential and future.pptx
This document provides an introduction to bionanoimaging. It discusses various nanoimaging techniques such as scanning probe microscopy, transmission electron microscopy, and scanning electron microscopy. It also discusses different materials used in nanoimaging like quantum dots, which can be tuned to emit specific wavelengths of light depending on their size. New approaches in nanoimaging include using contrast agents for ultrasound imaging to overcome limitations of traditional ultrasound and achieve improved resolution for deeper scans. Applications of nanoimaging span various fields like materials science, biology, medicine, electronics, and nanotechnology.
Nanoparticles and sensors applications
Nanoparticles and sensors applicationsMinal Saini , student of Chaudhary bansilal University , Bhiwani, Haryana
Nanoparticles between 1-100 nanometers are used in sensors due to their optical properties. Silver nanoparticles are commonly used due to higher extinction coefficient and biological properties. Nanoparticle sensors can detect biological, chemical, or surgical information on a microscopic level due to their small size. They interact with light and exhibit surface plasmon resonance, enhancing local electromagnetic fields. Nanoparticle sensors have applications in medicine, national security, aerospace, and more. Challenges remain in reducing costs, improving reliability, and mass production.Nanobiotechnology
Nanobiotechnology involves manipulating structures at the nanoscale (1-100nm) using biological components. Some applications include faster disease diagnostics using biosensors, more targeted drug delivery using nanoparticles, and miniaturizing lab tools. Nanoparticles are typically spherical and composed of functional, protective, and outer layers. They can be used for fluorescent labeling, detecting pathogens, and delivering drugs or genes. Nanowires and nanotubes can also be used as biosensors to detect individual viruses or changes in conductivity when pathogens bind.
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The revolution of nanotechnology in molecular biology gives an opportunity to detect and manipulate atoms and molecules at the molecular and cellular level.
Nanosensors
A part of nanotechnology. Nanosensors is very hot topic for research. As nanosensor has immense applications in the fields like medical, analysis, research etc. Nanosensor recude the cost and also the time require for analysis.
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role of nanotechonolgy in diagnostic pathology.pptx
Nanotechnology involves engineering materials and devices on the nanoscale (1-100 nm) and can be applied to diagnostic pathology. It allows for early disease detection by taking advantage of nanoparticles' high surface area and ability to interact with biomolecules. Common nanodiagnostic techniques include magnetic nanoparticles for MRI contrast, nanochips for DNA analysis, microfluidics to automate biochemical assays, and nanoarrays for high-throughput screening of proteins and nucleic acids. Future applications may integrate multiple functions like imaging, detection, targeted drug delivery, and treatment monitoring into single nanodevices.
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“Building and Scaling AI Applications with the Nx AI Manager,” a Presentation...Edge AI and Vision Alliance
For the full video of this presentation, please visit: https://www.edge-ai-vision.com/2024/06/building-and-scaling-ai-applications-with-the-nx-ai-manager-a-presentation-from-network-optix/
Robin van Emden, Senior Director of Data Science at Network Optix, presents the “Building and Scaling AI Applications with the Nx AI Manager,” tutorial at the May 2024 Embedded Vision Summit.
In this presentation, van Emden covers the basics of scaling edge AI solutions using the Nx tool kit. He emphasizes the process of developing AI models and deploying them globally. He also showcases the conversion of AI models and the creation of effective edge AI pipelines, with a focus on pre-processing, model conversion, selecting the appropriate inference engine for the target hardware and post-processing.
van Emden shows how Nx can simplify the developer’s life and facilitate a rapid transition from concept to production-ready applications.He provides valuable insights into developing scalable and efficient edge AI solutions, with a strong focus on practical implementation.AI 101: An Introduction to the Basics and Impact of Artificial Intelligence
Imagine a world where machines not only perform tasks but also learn, adapt, and make decisions. This is the promise of Artificial Intelligence (AI), a technology that's not just enhancing our lives but revolutionizing entire industries.
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AI 101: An Introduction to the Basics and Impact of Artificial Intelligence
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Nano-bio Dr Nedra Karunaratne
- 1. Nanotechnology applications in Biology and Medicine Prof. Nedra Karunaratne
- 2. Applications of nanomaterials in biology Fluorescent biological labels MRI contrast enhancement Biodetection of pathogens Detection of proteins Separation and purification of biomolecules and cells. Probing of DNA structure Tumour destruction via heating (hyperthermia) Phagokinetic studies Tissue engineering Biosensors- Enzyme Electronic biosensors, etc. Biomineralization Drug and gene delivery-( later under DDM and encapsulation) Ref. OV Salata. Journal of Nanobiotechnology 2004, 2:3
- 3. Fluorescent biological labels- Quantum Dots Ten distinguishable emission colours of ZnS capped CdSe Quantum Dots excited with a near UV lamp. From left to right (blue to red, emission maxima are 443, 473, 481,500, 518, 543, 565, 587, 610 qnd 655nm.
- 4. Antigen/Antibody Immunocomplex from CdTe Nanoparticle Bioconjugates. Nano Letters, 2 (2002) 817 - 822 Change in the colour when antigen binds the antibody
- 5. For optical measurements near IR ,UV & fluorescence emission properties are mostly considered. IR,UV & fluorescence detectors are used as instruments Biophoton emission of AH109A, a rat hepatoma, with 107cells transplanted into BALB-c nu/nu mice. Fluorescence of nanoparticles Fluorescence detection
- 6. Biodetection of Pathogens by DNA Hybridization A multianalyte biosensor that uses DNA hybridization, magnetic micro beads and giant magnetoresistive (GMR) sensors to detect and identify biological warfare agents. (BARC bead array counter)
- 7. Schematic diagram of the BARC chip surface chemistry and hybridization assay. Thiolated DNA probes are patterned onto a gold layer directly above the GMR sensors on the BARC chip. Biotinylated sample DNA is then added and hybridizes with the DNA probes on the surface when the complementary sequence is present. Unbound sample DNA is washed away. Streptavidin coated magnetic beads are injected over the chip surface, binding to biotinylated sample DNA hybridized on the BARC chip. Beads that are not specifically bound are removed by applying a magnetic field. Bound beads are detected by the GMR sensors.
- 8. Applications of Carbon nanotubes. • CNT based microscopy: AFM, STM… • Nanotube sensors: bio, chemical… • Nanoscale reactors, ion channels • Biomedical - Nanoelectrodes for implantation - Lab on a chip - DNA sequencing through AFM imaging - Artificial muscles - Vision chip for macular degeneration, retinal cell transplantation
- 9. 3+ 2+ e 3+ 2+ Probe molecules for a given target can be attached to CNT tips for biosensor development Electrochemical approach: requires nanoelectrode development using PECVD grown vertical nanotubes The signal can be amplified with metal ion mediator oxidation CNT Biosensors
- 10. Functionalized nanotubes: Molecular structures of derivatised carbon nanotubes- derivative (1) and mono (2) and bis (3) conjugates. Ref. Chemistry & Biology 10 (2003) 961 - 966 Applications- Biological labelling, cancer diagnostics, Gene identification
- 11. Fabrication of Gene chip Potential applications: (1)Lab-on-a-chip applications (2)Early cancer detection (3)Infectious disease detection (4)Environmental monitoring (5)Pathogen detection
- 12. Commercial Exploration- Advectus Life Science Inc Drug Delivery BASF Toothpaste Immunicon Cell Separation Evident Technol, Quantum Dot Corp. Luminescent biomarkers Nanoprobes Inc. Gold nanoparticles Biophan Technologies Inc. MRI Shielding Argonide Membrane filtration Enviro Systems Inc. Surface Disinfectants PSiVida Ltd. Tissue Engineering,implants, drugs and gene delivery, bio-filtration. Smith & Nephew Acticoat bandages
- 13. Way ahead Fabrication of bioindicators for detection of tropical diseases. (early detection of Malaria, Denghi, Leptospirosis etc) Gene chip Membrane filtration (applications in water purification eg for CKDu patients) Diagnostic kits. (detecting glucose and other metabolites) Delivery of nutrients in food (nanodelivery systems) and agricultural (fertilizer) applications Applications in drug delivery (discussed separately)