Biofilm inoculants and rhizobial inoculants are types of biofertilizers that can replace chemical fertilizers for certain crops. Studies showed that biofilm biofertilizers can replace 50% of nitrogen, phosphorus, and potassium chemical fertilizers without reducing yields of various crops including tea, rice, maize, and strawberries. Rhizobial biofertilizers can replace 100% of chemical nitrogen fertilizers without impacting yields of legumes like soybeans, vegetable beans, cowpeas, and mung beans. The conclusions indicate that biofertilizers are effective alternatives to partially or fully substitute for chemical fertilizers.