This document provides information about cosmetic preparations for nail polish, including nail lacquers, enamel removers, and recent advances. It defines nail lacquers and lists their ideal characteristics. The key components of nail lacquer formulations are described, including film formers, resins, solvents, plasticizers, and coloring agents. The manufacturing process and evaluation of nail lacquers is also summarized. Different types of enamel removers and their formulations are outlined. The document concludes with details about a pharmaceutical nail lacquer for fungal infections and some recent advances in nail care products.
Manicure preparations - nail polishes, nail enamel removers, nail art (definitions, formulations, method of preparation, pictures, evaluations) Dosage form
Shampoo
Human Hair Structure
Introduction
Shampoo is a hair care product that is used for the removal of oils, dirt, skin particles, dandruff, environmental pollutants and other contaminant particles that gradually build up in hair.
Introduction
Ideal Properties
Functions of Shampoo
Classification
Classification
Based on Appearance:
Powder Shampoos
Liquid Shampoos or Lotion
Gel Shampoos or Solid Cream
Classification
Classification
II. Based on Use or Function:
Conditioning Shampoos
Antidandruff and Therapeutic
Baby
Balancing
Clarifying
Classification
III. Based on Origin:
Compositions
Shampoos are typically composed of 10 to 30 ingredients.
Several types of ingredients are particularly important, including “Surfactants" that aid in cleansing and lathering.
“Conditioners" and “Active ingredients" that affect the hair and scalp.
“Additives" that stabilize the product.
Compositions
Compositions
Compositions
Compositions
Manufacturing Process
Some pearlising agents are waxy solids at ambient temperature and require melting in a drum oven or similar before use.
Demineralised water is most commonly used in order to minimise contamination of the product.
No further processing is required after blending, and the product may be packed off directly from the mixing vessel.
Manufacturing Process
For preparing liquid shampoo,
Triethanalamine lauvyl sulfate,
stearic acid are heated to about 650C.
Water & preservatives are also heated to 650C.
Both the solutions are mixed together and then cooled.
Perfumes are added after that. The shampoo thus prepared is bottled by automatic bottle filling machine.
Quality Control Tests
a)Foam Stability
Cylinder shake method was used for determining foaming ability.
50ml of the 1% shampoo solution was put into a 250ml graduated cylinder and cover the cylinder with hand and shaken for 10 times. The total volumes of the foam contents after 1 minute shaking were recorded. The foam volume was calculated. Foam should retain for atleast 5mins.
Foam Stability = V2-V1
Quality Control Tests
b)Skin – irritation Test:
Draize test in Rabbits where a patch test technique is used on the intact skin of Albino Rabbits.
A set of 6Rabbits used for testing each material.
Shampoos should be tested only for a short duration thatis,not more than(NMT)4hours as these products come in contact with skin only for a short duration.
These preparations are diluted between concentrations of 8 to 10%.
Quality Control Tests
c)Wetting Action:
Canvas disk is used, is one inch in diameter is floated on the surface of a solution and the time required for it to sink is measured accurately.
Quality Control Tests
d)Viscosity:
Is determined using Brookefield Viscometer.
100ml of shampoo is taken in a beaker and spindle is dipped in it for about 5min and then reading is taken.
Quality Control
COSMETICS CLASSIFICATION By Tannu SainiTannuSaini4
Classification of Cosmetics -
Can be classified based on widely used body parts as:
Skin cosmetics
Hair cosmetics
Face cosmetics
Eye make ups
Lip decorators & carers
Nail cosmetics
Manicure preparations - nail polishes, nail enamel removers, nail art (definitions, formulations, method of preparation, pictures, evaluations) Dosage form
Shampoo
Human Hair Structure
Introduction
Shampoo is a hair care product that is used for the removal of oils, dirt, skin particles, dandruff, environmental pollutants and other contaminant particles that gradually build up in hair.
Introduction
Ideal Properties
Functions of Shampoo
Classification
Classification
Based on Appearance:
Powder Shampoos
Liquid Shampoos or Lotion
Gel Shampoos or Solid Cream
Classification
Classification
II. Based on Use or Function:
Conditioning Shampoos
Antidandruff and Therapeutic
Baby
Balancing
Clarifying
Classification
III. Based on Origin:
Compositions
Shampoos are typically composed of 10 to 30 ingredients.
Several types of ingredients are particularly important, including “Surfactants" that aid in cleansing and lathering.
“Conditioners" and “Active ingredients" that affect the hair and scalp.
“Additives" that stabilize the product.
Compositions
Compositions
Compositions
Compositions
Manufacturing Process
Some pearlising agents are waxy solids at ambient temperature and require melting in a drum oven or similar before use.
Demineralised water is most commonly used in order to minimise contamination of the product.
No further processing is required after blending, and the product may be packed off directly from the mixing vessel.
Manufacturing Process
For preparing liquid shampoo,
Triethanalamine lauvyl sulfate,
stearic acid are heated to about 650C.
Water & preservatives are also heated to 650C.
Both the solutions are mixed together and then cooled.
Perfumes are added after that. The shampoo thus prepared is bottled by automatic bottle filling machine.
Quality Control Tests
a)Foam Stability
Cylinder shake method was used for determining foaming ability.
50ml of the 1% shampoo solution was put into a 250ml graduated cylinder and cover the cylinder with hand and shaken for 10 times. The total volumes of the foam contents after 1 minute shaking were recorded. The foam volume was calculated. Foam should retain for atleast 5mins.
Foam Stability = V2-V1
Quality Control Tests
b)Skin – irritation Test:
Draize test in Rabbits where a patch test technique is used on the intact skin of Albino Rabbits.
A set of 6Rabbits used for testing each material.
Shampoos should be tested only for a short duration thatis,not more than(NMT)4hours as these products come in contact with skin only for a short duration.
These preparations are diluted between concentrations of 8 to 10%.
Quality Control Tests
c)Wetting Action:
Canvas disk is used, is one inch in diameter is floated on the surface of a solution and the time required for it to sink is measured accurately.
Quality Control Tests
d)Viscosity:
Is determined using Brookefield Viscometer.
100ml of shampoo is taken in a beaker and spindle is dipped in it for about 5min and then reading is taken.
Quality Control
COSMETICS CLASSIFICATION By Tannu SainiTannuSaini4
Classification of Cosmetics -
Can be classified based on widely used body parts as:
Skin cosmetics
Hair cosmetics
Face cosmetics
Eye make ups
Lip decorators & carers
Nail cosmetics
Nail Products are products that are used to color the nails, to protect them against damage, to soften and condition cuticles, and to supplement the nails. They include nail polish and enamels and nail polish and enamel removers.
Fabric softener (also called fabric conditioner) is used to prevent static cling and make fabric softer i.e. Softening agents are applied to textiles to improve their hand, drape, cutting and sewing qualities.Fabric softeners work by coating the surface of the cloth fibers with a thin layer of chemicals; these chemicals have lubricant properties and are electrically conductive, thus making the fibers feel smoother and preventing buildup of static electricity
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
1. COSMETIC PREPARATIONS FOR NAIL POLISH
PRESENTED BY:
L.GOPI M.PHARM FIRST YEAR
AADHI BHAGAWAN COLLEGE OF
PHARMACY
RANTHAM
GUIDED BY:
Dr.V.KALVIMOORTHY M.PHARM.,PhD
PROF OF DEPARTMENT OF
PHARMACEUTICS
AADHI BHAGAWAN COLLEGE OF
PHARMACY
RANTHAM
2. INTRODUCTION
• Nails are transparent protective coverings on finger tips and toes of feet.
• The care of nails is referred to as Manicuring .
• Manicure preparations include:
• Nail lacquer/enamel/paint/varnish
• Enamel remover
• Powder polish
• Nail cream
• Nail bleach
• Cuticle remover
• Cuticle softener
3. NAIL LACQUERS
• Definition :
• “Nail lacquers are viscous preparations intended
• to decorate nails for fingers and toes”.
• Ideal Characteristics:
• It should have proper viscosity wetting and flow
properties.
• It should have uniform colour.
• It should have good gloss and good adhesive properties.
4. • It should have sufficient flexibility so that it does not
crack or become brittle.
• It should have sufficient hard surface which is resistant
to impact and scratch.
• It should have reasonable drying time (1-2 minutes)
without developing bloom.
• It should be able to maintain the above mentioned
properties for a reasonable time (about 1 week ).
5. Classification:
Pearled nail lacquers:
• Made up of lacquer base, colourants, pearl
essence.
Creamy nail lacquers:
• Made up of a lacquer base, organic and
inorganic pigments.
6. Formulation:
Lacquer base
1. Film former
2. Resin
3. Solvent
4. Plasticizer
Colouring agents
1. Dyes
2. Lakes
3. Pigments
4. Pearl essence
8. Film formers:
Impart hardness, toughness, resistance to abrasion ,
viscosity to some extent.
Nitrocellulose-widely used , based on viscosity ,
SR nitrocellulose :10.7 to 11.2% N2
RR nitrocellulose :11.2 to 12.8% N2
Other examples include cellulose acetate , cellulose
acetate butylate, ethyl cellulose, vinyl polymers and various
polymers of methacrylate.
9. Resins:
• It impart adhesion and improve gloss , help in
dispersing insoluble pigments and lakes.
• Natural resins :Shellac, benzoin, gum dammar,
sandarac, ester gums.
• Synthetic resins: Sulphonamide-formaldehyde resins
(poly aryl sulphonamides).
Commercial resins :
• SantoliteMHP : Claimed to Increase hardness of
nitrocellulose and impart gloss to it.
• SantoliteMS 80% : Claimed to increase moisture
resistance.
10. Solvents:
•Solvents are volatile organic liquids that combine all the
ingredients of lacquer formulation and make a
homogeneous viscous preparation.
•Impart brushabilityand for regulating its drying time ,
viscosity of the preparation.
•High BP-gives a brighter film .
•Low BP-Lowers viscosity and covering power.
•Solvents are in 3 inter-related categories:
1. Active solvents: True solvents
•Eg., esters, ketonesand glycol ethers for Nitrocellulose.
11. 2.Couplers:
• Not solvents but in conjugation increase the strength of
other solvents.
3.Diluents:
• Diluents are non-solvents for nitrocellulose . These are
used to stabilize viscosity, to carry resins in solution and
to reduce the effect of subsequent applications on the
coat of enamel already applied, to lower the overall cost
of the product.
• Eg., Aromatic and aliphatic hydrocarbons and alcohols
like Toulene, benzene, xylene, hexane, heptanes,
naphthas, light petroleum ether.
12. Plasticizer:
• They impart flexibility and adhesiveness to the film , and
also effect viscosity and the volatility or rate of drying .
• Two types of plasticizers:
• Solvent plasticizers: Act as solvents and are of high
molecular weight.
• Eg., Butyl acetyl ricenoleate
.
• Non-Solvents plasticizers: Act as a softener.
• Eg.,Castoroil.
13. Colouringagents:
• Impart acceptable shade to the lacquer base .
• The colouringagents must comply with the terms of Drug
and Cosmetic act , should disperse well , be resistant to
light , acids and alkali found in detergents , be non-
staining and produce a good gloss.
• Dyes:Soluble dyes alone normally cannot impart
sufficient depth of colour,abandoned due to staining the
surface & surroundings of the nail. Eg., Eosin,
erythrosine, carmosine, rhodamine
• Lakes:Insolublelakes are incorporated to produce
suitable shades.
• Eg., Colourlakes mentioned in Schedule Q to Drug and
Cosmetics Act rules.
14. Other formulating agents:
•Suspending agents: Suspendingproperties have been
achieved by developing thixotropicsystem using pre-heated
colloidal clays.
•Eg., Benzyl dimethylhydrogenated tallow
Ammonium montmorillonite(Bentone27)
Dimethyldioctadecylammonium bentonite(Bentone34)
•Opacifyingagents:Theseare whitening agents which help to
develop shades which will reflect the same colouron the nails as
they are in the bottle. Eg., Titanium dioxide, Zinc oxide.
•UV absorbers: To prevent deterioration of ingredients due to UV
light .
•Eg., Benzophenonesand its derivatives.
•Perfume: used mainly to counteract the unpleasant odourof the
solvents .
•Eg.,Syntheticperfumes are preferred.
15. Formulation of a Pearlescent Nail lacquer
Ingredients %
Nitrocellulose 14.90
Butyl acetate 34.04
Toulene30.00
Toulenesulphonamideformaldehyde resin 7.10
Dibutyl phthalate 4.80
Camphor 2.40
Stearyl konium hectorite 1.20
Benzophenone - 10.20
D & C Red No. 7 , Calcium lake 0.08
D & C , No. Red . No.34 , Calcium Lake 0.05
FD&C,No.5,Aluminium lake 0.08
Bismuth oxychloride (25%) 5.00
Iron oxides 0.15
17. FILLING:
• Since nail lacquers are highly inflammable, filling,
capping and packing must be carried out under fire-proof
and explosion-proof conditions.
• Proper care and precautions should be followed, for
example, good ventilation, proper electrical wiring and
prohibition of cigarette smoking in the working area.
18. PACKING & LABELLING:
• Glass bottles with a brush applicator is the most
conventional container which is used for the packaging
of nail lacquers.
• The capacity varies from 8ml to 18ml .
• The applicator consists of an air-tight aluminium canister
with an acrylic fiber tip or nib which applies polish directly
to nails.
19. Evaluation :
• Before nail lacquer is packed , the following testsshould be
carried out as a measure of quality control :
• Colour matching
• Drying rate
• Non-volatile content
• Smoothness
• Gloss
• Hardness
• Application properties
• Abrasion resistance
• Adhesion
• Water resistance
• Viscosity
• Stability
20. ENAMEL REMOVERS:
Definition:
•Nail removers / nail cleansers are defined as the mixture of
solvents containing small amounts of fat intended to remove the
nail enamel.
Ideal Characteristics:
An ideal lacquer remover should have the following
characteristics :
•It should not be too volatile to evaporate during application.
•It should not be non-irritating to surrounding skin.
•It should not leave the nails fatty or sticky.
•It should not have strong degreasing effect to leave nails brittle.
•It should not have unpleasant and obstrusive odour.
21. Types and formulation of
Enamel Removers:
Type I contains solvent blends and a small percentage of
oily materials.
•Formula :
Ingredients %
Castor oil 2.5
Diethyleneglycol mono ethyl ether 14.5
Acetone 83.0
22. • Type 2 (Non smearing enamel) contains Water and
water miscible solvents.
• Formula :
Ingredients %
Water 10.0
Ethyl acetate 90.0
• Method of preparation :
A simple remover prepared by mixing water and ethyl
acetate.
23. •Type 3 ( Cream type enamel remover) contains solvent, waxes
and soap.
• Formula :
Ingredients %
Bees wax 3.0
Micro-crystalline wax 1.0
Acetylated monoglycerides 10.0
Diethylene glycol monoethyl ether 52.0
Ethyl acetate 15.0
Stearic acid 15.0
Triethanolamine 4.0
• Method of preparation :
Melt all ingredients except triethanolamine , add triethanolamine
to the mixture with stirring and allow to cool.
24. • Type 4 (Gel type varnish remover) contains
hydroxypropylcellulose.
• Formula :
Ingredients %
Hydroxypropylcellulose 1.0
Butyrolacetone 75.0
PPG-12-PEG-50 lanolin 1.0
Pigment (in Butyrolacetone) 0.1
Sodium hydroxide (5% aqueous) q.s
Water To make 100.0
25. •Type 5 ( Conditioning nail polish remover) contains
Malleated Soyabean oil and acetone.
•Formula :
Ingredients %
MalleatedSoyabeanoil 10.0
Acetone 90.0
• Method of preparation :
Simple mixing of oil in the solvent.
26. Evaluation of nail enamel remover:
•Subjects were given a supply of the test nail polish
remover, nail enamel and cotton pads, along with
instructions for use and a diary.
•Subjects were instructed to remove their nail enamel
using the test product provided, 3 times per week for 4
weeks for a total of 12 uses.
•Subjects were instructed to use their usual brand of
hand care products and not to introduce the use of any
new hand care or nail products for the duration of the
study.
•Subjects returned after 4 weeks of use for a final
evaluation of the cuticles for signs of irritation. The last
use of the test product was within 24 hours of the final
product.
27. Pharmaceutical nail lacquer
• Fungal nail infection is an infection of the nails by a
fungus and is known as Onychomycosis.
• The body normally hosts a variety of bacteria and fungi.
• Some of these are useful to the body. Others may
multiply quickly and form infections.
• Fungi can live on the dead tissues of the hair, nails, and
outer skin layers.
• Ciclopiroxtopical solution, 8%, contains a synthetic
antifungal agent, ciclopirox.
• It is intended for topical use on fingernails and toenails
and immediately adjacent skin.
28. Recent advances:
•Rehydrating Nail Hardener:
(Miracle Nail) For weak, thin, peeling, and splitting nails.
•Free Nail Strengthener:
Contains calcium and coffee extract to help strengthen and
protect nautral nails from oxidants; used for weak, thin, splitting
or peeling nails, this product is Toluene, Formaldehyde, and
Dibutyl Phthalate free.
•Nail Rebuilder:
(Anti-Aging Nail Rebuilder) For dry, cracked, yellowing and
splitting nails
•Almond Cuticle Oil with Ginseng Extract:
Moisturizes and softens cuticles while nourishing and protecting
them.
29. Recent advances (Continuation)
Mood changing nail lacquer:
•This type of nail lacquer changes its shade based on the
mood of the woman.
•When her mood is normal it remains in light shade.
•When she feels anxious the shade darkens.