Acute leukemias are clonal malignant disorders characterized by the accumulation of immature blast cells in the bone marrow, which replaces normal marrow tissue. This results in bone marrow failure and peripheral blood cytopenias. Acute leukemias are classified as either acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML) based on the affected cell lineage. Treatment involves intensive chemotherapy aimed at inducing remission followed by consolidation therapy to eradicate residual leukemia cells. Supportive care is also important to manage complications such as infection during treatment. Long term side effects can include second malignancies, organ dysfunction, and infertility. Prognosis depends on factors like age, white blood cell count, and response to initial

1. Acute leukemias Dr. Sabir M. Amin

11. Severe gum swelling at presentation in AML M5

13. Blood film of patient with ALL

14. Blood film of patient with AML

25. Pseudomonas infection of skin and nail bed in patient having treatment for AML