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Medical Clearance of
the Psychiatric Patient
A CME presentation by Gareth Wahl
What will we cover
Evidence for and against “medically clear”
An interesting case
Where to from here?
What is medically clear?
An ambiguous term
No medical issues (18yo with depression)
Concomitant medical issues with psychiatric
issues dominating (34yo poorly controlled diabetic
with depression)
Recently medically unwell but now suitable for
management in a psychiatric facility (18yo post
paracetamol OD now completed NAC)
What is medically clear?
The patient as currently assessed is medically
suitable for management in a psychiatric facility
Less ability to manage complicated illness
Some but less access to comprehensive medical
care

Not a guarantee that there is no medical illness
Not a guarantee that there is no risk of a
subsequent medical illness
How do we declare a
patient medically clear
Don’t forget the basic stuff
History including a basic psychiatric history
Examination including a basic mental state exam
Observations

Investigation if indicated
Investigation
Every test in the PathWest armamentarium?
Consider low/higher risk patient groups:
Low: Young (18-55), no medical complaints, no
new psychiatric or physical complaints, no
evidence of drug/alcohol abuse
Higher: Not low.
Specifically: atypical features on
history, examination abnormalities, substance
misuse
Low risk patients
Often need no further investigation other than
thorough history, examination, observations

Is there good evidence for “routine bloods”?
There are multiple studies suggesting this is
unnecessary
Janiak B, Atteberry S. Medical Clearance of the Psychiatric Patient in the
Emergency Department. J Emerg Med 2012, 43(5): 866-870
Olshaker et al. Medical Clearance and Screening of Psychiatric Patients in
the Emergency Department. Acad Emerg Med 1997, 4(2): 124-128
Korn et al. Medical Clearance of Psychiatric Patients without medical
complaints in the Emergency Department. J Emerg Med 2000, 18(2): 173176
Higher risk patients
FBC, UE, urine seem to be the very minimum
Consider others:
LFT
Drug levels
CK/CRP/CXR
CT Head/LP/EEG
Inpatient consultation
An interesting case
25yo female BIBA with altered mental state at
9am Monday morning
Known to be zolpidem dependent, previous
psychiatric admissions with depression
Last seen by mum on Saturday, seemed usual
self
Sunday seemed to be sleeping most of the day
Today had bizarre behaviour – defecated on floor
of bathroom, repeating “mum, mum, mum, mum”
Mum called SJA who bring patient here
HR 100, BP 130/80, SpO2 99, T 36.5
Pupils 8mm, no other neurology
Watching people move around but mute/refusing
to talk

What now?
Midazolam 2.5mg
HR lowered, pupils stayed same

“Help me get off of stilnox”
10mg diazepam orally

Mum presents, and gives additional collateral history
Two previous episodes of this both managed at
Joondalup
One of these settled spontaneously after 48 hours
when mum touched her on the lips
Decision to manage as zolpidem withdrawal
On review about 3 hours later patient watching
people move around but mute again, shutting
mouth to people trying to give her diazepam as
per WC
What now?
DDx:
Functional
BZD withdrawal
Functional

Plan:
Admit obs as zolpidem/BZD withdrawal
I expect she will improve overnight with
observation
Morning after:
Similar midazolam responsive odd behaviour
CT brain
Referred to neurology

Neurology reviewed
EEG – diffuse epileptiform activity
Contents
•
•

•
•
•
•
•
•
•
•
•

•
•
•
•

Zolpidem
Doxylamine
Ibuprofen +/- codeine
Paracetamol +/- codeine
Promethazine
Diazepam
Pregabalin
Tramadol
Caffeine
Fexofenadine
Quetiapine
Phentermine
Doxepin
Propranolol
Fenofibrate
Z drugs
GABAergic sedative/hypnotics with minimal
anxiolytic effect

Similar profile to short acting BZDs
Specific adverse effects:
Complex parasomnias
Reports of hallucinations and
psychosis, potentially not related to dose rate
Interactions with other psychotropics have
precipitated hallucinations
Non-convulsive status
epilepticus
Case reports exist of non-convulsive seizures in
the context of BZD withdrawal

Case reports exist of seizures in the context of
sudden zolpidem withdrawal
Where to from here?
Documenting medical clearance and what we
specifically mean is important

Each institution can potentially have different
requirements
For example:
Bankstown Hospital ED
PHYSICAL HEALTH REVIEW FOR MENTAL HEALTH PATIENTS
Brief description of presenting problem:
Physiological Observations:
Heart rate BP Temp Resp. rate O2Sats
Any acute physical health problems (including ingestion or drug sideeffects) ?
Is the patient excessively drowsy or confused?(distinguish confusion
from psychosis)
Can you find any evidence of physical cause for the acute
presentation?
Are there any issues that the psychiatry team should follow-up?
Any questions?

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Medical clearance of the psychiatric patient

  • 1. Medical Clearance of the Psychiatric Patient A CME presentation by Gareth Wahl
  • 2. What will we cover Evidence for and against “medically clear” An interesting case Where to from here?
  • 3. What is medically clear? An ambiguous term No medical issues (18yo with depression) Concomitant medical issues with psychiatric issues dominating (34yo poorly controlled diabetic with depression) Recently medically unwell but now suitable for management in a psychiatric facility (18yo post paracetamol OD now completed NAC)
  • 4. What is medically clear? The patient as currently assessed is medically suitable for management in a psychiatric facility Less ability to manage complicated illness Some but less access to comprehensive medical care Not a guarantee that there is no medical illness Not a guarantee that there is no risk of a subsequent medical illness
  • 5. How do we declare a patient medically clear Don’t forget the basic stuff History including a basic psychiatric history Examination including a basic mental state exam Observations Investigation if indicated
  • 6. Investigation Every test in the PathWest armamentarium? Consider low/higher risk patient groups: Low: Young (18-55), no medical complaints, no new psychiatric or physical complaints, no evidence of drug/alcohol abuse Higher: Not low. Specifically: atypical features on history, examination abnormalities, substance misuse
  • 7. Low risk patients Often need no further investigation other than thorough history, examination, observations Is there good evidence for “routine bloods”? There are multiple studies suggesting this is unnecessary Janiak B, Atteberry S. Medical Clearance of the Psychiatric Patient in the Emergency Department. J Emerg Med 2012, 43(5): 866-870 Olshaker et al. Medical Clearance and Screening of Psychiatric Patients in the Emergency Department. Acad Emerg Med 1997, 4(2): 124-128 Korn et al. Medical Clearance of Psychiatric Patients without medical complaints in the Emergency Department. J Emerg Med 2000, 18(2): 173176
  • 8. Higher risk patients FBC, UE, urine seem to be the very minimum Consider others: LFT Drug levels CK/CRP/CXR CT Head/LP/EEG Inpatient consultation
  • 10. 25yo female BIBA with altered mental state at 9am Monday morning Known to be zolpidem dependent, previous psychiatric admissions with depression Last seen by mum on Saturday, seemed usual self Sunday seemed to be sleeping most of the day Today had bizarre behaviour – defecated on floor of bathroom, repeating “mum, mum, mum, mum” Mum called SJA who bring patient here
  • 11. HR 100, BP 130/80, SpO2 99, T 36.5 Pupils 8mm, no other neurology Watching people move around but mute/refusing to talk What now?
  • 12. Midazolam 2.5mg HR lowered, pupils stayed same “Help me get off of stilnox” 10mg diazepam orally Mum presents, and gives additional collateral history Two previous episodes of this both managed at Joondalup One of these settled spontaneously after 48 hours when mum touched her on the lips
  • 13. Decision to manage as zolpidem withdrawal On review about 3 hours later patient watching people move around but mute again, shutting mouth to people trying to give her diazepam as per WC What now?
  • 14. DDx: Functional BZD withdrawal Functional Plan: Admit obs as zolpidem/BZD withdrawal I expect she will improve overnight with observation
  • 15. Morning after: Similar midazolam responsive odd behaviour CT brain Referred to neurology Neurology reviewed EEG – diffuse epileptiform activity
  • 16. Contents • • • • • • • • • • • • • • • Zolpidem Doxylamine Ibuprofen +/- codeine Paracetamol +/- codeine Promethazine Diazepam Pregabalin Tramadol Caffeine Fexofenadine Quetiapine Phentermine Doxepin Propranolol Fenofibrate
  • 17.
  • 18.
  • 19. Z drugs GABAergic sedative/hypnotics with minimal anxiolytic effect Similar profile to short acting BZDs Specific adverse effects: Complex parasomnias Reports of hallucinations and psychosis, potentially not related to dose rate Interactions with other psychotropics have precipitated hallucinations
  • 20. Non-convulsive status epilepticus Case reports exist of non-convulsive seizures in the context of BZD withdrawal Case reports exist of seizures in the context of sudden zolpidem withdrawal
  • 21. Where to from here? Documenting medical clearance and what we specifically mean is important Each institution can potentially have different requirements For example:
  • 22. Bankstown Hospital ED PHYSICAL HEALTH REVIEW FOR MENTAL HEALTH PATIENTS Brief description of presenting problem: Physiological Observations: Heart rate BP Temp Resp. rate O2Sats Any acute physical health problems (including ingestion or drug sideeffects) ? Is the patient excessively drowsy or confused?(distinguish confusion from psychosis) Can you find any evidence of physical cause for the acute presentation? Are there any issues that the psychiatry team should follow-up?