The document summarizes the three stages of cellular respiration - oxidative decarboxylation of pyruvate, the citric acid cycle (Krebs cycle), and the electron transport chain. It describes how pyruvate is converted to acetyl-CoA which feeds into the citric acid cycle. The citric acid cycle is a series of reactions that oxidizes acetyl-CoA completely, producing carbon dioxide and hydrogen carriers (NADH and FADH2) to be used in the final stage of oxidative phosphorylation.
Glycolysis is a series of reactions that extract energy from glucose by splitting it into two three-carbon molecules called pyruvates. This powerpoint Presentation includes all steps of glycolysis.
Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the high-energy molecules ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine ...
The citric acid cycle, also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle—is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate—derived from carbohydrates, fats, and proteins—into carbon dioxide.
Glycolysis is a series of reactions that extract energy from glucose by splitting it into two three-carbon molecules called pyruvates. This powerpoint Presentation includes all steps of glycolysis.
Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the high-energy molecules ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine ...
The citric acid cycle, also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle—is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate—derived from carbohydrates, fats, and proteins—into carbon dioxide.
The citric acid cycle is the central metabolic hub of the cell.
It is the final common pathway for the oxidation of fuel molecule such as amino acids, fatty acids, and carbohydrates.
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The citric acid cycle – also known as the TCA cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/
DERIVATION OF MODIFIED BERNOULLI EQUATION WITH VISCOUS EFFECTS AND TERMINAL V...Wasswaderrick3
In this book, we use conservation of energy techniques on a fluid element to derive the Modified Bernoulli equation of flow with viscous or friction effects. We derive the general equation of flow/ velocity and then from this we derive the Pouiselle flow equation, the transition flow equation and the turbulent flow equation. In the situations where there are no viscous effects , the equation reduces to the Bernoulli equation. From experimental results, we are able to include other terms in the Bernoulli equation. We also look at cases where pressure gradients exist. We use the Modified Bernoulli equation to derive equations of flow rate for pipes of different cross sectional areas connected together. We also extend our techniques of energy conservation to a sphere falling in a viscous medium under the effect of gravity. We demonstrate Stokes equation of terminal velocity and turbulent flow equation. We look at a way of calculating the time taken for a body to fall in a viscous medium. We also look at the general equation of terminal velocity.
Nucleophilic Addition of carbonyl compounds.pptxSSR02
Nucleophilic addition is the most important reaction of carbonyls. Not just aldehydes and ketones, but also carboxylic acid derivatives in general.
Carbonyls undergo addition reactions with a large range of nucleophiles.
Comparing the relative basicity of the nucleophile and the product is extremely helpful in determining how reversible the addition reaction is. Reactions with Grignards and hydrides are irreversible. Reactions with weak bases like halides and carboxylates generally don’t happen.
Electronic effects (inductive effects, electron donation) have a large impact on reactivity.
Large groups adjacent to the carbonyl will slow the rate of reaction.
Neutral nucleophiles can also add to carbonyls, although their additions are generally slower and more reversible. Acid catalysis is sometimes employed to increase the rate of addition.
hematic appreciation test is a psychological assessment tool used to measure an individual's appreciation and understanding of specific themes or topics. This test helps to evaluate an individual's ability to connect different ideas and concepts within a given theme, as well as their overall comprehension and interpretation skills. The results of the test can provide valuable insights into an individual's cognitive abilities, creativity, and critical thinking skills
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
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The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptxMAGOTI ERNEST
Although Artemia has been known to man for centuries, its use as a food for the culture of larval organisms apparently began only in the 1930s, when several investigators found that it made an excellent food for newly hatched fish larvae (Litvinenko et al., 2023). As aquaculture developed in the 1960s and ‘70s, the use of Artemia also became more widespread, due both to its convenience and to its nutritional value for larval organisms (Arenas-Pardo et al., 2024). The fact that Artemia dormant cysts can be stored for long periods in cans, and then used as an off-the-shelf food requiring only 24 h of incubation makes them the most convenient, least labor-intensive, live food available for aquaculture (Sorgeloos & Roubach, 2021). The nutritional value of Artemia, especially for marine organisms, is not constant, but varies both geographically and temporally. During the last decade, however, both the causes of Artemia nutritional variability and methods to improve poorquality Artemia have been identified (Loufi et al., 2024).
Brine shrimp (Artemia spp.) are used in marine aquaculture worldwide. Annually, more than 2,000 metric tons of dry cysts are used for cultivation of fish, crustacean, and shellfish larva. Brine shrimp are important to aquaculture because newly hatched brine shrimp nauplii (larvae) provide a food source for many fish fry (Mozanzadeh et al., 2021). Culture and harvesting of brine shrimp eggs represents another aspect of the aquaculture industry. Nauplii and metanauplii of Artemia, commonly known as brine shrimp, play a crucial role in aquaculture due to their nutritional value and suitability as live feed for many aquatic species, particularly in larval stages (Sorgeloos & Roubach, 2021).
ESR spectroscopy in liquid food and beverages.pptxPRIYANKA PATEL
With increasing population, people need to rely on packaged food stuffs. Packaging of food materials requires the preservation of food. There are various methods for the treatment of food to preserve them and irradiation treatment of food is one of them. It is the most common and the most harmless method for the food preservation as it does not alter the necessary micronutrients of food materials. Although irradiated food doesn’t cause any harm to the human health but still the quality assessment of food is required to provide consumers with necessary information about the food. ESR spectroscopy is the most sophisticated way to investigate the quality of the food and the free radicals induced during the processing of the food. ESR spin trapping technique is useful for the detection of highly unstable radicals in the food. The antioxidant capability of liquid food and beverages in mainly performed by spin trapping technique.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
ANAMOLOUS SECONDARY GROWTH IN DICOT ROOTS.pptxRASHMI M G
Abnormal or anomalous secondary growth in plants. It defines secondary growth as an increase in plant girth due to vascular cambium or cork cambium. Anomalous secondary growth does not follow the normal pattern of a single vascular cambium producing xylem internally and phloem externally.
2. CELLULAR RESPIRATION
• Under aerobic conditions, the cells obtain
energy from ATP, produced as a result of
breakdown of glucose.
• The aerobic organisms oxidize their organic
fuels completely to CO₂ and H₂O.
• In such conditions, the pyruvate, instead of
being reduced to lactate, ethanol and CO ₂,
gets completely oxidized in to CO₂ and H₂O.
• This is termed as Cellular respiration.
3. Thus Cellular respiration can be defined as:
“A sequence of molecular processes involved in
O₂ consumption and CO₂ formation by the
cells.”
4. 3 STAGES OF CELLULAR RESPIRATION
STAGE 1:
“Oxidative decarboxylation of Pyruvate to Acetyl
CoA and CO₂.”
This conversion is catalyzed by a highly organized
multienzyme “pyruvate dehydrogenase complex.”
In the overall reaction, the carbooxylic group of
pyruvate is lost as CO₂, while the remaining 2
carbons form the acetyl moeity of acetyl-CoA.
The reaction is highly Exergonic and is essentially
irreversible, in vivo.
6. • STAGE 2:
“Citric acid Cycle or Acetyl CoA catabolism”
In this stage, the acetyl group so obtained is fed
into citric acid cycle/Kreb’s Cycle which then
degrades it to yield energy rich hydrogen atoms and
to release CO₂; the final product of organic fuels.
It is the final common pathway for oxidation of fuel
molecules.
This cycle also provides intermediates for
biosynthesis.
7. • STAGE 3:
“Electron transport chain and oxidative
phosphorylation”
In this final stage of respiration, the hydrogen
atoms are separated into protons (H⁺) and energy
rich electrons.
The electrons are transferred via chain of electron-
carrying molecules, the respiratory chain, to
molecular oxygen, which is reduced by electrons to
form water.
8. PYRUVATE OXIDATION
• The oxidative decarboxylation of pyruvate to form
Acetyl CoA Is the link between glycolysis and kreb’s
cycle.
• It occurs in mitochondrial matrix.
• Here pyruvate from Glycolysis is dehydrogenated to
form Acetyl CoA and CO₂ by the enzyme pyruvate
dehydrogenase complex.
• The reaction is irreversible and can be represented
as follows:
9. COO ‾ S CoA
C O + CoA SH + NAD⁺ C O + CO₂ + NADH
CH₃ CH₃
Pyruvate
dehydrogenase
complex
Mg²⁺
Pyruvate Acetyl CoACoenzyme A
10. This conversion is catalyzed by a highly organized
multienzyme “pyruvate dehydrogenase complex.”
In the overall reaction, the carbooxylic group of
pyruvate is lost as CO₂, while the remaining 2
carbons form the acetyl moeity of acetyl-CoA.
The reaction is highly Exergonic and is essentially
irreversible, in vivo.
11. KREB’S CYCLE
• Also known as Citric acid cycle was discovered by
H.A.Kreb, German born British Biochemist.
• This cycle occurs in mitochondrial matrix in
eukaryotes and in cytosol in prokaryotes.
• The net result for this cycle is that for each acetyl
group entering the cycle as Acetyl CoA, 2
molecules of CO₂ are produced.
14. STEP1: Condensation OF Acetyl-CoA
with Oxaloacetate
• The cycle begins with the condensation of a 4
carbon unit, the oxaloacetate, and the acetyl group
of the Acetyl CoA, which is a 2 carbon unit.
• Oxaloacetate reacts with Acetyl-CoA and H₂O to
yield citrate and CoA.
• This reaction is an aldol condensation reaction and
is followed by hydrolysis.itis catalyzed by the
enzyme: “ citrate synthetase”.
16. STEP 2: ISOMERIZATION OF Citrate
INTO Iso-citrate
• In this reaction, water is first removed and then
added back, moves the hydroxyl group from one
carbon atom to its neighbor.
• The enzyme catalyzing this reaction is aconitase.
CITRATE
Aconitase
-H₂O
Cis-ACONITATE
+H₂O
ISOCITRATE
Aconitase
-H₂O
+H₂O
17. STEP 3: Oxidative Decarboxylation of
Isocitrate
• Isocitrate is oxidized and decarboxylated into
α-ketogluterate .
• This reaction is catalyzed by the enzyme “isocitrate
dehydrogenase.”
ISOCITRATE
OXALO-
SUCCINATE
(enzyme
bound)
α-
KETOGLUTERATE
NAD⁺ NADH+H⁺
H⁺ CO₂
Isocitrate
dehydogenase
Isocitrate
dehydogenase
18. STEP 4: Oxidative decarboxylation of
α-ketogluterate
• This second oxidative decarboxylation results in
formation of “Succinyl CoA” from α-ketogluterate.
• “α-ketogluterate dehydrogenase” catalyzes this
oxidative step and produces NADH, CO₂ and a high-
energy thioester bond to coenzyme-A (CoA).
20. STEP 5: Conversion of Succinyl-CoA
into Succinate
• The cleavage of the thioester bond of Succinyl-CoA
is coupled to the phosphorylation of a purine
nucleoside diphosphate, usually GDP (substtrate
level phosphorylation).
• It is catalyzed by “succinyl CoA synthetase/ succinyl
thiokinase”.
• This is the only step in the Kreb’s Cycle that directly
yields a compound with high phosphoryk transfer
potential through a substrate level phosphorylation
22. STEP 6: Dehydrogenation of Succinate
to form Fumerate
• In this third oxidation step, FAD removes 2
hydrogen atoms from succinate.
• This reaction is catalyzed by the enzyme “succinate
dehydrogenase.”
• This reaction is the only dehydrogenation in the
citric acid cycle in which NAD⁺ doesn’t participate.
Rather, hydrogen is directly transferred from the
substrate to falvoprotein enzyme (succinate
dehydrogenase).
24. STEP 7: Hydration of Fumerate to
Malate
• Fumerate is hydrated to form L-malate in the
presence of “fumerate hydratase”.
• It involves hydration i.e. addition of water to
fumerate which places a hydroxyl group next to the
carbonyl carbon.
26. STEP 8: Dehydrogenation of Malate to
Oxaloacetate
• This is the 4th oxidation-reduction reaction in the
citric acid cycle where L-malate is dehydrogenated
to oxaloacetate.
• This reaction takes place in the presence of “l L-
malatae dehydrogenase”.
• The NAD⁺ which remains linked to the enzyme
molecule acts as the hydrogen acceptor and gets
reduced to NADH and H⁺
• This reaction is a reversible reaction.
27. • Although the equilibrium of this reaction favours
formation of malate again, but the reaction
proceeds forward since the oxaloacetate and the
NADH so formed are removed rapidly and
continuously in the further reactions.
• The generated Oxaloacetate allows repetition of the
cycle and NADH precipitates in oxidative
phosphorylation
• This reaction completes the cycle.
28. COO‾
HO C H
H C H
COO ‾
L-Malate
+ NAD⁺
COO ‾
C O
CH₂
COO ‾
++ NADH H⁺
OXALOACETATE
L-malate
dehydrogenase