This document describes the simulation and design of a coaxial fed tri-band microstrip patch antenna for wireless communication applications. The antenna is designed to operate in three bands: 2.28-2.35 GHz, 4.05-4.11 GHz, and 5.8-5.9 GHz. Rectangular slots are introduced on the patch to achieve the triple band performance. The dimensions of the slots and ground plane as well as the feed position are optimized using HFSS simulator. Simulation results show return losses less than -25 dB across the three bands and VSWR less than 2, indicating good impedance matching between the feed line and patch. Radiation patterns and efficiencies over 95% are obtained at the center frequencies