Oral medicine deals with diagnosis, treatment and prevention of oral mucosal diseases, local oral diseases, and oral manifestations of systemic diseases. It also involves dental management of medically compromised patients. Oral radiology uses x-rays to produce images of oral tissues. Oral diagnosis identifies oral diseases based on their symptoms and signs. These specialties classify oral lesions based on factors like etiology, pathological process, clinical appearance, and origin to facilitate diagnosis and treatment.
In this lecture I explain in step-by-step fashion the basics of Endodontic Diagnosis: Pulp Vitality Tests. a photo guide is attached to the guide to aid in better understanding of the topic
A absolutely minimalist way to describe each and every diagnostic aid in the beautiful stream of endodontics.
one has to understand the topic by going through the bible, "Grossman 13th Edition" along with the slides I've created.
Hope this helps.
by Dr. Ishaan Adhaulia
In this lecture I explain in step-by-step fashion the basics of Endodontic Diagnosis: Pulp Vitality Tests. a photo guide is attached to the guide to aid in better understanding of the topic
A absolutely minimalist way to describe each and every diagnostic aid in the beautiful stream of endodontics.
one has to understand the topic by going through the bible, "Grossman 13th Edition" along with the slides I've created.
Hope this helps.
by Dr. Ishaan Adhaulia
A well pictured presentation on Endodontic Instrumentation for UG students. Best for getting a good grip on the topic as a whole. Meant to supplement not substitute standard texts.
A well pictured presentation on Endodontic Instrumentation for UG students. Best for getting a good grip on the topic as a whole. Meant to supplement not substitute standard texts.
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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Introduction oral medicine-primary and secondary lesions
1.
2. Oral Medicine & Radiology
Oral
Diagnosis
Oral
Medicine
Oral
Radiology
3. Definitions
Oral Diagnosis is defined as an art and science of
identifying an oral disease from its symptoms and signs.
Oral Oral Medicine Radiology is is defined defined as as that a science branch composed of dentistry
of
which technical deals and with:
interpretative procedures that
1. Diagnosis, treatment and prevention of:
interdependently result in useful diagnostic data.
a. Oral mucosal diseases
b. Local oral diseases
c. Oral manifestations of systemic diseases
Oral Radiography is defined as an art and science of
producing photographic image of oral tissues through
use of x-radiation.
2. Dental management of physiologically compromised
patients.
4. Reading Material
Lecture notes
Burket’s Oral Medicine
by Malcolm Lynch, 8th / 9th Edition
Oral Radiology: Principles & Interpretation
by Goaz & White, 2nd / 3rd Edition
Differential Diagnosis of Oral Lesions
by Goaz & Wood, 2nd / 3rd Edition
5. Oral Medicine is defined as that branch of
dentistry which deals with:
1. Diagnosis, treatment and prevention of:
a. Oral mucosal diseases
b. Local oral diseases
c. Oral manifestations of systemic
diseases
2. Dental management of physiologically
compromised patients.
6. Oral Medicine
Oral mucosal
diseases
Local oral
diseases
• Oral manifestations of systemic diseases
• Dental management of physiologically
compromised patients.
7. CLASSIFICATION OF ORAL DISEASES
Some ways of classifying oral diseases :
~ Based on etiology
e.g. viral, traumatic
~ Based on the pathological process involved
e.g. inflammatory, neoplastic
~ Based on symptoms
e.g. recurrent, painful conditions, tumorous
conditions
~ Based on clinical appearance of lesions
e.g. ulcerative, vesicular, erosive
~ Based on origin
e.g. developmental, acquired
8. “A lesion is a localized area of disease or
injury in any organ or tissue of the body”
ORAL SOFT TISSUE LESIONS
WHITE
ULCER
EXOPHYTIC
YELLOW DRAINING
and PITS
BROWNISH,
BLUISH
or BLACK
RED
Keratotic
Necrotic
Solitary Generalized Tongue
10. Another way of classifying oral lesions :
PRIMARY
LESION
SECONDARY
LESION
Macule, Plaques, Papule, Patch
Nodule, Tumor
Vesicle, Bulla, Pustule
Petechia, Ecchymosis
11. Macule: Sharply circumscribed discoloration (flat) up to 1
cm in diameter
Patch: Sharply circumscribed discoloration (flat) more
than 1 cm in diameter
12. Papule: Well circumscribed, solid, flat-topped raised lesion
up to 1 cm in diameter
Plaque: Well circumscribed solid raised lesion more
than 1 cm in diameter
13. Nodule: Well circumscribed solid, rounded projection up
to 1 cm in diameter
Tumor: Well circumscribed solid, rounded projection
more than 1 cm in diameter
14. Vesicle: Sharply circumscribed serous fluid-filled elevation
up to 1 cm in diameter
Bulla: Sharply circumscribed serous fluid-filled elevation
more than 1 cm in diameter
15. Vesicle: Sharply circumscribed serous fluid-filled elevation
up to 1 cm in diameter
Bulla: Sharply circumscribed serous fluid-filled elevation
more than 1 cm in diameter
16. Vesicle: Sharply circumscribed serous fluid-filled elevation
up to 1 cm in diameter
Bulla: Sharply circumscribed serous fluid-filled elevation
more than 1 cm in diameter
18. Petechiae: Sharply circumscribed deposit of blood or
blood pigments up to 1 cm in diameter
Ecchymosis: Sharply circumscribed deposit of blood or
blood pigments more than 1 cm in diameter
19. Petechiae: Sharply circumscribed deposit of blood or
blood pigments up to 1 cm in diameter
Ecchymosis: Sharply circumscribed deposit of blood or
blood pigments more than 1 cm in diameter
20. Another way of classifying oral lesions :
PRIMARY
LESION
SECONDARY
LESION
Erosion, Ulcer, Scar
Infiltration
21. Erosion: Loss of superficial layers of epithelium
Ulcer: Break in the continuity of the epithelium (deeper
than an erosion)
22. Scar: Deposit of highly fibrous tissue subsequent to ulcer or
injury
Infiltration: Extension of the primary lesion into the
deeper tissue causing fixity or induration
23. “Colour Atlas of Oral Diseases”
George Laskaris
2nd Edition, 1994
24. DESCRIPTION OF A DISEASE PROCESS
Definition
Etiology & Pathogenesis
Epidemiology
Clinical Features : age, sex, site, symptoms & signs
Radiographic Features
Histological Features
Investigations, Diagnosis & Differential Diagnosis
Treatment & Prognosis