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INTRA-OCULAR LENS
VISHNU NARAYANAN
What is intraocular lens?
• An artificial lens implanted in the eyes
• Replaces the crystalline lens
• To correct the optical power of the eyes
following:-
Lens being
clouded by
cataract
Refractive surgery
Primary vs secondary implantation
• Primary implantation – use of IOLs during
surgery for cataract
• Secondary implantation – implantation of IOL
to correct aphakia in a previosly operated eye
Parts of an IOL
• OPTIC
Part of the lens that focuses
light on the retina.
• HAPTIC
Small filaments connected to
the optic that hold the lens in
place in the eye
HAPTEN
OPTIC
HISTORY OF IOL
• K
THE FIRST IOL!!
• PMMA made lens – 45 year
old female after performing
extracapsular cataract
extraction
• Disc shaped bi-convex design
• Site- posterior chamber
• First generation IOL
EVOLUTION OF IOLs
1. First generation IOLs
• Ridley lenses
• Disadvantages – posterior dislocation
poor surgical technique
2. Second generation IOLs
• Rigid and semi-rigid anterior chamber IOLs
• Advantages – reduce posterior dislocation
• Disadvantage – corneal decompensation
UGH syndrome
3. Third generation IOLs
• Iris supported lens
• Advantages- less corneal decompensation
• Disadvantages – iris chaffing
pupillary distortion
c/c inflammation
cystoid macular edema
4. Fourth generation IOLs
• Modern anterior chamber lens
• Flexible loops and multiple point fixation
• Advantages – more stable, better design, less
complications
• Disadvantages – anterior chamber is not the
physiological site for IOL
5. Fifth generation IOLs
• PMMA lenses
• Foldable and small incision lenses
MATERIALS USED FOR INTRAOCULAR
LENSES
Optic materials
1.Non-foldable-rigid IOL
• Polymethyl
methacrylate(PMMA)
2.Foldable IOL
• Silicone
• Hydrophobic acrylic
• Hydrophilic acrylic
3.Rollable/Ultra-thin IOL
• hydrogel
Haptic materials
• Polypropylene
• PMMA
• Acrylic
POSITIONING OF IOL
1. Posterior chamber
implantation
• Ciliary sulcus fixation
• In the bag fixation
• Scleral fixation
Eg:- modified C loop type
IOL
Ciliary sulcus fixation
In-the-bag fixation
Scleral IOL
2. Anterior chamber
implantation
• angle supported IOLs
• Kelman multiflex type
IOL
3. Iris- fixated lens
• Fixed on the iris with
claws,loops or sutures
• Eg- Singh and Worst’s
iris claw lens
Different types of haptic angulation
relative to the plane of optic:-
For posterior chamber lens:-
• 100 anterior angulation to keep the optic
part away from the pupil.
For anterior chamber lens:-
• Posteriorly angulated lens to vault the
intraocular lens away from the pupil
FOCUSSING ABILITY OF IOLs
1. Unifocal intraocular lens
• Lens with unifocal power
• Can have problem with near vision
2.Multifocal IOLs
• Simultaneous vision
lenses
• Based on either refractive
or diffractive optics
• Psuedoaccomodation lens
3.Accomodative IOLs
• Exhibit anterior movement of optic
to improve near vision
Special function IOLs
TORIC IOLs
• Correct any associated
astigmatism
ASPHERIC IOLs
• Reduce spherical
aberration
ANIRIDIA IOLs
• Cover the defects of aniridia or
partial iris loss as in trauma
• Has a black diaphragm over the
optic
PIGGYBACK IOLs
• An IOL piggybacking onto an
existing IOL or simultaneous
implantation of 2 IOLs
BLUE LIGHT FILTERING IOLs
• Lenses are yellow colored to screen out UV
Light and blue spectrum
• Reduced risk of age related macular
degeneration
PHOTOCHROMATIC IOLs
• UV absorbing photo chromes
IMPLANTABLE MINIATURE
TELESCOPE
• Miniature implantable Galilean
telescope
• Implanted in posterior chamber
• Contains number of micro lenses
in the optic which gives a
magnification of about 3 at the
central visual field
• Used to treat macular
degeneration
TELESCOPIC IOLs
• New generation miniature
telescopes which uses 2 mirrors
instead of lens to provide
magnification with minimum
loss of peripheral vision
Phakic IOLs
• IOLs used to correct myopia with the eye’s
natural lens being untouched
• Implantable contact lenses
1. Angle supported lens
2. Iris – fixated lens
3. Sulcus supported lens
BIOMETRY
THEORETICAL FORMULAE
• Binkhorst formula
• Colenbrander’s formula
• Gull strand’s formula
• Hoffer’s formula
EMPERICAL FORMULAE
• Modified Sanders-Retzlaff-Kraff formula
• SRK II
• SRK III
• SRK T
• Haigis formula
Binkhorst formula
• E= [N/(L-C)] – NK/(N-KC)]
E
• Emmetropic IOL power
L
• Axial length of the eye
K
• Corneal dioptric power
C
N
• Psuedophakic length of anterior chamber
• Refractive index of aqueous and vitreous humor
Modified Sanders-Retzlaff-
Kraff formula
• Based on the statistical correlation
between calculated and observed
refractive error after ocular
implantation.
Modified SRK Formula
• E=A - 2.5L - 0.9K
• Parameters used in the formula are
estimated by
• A-scan ultrasonographic sonometry and
keratometry
• Instrument - biometer
E=A - 2.5L - 0.9K
• Power ( I )required to produce Required post
operative refraction ( R ) ,
I = E – cr R
• cr – empirical constant
cr = 1 if E < 14
cr = 1.25 if E > 14
Complications of IOL implantation
• Mechanical damage to the IOL
• Dislocation
• Bullous keratopathy
• Posterior capsule rupture
• Anterior capsule opacification
• Posterior capsule opacification
• Calcium deposits within the optic of hydrophilic
intraocular lens
• Adherence
• UGH syndrome
• Sunset syndrome
Sunset syndrome
“Lens of the future”-liquid injectable
IOLs
• A new IOL concept that combines an acrylic
IOL with a liquid, injectable IOL may someday
allow patients to retain accommodation.
• Following IOL implantation, liquid IOL is injected
and capsular bag is inflated fully and IOL kept in
place
• Mechanism- forward movement and thickening
of lens
Intra ocular lens

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Intra ocular lens

  • 2. What is intraocular lens? • An artificial lens implanted in the eyes • Replaces the crystalline lens • To correct the optical power of the eyes following:- Lens being clouded by cataract Refractive surgery
  • 3. Primary vs secondary implantation • Primary implantation – use of IOLs during surgery for cataract • Secondary implantation – implantation of IOL to correct aphakia in a previosly operated eye
  • 4. Parts of an IOL • OPTIC Part of the lens that focuses light on the retina. • HAPTIC Small filaments connected to the optic that hold the lens in place in the eye HAPTEN OPTIC
  • 6. THE FIRST IOL!! • PMMA made lens – 45 year old female after performing extracapsular cataract extraction • Disc shaped bi-convex design • Site- posterior chamber • First generation IOL
  • 7. EVOLUTION OF IOLs 1. First generation IOLs • Ridley lenses • Disadvantages – posterior dislocation poor surgical technique 2. Second generation IOLs • Rigid and semi-rigid anterior chamber IOLs • Advantages – reduce posterior dislocation • Disadvantage – corneal decompensation UGH syndrome
  • 8. 3. Third generation IOLs • Iris supported lens • Advantages- less corneal decompensation • Disadvantages – iris chaffing pupillary distortion c/c inflammation cystoid macular edema
  • 9. 4. Fourth generation IOLs • Modern anterior chamber lens • Flexible loops and multiple point fixation • Advantages – more stable, better design, less complications • Disadvantages – anterior chamber is not the physiological site for IOL
  • 10. 5. Fifth generation IOLs • PMMA lenses • Foldable and small incision lenses
  • 11. MATERIALS USED FOR INTRAOCULAR LENSES Optic materials 1.Non-foldable-rigid IOL • Polymethyl methacrylate(PMMA) 2.Foldable IOL • Silicone • Hydrophobic acrylic • Hydrophilic acrylic 3.Rollable/Ultra-thin IOL • hydrogel Haptic materials • Polypropylene • PMMA • Acrylic
  • 12. POSITIONING OF IOL 1. Posterior chamber implantation • Ciliary sulcus fixation • In the bag fixation • Scleral fixation Eg:- modified C loop type IOL
  • 16. 2. Anterior chamber implantation • angle supported IOLs • Kelman multiflex type IOL
  • 17. 3. Iris- fixated lens • Fixed on the iris with claws,loops or sutures • Eg- Singh and Worst’s iris claw lens
  • 18. Different types of haptic angulation relative to the plane of optic:- For posterior chamber lens:- • 100 anterior angulation to keep the optic part away from the pupil. For anterior chamber lens:- • Posteriorly angulated lens to vault the intraocular lens away from the pupil
  • 19.
  • 20. FOCUSSING ABILITY OF IOLs 1. Unifocal intraocular lens • Lens with unifocal power • Can have problem with near vision
  • 21. 2.Multifocal IOLs • Simultaneous vision lenses • Based on either refractive or diffractive optics • Psuedoaccomodation lens
  • 22. 3.Accomodative IOLs • Exhibit anterior movement of optic to improve near vision
  • 23. Special function IOLs TORIC IOLs • Correct any associated astigmatism ASPHERIC IOLs • Reduce spherical aberration
  • 24. ANIRIDIA IOLs • Cover the defects of aniridia or partial iris loss as in trauma • Has a black diaphragm over the optic PIGGYBACK IOLs • An IOL piggybacking onto an existing IOL or simultaneous implantation of 2 IOLs
  • 25. BLUE LIGHT FILTERING IOLs • Lenses are yellow colored to screen out UV Light and blue spectrum • Reduced risk of age related macular degeneration PHOTOCHROMATIC IOLs • UV absorbing photo chromes
  • 26. IMPLANTABLE MINIATURE TELESCOPE • Miniature implantable Galilean telescope • Implanted in posterior chamber • Contains number of micro lenses in the optic which gives a magnification of about 3 at the central visual field • Used to treat macular degeneration
  • 27. TELESCOPIC IOLs • New generation miniature telescopes which uses 2 mirrors instead of lens to provide magnification with minimum loss of peripheral vision
  • 28. Phakic IOLs • IOLs used to correct myopia with the eye’s natural lens being untouched • Implantable contact lenses 1. Angle supported lens 2. Iris – fixated lens 3. Sulcus supported lens
  • 29. BIOMETRY THEORETICAL FORMULAE • Binkhorst formula • Colenbrander’s formula • Gull strand’s formula • Hoffer’s formula EMPERICAL FORMULAE • Modified Sanders-Retzlaff-Kraff formula • SRK II • SRK III • SRK T • Haigis formula
  • 30. Binkhorst formula • E= [N/(L-C)] – NK/(N-KC)] E • Emmetropic IOL power L • Axial length of the eye K • Corneal dioptric power C N • Psuedophakic length of anterior chamber • Refractive index of aqueous and vitreous humor
  • 31. Modified Sanders-Retzlaff- Kraff formula • Based on the statistical correlation between calculated and observed refractive error after ocular implantation.
  • 32. Modified SRK Formula • E=A - 2.5L - 0.9K • Parameters used in the formula are estimated by • A-scan ultrasonographic sonometry and keratometry • Instrument - biometer
  • 33. E=A - 2.5L - 0.9K
  • 34. • Power ( I )required to produce Required post operative refraction ( R ) , I = E – cr R • cr – empirical constant cr = 1 if E < 14 cr = 1.25 if E > 14
  • 35. Complications of IOL implantation • Mechanical damage to the IOL • Dislocation • Bullous keratopathy • Posterior capsule rupture • Anterior capsule opacification • Posterior capsule opacification • Calcium deposits within the optic of hydrophilic intraocular lens • Adherence • UGH syndrome • Sunset syndrome
  • 37. “Lens of the future”-liquid injectable IOLs • A new IOL concept that combines an acrylic IOL with a liquid, injectable IOL may someday allow patients to retain accommodation. • Following IOL implantation, liquid IOL is injected and capsular bag is inflated fully and IOL kept in place • Mechanism- forward movement and thickening of lens

Editor's Notes

  1. No loss of peripheral vision