Glucocorticoids have metabolic effects such as increasing hepatic gluconeogenesis and reducing glucose utilization in cells. They play an important role in the body's adaptation to stress and have anti-inflammatory and anti-allergic effects. Long term use of glucocorticoids can have undesirable side effects including gastric ulcers, high blood pressure, and bone thinning. Aldosterone has a greater mineralocorticoid activity than cortisol and its effects include regulating sodium and potassium levels and blood pressure. Conditions like Cushing's syndrome and Addison's disease involve imbalances in cortisol and aldosterone levels in the body.