This document discusses global biodiversity patterns and loss of biodiversity. It defines biodiversity as the variety of life on Earth, including diversity within and between species and ecosystems. It notes that biodiversity is highest in tropical regions and identifies 34 global biodiversity hotspots that contain over half of the world's plant and vertebrate species on just 2.5% of land. The major threats to biodiversity are habitat loss and degradation, overexploitation, pollution, climate change, and invasive species. Deforestation, urbanization, and agriculture have destroyed much natural habitat and led to population declines and extinctions in many species. Over 38% of evaluated species are now considered threatened with extinction.