The document summarizes quinolones and fluoroquinolones. Quinolones are a family of synthetic broad-spectrum antibacterial drugs that prevent bacterial DNA from duplicating. Fluoroquinolones are derived from quinolones and have an even broader spectrum. They are classified into generations based on their spectrum, with later generations having increased gram-positive and atypical coverage. Fluoroquinolones are generally well-absorbed, penetrate tissues deeply, and have few drug interactions or side effects, making them preferred drugs. However, their overuse has led to increasing antimicrobial resistance.