This document provides an overview of the course content covered in MDCAT NUMS MCQ exams. It lists the main topics covered in biology including cell biology, biological molecules, microbiology, animalia, human physiology, bioenergetics, biotechnology, ecosystems, evolution, and diseases. It also provides the marks distribution across biology, chemistry, physics, and English subjects. The total marks for the exam are 220 or 180 depending on the version.
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Viruses are small, acellular particles that can replicate only in a host cell. They are obligatory intracellular parasites.They
consist of a nucleic acid genome enclosed in a protective protein shell or capsidBacteriophage is the virus that infect bacteria.Bacteriophages were discovered by Frederick Twort(1915)and Felix d'Herelle(1917).
There are different strategies bacterial cells use to survive. Differentiation can be occasionally one of them. Although differentiation can occur in the bacterial life cycle, it is a strategy to adapt themselves to harsh environments.
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Viruses are small, acellular particles that can replicate only in a host cell. They are obligatory intracellular parasites.They
consist of a nucleic acid genome enclosed in a protective protein shell or capsidBacteriophage is the virus that infect bacteria.Bacteriophages were discovered by Frederick Twort(1915)and Felix d'Herelle(1917).
There are different strategies bacterial cells use to survive. Differentiation can be occasionally one of them. Although differentiation can occur in the bacterial life cycle, it is a strategy to adapt themselves to harsh environments.
Classification of Bacteria microbiologyVinay Dhiman
Based on Bergey's Manual of systematic classification 2nd edition microbiology,Life sciences
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Introduction and Brief about Bacteriology, Bacterial Structure, Difference Between Gram Positive and Gram Negative Bacteria, Flagellar structure, Cell wall Structure,
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
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Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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9. b = 30% = 0.3, B = 1-0.3 = 0.7 Bb= 0.3x0.7= 0.21 x 2 = 0.42
10.
11. Part of Cell Discovery Composition Functions
Cell Wall Robert Hooke Cellulose, hemicellulose, lignin, pectin,
silica, wax, salt
Protection, covering, prevent from osmotic lysis
Cell Membrane Schwann 60-80% proteins, 20-40% lipids,
glycogen, cholestol
Tranportation, passive transport, active transport, endocytosis, phagocytosis,
pinocytosis,
Cytoplasm H2O, enzymes, cytogel, cytosol, ground,
fundamental substances
Metabolic pathway-glycolysis, cyclosis, taxis, store house of chemicals,
substrate phosphorylation
E.R Keith R Porter RER, SER, cisternae Protein synthesis, transportation, detoxification, Ca transport
Ribosome
Polysome
Palade rRNA, protein, 70S, 80S Protein synthesis by translation
GB C.Golgi Cisternae, lipid, protein, forming and
maturation face
cell secretions (secretory house), formation of granules, vesicles, blebs,
lysosomes
Lysosome D Duve lipid, protein, enzymes, Pri & Sec
lysosomes (autophagosome)
Digestion, autophagy, autolysis, digestive organ of cell
Storage Congenital Diseases, Glycogenosis, Tay Sach’s
Peroxisome D Dove lipid, protein, enzymes metabolism of peroxides, microbodies
Glyoxysome lipid, protein, enzymes metabolism of lipid, glyoxylate cycle , provide energy during seed germination,
microbodies
Vacuole lipid, protein,
Food Vacuole, contractile vacuole,
secretory vacuoles
Tonoplast, prevent from osmotic lysis, cell elongation, turidity, Ψp, K, salt, food
& starch, waste & extra water store.
Cytoskeleton Protein-actin, myosin, tropomyosin,
troponin, flagellin, tubulin
Microtubules-assembly and disassembly spindle, formation of cilia, flagella,
basal bodies and centrioles.
Microfilaments- contain contractile actin protein, at plasma membrane, cyclosis
and amoeboid movements.
Intermediate filaments- maintain cell shape, cell shape and integration of
cellular compartments.
Centriole
Centrosome
Protein, nine microtubules with triplet, Location of furrowing formation during cell division (cytokinesis), and help in
cilia formation.
Mitochondria lipid, protein, enzymes, Cristae Power house of cell, Kreb’s cycle, ETC, chemiosmosis, oxidative
phosphorylation, photorespiration, rigor mortis
Plastids; Chloroplast, Chromoplast,
Leucoplast
lipid, protein, enzymes-Rubisco Photosynthesis-light&dark reaction (Calvin cycle), ETC, chemiosmosis,
photolysis, photorespiration, photophosphorylation
Nucleus Robert Brown lipid, protein, enzymes-nuclease, ligase Controlling authority, contain nucleolus, chromosomes, transcription, central
(gene dogma)
Virus DNA RNA Enveloped Non-
Enveloped
Bacteriophage DNA Non-Enveloped
Pox virus DNA enveloped
Herpes virus DNA enveloped
Influenza viruses RNA enveloped
Mumps RNA enveloped
Measles RNA enveloped
Paramyxoviruses RNA enveloped
Polioviruses RNA Non-Enveloped
Retrovirus RNA enveloped
HIV RNA enveloped
Oncovirus RNA enveloped
Tumor Virus RNA enveloped
HAV RNA Non-Enveloped
HBV DNA enveloped
HCV RNA enveloped
HDV RNA enveloped
HEV RNA Non-Enveloped
Archaeobacteria Eubacteria
Bacteria Cyanobacteria
Do not form spores Form spores Form spore like
akinetes
Found in hot springs and hot
lakes
They are cosmopolitan In fresh water
They produce methane They produce S They produce O2
Not pathogen or parasite They may pathogen or
parasite
Autotrophs only
They do not contain
peptidoglycan
They contain
peptidoglycan
contain
peptidoglycan
Some without cell wall All contain cell wall Contain cell wall
Contain sterol in cell
membrane
Don’t contain Don’t contain
e.g. Mycoplasma e.g. cocci, bacilli, spirilla e.g. Nostoc
12. Category Microorganism Size
smallest virus parvoviruses 20 nm
largest virus poxviruses 250 nm
smallest bacteria Mycoplasma 100 — 200 nm, or 0.1-0.2 µm
longest bacteria Spirochetes 500 µm
largest bacteria Epulopiscium fishelsoni 600 µm (L) 80 µm (W)
most common bacteria Escherichia coli (E.coli) 2.0 - 6.0 µm (L) 1.1 - 1.5 µm (W)
The smallest virus is parvoviruses which is 20 nm (produce diseases in gut and lymph).
The largest and the most complex virus is poxviruses which is 250 nm.
The longest bacteria is Spirochetes (gram-negative), which is about 500 µm long.
The smallest bacteria is Mycoplasma, which is about 0.1-0.2µm.
Categories Arrangements Division/ Planes Shape Examples
Cocci
Diplococci 1 plane pair of cocci Diplococcus
pneumoniae
Gram -v & +ve
Tetrad 2 planes square of 4 cocci Micrococcus
Sarcina 3 planes cube of 8 cocci
(2x2x2), rectangular
Clostridia
Streptococcus 1 plane long chain of cells Streptococcus
Staphylococus random planes Irregular Staphylococcus
Characteristics Gram-Positive Gram-negative
1. Gram’s Stain
2. CV complex
3. Number of major layers
4. Chemical nature of cell wall
5. Overall thickness (cell wall)
6. Outer membrane
7. Periplasmic space
8. Permeability
9. Pili
10. Examples
stained purple
retain the primary dye due to CV-1 complex
1
Peptidoglycan (50% of dry weight
Teichoic acid
Lipoteichoic acid
Lipids (1-4%)
20-80nm
No
Present in some
More permeable
Absent
Actinomycetes, Bacillus, Staphlococus,
Streptococus
stained pink
retain secondary dye
2
Peptidoglycan (10% dry weight)
of some bacterial cells
Lipopolysaccharides
Lipoproteins
Lipids (11-12%)
8-11nm
Yes
Present in all
Less permeable
Present
E. coli, Nitrobacteria, Pseudomonas,
Vibrio, Salmonella, Haemophillus
Column I Column II
Division in one plane; cocci arranged in pairs Diplococcus
Division in one plane; cocci arranged in chains Streptococcus
Division in two planes; cocci arranged in a square of four Tetrad
Division in 3 planes; cocci arranged in a rectangle Sarcina
Division in one plane: rods completely separate after division Bacillus
Division in one plane; rods arranged in chains Streptobacillus
Division in random planes; cocci arranged in a irregular cluster Staphylococcus
A comma shaped bacterium Vibrio
A thin, flexible spiral Spirochete
Phylum Examples Sexual rep Asexual rep Hyphae
Zygonycota
(Zygonycotes)
Rhizopus, (Black, bread
mold)
Pilobolus (spitting
fungus)
Zygospores Non – motile
spores
form in
sporangia
Non – septate,
multi nucleate
Ascomycota
(Ascomycetes
or sac – fungi)
Yeasts, morels,
truffles, powdery
mildews,
molds
Ascospores inside
ascus
Like asci
Conidia cut off
from
tips of
conidiophores
Septate,
Lengthy dikaryotic phase.
Basidiomycota
(Basidiomycetes
or club – fungi)
Mushrooms, rusts,
smuts,
puff, balls, bracket fungi
Basidiospores borne
on club shaped
basidia
Uncommon Septate,
Lengthy dikaryotic phase.
Deuteromycota
(Deuteromycetes/
Imperfect fungi)
Aspergillus, Penicillium,
Alternaria
Sexual phase has not
been
Observed
Conidia Varied
Organism Local Common Names Binomial Nomenclature
Onion Pakistani Urdu names are 'Piyaz', 'ganda', basal,'
vassal'
Allium cepa
Amaltas 'argvad', 'gurmala', 'golden shower', purging
cassia'
Cassia fistula
'Blue bell' dozens plants with bell shaped flowers
'Black bird crow as well as a raven Corvus corone (crow)
Corvus corax (raven)
Man Insan, banda, human, Homo sapiens
Fish 'silver fish' and cray fish (arthropod), jelly fish'
13. GLANDS/ORGAN HORMONES FUNCTIONS DISEASES
Hypothalamus ADH water reabsorption diabetes insipidus
Pancreas Insulin Metabolism of glucose diabetes mellitus
Hypothalamus Oxytocin parturition and suckling, let down milk sterility
Anterior lobe of pituitary gland STH promote protein synthesis Gigantism
Acromegaly
Dwarfism
Anterior lobe of pituitary gland TSH rapid growth and development Goiter
Cretinism
Thyroid Excess Thyroxin BMR Graves' disease
cardiac failure
Iodine Deficiency Growth, metabolism Goiter
Lack of Thyroxin
hypothyroidism
growth and development Cretinism
hypothyroidism Weight, growth Myxoedema
calcitonin Lower Ca+2 in blood Massive Bone
Parathyroid gland Parthormone
Under-activity
Increases Ca+2
Take Ca+2 from bone
muscular tetany, osteoporosis
Parthormone
Over-activity
Increases Ca+2 in blood Demineralization
Kidney stone
Anterior lobe of pituitary gland ACTH stress e.g. cold, heat, pain, fright, infections disturbance of normal adrenal
functions
Anterior lobe of pituitary gland FSH in Females follicle development and secretion of oestrogens Sterility, infertility
Anterior lobe of pituitary gland FSH in Male Development of the germinal epithelium of testis
and sperm production.
Sterility, infertility
Anterior lobe of pituitary gland Prolactin Stimulates milk production
Anterior lobe of pituitary gland LH / FSH stimulate oestrogen secretion,
Anterior lobe of pituitary gland ICSH in male stimulates the interstitial cells of testis to
secrete testosterone
Anterior lobe of pituitary gland MSH in pregnancy stimulates melanocytes in skin to
produce melanin, which darkens the skin
Addison's disease, Moon face
disease
Adrenal Glands ACTH, Cortical Hormones Stress, metabolism, Addison's Disease
Pituitary Gland, Adrenal Glands ACTH, excess steroid cortical hormones metabolism Cushing's disease
Anaerobic Respiration Lactic Acid Physilogical, Muscular activity muscle fatigue
Parathyroid hypocalcaemia twitches and convulsion Tetany
Clostridium tetani Toxic Effect Muscles stiffness of jaws and neck Tetanus
Symbol Nature
Ψw Water potential
Ψs osmotic potential
Ψp Pressure potential
A Angstrom
A anisotropic
AA Amino Acids
ABA Abscisic Acid
ACTH Adrenocorticotrophic Hormone
AD Alzheimer's disease
ADH Antidiuretic Hormone or Vasopressin
ADP Adenosine Diphosphate
A anisotropic
ANS Autonomic Nervous System
ATP Adenosine Triphosphate
BMR Basal metabolic rate
CRF Corticotrophin Releasing Factor
CNS Central Nervous System
CSF Cerebrospinal Fluid
D Dextro (right), clockwise
d Deoxyribose
DCT distal convoluted tubule
DNA Deoxyribonucleic Acid
EEG Electroencephalography
ER Endoplasmic Reticulum
FA Fatty Acids
FSH Follicle Stimulating Hormone
GH Gonadotrophic Hormones
GDNF Glial cell-line Derived Neurotrophic Factor
H hele
HRF Hypothalamic Releasing Factor
HSP Heat Shock Proteins
I isotropic
ICSH Interstitial Cell Stimulating Hormone
IRM Innate Releasing Mechanism
L Levo (left), anti-clockwise
L- dopa Dopamine
LH Luteinising Hormone
LTH Luteotrophic Hormone,
M Middle
MSH Melanophore Stimulating Hormone
OT Oxytocin
PCF Pericardial Fluid
PCT proximal convoluted tubule
PD Parkinson’s Disease
PIH Prolactin Inhibiting Factor
PL Prolactin
PNS Parasympathetic Nervous System
RER Rough Endoplasmic Reticulum
RNA Ribonucleic Acid
S Svedberg
SER Smooth Endoplasmic Reticulum
SNF Synovial Fluid
SNS Somatic Nervous System
SR sarcoplasmic reticulum
SRF Somatotrophin Releasing Factor
STH Somatotrophin Hormone
T T-lymphocytes
T-phage Bacteriophage
T-tubule Transversal Tubules
TG Triglyceride
TMO trimethylamine oxide, creatine
TMV Tobacco Mosaic Model
T.P turgor pressure
T, T3,T4 Thyroxin, tri and tetraiodo-thyonine:
TRF Thyrotrophin Releasing Factor
TSH Thyroid Stimulating Hormone
Z zwishen
Organism Scientific / Botanical Names
Onion Allium cepa
first microbe of known genome Haemophilus influenza
Digger Wasp Ammophila adriaanse
Tetanus Bacteria Clostridium tetani
Earthworm Lumbricus terrestris
Cockroach Periplaneta americana
Corn Zea mays
amaltas Cassia fistula
man Homo sapiens
potato Solanum tuberosum
brinjal Solanum melangena
E. coli, Gram’s +ve bacteria Escherichia coli.
M I C R O B O D I E S
Peroxisome Glyoxysome
i. The microbody which
help in metabolism of
peroxides
The microbody which help in
metabolism of lipid
i. It helps in
photorespiration
It helps in glyoxylate cycle
i. They remain functional
throughout life
They are functional only during
seed germination
i. Their enzymes are
oxidative, peroxidase,
catalase, glycolic acid
oxidase
Their enzymes are oxidative,
catalase, glycolic acid oxidase
i. They have 0.5 µm in
diameter.
They have 0.7 µm in diameter.
i. E.g. in all eukaryotes. E.g. castor bean, sunflower and
soya beans.
Individual 2N (Body Cell) N (germ cell)
Chimpanzee 48 24
Potato 48 24
Human 46 23
Frog 26 13
Onion 16 8
Garden Pea 14 7
Fruit fly (Drosophila 8 4
14. Process Step
No
ATP
use
Direct ATP
Produced
NADH FADH ETC CO2
produce
H2O Total
ATP
GLYCOLYSIS 1 ATP
GLYCOLYSIS 3 ATP
GLYCOLYSIS 6 2 NADH 6 ATP
GLYCOLYSIS 7 2 ATP 4- 2=2
GLYCOLYSIS 9 2 H2O
produce
GLYCOLYSIS 10 2 ATP
INTERMEDIATE 1 2 NADH 6 ATP 2CO2
KREB’s CYCLE 2 2 H2O
use
KREB’s CYCLE 5 2 NADH 6 ATP 2CO2
KREB’s CYCLE 6 2 NADH 6 ATP 2CO2
KREB’s CYCLE 7 2 GTP
KREB’s CYCLE 8 2FADH 4 ATP
KREB’s CYCLE 9 2 H2O
use
KREB’s CYCLE 10 2 NADH 6 ATP
TOTAL 2 use
ATP
6 ATP
produce
10 ETC
Cristae
2 ETC
Cristae
34 ATP 6
produce
38
ATP
For 1 Glucose Molecule:
GLYCOLYSIS = 1
Phosphorylation = 4
Dephosphorylation = 4
Oxidation = 2,
Dehydration = 2
Dehydrogenation = 12
INTERMEDIATE STEP = 2
Oxidation = 2
KREB’s CYCLE = 2
Oxidation = 8
ETC = 12
Light Reaction = 12
Water use = 12
Photolysis = 12
O atom produce = 12
ATP produce = 12
NADPH produce = 12
Cyclic = 6
Non cyclic = 12
Dark Reaction = 6
CO2 use = 6 REDUCTION = 6
15. offspring
Part of Cell Discovery Composition Functions
Cell Wall Robert Hooke Cellulose, hemicellulose, lignin,
pectin, silica, wax, salt
Protection, covering, prevent from osmotic lysis
Cell
Membrane
Schwann 60-80% proteins, 20-40% lipids,
glycogen, cholestol
Tranportation, passive transport, active transport, endocytosis,
phagocytosis, pinocytosis,
Cytoplasm H2O, enzymes, cytogel, cytosol,
ground, fundamental
substances
Metabolic pathway-glycolysis, cyclosis, taxis, store house of
chemicals, substrate phosphorylation
E.R Keith R Porter RER, SER, cisternae Protein synthesis, transportation, detoxification, Ca transport
Ribosome
Polysome
Palade rRNA, protein, 70S, 80S Protein synthesis by translation
GB C.Golgi Cisternae, lipid, protein, forming
and maturation face
cell secretions (secretory house), formation of granules, vesicles,
blebs, lysosomes
Lysosome D Duve lipid, protein, enzymes, Pri &
Sec lysosomes (autophagosome)
Digestion, autophagy, autolysis, digestive organ of cell
Storage Congenital Diseases, Glycogenosis, Tay Sach’s
Peroxisome D Dove lipid, protein, enzymes metabolism of peroxides, microbodies
Glyoxysome lipid, protein, enzymes metabolism of lipid, glyoxylate cycle , provide energy during seed
germination, microbodies
Vacuole lipid, protein,
Food Vacuole, contractile
vacuole, secretory vacuoles
Tonoplast, prevent from osmotic lysis, cell elongation, turidity,
Ψp, K, salt, food & starch, waste & extra water store.
Cytoskeleton Protein-actin, myosin,
tropomyosin, troponin, flagellin,
tubulin
Microtubules-assembly and disassembly spindle, formation of
cilia, flagella, basal bodies and centrioles.
Microfilaments- contain contractile actin protein, at plasma
membrane, cyclosis and amoeboid movements.
Intermediate filaments- maintain cell shape, cell shape and
integration of cellular compartments.
Centriole
Centrosome
Protein, nine microtubules with
triplet,
Location of furrowing formation during cell division (cytokinesis),
and help in cilia formation.
Mitochondria lipid, protein, enzymes, Cristae Power house of cell, Kreb’s cycle, ETC, chemiosmosis, oxidative
phosphorylation, photorespiration, rigor mortis
Plastids; Chloroplast,
Chromoplast, Leucoplast
lipid, protein, enzymes-Rubisco Photosynthesis-light&dark reaction (Calvin cycle), ETC,
chemiosmosis, photolysis, photorespiration,
photophosphorylation
Nucleus Robert Brown lipid, protein, enzymes-
nuclease, ligase
Controlling authority, contain nucleolus, chromosomes,
transcription, central (gene dogma)
PROMOTER SEQUENCE PROKARYOTES EUKARYOTES
TATAAT (TATA box) -10 -25
TTGACA (CAAT box) -35 -75, -70
19. MDCAT, NUMS, NTS, AMC, LDMCAT MCQ Test
i. The ability to maintain their internal conditions constant is ------------------
A) thermoregulation B) osmoregulation C) excretion D) homeostasis
i. The ability of an organism to regulate it fluid contents is --------------------
A) thermoregulation B) osmoregulation C) excretion D) homeostasis
i. Sweating is a ------------process.
thermoregulation B) osmoregulation C) excretion D) homeostasis
i. In dehydrated condition body need ------------------
A) water excretion B) water conservation C) evaporation D) osmoregulation
B) The major control center of cell during homeostasis is ------------
Nucleus B) cell membrane C) Brain D) Gene
The control center of cell is ------------
Nucleus B) cell membrane C) Brain D) Gene
The detoxification of ammonia to ------------require the precursor of ornithine.
A) citruline B) arginine C) urea D) drugs
In kidney nephron is closely associated with network of -----------------
A) Henle’s loop B) afferent arteriole C) efferent arteriole D) peritubular artery
In insects salt and water reabsorption takes place in the -----------------------
Flame cell B) nephridium C) malpighian tubules D) rectal gland
CRITICAL QUESTIONS:
I. Differentiate excretion/egestion?
II. Write the functions/significance of
counter current method?
III. Why hemodialysis is better than
peritoneal dialysis?
IV. How insulin is regulated during
metabolism?
V. Justify “Urea factory is Liver while
Urine factory is Kidney”.
VI. Justify “All endothermic are warm
blooded but all warm blooded are not
endothermic”.
VII. Why right kidney is below the left
kidney?
VIII.Why osmoconformers have less
biodiversity and evolution than
osmoregulators?
IX. Why marine water fish drink water
while fresh water fish eat water?
X. Write the medical use of
trimethylamine oxide?
XI. Why Gardner use autumn leaves as
fertilizer?
XII. Why metanephridium is superior to
pronephridium?
20. Exoskeleton Endoskeleton
i. It develops from ectoderm.
ii. It is inert and nonliving.
iii. It has poor regeneration.
iv. It needs ecdysis for growth.
v. It is present outside the soft parts.
It develops from mesoderm.
It is living and show homeostasis.
It has regeneration and growth.
It does not need ecdysis.
It is present inside the soft parts.
Primary Growth Secondary Growth
The growth due to apical meristematic tissue. The growth due to lateral meristematic tissue.
The length of plant increased The girth / diameter of plant increased.
It takes place in non woody parts It takes place in woody parts.
It is started from seed germination and remain
Throughout life.
It is only during maturity of woody plants.
It is rapid process It is slow process
e.g. in all plants from bryophyte to angiosperm It is only in dicot and gymnosperm
Smooth Muscle Cardiac Muscle Skeletal Muscle
i. earliest and simplest muscle heart muscle attach to skeleton
i. non-striated striated striated
i. uninucleated uninucleated multinucleated
i. spindle shape branched Elongated fibres
i. without intercalated disc with intercalated disc without intercalated disc
i. involuntary involuntary Voluntary except diaphragm
i. around viscera In heart wall Bicep, tricep
Tetanus Tetany
It is bacterial disease. It is nutritional disease.
It is caused by Clostridium tetani It is caused by deficiency of Ca
It causes stiffness of jaws and neck It causes loss of sensations
It can be treated by antibiotics It is treated by Ca nutrition
MITOSIS MEIOSIS
The type of cell division in which chromosomes
remain constant from parent to daughter cell.
The type of cell division in which
chromosomes reduced half from parent to
daughter cell.
It is present in both N and 2N cell. It is only in 2N cell.
It is present in somatic or vegetative cell It is only in germ line cell
It helps in growth and in asexual reproduction It helps in sexual reproduction
It takes place through out life It takes place only during gametes and spore
formation.
It is without crossing over The crossing over and recombination exit
There is no genetic variability. There is genetic variability and evolution.
It is same in male and female It is different in male and female
The resulting cells are 2 The resulting cells are 4
It is completed by single stage It is completed by two stages I & II
Error in mitosis produce tumor and cancer Error in meiosis cause non-disjunction and
syndromes.
Characters
ALGAE PLANTAE
Chlorophyta BRYOPHYTA TRACHEOPHYTA
ULVA Liver
wort
s
Moss Hornwor
ts
Psilosida Lycopsida Sphe
nops
ida
Pteropsida/Filicinae
Ancestor of
Plants
Marc
ha
ntia
Mus
Ci,
Fun
aria,
Bryopsida
Anthoce
ropsida
Anthoce
rus,
Psilotum Spike Moss
Club
Moss
Hors
e Tail
Equi
setu
m
Non
Seeded
Seeded
SPERMATO
PHYTES
Adiantum Gymno
Angiosper
m
Morphic isomorphic HETROMORPHIC
Fertilizati
on
Non
Embryop
hytes
EMBRYOPHYTES
Gametes isogamous HETROGAMOUS
Spore Iso/zoos
pore
ISOSPOROUS HETROSPOROU
S
iso Hetro
Habitat Aquatic Amphibious Terrestrial/Aquatic/Xerophyte/Halophytes
Vascular No No Xylem, Phloem
21. GLANDS/ORGAN HORMONES FUNCTIONS DISEASES
Hypothalamus
Posterior lobe of Pituitary Gland
ADH water reabsorption diabetes insipidus
Oxytocin parturition and suckling, let down milk sterility
Anterior lobe of pituitary gland STH, hGH
Human Growth Hormone
promote protein synthesis Gigantism
Acromegaly
Dwarfism
TSH rapid growth and development Goiter
Cretinism
ACTH stress e.g. cold, heat, pain, fright, infections disturbance of normal adrenal functions
FSH in Females follicle development and secretion of oestrogens Sterility, infertility
FSH in Male Development of the germinal epithelium of testis
and sperm production.
Sterility, infertility
Prolactin Stimulates milk production
LH / FSH stimulate oestrogen secretion,
ICSH in male stimulates the interstitial cells of testis to
secrete testosterone
Median lobe of pituitary gland MSH in pregnancy stimulates melanocytes in skin to
produce melanin, which darkens the skin
Addison's disease, Moon face
disease
Adrenal Glands ACTH, excess steroid cortical hormones metabolism Cushing's disease
Pancreas Insulin, Glucagon Metabolism of glucose diabetes mellitus
Thyroid Excess Thyroxin BMR (basal metabolic rate) Graves' disease
cardiac failure
Iodine Deficiency Growth, metabolism Goiter
Lack of Thyroxin
hypothyroidism
growth and development Cretinism
hypothyroidism Weight, growth Myxoedema
calcitonin Lower Ca+2 in blood Massive Bone
Parathyroid gland Parthormone
Under-activity
Increases Ca+2
twitches and convulsion, Take Ca+2 from bone
muscular tetany, osteoporosis
hypocalcaemia
Parthormone
Over-activity
Increases Ca+2 in blood Demineralization
Kidney stone
Adrenal Glands ACTH, Cortical Hormones Stress, metabolism, Addison's Disease
Animal Phylum/Sub-taxa
Flatworm Pltyhelminthes, Acoelomata
Tape worm (Segmented) Pltyhelminthes , Acoelomata
Roundworm Nematoda , Pseudocoelomata
Pinworm Nematoda , Pseudocoelomata
Pig worm (Ascaris) Nematoda , Pseudocoelomata
Hookworm Nematoda , Pseudocoelomata
Whipworm Nematoda , Pseudocoelomata
Threadworm Nematoda , Pseudocoelomata
Segmented worm Annelida, Protostome
Sandworm, Lugworm Annelida, Protostome
Earthworm Annelida, Protostome
Rag worm Annelida, Protostome
Shipworm, Pileworm Mollusca, Protostome
Silk worm (insect) Arthropod, Protostome
Slow worm, Blind worm Reptiles, Deuterostome
Acron worm Hemichordata, Deuterostome
Blood fluke Pltyhelminthes, Acoelomata
Liverfluke Pltyhelminthes, Acoelomata
Planaria Pltyhelminthes, Acoelomata
Leech Annelida, Protostome
Centipede Arthropod, Protostome
Millipode Arthropod, Protostome
Cray fish, Craw fish, Prawn Arthropod, Protostome
Cuttle fish Mollusca , Deuterostome
Star fish Echinodermata, Deuterostome
Fish (Pisces) Chordata, Deuterostome
Ring worm (Dermatophyte) Fungal disease
22. Scientists Discovery
Alois Alzheimer Alzheimer's disease
Aristotle Abiogenesis
August Weismann Cells are basically similar
Bradford movement of cilia
Camillo Golgi G. Complex
Callous Linnaeus binomial nomenclature
Darwin definition of instincts behavior
Charles Chamberland porcelain filters paper
De Duve Lysosome , Peroxisome
Ernst Hackel proposed a third kingdom Protista
E-Chatton suggested differentiating terms Procariotique & eu-cariotique
H. Huxley and A. F. Huxley Sliding filament model
Ivanowski TMV
Jean Baptist de-Lamarck Evolution,
Keith R. Porter E.R
Kohler Insight Learning
Lorenz Oken Cells are vesicle like structure in livings
Louis Pasteur Biogenesis
Lynn Margulis and Karlene Schwartz modified 5 kingdom classification
Palade Ribosome
Pavlov Conditioning or conditioned reflex type I
Richard Altmann Mitochondria (bioblast)
Robert Brown Discover Nucleus
Robert Hooke Discover cell, Micrographia
Robert Whittaker 5 kingdom system
Robert Koch Germ Theory
Rudolf Virchow Support Cell Theory, Glial cell discover,
Omnis cellula e cellula
SJ Singer and GL Nicolson Fluid Mosaic Model
Theodor Schwann and Schleiden Cell Theory
Thorndike and B.F. Skinner Operent conditioning reflex type II
Uexkull and Lorenz Sign Stimulus
Plant Cell Animal Cell
i. They contain cell wall They are without cell wall.
i. They contain chloroplast They are without chloroplast
i. They contain Glyoxisome They are without Glyoxisome
i. They are without centriole They contain centriole
i. They show photosynthesis They don’t show photosynthesis
i. Cytokinesis is by phragmoplast Cytokinesis is by furrow formation
i. They store starch They store glycogen
Prokaryotic Cell Euokaryotic Cell
i. The cell without nucleus The cell with nucleus
i. They are without membranous organelles They contain membranous organelles
i. Their cell wall contain murein Their cell wall contain cellulose
i. Their ribosome is 70S Their ribosome is 80S
i. They asexually divide by binary fission They asexually divide by binary fission and some other
methods of asexual reproduction
i. They sexually reproduce by conjugation They sexually reproduce by conjugation and some other
methods of sexual reproduction
i. They are unicellular and haploid They are unicellular, multicellular, haploid, diploid and
triploid.
i. They form endospore They form exospore
i. Archeobacteria, Bacteria, Cyanobacteria Plant cell, animal cell, man cell, protozoa