Entrez is a search engine developed by the National Center for Biotechnology Information (NCB) that allows users to search and retrieve data from over 20 integrated biological databases, including sequences, gene records, citations, and abstracts. It provides a single interface to access all linked information on genes and proteins. Users can perform text searches using Boolean operators and view results in various formats like FASTA and XML.

1. K.K.Gupta
Associate Professor
Department of Zoology
VBU

2. • Retrieval of huge and ever increasing
database is one of the important task for users
in bioinformatics
• Retrieval is the method of searching /recovery
/procure /obtain the desired database
ENTREZ is a search engine to
retrieve the desired Molecular
Biology database

3. • It is a molecular biology database and retrieval system
• Developed by NCBI
• Also known as an integrated database and its cross-referenced
• It is an entry point for exploring distinct but integrated data bases.
• Easy to uses and is highly convenient
• User don’t have to visit multiple database as it displays all the
links of information on single web page
• It allows text based search for a wide variety of data , such as
annotated genetic sequence information , citations , abstract full
papers
• It uses Boolean operator
• Websites -
www.ncbi.nlm.nih.gov/Entrez

4. • Entrez covers over 20 databases including the
complete protein sequence data from PIR-
International, PRF, Swiss-Prot, and PDB and
nucleotide sequence data from GenBank that
includes information from EMBL and DDBJ.
• Results may be viewed in various formats
inlcuding FlatFile, FASTA, XML, and others
A graphical interface provides easy visualization of complete
genomes or chromosomes, as well as biological annotation on
individual sequences.
Entrez also allows Batch downloads of large search results.

7. PROTOCOL
1
• Open goggle /chrome
• Type -Entrez /
2
• Select Entrez from upper panel
• Type any biological gene or protein
3
• Click search

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