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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 03 Issue: 01 | Jan-2016 www.irjet.net p-ISSN: 2395-0072
© 2016, IRJET | Impact Factor value: 4.45 | ISO 9001:2008 Certified Journal | Page 864
DETECTION OF BRAIN TUMOR BELOW 3MM USING NIR SENSOR
1S.LAKSHMI, 2B.JEGAJOTHI
1Student, EEE Department, Sriram Engineering college, Tamil Nadu, India
2Asst.Professor, EEE Department, Sriram Engineering college, Tamil Nadu, India
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - : Brain tumor is one of the most life-
threatening diseases and hence its detection should be fast
and accurate. This can be achieved by the execution of
automated tumour detection techniques on medical
images. Some the presently using medical imaging
techniques are MRI, CT, micro wave which cannot detect
below 3mm size can be detected using Near Infrared
imaging techniques
Key Words: Near infrared, medical imaging
I. INTRODUCTION.
The aim objective of this project to detect the brain tumor
using the near infrared imaging technology for tumor size
below 3mm which could not be detected using CT and MRI
images. It is an non-invasive methods of detecting tumors.
A brain tumor is a collection (or mass) of abnormal cells in
the brain. The skull is very rigid and the brain is enclosed,
so any growth inside such a restricted space can cause
problems. Brain tumors can be cancerous (malignant) or
non-cancerous (benign). The existing system are Magnetic
Resonance Imaging (MRI) depends on magnetic activity in
the brain and does not use X-rays, so it is considered more
safe than imaging techniques that do use X-rays. SPECT
uses gamma rays, which are characteristically more safe
than other imaging systems using alpha or beta rays. Both
PET and SPECT scans require the injection of radioactive
materials, but the half-lives of isotopes used in SPECT can
be more easily managed The exiting system of the project
uses the RADAR technology .Use the micro wave imaging
to detect the brain tumor .The draw back of the exiting
system is micro wave may damage the brain cell if the
level of the micro wave increased little bit.
II.PROPOUSED SYSTEM
Here instead of using radar technologies, a new Near
infrared imaging is proposed for the tumor detection in
brain .This NIR imaging uses the 780nm frequency IR LED
for imaging. The 780nm led transmitter and photo
detector led (Receiver) is used for the imaging .Which act
like an radar system and for accurate result, LSVM signal
processing techniques is used
III- NEAR-INFRARED SENSOR
It is a spectroscopic method that uses the near-infrared
region of the electromagnetic spectrum (from about
700 nm to 2500 nm). Typical applications include
pharmaceutical, medical diagnostics (including blood
sugar and pulse oximetry), food and agrochemical quality
control, and combustion research, as well as research in
functional neuroimaging, sports medicine & science, elite
sports training, ergonomics, rehabilitation, neonatal
research, brain computer interface, urology (bladder
contraction), and neurology (neurovascular coupling).
Fig1: proceses of NIR sensor
Common incandescent or quartz halogen light bulbs are
most often used as broadband sources of near-infrared
radiation for analytical applications. Light-emitting diodes
(LEDs) are also used; they offer greater lifetime and
spectral stability and reduced power requirements.[2]
The type of detector used depends primarily on the range
of wavelengths to be measured. Silicon-based CCDs are
suitable for the shorter end of the NIR range, but are not
sufficiently sensitive over most of the range (over
1000 nm). In GaAs and PbS devices are more suitable
though less sensitive than CCDs. In certain diode array
(DA) NIRS instruments, both silicon-based and In GaAs
detectors are employed in the same instrument. Such
instruments can record both UV-visible and NIR spectra
'simultaneously’. Many commercial instruments for
UV/vis spectroscopy are capable of recording spectra in
the NIR range (to perhaps ~900 nm). In the same way, the
range of some mid-IR instruments may extend into the
NIR. In these instruments, the detector used for the NIR
wavelengths is often the same detector used for the
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 03 Issue: 01 | Jan-2016 www.irjet.net p-ISSN: 2395-0072
© 2016, IRJET | Impact Factor value: 4.45 | ISO 9001:2008 Certified Journal | Page 865
instrument's "main" range of
interest.
Fig2:wave from of NIR sensor
IV. STFT FILTER
Segment the signal into narrow time intervals (i.e.,
narrow enough to be considered stationary) and take the
FT of each segment.Each FT provides the spectral
information of a separate time-slice of the signal,
providing simultaneous time and frequency information.
Choose a window function of finite length.Place the
window on top of the signal at t=0 Truncate the signal
using this window.Compute the FT of the truncated signal,
save results.Incrementally slide the window to the right .
window reaches the end of the signal
FIG3: Block diagram of proposed system
V. LSVM (Lagrangian Support Vector Machine)
Algorithm
Before stating our algorithm we define two matrices to
simplify notation as follows:
With these definitions the dual problem becomes
It will be understood that within the LSVM Algorithm, the
single time that is computed at the outset of the
algorithm, the SMW identity will be used. Hence only an
matrix is inverted. The LSVM Algorithm is based directly
on the Karush-Kuhn-Tucker necessary and sufficient
optimality conditions KTP for the dual problem
Fig4:signals from stft filter
By using the easily established identity between any two
real numbers (or vectors) and :
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 03 Issue: 01 | Jan-2016 www.irjet.net p-ISSN: 2395-0072
© 2016, IRJET | Impact Factor value: 4.45 | ISO 9001:2008 Certified Journal | Page 866
the optimality condition can be written in the following
equivalent form for any positive :
These optimality conditions lead to the following very
simple iterative scheme which constitutes our LSVM
Algorithm:
for which we will establish global linear convergence from
any starting point under the easily satisfiable condition:
Setting the gradient with respect to of this convex and
differentiable Lagrangian to zero gives
or equivalently:
which is equivalent to the optimality condition under the
assumption that is positive an not an eigenvalue
VI-DISCUSSION
Near-Infrared Imaging and Tumor Compared with CT, and
MRI, targeted NIR imaging, intraoperative x-ray
fluoroscopy, affords the combination of tumor specificity,
low cost, safety,and, simplicity without exposing patients
and personnel to ionizing
FUNCTION
The NIR sensor placed on the head phantom. the sensor
reading is preprocess ( amplifying the signal )The
filter(STFT) is applied to reduce the noise. The LSVM is
used separete the siganls Then tumour size is detecte
fig:5:result image of brain tumor
VII-CONCLUTION
A low powered, high accurate, high speed technique has
been presented for detecting the brain tumor less than
3mm. The performance of the NIR imaging has been
verified in a head imaging system where a brain tumour
was successfully detected in an artificial head phantom.
VIII-REFERENCES
1. Akcan M, Stroud MR, Hansen SJ, Clark RJ, Daly NL,
Craik DJ, et al: Chemical re -engineering of chlorotoxin
improves bioconjugation properties for tumor imaging
and targeted therapy. J Med Chem 54:782–787, 2011
2. Alander JT, Kaartinen I, Laakso A, Pätilä T, Spillmann
T, Tuchin VV, et al: A review of indocyanine green
fluorescent imaging in surgery. IntBiomed Imaging
2012:940585, 2012
3. Behbahaninia M, Martirosyan NL, Georges J, Udovich
JA, Kalani MY, Feuerstein BG, et al: Intraoperative
fluorescent imaging of intracranial tumors: a review. Clin
Neurol Neu-rosurg 115:517–528, 2013
4. Berger MS: Malignant astrocytomas: surgical aspects.
Semin Oncol 21:172–185, 1994
5. Borofsky MS, Gill IS, Hemal AK, Marien TP, Jayaratna I,
Krane LS, et al: Near-infrared fluorescence imaging to
facili-tate super- selective arterial clamping during zero-
ischaemia robotic partial nephrectomy. BJU Int 111:604–
610, 2013
6. Brandes AA, Tosoni A, Franceschi E, Reni M, Gatta G,
Vecht
C: Glioblastoma in adults. Crit Rev Oncol Hematol 67:139–
152, 2008
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 03 Issue: 01 | Jan-2016 www.irjet.net p-ISSN: 2395-0072
© 2016, IRJET | Impact Factor value: 4.45 | ISO 9001:2008 Certified Journal | Page 867
7. Byar DP, Green SB, Strike TA: Prognostic factors for
malignant
glioma, in Walker MD (ed): Oncology of the Nervous
System. Boston: Martinus Nijhoff, 1983, pp 379–395
8. Cahill RA, Anderson M, Wang LM, Lindsey I,
Cunningham
C, Mortensen NJ: Near-infrared (NIR) laparoscopy for
intraoperative
lymphatic road-mapping and sentinel node identification
during definitive surgical resection of early-stage
colorectal neoplasia. Surg Endosc 26:197–204, 2012
9. Crane LM, Themelis G, Pleijhuis RG, Harlaar NJ,
Sarantopoulos
A, Arts HJ, et al: Intraoperative multispectral fluorescence
imaging for the detection of the sentinel lymph node in
cervical
cancer: a novel concept. Mol Imaging Biol 13:1043–1049,
2011 (Erratum in Mol Imaging Biol 13:1050, 2011)

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Detection of Brain Tumor below 3mm Using NIR Sensor

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 03 Issue: 01 | Jan-2016 www.irjet.net p-ISSN: 2395-0072 © 2016, IRJET | Impact Factor value: 4.45 | ISO 9001:2008 Certified Journal | Page 864 DETECTION OF BRAIN TUMOR BELOW 3MM USING NIR SENSOR 1S.LAKSHMI, 2B.JEGAJOTHI 1Student, EEE Department, Sriram Engineering college, Tamil Nadu, India 2Asst.Professor, EEE Department, Sriram Engineering college, Tamil Nadu, India ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - : Brain tumor is one of the most life- threatening diseases and hence its detection should be fast and accurate. This can be achieved by the execution of automated tumour detection techniques on medical images. Some the presently using medical imaging techniques are MRI, CT, micro wave which cannot detect below 3mm size can be detected using Near Infrared imaging techniques Key Words: Near infrared, medical imaging I. INTRODUCTION. The aim objective of this project to detect the brain tumor using the near infrared imaging technology for tumor size below 3mm which could not be detected using CT and MRI images. It is an non-invasive methods of detecting tumors. A brain tumor is a collection (or mass) of abnormal cells in the brain. The skull is very rigid and the brain is enclosed, so any growth inside such a restricted space can cause problems. Brain tumors can be cancerous (malignant) or non-cancerous (benign). The existing system are Magnetic Resonance Imaging (MRI) depends on magnetic activity in the brain and does not use X-rays, so it is considered more safe than imaging techniques that do use X-rays. SPECT uses gamma rays, which are characteristically more safe than other imaging systems using alpha or beta rays. Both PET and SPECT scans require the injection of radioactive materials, but the half-lives of isotopes used in SPECT can be more easily managed The exiting system of the project uses the RADAR technology .Use the micro wave imaging to detect the brain tumor .The draw back of the exiting system is micro wave may damage the brain cell if the level of the micro wave increased little bit. II.PROPOUSED SYSTEM Here instead of using radar technologies, a new Near infrared imaging is proposed for the tumor detection in brain .This NIR imaging uses the 780nm frequency IR LED for imaging. The 780nm led transmitter and photo detector led (Receiver) is used for the imaging .Which act like an radar system and for accurate result, LSVM signal processing techniques is used III- NEAR-INFRARED SENSOR It is a spectroscopic method that uses the near-infrared region of the electromagnetic spectrum (from about 700 nm to 2500 nm). Typical applications include pharmaceutical, medical diagnostics (including blood sugar and pulse oximetry), food and agrochemical quality control, and combustion research, as well as research in functional neuroimaging, sports medicine & science, elite sports training, ergonomics, rehabilitation, neonatal research, brain computer interface, urology (bladder contraction), and neurology (neurovascular coupling). Fig1: proceses of NIR sensor Common incandescent or quartz halogen light bulbs are most often used as broadband sources of near-infrared radiation for analytical applications. Light-emitting diodes (LEDs) are also used; they offer greater lifetime and spectral stability and reduced power requirements.[2] The type of detector used depends primarily on the range of wavelengths to be measured. Silicon-based CCDs are suitable for the shorter end of the NIR range, but are not sufficiently sensitive over most of the range (over 1000 nm). In GaAs and PbS devices are more suitable though less sensitive than CCDs. In certain diode array (DA) NIRS instruments, both silicon-based and In GaAs detectors are employed in the same instrument. Such instruments can record both UV-visible and NIR spectra 'simultaneously’. Many commercial instruments for UV/vis spectroscopy are capable of recording spectra in the NIR range (to perhaps ~900 nm). In the same way, the range of some mid-IR instruments may extend into the NIR. In these instruments, the detector used for the NIR wavelengths is often the same detector used for the
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 03 Issue: 01 | Jan-2016 www.irjet.net p-ISSN: 2395-0072 © 2016, IRJET | Impact Factor value: 4.45 | ISO 9001:2008 Certified Journal | Page 865 instrument's "main" range of interest. Fig2:wave from of NIR sensor IV. STFT FILTER Segment the signal into narrow time intervals (i.e., narrow enough to be considered stationary) and take the FT of each segment.Each FT provides the spectral information of a separate time-slice of the signal, providing simultaneous time and frequency information. Choose a window function of finite length.Place the window on top of the signal at t=0 Truncate the signal using this window.Compute the FT of the truncated signal, save results.Incrementally slide the window to the right . window reaches the end of the signal FIG3: Block diagram of proposed system V. LSVM (Lagrangian Support Vector Machine) Algorithm Before stating our algorithm we define two matrices to simplify notation as follows: With these definitions the dual problem becomes It will be understood that within the LSVM Algorithm, the single time that is computed at the outset of the algorithm, the SMW identity will be used. Hence only an matrix is inverted. The LSVM Algorithm is based directly on the Karush-Kuhn-Tucker necessary and sufficient optimality conditions KTP for the dual problem Fig4:signals from stft filter By using the easily established identity between any two real numbers (or vectors) and :
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 03 Issue: 01 | Jan-2016 www.irjet.net p-ISSN: 2395-0072 © 2016, IRJET | Impact Factor value: 4.45 | ISO 9001:2008 Certified Journal | Page 866 the optimality condition can be written in the following equivalent form for any positive : These optimality conditions lead to the following very simple iterative scheme which constitutes our LSVM Algorithm: for which we will establish global linear convergence from any starting point under the easily satisfiable condition: Setting the gradient with respect to of this convex and differentiable Lagrangian to zero gives or equivalently: which is equivalent to the optimality condition under the assumption that is positive an not an eigenvalue VI-DISCUSSION Near-Infrared Imaging and Tumor Compared with CT, and MRI, targeted NIR imaging, intraoperative x-ray fluoroscopy, affords the combination of tumor specificity, low cost, safety,and, simplicity without exposing patients and personnel to ionizing FUNCTION The NIR sensor placed on the head phantom. the sensor reading is preprocess ( amplifying the signal )The filter(STFT) is applied to reduce the noise. The LSVM is used separete the siganls Then tumour size is detecte fig:5:result image of brain tumor VII-CONCLUTION A low powered, high accurate, high speed technique has been presented for detecting the brain tumor less than 3mm. The performance of the NIR imaging has been verified in a head imaging system where a brain tumour was successfully detected in an artificial head phantom. VIII-REFERENCES 1. Akcan M, Stroud MR, Hansen SJ, Clark RJ, Daly NL, Craik DJ, et al: Chemical re -engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. J Med Chem 54:782–787, 2011 2. Alander JT, Kaartinen I, Laakso A, Pätilä T, Spillmann T, Tuchin VV, et al: A review of indocyanine green fluorescent imaging in surgery. IntBiomed Imaging 2012:940585, 2012 3. Behbahaninia M, Martirosyan NL, Georges J, Udovich JA, Kalani MY, Feuerstein BG, et al: Intraoperative fluorescent imaging of intracranial tumors: a review. Clin Neurol Neu-rosurg 115:517–528, 2013 4. Berger MS: Malignant astrocytomas: surgical aspects. Semin Oncol 21:172–185, 1994 5. Borofsky MS, Gill IS, Hemal AK, Marien TP, Jayaratna I, Krane LS, et al: Near-infrared fluorescence imaging to facili-tate super- selective arterial clamping during zero- ischaemia robotic partial nephrectomy. BJU Int 111:604– 610, 2013 6. Brandes AA, Tosoni A, Franceschi E, Reni M, Gatta G, Vecht C: Glioblastoma in adults. Crit Rev Oncol Hematol 67:139– 152, 2008
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 03 Issue: 01 | Jan-2016 www.irjet.net p-ISSN: 2395-0072 © 2016, IRJET | Impact Factor value: 4.45 | ISO 9001:2008 Certified Journal | Page 867 7. Byar DP, Green SB, Strike TA: Prognostic factors for malignant glioma, in Walker MD (ed): Oncology of the Nervous System. Boston: Martinus Nijhoff, 1983, pp 379–395 8. Cahill RA, Anderson M, Wang LM, Lindsey I, Cunningham C, Mortensen NJ: Near-infrared (NIR) laparoscopy for intraoperative lymphatic road-mapping and sentinel node identification during definitive surgical resection of early-stage colorectal neoplasia. Surg Endosc 26:197–204, 2012 9. Crane LM, Themelis G, Pleijhuis RG, Harlaar NJ, Sarantopoulos A, Arts HJ, et al: Intraoperative multispectral fluorescence imaging for the detection of the sentinel lymph node in cervical cancer: a novel concept. Mol Imaging Biol 13:1043–1049, 2011 (Erratum in Mol Imaging Biol 13:1050, 2011)