Canine Coronavirus Infection was first recognized in 1971 and there are two genetically distinct forms. The virus is highly contagious and spreads through feces. It infects the small intestine and causes damage to the villi, preventing nutrient absorption. Infections are usually mild but simultaneous infection with CPV can cause more severe illness with mortality approaching 90% in puppies. Diagnosis is based on symptoms of vomiting, diarrhea, and fever and confirmed with virus detection in feces by antigen detection tests or electron microscopy. Treatment is supportive and recovery typically occurs within a week. Vaccines are available to protect against CCV.

5. Molecular Biology