This document provides an overview of ubio's product portfolio for 2012. It describes ubio as a company developing affordable, accurate and accessible diagnostics for human, veterinary and food applications. The document lists ubio's rapid test products for infectious diseases, cancer, fertility, drug of abuse and forensics for human diagnostics. It also lists veterinary rapid tests for bovine, canine, avian, feline and other applications. The document provides details on ubio's raw materials including lateral flow components, colloidal gold/silver, conjugates and nanoparticles. It positions ubio as a provider of complete diagnostic solutions from research to manufacturing.
Innovative Drug Pipeline Solutions: Medicinal Chemistry, Process Chemistry, cGMP API Manufacturing. 105+ global clients. 120,000 sq.ft. facilities located in Research Triangle Park, NC USA. FDA inspected and DEA registered.
Innovative Drug Pipeline Solutions: Medicinal Chemistry, Process Chemistry, cGMP API Manufacturing. 105+ global clients. 120,000 sq.ft. facilities located in Research Triangle Park, NC USA. FDA inspected and DEA registered.
In this presentation, Joseph Campos of Children’s National Medical Center discusses healthcare and laboratory testing using Lean, and the 5 Lean principles that apply to the laboratory. He shares three case studies from his lab: microbiology lab workload and staffing data, microbiology incoming work cell and automated culture plate inoculation. Joe also discusses the difference between and traditional approach to microbiology testing versus a Lean approach.
TetraQ - Integrated Preclinical Drug Development Solutions Presentationguest55305
TetraQ is a leading Australian preclinical contract research organization focused on providing a broad range of integrated preclinical drug development solutions in the disciplines of ADME, Bioanalytics, Efficacy, Toxicology and Pharmaceutics. TetraQ’s Toxicology, ADME and Bioanalytics laboratories are GLP recognised and in collaboration with NATA, TetraQ’s ADME team pioneered ISO17025-2005 (R&D) research & development accreditation becoming the first laboratory in Australia to obtain this accreditation in 2005.
Each of our world-class facilities is equipped with state-of-the-art instrumentation including LC-MS/MS, HPLC & ELISA. Essentially, TetraQ is a one-stop-shop for early stage drug development and we are recognized as world leaders in bioanalytical method development & sample analysis of drugs / metabolites in biological fluids with both human and animal samples.
Excipients selection for high risk formulations Smita RajputMerck Life Sciences
Are you choosing the right excipients for your high risk application? Find out how to select the right excipients and enable your process optimization to improve the total cost of ownership.
In this webinar, you will learn:
• Selection of right excipients for high risk formulation is very critical step
• Low Endotoxin and low bioburden limits are important aspect while selecting raw materials
• Strong regulatory support is crucial for high risk formulation
Excipients selection for high risk formulations like parenteral and ophthalmic applications is very challenging. Excipients should be inert with high purity for such dosage forms because trace amounts of impurities present in excipients can interact with active pharmaceutical ingredient (API) which results in instability of the formulation. This presentation discusses how to select the right excipients for high-risk applications and gives guidance for process optimization by choosing the best combination of filters and excipients to improve the total cost of ownership.
In this presentation, Joseph Campos of Children’s National Medical Center discusses healthcare and laboratory testing using Lean, and the 5 Lean principles that apply to the laboratory. He shares three case studies from his lab: microbiology lab workload and staffing data, microbiology incoming work cell and automated culture plate inoculation. Joe also discusses the difference between and traditional approach to microbiology testing versus a Lean approach.
TetraQ - Integrated Preclinical Drug Development Solutions Presentationguest55305
TetraQ is a leading Australian preclinical contract research organization focused on providing a broad range of integrated preclinical drug development solutions in the disciplines of ADME, Bioanalytics, Efficacy, Toxicology and Pharmaceutics. TetraQ’s Toxicology, ADME and Bioanalytics laboratories are GLP recognised and in collaboration with NATA, TetraQ’s ADME team pioneered ISO17025-2005 (R&D) research & development accreditation becoming the first laboratory in Australia to obtain this accreditation in 2005.
Each of our world-class facilities is equipped with state-of-the-art instrumentation including LC-MS/MS, HPLC & ELISA. Essentially, TetraQ is a one-stop-shop for early stage drug development and we are recognized as world leaders in bioanalytical method development & sample analysis of drugs / metabolites in biological fluids with both human and animal samples.
Excipients selection for high risk formulations Smita RajputMerck Life Sciences
Are you choosing the right excipients for your high risk application? Find out how to select the right excipients and enable your process optimization to improve the total cost of ownership.
In this webinar, you will learn:
• Selection of right excipients for high risk formulation is very critical step
• Low Endotoxin and low bioburden limits are important aspect while selecting raw materials
• Strong regulatory support is crucial for high risk formulation
Excipients selection for high risk formulations like parenteral and ophthalmic applications is very challenging. Excipients should be inert with high purity for such dosage forms because trace amounts of impurities present in excipients can interact with active pharmaceutical ingredient (API) which results in instability of the formulation. This presentation discusses how to select the right excipients for high-risk applications and gives guidance for process optimization by choosing the best combination of filters and excipients to improve the total cost of ownership.
Dear Sir,
I take pleasure in introducing STABICON LIFE SCIENCES, a focused Analytical Methods Development/Validation & Stability Centre.
Stabicon Life Sciences is a Contract Research Organization. Services provided by Stabicon currently include specialized and focused services for complete stability study management including storage of samples, analysis and preparation of required documentation, associated analytical method development and validations for different phases of drug development program.
We are committed to complete confidentiality and protection of client’s intellectual property. We are committed to quality and reliability of our service. We also remain committed to our customers to deliver on agreed objectives and committed timelines and a promise to ourselves to be a reliable partner fulfilling requirements of our customer’s .Now we have been approved by few National & Multinational companies, who have now placed order with us for conducting stability studies on their products. We have been audited on behalf of Health Canada and have been approved for performing analytical and stability work for Canadian companies. We are also in process getting registration of our company with USFDA as cGMP testing analytical company located outside United States.
We have come across your company as a reputed organisation.We are looking for business partners with whom we can associate by acting as your back office support from India. By doing this it will allow you to allocate your resources for strategic projects. It will also allow you to save on your budgets significantly by taking advantage of Indian costs with International Quality Services offered by Stabicon.You may please visit our website www.stabicon.com for more details.
Looking forward to your response.
Thanking you and assuring our best service at all time.
Regards,
Vijay
Project Director
Stabicon Life Sciences Pvt Ltd
Mobile: +919591974355/080-41714280
www.stabicon.com
The company born in 1994 in Salamanca,
In order to give service to the food-processing sector.
Nowadays, our actuation's field is Spain and Portugal.
Technical Food consultancy, Laboratory of
analysis for the integral service of Assistance, Quality control, Evaluation and Training.
Fully-Integrated Services for Global Therapeutics Development: Accelerating Progress and Time to Market with integrated CDMO Platforms and Laboratory Testing Services. WuXi Advanced Therapies leverages decades of laboratory testing experience to get your product to market faster and with greater predictability, by overcoming common industry constraints.
Bhat Bio-Tech India (P) Ltd was incorporated in the year1994 and carved a niche as the known manufacturers and suppliers of Healthcare products for Malaria, HIV, HBsAg, HCV, Syphilis, Chikungunya, Dengue, LH,hCG Card, Glucometer, Blood Test Strips, Urine Test Strips and many more products. Our products are widely known for the features such as superior quality, reasonable prices. Manufactured from superior quality material our range stands high in terms of quality.
Thermo Fisher Scientific India Pvt. Ltd. (NYSE: TMO) is the world leader in serving science, with revenues of $18 billion and approximately 55,000 employees globally. Our mission through our premier brands Thermo Scientific, Applied Bio Systems, Invitrogen, Fisher Scientific and Unity Lab Services, we offer an unmatched combination of innovative is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. We offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support.
A Novel approach for quantitative real-time particle analysis of lentiviral v...Myriade
Lentiviral vectors are efficient vehicles for stable gene transfer in dividing and non-dividing cells. They tend to be increasingly used as a powerful tool to introduce genes into cells ex vivo, for instance in CAR-T cell therapies.
During manufacturing and production of lentiviral vectors, relevant quality control is necessary to allow batch release (1). Among standard quality control methods that can be used, quantification of lentiviral vector particles – or physical titer – is one of the most important. Up to now, this characterization can be achieved either indirectly with p24 protein quantification or with physical methods like Tunable Resistive Pulse Sensing (TRPS) for example, both methods implying prior preparation of samples (lysis, dilution or filtration). These two methods thus show important limitations as they cannot accurately reflect the true nature of the product, in addition to being relatively time-consuming (2).
Myriade, a French company created in 2017, is developing Videodrop, a new optical technique performing real-time, user-friendly, and label-free measurement of lentiviral vector physical titer. This method, based on full-field interferometry (3), was tested on various lentiviral vector samples: in a context of Drug Product (DP) release as well as in-process controls.
We compared three lentiviral physical titration methods on aratinga.bio productions: p24 ELISA, qNano and Videodrop – Myriade instrument. The correlation between Videodrop analysis and the other two methods appeared to be robust, with high R² values. These results suggest that Myriade technology is relevant for DP release as well as in-process controls, offering the ability to be a tool for continuous improvement. It is an easy-touse and fast alternative to the standard more complex and time-consuming physical titration methods.
White Paper : Need for Standardization of Tests for Plant Viruseskrishgen
Plant virus testing in India requires standardization. There is a need for Department of Biotechnology, under the Ministry of Agriculture to work towards encouraging Indian manufacturers to develop and offer test kits at low costs suited to Indian farmers.
#InvitroStudies are critical to the #drug and #wellness product #development due to their ability to provide a basis for #clinical in vivo studies for predicting best delivery model to take Go/No-Go decision. #Our solution on in vitro analyses can provide proof of concept on delivery dosage form in the early stages or reverse pharmacology #development of the active process, when the selectively and possible interactions of the active process, when the selectivity and possible interactions of the candidate drug towards the desired therapeutic target are established. Our team can provide solution map on case to case basis for your specific requirement . For more details please visit on https://www.stabicon.com/In-Vitro.php
The ubio sensit Filaria antibody Rapid Test is a lateral flow immunoassay for
detection of anti-lymphatic filarial parasites (W. Bancrofti and B. Malayi) in human whole blood, plasma or serum. This test is intended to be used as a screening test and as an aid in the diagnosis of infection with lymphatic filarial parasites.
Cattle pregnancy test for rapid early detection of pregnancy in cow
ubio quickVET pregnancy detection test provides a perfect tool to detect non-pregnancy in cattle accurately within 21 days. The kit provides 100 percent detection of non-pregnant cases and allows insemination at the first opportunity. The test can be easily performed within 20 minutes at cow-side without any instrumentation, which makes the tool attractive even for direct use by dairy farmersCattle pregnancy test for rapid early detection of pregnancy in cow
ubio quickVET pregnancy detection test provides a perfect tool to detect non-pregnancy in cattle accurately within 21 days. The kit provides 100 percent detection of non-pregnant cases and allows insemination at the first opportunity. The test can be easily performed within 20 minutes at cow-side without any instrumentation, which makes the tool attractive even for direct use by dairy farmers
One of the main challenges for a versatile application of monitoring technologies in the
veterinary and food industry is to develop fast, quantitative and low cost devices that
can be used with minimal expertise. Most of the diagnostic technologies in use today
require laboratory facilities, expensive equipments and trained personnel. During the
last decade, a few technologies have been proposed and developed that fulfill most
requirements of versatility mentioned above. One of the most promising approaches is
the lateral flow immunoassay technique.
The first presentation in the ubio exclusive series ‘Biology for Computer Engineers’, gave an introduction to biochemistry basics and covered protein biochemistry. The second presentation in the series focuses on cells, which are the basic life forms. It provides short introduction to biochemistry of nucleic acids and lipids and explains the concept of ‘life’ and its evolution. It then goes on to discuss biology of the cell, especially cell structure and cell functions.
As in the previous presentation, the focus of this cell biology ppt is on highlighting the thread of common logic that runs beneath the enormous diversity of life forms, while giving an overview of biochemistry and cell biology. Future editions of our molecular biology articles will feature genetic biotechnology, bioinformatics and computational biology.
ubio is starting a series of biology tutorials aimed at introducing biology, biotechnology and bioinformatics to computer engineers. The first part of the presentation is essentially a biochemistry tutorial that introduces molecular biochemistry.
This document is the summary of my thesis work carried out at Indian Veterinary Research Institute, Izatnagar, India (2001)
I am sorry, I cant provide a download option for this
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
2. 2012
COMPANY PROFILE
ubio is a young, vibrant venture developing innovative solutions in medical, veterinary and food diagnostics. We leverage the latest and best technologies
from the fields of electronics, information technology, and biotechnology to create products and solutions that take hi-tech diagnostics to the mass-market.
ubio’s vision is Affordable, Accurate, Accessible Diagnostics for All.
ubio’s mission is to develop high-quality diagnostic products and make them accessible to
everyone at low cost, while creating value for its customers, employees, investors and partners.
ubio's product portfolio includes low-cost rapid tests for human, veterinary and food
diagnostics that make diagnostics affordable and accessible to patients, farmers and small
industries without any capital investment. We have also developed a new generation biochip
for clinical diagnostics market that will provide high quality test assays at significantly lower
price points.
Headquartered at Cochin, Kerala, India, ubio brings together key scientific and engineering
talent with experience in the cutting-edge of biotechnology, information technology and
electronics. Our technology leaders have proven expertise in product development and
management, and have made major contributions to software and biotechnology industries.
ubio was established in 2008 and the R&D laboratory and Manufacturing Facilities are located
at Kinfra Biotechnology Park, in Kerala. The GMP and ISO 13485 certified manufacturing
facility is approved by Indian Drug Regulatory authorities for the manufacture of IVDs. The R&D
facility of ubio is approved by Department of Scientific and Industrial Research, Government of
India.
GMP
CERTIFIED
ubio Business Profile
Veterinary and Food
Medical IVD Tests Contract Manufacture Contract Research
Tests
Companion Animal Lateral-flow tests Diagnostic tests
Infectious Diseases development
Tests
•ELISA, Lateral-flow,
LAT, PCR etc.
ELISA kits
Cancer and Cardiac Livestock Recombinant
Tests Diagnostics protein and
Latex Agglutination antibody
tests development
Drug of Abuse and Antibiotic and toxin
Raw Materials and
Fertility Products residues PCR tests uncut sheets
3. 2012
HUMAN
DIAGNOSTICS
The sensit tests are one-step Immuno-chromatographic assays for the
detection of antigen or antibodies in human Blood, serum, plasma or other body
fluids.
These rapid tests are inexpensive, disposable, membrane based RAPID
assays that provides visual evidence of the presence of an analyte in ONE STEP
clinical samples. The test uses colloidal gold conjugated antigen or POINT –OF-CARE
antibodies for visualisation of the results. The test kit consists of a
plastic cassettes containing a membrane strip. The
base substrate of the test is usually a nitrocellulose
membrane in which the test and control
Positive
antigen/antibodies are printed at specific locations. A
conjugate pad, a glass fibre sheet is attached to this
strip which contains dried gold conjugates. A sample
pad and absorbent pad are attached each ends, one act as sample Negative
wick and the other as sink.
The results are available within
When the sample is added to the sample pad, it will move 20 minutes.
Suitable for testing in low
towards the gold conjugate pad, re-hydrating the gold conjugate
resource setting.
and allowing the interaction of sample analyte with the conjugate. Portable, no need of equipment.
Results are comparable to ELISA
The complex of gold conjugate and analyte then moves onto the or other gold standards.
membrane strip and migrate towards the capture proteins printed Stable at room Temperature upto
2 years
on Test Line. The binding of gold conjugate complex will produce an
intense red line at the test line. A second line is also formed at the
control line region by the excess gold conjugate.
4. 2012
ubio SENSIT Rapid Tests
Tropical Diseases Malaria Products
Filariasis Antibody Test Malaria Antigen Test
Lateral flow Immunoassay for anti Wuchereria bancrofti These tests detect Plasmodium falciparum HRP antigen and/or
and Brugia malayi antibodies in human Blood, serum or Plasmodium vivax/Pan LDH antigen in Whole blood.
plasma. Malaria Pf HRP/Pan LDH Antigen test
Leishmaniasis Antibody Malaria Pf HRP/Pv LDH Antigen test
One step Immuno qualitative detection of antibodies to Malaria Pf HRP Antigen test
members of L. donovani complex in human serum.
Malaria Pan LDH Antigen test
Available as strips and cassette (whole blood).
Typhoid IgM Malaria Pv LDH Antigen test
Lateral flow assay for the specific detection of Salmonella
Typhi specific IgM antibodies in Human Blood, serum or Malaria Antibody Test
Plasma One step immuno-chromatographic assay for detection of
Brucella IgG Pv/Pf MSP and CSP specific antibodies of all isotypes (IgA, IgG
Lateral flow assay for detection of IgG response of and IgM) in Human blood, serum or Plasma
Brucella abortus, Brucella melitensis and brucella suis
infection in human. Enteric infections
Leptospira IgM Rota-Adeno Antigen test
IgM lateral flow assay for Human Leptospirosis. The test is Rapid immuno-chromatographic assay for detection of Rota
able to detect all serovars of Leptospira that causes and Adeno virus antigens in human stool in acute gastro
leptospirosis in humans. enteritis cases.
Human TB antigen tests H Pylori Antibody
H.pylori test is a rapid test for the qualitative detection of
MPT 64 Antigen test antibodies of all isotypes (IgG, IgM, IgA, etc.) specific
One step Immuno-chromatographic assy for the detection to Helicobacter pylori in human serum, plasma or whole blood
of MPT 64 Tb antigen in culture fluids and solid cultures.
H Pylori Antigen Test
TB LAM Test H.pylori Ag test is a rapid test for the qualitative detection
Mycobacterium tuberculosis and bovis specific of Helicobacter pylori antigen in human fecal specimen.
Lipoarabinomannan antigen detection test for culture
fluids. (also can be used for sputum testing) Fertility Hormones
Contract manufacturing and Loan licensing LH test
options. Home ovulation test for detection of Luteinising Hormone in
Tests are available is 1 test, 10 tests, 25, 30 and human urine.(25mIU/ml)
50 tests
OEM options hCG
Home urine pregnancy test for detection of human chorionic
Products are available as uncut sheets
Gonadotropins in Human urine. (10mIU/ml). Available as Card
and Strips
5. 2012
VETERINARY
DIAGNOSTICS
Animal Health Diagnostics ubio quickVET Rapid Tests
One step Immuno-chromatographic
Bovine Tests Canine Rapid Tests
assays Bovine TB Rapid Test
Bovine Brucella Rapid test Canine Parvovirus Antigen Test
Accurate Bovine TB-Brucella Combo Test Canine Distemper Virus antigen Test
Bovine FMD NSP Rapid test* Canine Corona Virus antigen test
High sensitive and good correlation Bovine Anaplasma Ab Rapid test. CPV-CCV Combo test
with other test method FMD antigen Rapid test.* Canine Adeno virus antigen test
Rota Virus Test Canine Ehrlichia Rapid test
Rabies virus antigen test Canine Lyme Antibody test
Anywhere
Bovine Viral Diarrhoea antigen test Canine Leptospira IgM test
Bovine pregnancy Rapid Test Canine Leishmania Antibody test
- Laboratory, Farm, Clinic, Home: Bovine Theilaria Rapid Test* Canine Brucella antibody test
No equipment needed Bovine Babesia rapid test.* Ag/Ab Rabies Antibody test
Bovine-Haemo-Protozoan Panel*
Simple Infectious Bovine Rhino-Tracheitis
Ab test
- One Step after collection a sample Bovine leukaemia Virus Ag Test
Bovine Leukaemia Test Ab test
Fast Neospora Antibody test
- Reliable Result within 10 min. Swine Tests Avian
Swine Brucella IBD antigen test
Swine FMD* NDV antigen test
Immediate
Echinococcus antibody test Marek’s Disease Antigen test
Porcine Corona Virus antigen test Infectious Bronchitis Antigen test
- Treatment and Avian Influenza antigen Test
PRRSV antigen Test
Management(vaccination, Classical Swine Fever Ag Test Avian antibody Tests:
quarantine) after identifying the TGEV antigen test. Avian Leukosis Virus Antigen
cause Pseodo-rabies(Ajeskey’s disease)
Antigen test
Rabies products Feline
Self
Rabies antigen tests Feline Toxoplasma Antibody test
Rabies FITC conjugate FeLV antigen Test
- Self testing by Pet owner or Rabies ELISA kit FIV antibody test
Farmer themselves FIV-FeLV Combo
Feline Parvo Rapid Test
Low cost Ovine Tests Fish/ Aquatic
Brucella ovis Rapid test WSSV lateral Flow*
- Time, Labor, Money saving Aeromonas caviae
Stenotrophomonas maltophilia
*under development
* coming soon
Positive
Negative
6. 2012
DRUG OF ABUSE*
A drug test is a technical analysis of a biological specimen – for example urine, hair,
blood, sweat, or oral fluid / saliva – to determine the presence or absence of specified
parent drugs or their metabolites. Major uses of drug testing are to detect the presence
of performance enhancing steroids in sport or for drugs prohibited by laws, such as
cannabis, cocaine and heroin. The drug abuse may lead to health problems, Social
problems, Physical dependence or psychological addiction
Product Target Compound Cut-Off levels(ng/ml)
AMP Amphetamine 1000 ng/ml
BAR Barbital 300 ng/ml
BZO Benzodiazepine 300 ng/ml
BUP Buprenorphine 10 ng/ml
COC Cocaine 300 ng/ml
KET Ketamine 300 ng/ml
MDMA Methylenedioxymethamphetamine 1000 mg/ml
MTD Methadone 300 ng/ml
MET Methamphetamine 1000 ng/ml
MOR Morphine 300 ng/ml
OXY Oxycodone 300 ng/ml
PCP Phencyclidine 25 ng/ml
PPX Propoxyphene 300 ng/ml
TCA Tricyclic Antidepressants 1000 ng/ml
THC Tetrahydrocannabinol 50 ng/ml
DOA-Multi Test Combination 2 or more tests
Human Blood stain Tests*
One step Immuno-chromatographic test to detect haemoglobin
residues in human blood and Blood stains
Semen test*
FORENSIC One step Immuno-chromatographic test to detect Prostate
Specific Antigen presence in human semen or semen stains
Note: these Products are available only on OEM and on Bulk orders.
7. 2012
RAW MATERIALS &
FOOD
DIAGNOSTIC
DIAGNOSTICS
REAGENTS
LATERAL FLOW RAW MATERIALS
Uncut Sheets(Master Sheets)
Uncut sheets of all the rapid tests are available. The standard size is 300X60mm. custom sizing and
membrane type is possible for a minimum order of 20 sheets.
Colloidal gold
Colloidal gold for various application like manufacture of rapid IVD kits, Cat. No Spec
Immuno electron microscopy application. UCG10000 10 liters
Available in sizes from 5nm, 10nm, 15, 20, 25, 30 and 40nms. UCG1000 1000ml
Supplied unconjugated with or without preservatives UCG100 100ml
UCG10 10ml
Colloidal silver
Colloidal silver for various application like manufacture of Lateral Cat. No Spec
Flow Assays UCS10000 10 liters
UCS1000 1000ml
UCS100 100ml
UCS10 10ml
Colloidal gold Conjugates
Colloidal gold conjugated with antibodies, usually at a rate of 10-30microgram per ml of gold. Available in
various ODs.
Anti-Human IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0101 1mg
UCG0102 5mg
Anti-Rabbit IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0201 1mg
UCG0202 5mg
Anti-Mouse IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0301 1mg
UCG0302 5mg
Anti-Goat IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0401 1mg
UCG0502 5mg
Anti-Bovine IgG
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0501 1mg
UCG0602 5mg
Anti-BSA IgG
8. 2012
40nm colloidal gold conjugated to affinity purifies rabbit anti human IgG. Cat. No Spec
Supplied in Tris-Buffer with sodium azide preservative. UCG0601 1mg
UCG0602 5mg
Protein A
40nm colloidal gold conjugated to purified recombinant protein A(30µg/ml of Cat. No Spec
gold). Supplied in Tris-Buffer with sodium azide preservative. UCG0701 10mg
UCG0702 100mg
Protein G
40nm colloidal gold conjugated to purified recombinant protein G(30µg/ml of Cat. No Spec
gold). Supplied in Tris-Buffer with sodium azide preservative. UCG0801 1mg
UCG0902 10mg
UCG0903 100mg
Protein A/G
40nm colloidal gold conjugated to purified recombinant protein A/G(30µg/ml of Cat. No
gold). Supplied in Tris-Buffer with sodium azide preservative. UCG1001 10mg
UCG1002 100mg
Nano-particles
CdSe quantum dot Particle These are suitable for
CdS Quantum dot Particle quantum dot based
ZnO Quantum dot Particle diagnostics.
Fe3O4 Ferro-liquid /FePt Ferro-liquid
Magnetic beads suitable for magnetic bead separations
ELISA Reagents
TMB: Soluble
TMB - This aqueous non-hazardous liquid substrate for peroxidase consists of Tetramethylbenzidine Cat. No Spec
(TMB) plus dilute hydrogen peroxide in a single-reagent stabilized form. The reagent has been
specifically formulated for measuring peroxidase in ELISA systems which is stable for long-term
UER-CT-01 125ml
storage providing sensitivity greater than OPD. This reagent is available as a single component, UER-CT-02 500ml
ready-to-use reagent. When used in conjunction with our proprietary TMB Stop Buffer (TSB), the UER-CT-03 1000ml
resulting color product will not fade or darken for several hours. Our TMB products have built a
UER-CT-04 20Liters
reputation for robust performance, unparalleled stability and next to zero lot-to-lot variation. Each
TMB formulation can be specifically engineered to meet the needs of your specific assay
TMB Membrane
This liquid substrate for peroxidase consists of tetramethylbenzidine (TMB) plus dilute hydrogen Cat. No Spec
peroxide in a single-reagent stabilized form. The reagent has been specifically formulated for
measuring peroxidase in EIA systems. This reagent is stable for long-term storage, and provides
UER-CTP-01 125ml
sensitivity equal to, or greater than, that of other commercially available chromogens. UER-CTP-02 500ml
UER-CTP-03 1000ml
UER-CTP-04 10Liters
DAB One-Component Solution (3,3'-Diaminobenzidine)
his reagent produces a crisp, clean, very intense stain that is free of unwanted background. When in Cat. No Spec
the presence of peroxidase, DAB produces a brown precipitate that is insoluble in alcohol. Stained
slides may be mounted in any commercially available mounting media. This product is stable
UER-DAB-01 125ml
for 2-3 months. UER-DAB 02 500ml
UER-DAB-03 1000ml
TMB Stop buffer
ubio's Stop Buffer (TSB) offers a unique combination of acid that produces a more stable stopped Cat. No Spec
reaction product than other formulations of H2SO4 or HCL. Stopped reactions show increased
absorbance values of approximately two-fold over unstopped reactions with minimal drift for up to
UER-SBT-01 125ml
six hours depending on various conditions. UER-SBT-02 500ml
UER-SBT-03 1000ml
UER-SBT-04 20Liters
BCIP-NBT: soluble
5-Bromo-4-Chloro-3-Indolyl Phosphate/nitroblue Tetrazolium (BCIP/NBT) Solution. Is a widely used Cat. No Spec
chromogen for immunohistochemical and in-situ staining. This reagent is available as a single
component, ready to-use reagent. When in the presence of the Alkaline-Phosphatase enzyme,
UER-NBT-01 125ml
9. 2012
BCIP/NBT produces a purple precipitate that is soluble in alcohol. UER-NBT-02 500ml
UER-NBT-03 1000ml
UER-NBT-04 20Liters
ELISA Coat Stabiliser
Coating Stabilizer has been developed specifically for the stabilization of adsorbed or immobilized Cat. No Spec
proteins on microwell plates/strips. Coating Stabilizer maintains the conformation and activity of the
antibody or protein antigen portion of the dried immunoassay components. Product is filtered at 0.2
UER-CS-01 125ml
microns. UER-CS-02 500ml
Contents: Aqueous, protein-containing stabilizer and blocking solution in phosphate buffer for dried UER-CS-03 1000ml
protein components in immunoassays. Preservative: 0.02% Bromonitrodioxane, 0.02% 2-Methyl-4-
isothiazolin-3-one. pH 7.2 - 7.7
ELISA HRP stabiliser: Phosphate Buffered
This product has been developed to significantly increase the shelf life of diluted peroxidase labeled
proteins. Stability is increased at room temperature storage conditions in addition to 2- 8
centigrade. This product is subjected to 0.45 micron filtration, and contains no mercury or azide.
Cat. No Spec
This formulation insures consistently high levels of activity for both the enzyme and the antibody UER-HS-01 500ml
following long-term storage at final-use dilution. HRP Stabilizer greatly improves the signal to noise UER-HS-02 1000ml
ratios which increases the immunoassay sensitivity and offers cleaner assays.This product has been
chemically engineered to increase conjugate stability providing the customer a longer shelf life,
resistance to various shipping conditions & storage temperatures
and improved day to day assay precision.
Alk-Phos Stabilizing Diluent
This reagent is formulated specifically for Alkaline Phosphatase conjugates. The product insures
consistently high levels of activity for both the enzyme and the antibody following longterm storage Cat. No Spec
at final dilution. This product has been chemically engineered to increase conjugate stability
providing the customer a longer shelf life, resistance to various shipping conditions and storage UER-AS-01 500ml
temperatures. Alk-Phos Stabilizing Diluent is filtered at 0.2 um and reinforced with a non-mercury or UER-AS-02 1000ml
azide-free preservative. Inquire about custom vialing, labeling, kit assembly and drop shipping.
ELISA Developers KIT: HRP/AP Based
Complete "Do it Yourself" ELISA system. Contents:
The first ELISA system designed to deliver superior results to each and every research project, Blocking Buffer, HRP/AP
regardless of the level of technician expertise. Everything that is required to obtain outstanding Stabilizing Diluent, Binding Buffer,
results is included in one convenient package. Easy ELISA has been specifically developed to create Coating Stabilizer, TMB Soluble
an environment in which the researcher can be assured of consistent results with each project. All of Reagent, TMB Stop Buffer, Sample
the reagents contained in Easy ELISA are stable enough to ship at ambient temperature. Diluent, Wash Buffer (10X PBS)
Cat. No Spec
UER-1K 1 kit
Custom ELISA Reagents
All of the ELISA products are available in bulk quantities, including custom lot sizes up to 5000 liters. Ubio specializes in custom
manufacturing, vialing, labelling and packaging. E mail us for a quote
10. 2012
ubio's state-of-the-art manufacturing facility at
Kalamassery, Cochin, India can manufacture
Contract conventional diagnostic kits in addition to our
patented biochip devices. We offer contract
manufacture of all kinds of Rapid and ELISA kits on
OEM terms.
Manufacture Being a start-up, ubio is nimble and provides short
turn-around times for manufacture and a very
responsive customer-care. We can manufacture test kits even in small batches, which makes us the right
partner for firms who want to test their brand in the
market before installing a complete manufacturing
facility. ubio is the right manufacturing
For further details on our OEM service write partner for you, especially if you
to: contact@ubio.in ubio can manufacture and supply complete test kits need:
with all components including plastic containers,
droppers, printed packaging, outer cartons etc. which Variable-volume manufacture
leaves you time and money to concentrate on product
marketing
Quick introduction of new
product into the market without
initial capital investment
Protection for your investment
against market fluctuations,
ubio has full capability for the development of Immunoassays, Molecular diagnostics and Microarray obsolescence, and competition
chips for various applications. We can take up the
product development even from the development of Quick scale-up to peak demand
Assay Development at ubio
basic raw materials like recombinant protein/peptides without capital investment
or monoclonal antibodies.
Low turnaround time
Validated Technology Platforms, Our platform technologies include.
Product development using Lateral flow assays
technologies already
commercialised by ubio.
Flow through Assays
Particle Conjugation Technologies
Contract
Enzyme Linked Immunosorbant Assays
Stable Products, and flexibility in
optimisation.
Line probe and Dot probe assays
Low Density Microarrays.
Assay
Clinical validation in actual PCR-lateral Flows.
samples.
100% confidentiality.
Bead Based Assays.
Fluorescence based assays.
Development
Quantitative and semi-quantitative Assays.
Scaling up and pilot manufacturing Small molecules assays
facility
Option for further contract
manufacture
Full Technology Transfer For Further Details on our Research
Continuous support from ubio Services, Write to: to-contact@ubio.in
Team.
11. 2012
ORDERING
INFORMATION
Contact Information
ubio Biotechnology Systems Pvt Ltd,
XII-111-E/F, Technology Incubation Centre
KINFRA Hi-Tech Park, Kalamassery
Cochin, Kerala, India 683503
Tel. No: +91-484-2532966
E mail: contact@ubio.in
Web: www.ubio.in
Pricing
The prices will be quoted either in INR or USD. Quantity discounts are available for Bulk orders.
Cancellation
The orders can be cancelled within 2 days after placing the purchase order.
Payment Terms
All orders are prepaid unless prior credit arrangements have been made with us. All orders are FOB, Cochin
and freight charges and Insurance have to be borne by the customer. Special shipping charges can be
negotiated with our shipping agent for bulk orders. The payment can be made by Wire Transfer, Letter of
Credit or Bank Draft.
Our Bank Details are as follows.
For customers in India For Overseas Customers
BANK NAME AND ADDRESS : STATE BANK OF INDIA, M. BANK NAME AND ADDRESS: STANDARD
G. ROAD BRANCH, ERNAKULAM, KERALA CHARTERED BANK, ERNAKULAM BRANCH,
ACCOUNT NAME: UBIO BIOTECHNOLOGY SYSTEMS PVT. RAVIPURAM, ERNAKULAM, KERALA, INDIA.
LTD. BENEFICIARY NAME: UBIO BIOTECHNOLOGY
IFSC CODE: SBIN0003539 SYSTEMS PVT LTD
ACCOUNT NO: 30641422205 SWIFT CODE: SCBLINBBCON
BENEFICIARY ADDRESS: XII-111-E/F, TECHNOLOGY ACCOUNT NO.: 43405060909
INCUBATION CENTRE, KINFRA HI-TECH PARK, BENEFICIARY ADDRESS: XII-111-E/F,
KALAMASSERY, COCHIN, KERALA, INDIA 683503 TECHNOLOGY INCUBATION CENTRE, KINFRA HI-
TECH PARK, KALAMASSERY, COCHIN, KERALA,
INDIA 683503
Shipping
The shipments are made on FCA basis unless otherwise specified. Custom Packaging is possible on request.
Returned Goods Policy
No Return shall be accepted without prior approval from ubio.
12. 2012
ubio Biotechnology Systems Pvt Ltd
XII-111-E/F, Technology Incubation Centre, KINFRA Hi-Tech Park, Kalamassery, Cochin, Kerala, India , 683503
Ph:,+91-484-2532966/+91-9744122269, E mail: contact@ubio.in , www.ubio.in