This document discusses various types of visual hallucinations and their potential causes. It covers formed hallucinations of objects, animals, people and scenery as well as unformed hallucinations of dots, colors, flashes and geometric patterns. Potential causes discussed include temporal lobe lesions, Charles Bonnet syndrome, migraine, and occipital lobe lesions. The document also examines several occipital lobe disorders and related phenomena such as the Riddoch phenomenon, visual anosognosia, alexia, prosopagnosia, hemiachromatopsia and palinopsia. Charles Bonnet syndrome is described in detail. Finally, the document presents several examples of optical illusions.
It describes about the procedure of Hess charting. it serves as a great tool to understand the concepts involved. Suitable for optometry course. This is not a routine procedure but an important procedure which is used in diagnosis.
Hy friends thank you all of you for your love. please see my slideshare. I have made simple and easy to understand for all students. and aslo i have been present same slide on my youtube channel "optometrist Nepal" so if you have any difficult to understand visit in my channel.
It describes about the procedure of Hess charting. it serves as a great tool to understand the concepts involved. Suitable for optometry course. This is not a routine procedure but an important procedure which is used in diagnosis.
Hy friends thank you all of you for your love. please see my slideshare. I have made simple and easy to understand for all students. and aslo i have been present same slide on my youtube channel "optometrist Nepal" so if you have any difficult to understand visit in my channel.
Explore how we see. Discover that our world of perception is not about documenting reality -- it's all about survival. We do not so much "picture" what's out there as we create a world of perception.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
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This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
5. Types of Visual Hallucinations
Formed
-Objects
-Animals
-People
-Scenery
Unformed
-Dots
-Colors
-Flashes
-Geometric Patterns
6. Causes of Visual Hallucinations
(For Ophthalmology Interest)
Formed
-Temporal Lobe
Lesions
-Charles Bonnet $
Unformed
-Migraine
-Occipital Lobe
Lesions
7. Occipital Lobe Disorders Related
Phenomena
Riddoch phenomenon
Riddoch and Holmes observed that individuals recovering
from occipital lobe injuries first perceive moving objects
but not stationary ones. The Riddoch phenomenon can
be observed during confrontation field testing by
comparing the patient’s responses to moving and still
targets. More recently it has been shown that rare
patients with uni- or bilateral occipital lesions lose object
recognition but in some instances may have
“blindsight,” an unconscious ability to locate light
sources and detect moving targets in affected fields
8. Occipital Lobe Disorders Related
Phenomena
Visual Anosognosia (Anton Syndrome (
• The main characteristic of this disorder is
the denial of blindness by a patient who
obviously cannot see. • The patient acts as
though he could see, and in attempting to
walk, collides with objects, even to the
point of injury. • The lesions in cases of
negation of blindness extend beyond the
striate cortex to involve the visual
association areas.
9. Higher Visual Functions Affections
- Alexia (inability to read( with agraphia(inability to write( : occipitoparietal (dominant( Angulate
gyrus
- Alexia without agraphia : occipital cortex (dominant(
- Prosopagnosia (the inability to recognize the faces of familiar people( Occipitotemporal
- Hemiachromatopsia (Impaired color perception with relative preservation of form vision(
Occipitotemporal
- Palinopsia (Parietooccipital – migraine - LSD(
a visual disturbance defined as the persistence or recurrence of a visual image after the
stimulus has been removed.
- Visual Agnosia occipitotemporal
10. Charles Bonnet Syndrome
History
In about 1760, Charles
Bonnet, a Swiss naturalist
and philosopher, described
the vivid hallucinations
experienced by his 87-
year-old grandfather. In
1936 de Morsier (whom,
like Charles Bonnet, was a
native of Geneva
Switzerland), named the
phenomenon after Charles
Bonnet.
11. Charles Bonnet Syndrome
Initially used to designate elderly
patients with eye-related visual loss
and hallucinations, the label
Charles Bonnet syndrome has been
used as a “wastebasket” term to
describe patients with visual
hallucinations without psychiatric
disease or drug use but with
insight into the artificial nature of
their visions. Most patients with
Charles Bonnet syndrome are
elderly and have visual deficits of
varying degree due to age-related
macular degeneration, diabetic
retinopathy, glaucoma, cataracts,
and corneal disease. However,
visual loss has not been a
consistent criterion for the
diagnosis, and patients with
homonymous hemianopias and
children have also been labeled
13. Terminology meanings
(Related to Parietal Lobe Disorders)
Acalculia : loss of the ability to perform simple
calculations, typically resulting from disease or injury
of the parietal lobe of the brain.
Agraphia : is an acquired neurological disorder causing a
loss in the ability to communicate through writing
Apraxia : is a motor disorder caused by damage to the
brain (specifically the posterior parietal cortex). In
which the individual has difficulty with the motor
planning to perform tasks or movements when asked,
provided that the request or command is understood
and he/she is willing to perform the task.
15. Rotating Rings
If you stare at the dot in the center and move your head away from the screen
the rings will start to rotate. Now gradually get closer again…they change
direction!
16. Hermann Grid
This is a classic optical illusion named after Ludimar Hermann who discovered
it in 1870. At every point where the white lines intersect our eyes perceive a gray,
shadowy blob. If you look directly at one of the intersections though, the blob
disappears.
17. Scintillating Grid
This is a variation of the Hermann Grid where black dots appear and disappear
at the intersections of the gray lines. Interestingly enough, if you cock your head
at a 45 degree angle the effect is reduced (but not eliminated).
18. Monster Illusion
Found in virtually every psychology textbook in the world, the two monsters in
this optical illusion are in fact the same size. Your brain automatically adjusts
images that it perceives to be distant in order to compensate for the fact that
they are larger than they seem.
19. Jastrow Illusion
Named after Robert Jastrow in 1889, the bottom figure appears to be larger
although they are both the same size. This is because the shorter edge of “A” is
directly adjacent to the longer edge of “B”.
20. Blue vs Green
There are several variations to this optical illusion but the effect is the same. The
“blue” and “green” backgrounds are in fact the same color (open it in
photoshop).
21. Zöllner Illusion
This optical illusion was named after Johann Karl Friedrich Zöllner and consists
of parallel lines that appear to be diagonal. You may need a ruler for this one.
22. Hering Illusion
Although the two red lines seem to be bowed outwards they are perfectly
straight and parallel. This optical illusion is attributed to Ewald Hering, a German
physiologist who believed that the distortion was derived from the mind
overestimating the angles at the points of intersection.
23. Titchener Circles
Also known as the Ebbinghaus Illusion, there is still a debate in
psychological circles as to the exact mechanism and implication of this
effect. Essentially, the orange circle on the left appears to be smaller
than the one on the right although in reality they are the same size.
24. Leaning Tower
Yes, the leaning tower of pisa does actually lean, but these two images are in
fact one and the same. Although the image on the right appears to be leaning
away from the one on the left this is only in your head. Go ahead and try the
same thing with the empire state building…it will lean too, promise.
25. Static Motion
No, this is not an optical illusions GIF. The image really is static. Notice that when
you look at any individual point dead on, it will stop moving. This powerful optical
illusion is derived from interacting color contrasts and shape positions within the
image.
26. Cafe Illusion
Another famous optical illusion, this one was recently rediscovered in a cafe wall at
the bottom of St. Michael’s Hill. Although the lines appear to be diverging from one
another they are in fact quite parallel.
27. Checker Shadow Illusion
Probably one of the most unbelievable illusions out there, this one was
first optical illusions pictures published by Edward Adelson, a professor at
MIT. Although the square labeled “A” appears to be darker than the square
labeled “B”, they are actually exactly the same shade of gray. It’s okay if
you don’t believe it, we didn’t either, but Photoshop proved us wrong.
28.
29. Color Illusion
t may look as if the two arms of the "X" use different shades of red, but in
face the whole "X" only uses a single shade of red. Likewise, only one
shade of green is present throughout the image.
30. Curvature Blindness Illusion
What do you see in the center of the above image: curvy lines or zigzag
ones? Most people see both — double wavy lines and double angled lines
alternating. Now look at the lines as they appear over the black and white
area of the photo. What do you see now? The truth is all the lines are wavy.
31. Simultaneous Contrast Illusion
In this image, the horizontal bar in the middle of the picture is one solid color.
However, the changing gradient behind the bar makes it seem like the color of
the bar itself is changing as it goes from left to right. If the viewer uses their
hands to block the background, it becomes obvious that the whole bar is indeed
only one shade of gray.
32. Ponzo Illusion
The Ponzo Illusion relies on geometric shapes to trick the eye. The idea is
similar to the Simultaneous Contrast Illusion: People will make assumptions
about an object based on the information that they get from the background.
33. Rotating circles
When your eyes dart to one seemingly spinning circle, the others around
them appear to start rotating
34. All about perspective
Can you figure out which of these windows is bigger? Not only are they the
exact same size, but their tops and bottoms are also directly in line with
each other. Talk about a new perspective.
35. Spinning colors
Optical illusions like this will leave you dazed and confused. The colors
seem to be swirling around, even though it’s a still image.
38. This image is not just lines and boxes. There are 16 circles in there as well
39. You can not see all 12 of the black dots in this image at once, no matter how
hard you try
40. Long and short
Which horizontal line is shorter: the top or the bottom? Trick question—
they’re the same size, even though your mind perceives the one with
outward wings to be longer.